JP2009515180A - 粒子 - Google Patents
粒子 Download PDFInfo
- Publication number
- JP2009515180A JP2009515180A JP2008539439A JP2008539439A JP2009515180A JP 2009515180 A JP2009515180 A JP 2009515180A JP 2008539439 A JP2008539439 A JP 2008539439A JP 2008539439 A JP2008539439 A JP 2008539439A JP 2009515180 A JP2009515180 A JP 2009515180A
- Authority
- JP
- Japan
- Prior art keywords
- particles
- particle
- core
- sample
- separation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/58—Conditioning of the sorbent material or stationary liquid the sorbent moving as a whole
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/102—Process control, e.g. determination or optimization of process parameters; Programmable logic control [PLC]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1801—Radial flow
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1892—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns the sorbent material moving as a whole, e.g. continuous annular chromatography, true moving beds or centrifugal chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1894—Liquid-liquid chromatography, e.g. centrifugal partition chromatography or extraction chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1896—Membrane chromatography or membrane adsorbers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
- B01D15/206—Packing or coating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
- B01J20/3293—Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6052—Construction of the column body
- G01N30/6073—Construction of the column body in open tubular form
- G01N30/6078—Capillaries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
- B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
- G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
- G01N30/724—Nebulising, aerosol formation or ionisation
- G01N30/7266—Nebulising, aerosol formation or ionisation by electric field, e.g. electrospray
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0502485A SE0502485L (sv) | 2005-11-09 | 2005-11-09 | Partiklar |
| PCT/EP2006/068311 WO2007054548A2 (en) | 2005-11-09 | 2006-11-09 | Particles for use in a mobile solid chromatography phase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009515180A true JP2009515180A (ja) | 2009-04-09 |
| JP2009515180A5 JP2009515180A5 (enExample) | 2009-12-17 |
Family
ID=38015424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008539439A Pending JP2009515180A (ja) | 2005-11-09 | 2006-11-09 | 粒子 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20090236519A1 (enExample) |
| EP (1) | EP1963005B1 (enExample) |
| JP (1) | JP2009515180A (enExample) |
| CN (1) | CN101336133A (enExample) |
| AT (1) | ATE509697T1 (enExample) |
| SE (1) | SE0502485L (enExample) |
| WO (1) | WO2007054548A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7794837B2 (en) | 2007-08-06 | 2010-09-14 | The United States of America as represented by the Secretary of Commerce, the National Institute of Standards and Technology | Covalently immobilized fluorinated carboxylic acid stationary phase for liquid chromatography |
| AU2009238686B2 (en) * | 2008-04-22 | 2014-08-28 | Cytiva Bioprocess R&D Ab | Chromatography medium |
