JP2009513712A5 - - Google Patents
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- Publication number
- JP2009513712A5 JP2009513712A5 JP2008538984A JP2008538984A JP2009513712A5 JP 2009513712 A5 JP2009513712 A5 JP 2009513712A5 JP 2008538984 A JP2008538984 A JP 2008538984A JP 2008538984 A JP2008538984 A JP 2008538984A JP 2009513712 A5 JP2009513712 A5 JP 2009513712A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- disease
- composition
- human
- inflammatory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73258005P | 2005-11-01 | 2005-11-01 | |
| PCT/US2006/042601 WO2007053661A2 (en) | 2005-11-01 | 2006-11-01 | Uses of anti-cd40 antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009513712A JP2009513712A (ja) | 2009-04-02 |
| JP2009513712A5 true JP2009513712A5 (https=) | 2010-12-09 |
Family
ID=38006484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008538984A Pending JP2009513712A (ja) | 2005-11-01 | 2006-11-01 | 抗cd40抗体の使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20090202531A1 (https=) |
| EP (1) | EP1957538B1 (https=) |
| JP (1) | JP2009513712A (https=) |
| KR (1) | KR101395005B1 (https=) |
| CN (1) | CN101351478A (https=) |
| AU (1) | AU2006308860B2 (https=) |
| BR (1) | BRPI0618217A2 (https=) |
| CA (1) | CA2627891A1 (https=) |
| ES (1) | ES2428089T3 (https=) |
| IL (1) | IL191117A (https=) |
| RU (1) | RU2442606C2 (https=) |
| WO (1) | WO2007053661A2 (https=) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| US8926979B2 (en) | 2005-11-01 | 2015-01-06 | Novartis Ag | Treatment of cancer or pre-malignant conditions using anti-CD40 antibodies |
| PL2289909T3 (pl) | 2005-11-30 | 2015-04-30 | Abbvie Inc | Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał |
| RU2432362C2 (ru) | 2005-11-30 | 2011-10-27 | Эбботт Лэборетриз | Моноклональные антитела и их применения |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| EP2124952A2 (en) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
| EP2077281A1 (en) * | 2008-01-02 | 2009-07-08 | Bergen Teknologioverforing AS | Anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome |
| ES2630226T3 (es) | 2009-01-06 | 2017-08-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Un agente agotador de células B para el tratamiento de la aterosclerosis |
| CA2767616A1 (en) | 2009-07-09 | 2011-01-13 | The Scripps Research Institute | Gene expression profiles associated with chronic allograft nephropathy |
| ES2684475T3 (es) | 2010-04-15 | 2018-10-03 | Abbvie Inc. | Proteínas que se unen a beta amiloide |
| RU2509573C2 (ru) * | 2010-07-27 | 2014-03-20 | Олег Ильич Эпштейн | Лекарственное средство для лечения рассеянного склероза и способ лечения рассеянного склероза |
| RU2441023C1 (ru) * | 2010-07-15 | 2012-01-27 | Олег Ильич Эпштейн | Лекарственное средство для лечения рассеянного склероза и способ лечения рассеянного склероза |
| CN103298833B (zh) | 2010-08-14 | 2015-12-16 | Abbvie公司 | β淀粉样蛋白结合蛋白 |
| AR083847A1 (es) | 2010-11-15 | 2013-03-27 | Novartis Ag | Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40 |
| WO2012075111A1 (en) | 2010-11-30 | 2012-06-07 | Novartis Ag | Uses of anti-cd40 antibodies in combination therapy for b cell-related cancers |
| HUE065915T2 (hu) | 2011-03-11 | 2024-06-28 | Beth Israel Deaconess Medical Ct Inc | Anti-CD40 antitestek és alkalmazásaik |
