JP2009514966A - 高リン血症のためのマグネシウム含有重合体 - Google Patents

高リン血症のためのマグネシウム含有重合体 Download PDF

Info

Publication number
JP2009514966A
JP2009514966A JP2008540139A JP2008540139A JP2009514966A JP 2009514966 A JP2009514966 A JP 2009514966A JP 2008540139 A JP2008540139 A JP 2008540139A JP 2008540139 A JP2008540139 A JP 2008540139A JP 2009514966 A JP2009514966 A JP 2009514966A
Authority
JP
Japan
Prior art keywords
magnesium
pharmaceutical composition
aliphatic amine
amine polymer
crosslinked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2008540139A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009514966A5 (enExample
Inventor
チャド シー. ヒューバル,
プラディープ ケー. ダール,
スティーブン ランダル ホルムズ−ファーリー,
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genzyme Corp
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of JP2009514966A publication Critical patent/JP2009514966A/ja
Publication of JP2009514966A5 publication Critical patent/JP2009514966A5/ja
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/132Amines having two or more amino groups, e.g. spermidine, putrescine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2008540139A 2005-11-08 2006-11-07 高リン血症のためのマグネシウム含有重合体 Withdrawn JP2009514966A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73459305P 2005-11-08 2005-11-08
PCT/US2006/043402 WO2007056405A2 (en) 2005-11-08 2006-11-07 Magnesium-containing polymers for the treatment of hyperphosphatemia

Publications (2)

Publication Number Publication Date
JP2009514966A true JP2009514966A (ja) 2009-04-09
JP2009514966A5 JP2009514966A5 (enExample) 2009-12-24

Family

ID=37888157

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008540139A Withdrawn JP2009514966A (ja) 2005-11-08 2006-11-07 高リン血症のためのマグネシウム含有重合体

Country Status (8)

Country Link
US (1) US20090162314A1 (enExample)
EP (1) EP1945196A2 (enExample)
JP (1) JP2009514966A (enExample)
CN (1) CN101304739A (enExample)
AR (1) AR060690A1 (enExample)
BR (1) BRPI0618352A2 (enExample)
CA (1) CA2626734A1 (enExample)
WO (1) WO2007056405A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019065958A1 (ja) * 2017-09-29 2019-04-04 第一三共株式会社 ジカルボン酸化合物とリン吸着剤との組み合わせ

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010117370A1 (en) * 2009-04-10 2010-10-14 Cypress Pharmaceuticals, Inc. Phosphate-binding magnesium salts and uses thereof
US8247000B2 (en) 2009-04-10 2012-08-21 Cypress Pharmaceutical, Inc. Phosphate-binding magnesium salts and uses thereof
CN103159880B (zh) * 2011-12-14 2016-06-22 上海亿法医药科技有限公司 碳酸司维拉姆的制备方法
US9394318B2 (en) 2012-11-30 2016-07-19 Cypress Pharmaceuticals, Inc. Crystal polymorph of magnesium glycinate dihydrate and process for its preparation
KR102633597B1 (ko) 2013-06-05 2024-02-06 트리시다, 인크. 경구 투여를 위한 양성자-결합 중합체
KR20240008418A (ko) * 2014-12-10 2024-01-18 트리시다, 인크. 경구 투여용 양성자-결합 폴리머
US9649335B1 (en) * 2016-03-30 2017-05-16 Baylor University Intravenous administration of an oxygen-enabled fluid
AU2017261337A1 (en) 2016-05-06 2018-11-15 Tricida, Inc. Compositions for and method of treating acid-base disorders
BR112019013364A2 (pt) 2016-12-28 2020-04-14 Fujifilm Corp emulsão de polímero contendo átomo de nitrogênio ou sal do mesmo, método de produção para o mesmo e método de produção para partículas
TW201922267A (zh) 2017-10-16 2019-06-16 日商富士軟片股份有限公司 高磷血症治療劑
US11266684B2 (en) 2017-11-03 2022-03-08 Tricida, Inc. Compositions for and method of treating acid-base disorders