| US9278297B2 (en) | 2010-07-09 | 2016-03-08 | Ge Healthcare Bio-Sciences Ab | Method for ion-exchange chromatography and media used thereof |
| CN102847514B (zh) * | 2012-09-26 | 2015-06-17 | 复旦大学 | 可用作毛细管电色谱准固定相的纳米介孔材料及其制备方法 |
| US10018635B2 (en) | 2014-07-30 | 2018-07-10 | Novilytic, LLC | Method for analyzing samples of a biological fluid |
| JP6409528B2 (ja) * | 2014-11-27 | 2018-10-24 | Jnc株式会社 | アミノ基を含むイオン交換基とブチル基を含む疎水性基とを有する多孔性セルロース粒子及びそれを含むクロマトグラフィー担体ならびにb型肝炎ウィルスのウィルス様粒子の精製方法 |
| CN104741090B (zh) * | 2015-03-19 | 2017-08-29 | 深圳职业技术学院 | 一种扩张床吸附(eba)介质和其制备方法 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001514745A (ja) * | 1997-03-04 | 2001-09-11 | アメルシャム・ファルマシア・バイオテック・アクチボラグ | 分離用マトリックスおよび該マトリックスを利用した分離法 |
| JP2002529714A (ja) * | 1998-11-09 | 2002-09-10 | イルガム ナット | クロマトグラフィー分離法および選択吸着体 |
| JP2004099433A (ja) * | 2002-08-22 | 2004-04-02 | Japan Science & Technology Agency | 金属イオンで一部置換または表面担持されたリン酸カルシウム多孔質球形粒子とリン酸カルシウム多孔質多層球形粒子 |
| JP2005180938A (ja) * | 2003-12-16 | 2005-07-07 | Sumitomo Pharmaceut Co Ltd | (1−ヒドロキシエチリデン)ビス−フォスフォネートの分析方法 |
| JP2007510153A (ja) * | 2003-10-31 | 2007-04-19 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 新規分離マトリックス |
| JP2007522444A (ja) * | 2004-01-20 | 2007-08-09 | ポール・コーポレーション | 生理的イオン強度でタンパク質を吸着させるためのクロマトグラフィー材料 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4029583A (en) * | 1975-02-28 | 1977-06-14 | Purdue Research Foundation | Chromatographic supports and methods and apparatus for preparing the same |
| SE8205908D0 (sv) * | 1982-10-18 | 1982-10-18 | Pharmacia Diagnostics Ab | Sett att bilda polymerskikt |
| US5240602A (en) * | 1987-06-08 | 1993-08-31 | Chromatochem, Inc. | Chromatographic material |
| JP2761881B2 (ja) * | 1988-03-10 | 1998-06-04 | チッソ株式会社 | 抗体を固定化したアフイニテイクロマトグラフイ用担体 |
| US5043062A (en) * | 1989-02-21 | 1991-08-27 | Eastman Kodak Company | High performance affinity chromatography column comprising non-porous, nondisperse polymeric packing material |
| US5030352A (en) * | 1990-01-25 | 1991-07-09 | Purdue Research Foundation | Coated media for chromatography |
| US6039876A (en) * | 1992-07-24 | 2000-03-21 | Yang; Yan-Bo | Hydrophilic polystrene divinylbenzene based matrixes for chromatography |
| US5653875A (en) * | 1994-02-04 | 1997-08-05 | Supelco, Inc. | Nucleophilic bodies bonded to siloxane and use thereof for separations from sample matrices |
| US20010018179A1 (en) * | 1998-01-06 | 2001-08-30 | Derek J. Hei | Batch devices for the reduction of compounds from biological compositions containing cells and methods of use |
| US20020104801A1 (en) * | 1998-04-06 | 2002-08-08 | Nicolas Voute | Small dense microporous solid support materials, their preparation,and use for purification of large macromolecules and bioparticles |
| JP4750280B2 (ja) * | 1999-02-05 | 2011-08-17 | ウォーターズ・テクノロジーズ・コーポレーション | クロマトグラフィ分離のための多孔質の無機/有機ハイブリッド粒子、及び、その調製プロセス |
| SE9904272D0 (sv) * | 1999-11-25 | 1999-11-25 | Amersham Pharm Biotech Ab | A method for selective removal of a substance from samples containing compounds having nucleic acid structure |
| DE19958390A1 (de) * | 1999-12-03 | 2001-06-07 | Bayer Ag | Verfahren zur Herstellung monodisperser Adsorberharze und deren Verwendung |