| CN113461819B (zh) | 2011-04-29 | 2024-01-02 | 埃派斯进有限公司 | 抗-cd40抗体及其使用方法 |
| WO2012174535A1 (en) * | 2011-06-17 | 2012-12-20 | Constitution Medical, Inc. | Solutions for histoprocessing of biological samples |
| US20140004131A1 (en) | 2012-05-04 | 2014-01-02 | Novartis Ag | Antibody formulation |
| AU2013337903B2 (en) | 2012-10-30 | 2018-08-16 | Apexigen, Inc. | Anti-CD40 antibodies and methods of use |
| CN108025068A (zh) * | 2014-03-12 | 2018-05-11 | 耶达研究与开发有限公司 | 降低系统性调节性t细胞水平或活性来治疗cns的疾病和损伤 |
| US10519237B2 (en) | 2014-03-12 | 2019-12-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| AU2015228372B2 (en) | 2014-03-12 | 2018-05-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| US10618963B2 (en) | 2014-03-12 | 2020-04-14 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| US10443100B2 (en) | 2014-05-22 | 2019-10-15 | The Scripps Research Institute | Gene expression profiles associated with sub-clinical kidney transplant rejection |
| US11104951B2 (en) | 2014-05-22 | 2021-08-31 | The Scripps Research Institute | Molecular signatures for distinguishing liver transplant rejections or injuries |
| AU2015360502A1 (en) | 2014-12-10 | 2017-06-29 | Regents Of The University Of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
| US10174121B2 (en) | 2015-05-29 | 2019-01-08 | Abbvie, Inc. | Anti-CD40 antibodies |
| WO2017040932A1 (en) | 2015-09-04 | 2017-03-09 | Primatope Therapeutics Inc. | Humanized anti-cd40 antibodies and uses thereof |
| CR20180177A (es) * | 2015-09-30 | 2018-06-22 | Janssen Biotech Inc | Anticuerpos agonistas que se unen específicamente a cd40 humana y método de uso |
| KR102379464B1 (ko) | 2016-06-20 | 2022-03-29 | 키맵 리미티드 | 항-pd-l1 항체 |
| WO2018222019A1 (ko) * | 2017-06-01 | 2018-12-06 | 서울대학교 산학협력단 | 신규한 항-cd40 항체 및 이의 용도 |
| CN112638375A (zh) | 2018-06-15 | 2021-04-09 | 旗舰创业创新五公司 | 通过后细胞信号传导因子的调节来增加免疫活性 |
| WO2020227159A2 (en) | 2019-05-03 | 2020-11-12 | Flagship Pioneering Innovations V, Inc. | Methods of modulating immune activity |
| JP2023509359A (ja) | 2019-12-17 | 2023-03-08 | フラグシップ パイオニアリング イノベーションズ ブイ,インコーポレーテッド | 鉄依存性細胞分解の誘導物質との併用抗癌療法 |
| JP2023532339A (ja) | 2020-06-29 | 2023-07-27 | フラグシップ パイオニアリング イノベーションズ ブイ,インコーポレーテッド | サノトランスミッションを促進するためにエンジニアリングされたウイルス及び癌の処置におけるそれらの使用 |
| WO2022120038A1 (en) * | 2020-12-02 | 2022-06-09 | Albert Einstein College Of Medicine | Method for predicting patient response to cd40-targeted therapies |
| JP2024512669A (ja) | 2021-03-31 | 2024-03-19 | フラグシップ パイオニアリング イノベーションズ ブイ,インコーポレーテッド | タノトランスミッションポリペプチド及び癌の処置におけるそれらの使用 |
| US20240316104A1 (en) | 2021-06-29 | 2024-09-26 | Flagship Pioneering Innovations V, Inc. | Immune cells engineered to promote thanotransmission and uses thereof |
| WO2023284714A1 (zh) * | 2021-07-14 | 2023-01-19 | 舒泰神(北京)生物制药股份有限公司 | 特异性识别cd40的抗体及其应用 |
| US12234294B2 (en) | 2021-11-05 | 2025-02-25 | Kiniksa Pharmaceuticals, Gmbh | Pharmaceutical composition of a humanized anti-CD40 antibody |
| KR20250005109A (ko) * | 2022-04-15 | 2025-01-09 | 바이오사이토젠 파마슈티컬스 (베이징) 컴퍼니 리미티드 | 항-cd40 항체 및 이의 용도 |
| WO2024077191A1 (en) | 2022-10-05 | 2024-04-11 | Flagship Pioneering Innovations V, Inc. | Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer |
