JP2009509956A - 非イオン性界面活性剤を使用して中耳内への経膜的薬物送達を促進する、中耳炎の処置および予防のための方法 - Google Patents
非イオン性界面活性剤を使用して中耳内への経膜的薬物送達を促進する、中耳炎の処置および予防のための方法 Download PDFInfo
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- JP2009509956A JP2009509956A JP2008532243A JP2008532243A JP2009509956A JP 2009509956 A JP2009509956 A JP 2009509956A JP 2008532243 A JP2008532243 A JP 2008532243A JP 2008532243 A JP2008532243 A JP 2008532243A JP 2009509956 A JP2009509956 A JP 2009509956A
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- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 1
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- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72053605P | 2005-09-26 | 2005-09-26 | |
| PCT/US2006/033598 WO2007037886A2 (en) | 2005-09-26 | 2006-08-25 | Methods for treatment and prevention of otitis media using nonionic surfactants to facilitate transmembrane drug delivery into the middle ear |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009509956A true JP2009509956A (ja) | 2009-03-12 |
| JP2009509956A5 JP2009509956A5 (enExample) | 2009-09-03 |
Family
ID=37900209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008532243A Withdrawn JP2009509956A (ja) | 2005-09-26 | 2006-08-25 | 非イオン性界面活性剤を使用して中耳内への経膜的薬物送達を促進する、中耳炎の処置および予防のための方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20080318918A1 (enExample) |
| EP (1) | EP1931388A4 (enExample) |
| JP (1) | JP2009509956A (enExample) |
| CN (1) | CN101272807A (enExample) |
| AU (1) | AU2006295248A1 (enExample) |
| BR (1) | BRPI0616415A2 (enExample) |
| CA (1) | CA2622002A1 (enExample) |
| EA (1) | EA200800950A1 (enExample) |
| IL (1) | IL190079A0 (enExample) |
| WO (1) | WO2007037886A2 (enExample) |
| ZA (1) | ZA200803370B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8271101B2 (en) * | 2007-08-29 | 2012-09-18 | Advanced Bionics | Modular drug delivery system for minimizing trauma during and after insertion of a cochlear lead |
| RU2358743C1 (ru) * | 2008-03-04 | 2009-06-20 | Андрей Валериевич Давыдов | Средство и способ лечения экссудативного среднего отита |
| US11969501B2 (en) | 2008-04-21 | 2024-04-30 | Dompé Farmaceutici S.P.A. | Auris formulations for treating otic diseases and conditions |
| WO2009132050A2 (en) | 2008-04-21 | 2009-10-29 | Otonomy, Inc. | Auris formulations for treating otic diseases and conditions |
| MY161021A (en) | 2008-05-14 | 2017-03-31 | Otonomy Inc | Controlled release corticosteroid and methods for the treatment of otic disorders |
| US8648119B2 (en) | 2008-05-23 | 2014-02-11 | Otonomy, Inc. | Controlled release immunomodulator compositions and methods for the treatment of otic disorders |
| US8846770B2 (en) | 2008-06-18 | 2014-09-30 | Otonomy, Inc. | Controlled release aural pressure modulator compositions and methods for the treatment of OTIC disorders |
| US8349353B2 (en) | 2008-06-27 | 2013-01-08 | Otonomy, Inc. | Controlled release cytotoxic agent compositions and methods for the treatment of otic disorders |
| WO2010011466A2 (en) | 2008-06-27 | 2010-01-28 | Otonomy, Inc. | Controlled-release cns modulating compositions and methods for the treatment of otic disorders |
| US8399018B2 (en) | 2008-07-21 | 2013-03-19 | Otonomy, Inc. | Controlled release ion channel modulator compositions and methods for the treatment of otic disorders |
| US8318817B2 (en) | 2008-07-21 | 2012-11-27 | Otonomy, Inc. | Controlled release antimicrobial compositions and methods for the treatment of otic disorders |
| US8496957B2 (en) | 2008-07-21 | 2013-07-30 | Otonomy, Inc | Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders |
| US8784870B2 (en) | 2008-07-21 | 2014-07-22 | Otonomy, Inc. | Controlled release compositions for modulating free-radical induced damage and methods of use thereof |
| WO2010011605A2 (en) | 2008-07-21 | 2010-01-28 | Otonomy, Inc. | Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders |
| US20100016450A1 (en) * | 2008-07-21 | 2010-01-21 | Otonomy, Inc. | Controlled release delivery devices for the treatment of otic disorders |
| US11033624B2 (en) | 2010-06-02 | 2021-06-15 | Novaflux Inc. | Medical item for prevention and treatment of ear infection |
| MD674Z (ro) * | 2013-03-07 | 2014-04-30 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Metodă de tratament al otitei medii exudative la copii |
| US10166146B2 (en) | 2013-03-08 | 2019-01-01 | Mark Mitchnick | Ear medication dispenser with sensor |