| US6531523B1 (en) * | 2000-10-10 | 2003-03-11 | Renal Tech International, Llc | Method of making biocompatible polymeric adsorbing material for purification of physiological fluids of organism |
| ATE290323T1 (de) * | 2001-06-01 | 2005-03-15 | Upfront Chromatography As | Fraktionierung von proteinhaltigen mischungen |
| US20030125656A1 (en) * | 2001-12-31 | 2003-07-03 | Vadim Davankov | Hemo-and biocompatible beaded polymeric material for purification of physiological fluids of organism, method of producing the material, as well as method of and device for purification of physiological fluids of organism with use of the material |
| SE525599C2 (sv) * | 2002-04-11 | 2005-03-15 | Staffan Nilsson | Analys och separation av provkomponenter |
| FR2838655B1 (fr) * | 2002-04-23 | 2004-06-25 | Centre Nat Rech Scient | Capsules composites complexantes |
| SE0202551D0 (sv) * | 2002-08-27 | 2002-08-27 | Amersham Biosciences Ab | Chromatographic two-layer particles |
| US6909091B2 (en) | 2003-05-30 | 2005-06-21 | Nanosep Ab | Separation and analysis of sample components |
| CN100434357C (zh) * | 2003-08-22 | 2008-11-19 | 独立行政法人物质·材料研究机构 | 用金属离子部分取代或表面担载金属离子的磷酸钙多孔质多层球形粒子 |
| US8137548B2 (en) * | 2003-10-17 | 2012-03-20 | Zirchrom Separations, Inc. | Chelator-modified inorganic oxide particles |
| DE602005024099D1 (de) * | 2004-01-28 | 2010-11-25 | Dainippon Ink & Chemicals | Verfahren zur herstellung eines kern-schale-harzteilchens mit hoher flüssigkeitsabsorption |
| US20050181378A1 (en) * | 2004-02-18 | 2005-08-18 | Applera Corporation | Polyelectrolyte-coated size-exclusion ion-exchange particles |
| JP3809177B2 (ja) * | 2004-05-24 | 2006-08-16 | 株式会社資生堂 | アフィニティー粒子及びアフィニティー分離方法 |
-
2005
- 2005-11-09 SE SE0502485A patent/SE0502485L/xx not_active Application Discontinuation
-
2006
- 2006-11-09 EP EP06829967A patent/EP1963005B1/en not_active Not-in-force
- 2006-11-09 AT AT06829967T patent/ATE509697T1/de not_active IP Right Cessation
- 2006-11-09 US US12/093,085 patent/US20090236519A1/en not_active Abandoned
- 2006-11-09 WO PCT/EP2006/068311 patent/WO2007054548A2/en not_active Ceased
- 2006-11-09 JP JP2008539439A patent/JP2009515180A/ja active Pending
- 2006-11-09 CN CNA200680048662XA patent/CN101336133A/zh active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001514745A (ja) * | 1997-03-04 | 2001-09-11 | アメルシャム・ファルマシア・バイオテック・アクチボラグ | 分離用マトリックスおよび該マトリックスを利用した分離法 |
| JP2002529714A (ja) * | 1998-11-09 | 2002-09-10 | イルガム ナット | クロマトグラフィー分離法および選択吸着体 |
| JP2004099433A (ja) * | 2002-08-22 | 2004-04-02 | Japan Science & Technology Agency | 金属イオンで一部置換または表面担持されたリン酸カルシウム多孔質球形粒子とリン酸カルシウム多孔質多層球形粒子 |
| JP2007510153A (ja) * | 2003-10-31 | 2007-04-19 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 新規分離マトリックス |
| JP2005180938A (ja) * | 2003-12-16 | 2005-07-07 | Sumitomo Pharmaceut Co Ltd | (1−ヒドロキシエチリデン)ビス−フォスフォネートの分析方法 |
| JP2007522444A (ja) * | 2004-01-20 | 2007-08-09 | ポール・コーポレーション | 生理的イオン強度でタンパク質を吸着させるためのクロマトグラフィー材料 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007054548A3 (en) | 2007-09-20 |
| WO2007054548A2 (en) | 2007-05-18 |
| EP1963005A2 (en) | 2008-09-03 |
| US20090236519A1 (en) | 2009-09-24 |
| SE0502485L (sv) | 2007-05-10 |
| EP1963005B1 (en) | 2011-05-18 |
| CN101336133A (zh) | 2008-12-31 |
| ATE509697T1 (de) | 2011-06-15 |
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