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2456428A (en) * 1944-10-11 1948-12-14 Shell Dev Polyallyl amine and related polymeric amines
US3104205A (en) * 1959-12-17 1963-09-17 Warner Lambert Pharmaceutical Deodorant composition comprising the copper complex of the copolymer of allylamine and methacrylic acid
US3308020A (en) * 1961-09-22 1967-03-07 Merck & Co Inc Compositions and method for binding bile acids in vivo including hypocholesteremics
US3332841A (en) * 1961-10-04 1967-07-25 Lilly Co Eli Method of treating hyperacidity
US3624209A (en) * 1966-12-28 1971-11-30 Bristol Myers Co Composition for treatment of gastro-intestinal disorders
US3980770A (en) * 1971-06-04 1976-09-14 Pharmacia Aktiebolag Polymerization products containing amino groups useful in serum cholesterol level control
US4205064A (en) * 1973-06-11 1980-05-27 Merck & Co., Inc. Bile acid sequestering composition containing poly[{alkyl-(3-ammoniopropyl)imino}-trimethylenedihalides]
US4181718A (en) * 1975-12-29 1980-01-01 Mason Norbert S Polyanion-stabilized aluminum hydrogels
US4071478A (en) * 1976-06-07 1978-01-31 Merck & Co., Inc. Controlled partially cross-linked 3,3-ionenes
US4143130A (en) * 1977-08-29 1979-03-06 Warren-Teed Laboratories, Inc. Method for treating kidney stones
US4247393A (en) * 1979-01-11 1981-01-27 Wallace Richard A Hemodialysis assist device
US4344993A (en) * 1980-09-02 1982-08-17 The Dow Chemical Company Perfluorocarbon-polymeric coatings having low critical surface tensions
US4504640A (en) * 1982-05-19 1985-03-12 Nitto Boseki Co., Ltd. Process for producing monoallylamine polymer
DE3241113A1 (de) * 1982-11-06 1984-05-10 Bayer Ag, 5090 Leverkusen Vakzinen mit zuschlagstoffen
JPS6090243A (ja) * 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
US4540760A (en) * 1984-01-11 1985-09-10 Nitto Boseki Co. Ltd. Process for producing polymers of monoallylamine
DE3402878A1 (de) * 1984-01-27 1985-08-01 Algina AG, Zug Arzneimittel und die verwendung schwerloeslicher calcium- und/oder magnesiumverbindungen als arzneimittel
US4631305A (en) * 1985-03-22 1986-12-23 The Upjohn Company Polymeric material as a disintegrant in a compressed tablet
DE3541511A1 (de) * 1985-11-19 1987-05-21 Grace W R Ab Promoter fuer die papierleimung, verfahren zu dessen herstellung und dessen verwendung
US6274713B1 (en) * 1989-04-07 2001-08-14 Salutar, Inc. Polychelants
US5236701A (en) * 1989-07-19 1993-08-17 Lowchol Scientific Inc. Ingestible hydrophilic polymeric amines useful for lowering blood cholesterol
US5053423A (en) * 1990-03-22 1991-10-01 Quadra Logic Technologies Inc. Compositions for photodynamic therapy
US5055197A (en) * 1991-04-05 1991-10-08 Rohm And Haas Company Process for removing residual monomers and oligemers from amine-containing polymers
US5108767A (en) * 1991-06-10 1992-04-28 Abbott Laboratories Liquid nutritional product for persons receiving renal dialysis
ES2096150T3 (es) * 1992-07-22 1997-03-01 Hoechst Ag Copolimeros vinilicos reticulados, procedimiento para su preparacion, asi como el empleo de estos compuestos.
DK0580078T3 (da) * 1992-07-22 1998-05-25 Hoechst Ag Polyvinylamin-derivater med hydrofyle centrer,fremgangsmåde til deres fremstilling samt anvendelse af forbindelserne som lægemidler, bærere af aktive stoffer og næringsmiddelhjælpestof.
US5302531A (en) * 1992-10-22 1994-04-12 Miles Inc. Composition for the semiquantitative determination of specific gravity of a test sample
US5487888A (en) * 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5929184A (en) * 1993-06-02 1999-07-27 Geltex Pharmaceuticals, Inc. Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
US5496545A (en) * 1993-08-11 1996-03-05 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5667775A (en) * 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
US5414068A (en) * 1994-01-24 1995-05-09 Rohm And Haas Company Crosslinked anion exchange particles and method for producing the particles
EP0922461A4 (en) * 1996-07-19 2002-07-17 Nikken Chemicals Co Ltd MEDICINE AGAINST HYPERPHOSPHATANEMIA
US5753706A (en) * 1996-12-16 1998-05-19 Hsu; Chen Hsing Methods for treating renal failure
GB9720061D0 (en) * 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
US5985938A (en) * 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US6566407B2 (en) * 1997-11-05 2003-05-20 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US6410616B1 (en) * 1998-04-09 2002-06-25 Nippon Shokubai Co., Ltd Crosslinked polymer particle and its production process and use
DE19835467A1 (de) * 1998-08-06 2000-02-17 Elenac Gmbh Feststoffreaktor mit antistatischer Beschichtung zur Durchführung von Reaktionen in der Gasphase
DE19917705C1 (de) * 1999-04-20 2000-12-28 Vitasyn Gmbh Mittel zur Therapie von Hyperphosphatämie
US6733780B1 (en) * 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
AU2001289699B2 (en) * 2000-07-28 2006-06-01 Cheplapharm Arzneimittel Gmbh New pharmaceutical composition
ES2304437T3 (es) * 2001-04-18 2008-10-16 Genzyme Corporation Uso de colesevelam o de hidrocloruro de sevelamer para reducir la glucosa serica.
WO2002085380A1 (en) * 2001-04-18 2002-10-31 Geltex Pharmaceuticals, Inc. Method for treating gout and reducing serum uric acid
BR0209133A (pt) * 2001-04-18 2004-06-15 Genzyme Corp Método para tratar gota e para reduzir os nìveis de ácido úrico n0 sangue
WO2002085379A1 (en) * 2001-04-18 2002-10-31 Geltex Pharmaceuticals, Inc. Method for improving vascular access in patients with vascular shunts
WO2003053932A1 (en) * 2001-12-21 2003-07-03 Tohru Koike Zinc complexes capable of scavenging substances bearing anionic substituents
US20040115265A1 (en) * 2002-12-11 2004-06-17 Loutfy Benkerrour Multilayered tablet containing pravastatin and aspirin and method
WO2004085448A2 (en) * 2003-03-19 2004-10-07 Genzyme Corporation Unsaturated phosphinyl-phosphonate phosphate transport inhibitors
AU2004311849B2 (en) * 2003-12-31 2009-04-02 Genzyme Corporation Enteric coated aliphatic amine polymer bile acid sequestrants
US7019085B2 (en) * 2004-08-30 2006-03-28 Albright Robert L Phosphate selective resin and related methods
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
US7985418B2 (en) * 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019065958A1 (ja) * 2017-09-29 2019-04-04 第一三共株式会社 ジカルボン酸化合物とリン吸着剤との組み合わせ