| CN105682742A (zh) | 2013-08-27 | 2016-06-15 | 奥德纳米有限公司 | 小儿耳部病症的治疗 |
| WO2015168642A1 (en) | 2014-05-02 | 2015-11-05 | Labib Mohamed E | Drug-releasing device usable in mucosal body cavities |
| EP3512513A4 (en) | 2016-09-16 | 2020-04-15 | Otonomy, Inc. | OTIC GEL FORMULATIONS FOR THE TREATMENT OF EXTERNAL OTITIS |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3549770A (en) * | 1963-12-09 | 1970-12-22 | Crown Zellerbach Corp | Therapeutic administration of effective amounts of dimethyl sulfoxide to human and animal subjects |
| US5231112A (en) * | 1984-04-12 | 1993-07-27 | The Liposome Company, Inc. | Compositions containing tris salt of cholesterol hemisuccinate and antifungal |
| US4761288A (en) * | 1984-09-24 | 1988-08-02 | Mezei Associates Limited | Multiphase liposomal drug delivery system |
| US4897269A (en) * | 1984-09-24 | 1990-01-30 | Mezei Associates Limited | Administration of drugs with multiphase liposomal delivery system |
| DE3936328A1 (de) * | 1989-10-27 | 1991-05-02 | Schering Ag | Pharmazeutische praeparate |
| US5542935A (en) * | 1989-12-22 | 1996-08-06 | Imarx Pharmaceutical Corp. | Therapeutic delivery systems related applications |
| US5540930A (en) * | 1993-10-25 | 1996-07-30 | Pharmos Corporation | Suspension of loteprednol etabonate for ear, eye, or nose treatment |
| US5843930A (en) * | 1995-06-06 | 1998-12-01 | Bayer Corporation | Method of treating otitis with ciprofloxacin-hydrocortisone suspension |
| US6716830B2 (en) * | 1998-09-30 | 2004-04-06 | Alcon, Inc. | Ophthalmic antibiotic compositions containing moxifloxacin |
| US6093417A (en) * | 1999-01-11 | 2000-07-25 | Advanced Medical Instruments | Composition to treat ear disorders |
| US6723714B2 (en) * | 1999-07-06 | 2004-04-20 | Blansett Pharmacal Co., Inc. | Aqueous solvent for corticosteroids |
| WO2001015677A2 (en) * | 1999-08-31 | 2001-03-08 | Alcon Laboratories, Inc. | Use of 5-ht1b/1d agonists to treat otic pain |
| HUP0303696A3 (en) * | 2000-09-25 | 2005-05-30 | Bayer Healthcare Llc Tarrytown | Otic microbial combinations for treatment of animals with ruptured tympanic membrane |
| US6716813B2 (en) * | 2000-11-28 | 2004-04-06 | House Ear Institute | Use of antimicrobial proteins and peptides for the treatment of otitis media and paranasal sinusitis |
| US7220431B2 (en) * | 2002-11-27 | 2007-05-22 | Regents Of The University Of Minnesota | Methods and compositions for applying pharmacologic agents to the ear |
| WO2004052236A2 (en) * | 2002-12-06 | 2004-06-24 | Arriva Pharmaceuticals, Inc. | Methods and compositions for treatment of otitis media |
| LT1610613T (lt) * | 2003-04-04 | 2017-03-27 | Merial, Inc. | Vietinio taikymo antihelmintinės veterinarinės kompozicijos |
| US20050058673A1 (en) * | 2003-09-09 | 2005-03-17 | 3M Innovative Properties Company | Antimicrobial compositions and methods |
| US20080124385A1 (en) * | 2004-09-03 | 2008-05-29 | Piedmont Pharmaceuticals,Llc. | Methods for Transmembrane Treatment and Prevention of Otitis Media |
| US20060051384A1 (en) * | 2004-09-07 | 2006-03-09 | 3M Innovative Properties Company | Antiseptic compositions and methods of use |
-
2006
- 2006-08-25 CN CNA2006800353863A patent/CN101272807A/zh active Pending
- 2006-08-25 US US12/066,488 patent/US20080318918A1/en not_active Abandoned
- 2006-08-25 JP JP2008532243A patent/JP2009509956A/ja not_active Withdrawn
- 2006-08-25 EA EA200800950A patent/EA200800950A1/ru unknown
- 2006-08-25 AU AU2006295248A patent/AU2006295248A1/en not_active Abandoned
- 2006-08-25 BR BRPI0616415-3A patent/BRPI0616415A2/pt not_active IP Right Cessation
- 2006-08-25 WO PCT/US2006/033598 patent/WO2007037886A2/en not_active Ceased
- 2006-08-25 CA CA002622002A patent/CA2622002A1/en not_active Abandoned
- 2006-08-25 EP EP06813877A patent/EP1931388A4/en not_active Withdrawn
- 2006-08-25 ZA ZA200803370A patent/ZA200803370B/xx unknown
-
2008
- 2008-03-11 IL IL190079A patent/IL190079A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200803370B (en) | 2009-09-30 |
| WO2007037886A3 (en) | 2007-10-25 |
| CA2622002A1 (en) | 2007-04-05 |
| IL190079A0 (en) | 2008-08-07 |
| BRPI0616415A2 (pt) | 2011-06-21 |
| EA200800950A1 (ru) | 2008-08-29 |
| WO2007037886A2 (en) | 2007-04-05 |
| CN101272807A (zh) | 2008-09-24 |
| AU2006295248A1 (en) | 2007-04-05 |
| EP1931388A2 (en) | 2008-06-18 |
| US20080318918A1 (en) | 2008-12-25 |
| EP1931388A4 (en) | 2010-12-15 |
| WO2007037886B1 (en) | 2008-01-10 |
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