JP2009511034A5 - - Google Patents
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- Publication number
- JP2009511034A5 JP2009511034A5 JP2008535031A JP2008535031A JP2009511034A5 JP 2009511034 A5 JP2009511034 A5 JP 2009511034A5 JP 2008535031 A JP2008535031 A JP 2008535031A JP 2008535031 A JP2008535031 A JP 2008535031A JP 2009511034 A5 JP2009511034 A5 JP 2009511034A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- nucleotides
- independently selected
- integer
- uuu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72630505P | 2005-10-12 | 2005-10-12 | |
| US75191705P | 2005-12-20 | 2005-12-20 | |
| PCT/EP2006/067334 WO2007042554A2 (en) | 2005-10-12 | 2006-10-12 | Methods and compositions for treating immune disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009511034A JP2009511034A (ja) | 2009-03-19 |
| JP2009511034A5 true JP2009511034A5 (https=) | 2009-11-26 |
Family
ID=37770873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008535031A Pending JP2009511034A (ja) | 2005-10-12 | 2006-10-12 | 免疫異常を治療するための方法および組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20090169472A1 (https=) |
| EP (1) | EP1937812A2 (https=) |
| JP (1) | JP2009511034A (https=) |
| KR (1) | KR20080065656A (https=) |
| AU (1) | AU2006301230A1 (https=) |
| BR (1) | BRPI0617254A2 (https=) |
| CA (1) | CA2625488A1 (https=) |
| EA (1) | EA200801045A1 (https=) |
| WO (1) | WO2007042554A2 (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6207646B1 (en) * | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| PL1957647T3 (pl) | 2005-11-25 | 2015-07-31 | Zoetis Belgium S A | Oligorybonukleotydy immunostymulujące |
| PT2347775T (pt) | 2005-12-13 | 2020-07-14 | The President And Fellows Of Harvard College | Estruturas em andaime para transplante celular |
| US7985538B2 (en) | 2006-02-23 | 2011-07-26 | Yale University | Drug resistance and methods of reversing |
| AU2007280690C1 (en) | 2006-07-31 | 2012-08-23 | Curevac Gmbh | Nucleic acid of formula (I): GIXmGn, or (II): CIXmCn, in particular as an immune-stimulating agent/adjuvant |
| DE102006035618A1 (de) * | 2006-07-31 | 2008-02-07 | Curevac Gmbh | Nukleinsäure der Formel (I): GlXmGn, insbesondere als immunstimulierendes Adjuvanz |
| KR101438245B1 (ko) * | 2006-08-23 | 2014-09-04 | 쿠도스 파마슈티칼스 리미티드 | Ｍｔｏｒ 억제제로서의 2-메틸모르폴린 피리도-, 피라조- 및 피리미도-피리미딘 유도체 |
| EP2068912A2 (en) * | 2006-09-27 | 2009-06-17 | Coley Pharmaceutical Group, Inc. | Compositions of tlr ligands and antivirals |
| WO2009030254A1 (en) | 2007-09-04 | 2009-03-12 | Curevac Gmbh | Complexes of rna and cationic peptides for transfection and for immunostimulation |
| JP5753382B2 (ja) * | 2007-11-06 | 2015-07-22 | アディウティーダ ファーマシューティカルズ ゲーエムベーハー | 修飾されたオリゴリン酸基を含有する免疫賦活オリゴリボヌクレオチドアナログ |
| EP2176408B9 (en) * | 2008-01-31 | 2015-11-11 | Curevac GmbH | NUCLEIC ACIDS COMPRISING FORMULA (NuGiXmGnNv)a AND DERIVATIVES THEREOF AS AN IMMUNOSTIMULATING AGENTS /ADJUVANTS |
| US10328133B2 (en) * | 2008-02-13 | 2019-06-25 | President And Fellows Of Harvard College | Continuous cell programming devices |
| EP2316032A1 (en) | 2008-08-20 | 2011-05-04 | INSERM - Institut National de la Santé et de la Recherche Médicale | Methods for predicting the response to anti-cancer treatment with an agonist of tlr7 or an agonist of tlr8 |
| WO2010037408A1 (en) | 2008-09-30 | 2010-04-08 | Curevac Gmbh | Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof |
| US20110053829A1 (en) | 2009-09-03 | 2011-03-03 | Curevac Gmbh | Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids |
| CA2801523C (en) | 2010-07-30 | 2021-08-03 | Curevac Gmbh | Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation |
| JP6104806B2 (ja) | 2010-10-06 | 2017-03-29 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 材料に基づく細胞治療のための注射可能孔形成性ハイドロゲル |
| GB201021867D0 (en) | 2010-12-23 | 2011-02-02 | Mologen Ag | Non-coding immunomodulatory DNA construct |
| US9675561B2 (en) | 2011-04-28 | 2017-06-13 | President And Fellows Of Harvard College | Injectable cryogel vaccine devices and methods of use thereof |