Also Published As

Publication number Publication date
WO2007056405A2 (en) 2007-05-18
WO2007056405A3 (en) 2007-11-08
AR060690A1 (es) 2008-07-10
BRPI0618352A2 (pt) 2011-08-23
CN101304739A (zh) 2008-11-12
US20090162314A1 (en) 2009-06-25
WO2007056405A8 (en) 2007-08-02
EP1945196A2 (en) 2008-07-23
CA2626734A1 (en) 2007-05-18

Similar Documents

Publication Publication Date Title
JP6029736B2 (ja) アミンポリマー用サシェ製剤
US20090304623A1 (en) Once A Day Formulation for Phosphate Binders
JP4499363B2 (ja) 血清グルコースの減少方法
US5667775A (en) Phosphate-binding polymers for oral administration
EP3167878B1 (en) Aliphatic amine polymer salts for tableting
US20080014288A1 (en) Zinc-containing treatments for hyperphosphatemia
US20100135950A1 (en) Iron(II)-Containing Treatments for Hyperphosphatemia
JP2009514966A (ja) 高リン血症のためのマグネシウム含有重合体
CA2658338A1 (en) Amine dendrimers
EP2152277A1 (en) Amido-amine dendrimer compositions
AU2012200480B2 (en) "Aliphatic amine polymer salts for tableting"

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20091104

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20091104

A072 Dismissal of procedure [no reply to invitation to correct request for examination]

Free format text: JAPANESE INTERMEDIATE CODE: A073

Effective date: 20110314

A300 Application deemed to be withdrawn because no request for examination was validly filed

Free format text: JAPANESE INTERMEDIATE CODE: A300

Effective date: 20110405