| WO2024151687A1 (en) | 2023-01-09 | 2024-07-18 | Flagship Pioneering Innovations V, Inc. | Genetic switches and their use in treating cancer |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6136310A (en) * | 1991-07-25 | 2000-10-24 | Idec Pharmaceuticals Corporation | Recombinant anti-CD4 antibodies for human therapy |
| US5874082A (en) * | 1992-07-09 | 1999-02-23 | Chiron Corporation | Humanized anti-CD40 monoclonal antibodies and fragments capable of blocking B cell proliferation |
| ES2211884T3 (es) * | 1993-10-01 | 2004-07-16 | Immunex Corporation | Anticuerpos contra el cd40. |
| US6946129B1 (en) * | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
| US7063845B2 (en) * | 2000-04-28 | 2006-06-20 | Gemini Science, Inc. | Human anti-CD40 antibodies |
| AU2002346999B2 (en) * | 2001-10-19 | 2007-11-08 | Centre Hospitalier Regional Et Universitaire De Tours | Methods and compositions to evaluate antibody treatment response |
| EP2062916A3 (en) * | 2003-04-09 | 2009-08-19 | Genentech, Inc. | Therapy of autoimmune disease in a patient with an inadequate response to a TNF-Alpha inhibitor |
| PT1694360E (pt) * | 2003-11-04 | 2010-12-13 | Novartis Vaccines & Diagnostic | Utilização de anticorpos monoclonais antagonistas anti-cd40 para o tratamento de doenças auto-imunes e inflamatórias e da rejeição ao transplante de orgãos |
| EP1844815B1 (en) * | 2003-11-04 | 2011-09-14 | Novartis Vaccines and Diagnostics, Inc. | Combination therapy comprising anti-CD20 and anti-CD40 antibodies for the treatment of B cell-related cancers |
| EP1680141B8 (en) * | 2003-11-04 | 2011-01-12 | Novartis Vaccines and Diagnostics, Inc. | Methods of therapy for solid tumors expressing the cd40 cell-surface antigen |
| CA2544951A1 (en) * | 2003-11-04 | 2005-05-19 | Chiron Corporation | Use of antagonist anti-cd40 monoclonal antibodies for treatment of multiple myeloma |
| ATE474598T1 (de) * | 2003-11-04 | 2010-08-15 | Novartis Vaccines & Diagnostic | Verwendung von antagonisten-anti-cd40-antikörpern zur behandlung von chronisch lymphozytischer leukämie |
| US20070231813A1 (en) * | 2004-06-01 | 2007-10-04 | Centre Hospitalier Regional Et Universitaire De Tours | Fcgr3a Gebotype and Methods for Evaluating Treatment Response to Non-Depleting Antibodies |
| US20080057070A1 (en) * | 2004-11-04 | 2008-03-06 | Chiron Corporation | Antagonist Anti-Cd40 Monoclonal Antibodies and Methods for Their Use |
-
2006
- 2006-11-01 JP JP2008538984A patent/JP2009513712A/ja active Pending
- 2006-11-01 EP EP06836747.3A patent/EP1957538B1/en active Active
- 2006-11-01 KR KR1020087012998A patent/KR101395005B1/ko not_active Expired - Fee Related
- 2006-11-01 WO PCT/US2006/042601 patent/WO2007053661A2/en not_active Ceased
- 2006-11-01 BR BRPI0618217-8A patent/BRPI0618217A2/pt not_active IP Right Cessation
- 2006-11-01 RU RU2008121899/15A patent/RU2442606C2/ru not_active IP Right Cessation
- 2006-11-01 CN CNA2006800501259A patent/CN101351478A/zh active Pending
- 2006-11-01 US US12/092,256 patent/US20090202531A1/en not_active Abandoned
- 2006-11-01 ES ES06836747T patent/ES2428089T3/es active Active
- 2006-11-01 CA CA002627891A patent/CA2627891A1/en not_active Abandoned
- 2006-11-01 AU AU2006308860A patent/AU2006308860B2/en not_active Ceased
-
2008
- 2008-04-28 IL IL191117A patent/IL191117A/en not_active IP Right Cessation
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