| WO2013113326A1 (en) | 2012-01-31 | 2013-08-08 | Curevac Gmbh | Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen |
| CN104244929B (zh) | 2012-04-16 | 2017-04-05 | 哈佛学院董事会 | 用于调节免疫反应的介孔二氧化硅组合物 |
| US9228184B2 (en) | 2012-09-29 | 2016-01-05 | Dynavax Technologies Corporation | Human toll-like receptor inhibitors and methods of use thereof |
| US9868955B2 (en) | 2012-09-29 | 2018-01-16 | Dynavax Technologies Corporation | Human toll-like receptor inhibitors and methods of use thereof |
| KR101441415B1 (ko) * | 2013-03-11 | 2014-09-24 | 국방과학연구소 | 신규한 ｓｉＲＮＡ, 이를 이용한 오소폭스바이러스에 대한 항바이러스 조성물 |
| BR112016003361A2 (pt) | 2013-08-21 | 2017-11-21 | Curevac Ag | vacina do vírus sincicial respiratório (rsv) |
| CA2936286A1 (en) | 2014-04-01 | 2015-10-08 | Curevac Ag | Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant |
| JP7348708B2 (ja) | 2014-04-30 | 2023-09-21 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 組み合わせワクチン装置および癌細胞を殺滅する方法 |
| KR101643947B1 (ko) * | 2014-06-27 | 2016-07-29 | 건국대학교 산학협력단 | gHA1 단백질에 특이적으로 결합하는 RNA 앱타머 및 그를 포함하는 약학 조성물 |
| HK1247861A1 (zh) | 2015-01-30 | 2018-10-05 | President And Fellows Of Harvard College | 用於癌症治疗的肿瘤周围和肿瘤内部材料 |
| WO2016164705A1 (en) | 2015-04-10 | 2016-10-13 | Omar Abdel-Rahman Ali | Immune cell trapping devices and methods for making and using the same |
| LU92821B1 (en) | 2015-09-09 | 2017-03-20 | Mologen Ag | Combination comprising immunostimulatory oligonucleotides |
| GB2542425A (en) | 2015-09-21 | 2017-03-22 | Mologen Ag | Means for the treatment of HIV |
| EP3411475B1 (en) | 2016-02-06 | 2025-08-27 | President and Fellows of Harvard College | Recapitulating the hematopoietic niche to reconstitute immunity |
| CN115404196A (zh) | 2016-07-13 | 2022-11-29 | 哈佛学院院长等 | 抗原呈递细胞模拟支架及其制备和使用方法 |
| CN110418651A (zh) | 2016-08-02 | 2019-11-05 | 哈佛学院院长等 | 用于调节免疫应答的生物材料 |
| JP2020531555A (ja) * | 2017-08-31 | 2020-11-05 | モロゲン・アーゲー | 腫瘍微小環境のモジュレーションのためのｔｌｒ−９アゴニスト |
| WO2020061129A1 (en) | 2018-09-19 | 2020-03-26 | President And Fellows Of Harvard College | Compositions and methods for labeling and modulation of cells in vitro and in vivo |
| WO2021061837A1 (en) | 2019-09-23 | 2021-04-01 | President And Fellows Of Harvard College | Biomaterial-based antigen free vaccine and the use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5683874A (en) * | 1991-03-27 | 1997-11-04 | Research Corporation Technologies, Inc. | Single-stranded circular oligonucleotides capable of forming a triplex with a target sequence |
| FR2814370B1 (fr) * | 2000-09-22 | 2004-08-20 | Centre Nat Rech Scient | Utilisation d'un complexe acide nucleique/pei pour le ciblage de cellules souches du cerveau |
| US8153141B2 (en) * | 2002-04-04 | 2012-04-10 | Coley Pharmaceutical Gmbh | Immunostimulatory G, U-containing oligoribonucleotides |
| WO2005097993A2 (en) * | 2004-02-19 | 2005-10-20 | Coley Pharmaceutical Group, Inc. | Immunostimulatory viral rna oligonucleotides |
| US20050197312A1 (en) * | 2004-03-03 | 2005-09-08 | Kevin Fitzgerald | Transcription factor RNA interference reagents and methods of use thereof |
| WO2006116458A2 (en) * | 2005-04-26 | 2006-11-02 | Coley Pharmaceutical Gmbh | Modified oligoribonucleotide analogs with enhances immunostimulatory activity |
-
2006
- 2006-10-12 JP JP2008535031A patent/JP2009511034A/ja active Pending
- 2006-10-12 EA EA200801045A patent/EA200801045A1/ru unknown
- 2006-10-12 BR BRPI0617254-7A patent/BRPI0617254A2/pt not_active IP Right Cessation
- 2006-10-12 CA CA002625488A patent/CA2625488A1/en not_active Abandoned
- 2006-10-12 AU AU2006301230A patent/AU2006301230A1/en not_active Abandoned
- 2006-10-12 KR KR1020087011347A patent/KR20080065656A/ko not_active Ceased
- 2006-10-12 EP EP06807200A patent/EP1937812A2/en not_active Withdrawn
- 2006-10-12 WO PCT/EP2006/067334 patent/WO2007042554A2/en not_active Ceased
- 2006-10-12 US US12/088,752 patent/US20090169472A1/en not_active Abandoned
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