JP2009509928A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009509928A5 JP2009509928A5 JP2008529292A JP2008529292A JP2009509928A5 JP 2009509928 A5 JP2009509928 A5 JP 2009509928A5 JP 2008529292 A JP2008529292 A JP 2008529292A JP 2008529292 A JP2008529292 A JP 2008529292A JP 2009509928 A5 JP2009509928 A5 JP 2009509928A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- phenyl
- halogen
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71332305P | 2005-09-01 | 2005-09-01 | |
| PCT/US2006/034128 WO2007027959A1 (en) | 2005-09-01 | 2006-08-30 | Novel benzopyran derivatives as potassium channel openers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009509928A JP2009509928A (ja) | 2009-03-12 |
| JP2009509928A5 true JP2009509928A5 (https=) | 2009-10-01 |
Family
ID=37401455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008529292A Pending JP2009509928A (ja) | 2005-09-01 | 2006-08-30 | カリウムチャンネル開口剤としての新規ベンゾピラン誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7838553B2 (https=) |
| EP (1) | EP1937669B9 (https=) |
| JP (1) | JP2009509928A (https=) |
| CN (1) | CN101296925A (https=) |
| AT (1) | ATE543813T1 (https=) |
| AU (1) | AU2006284675A1 (https=) |
| CA (1) | CA2620894A1 (https=) |
| DK (1) | DK1937669T3 (https=) |
| ES (1) | ES2379098T3 (https=) |
| PL (1) | PL1937669T3 (https=) |
| PT (1) | PT1937669E (https=) |
| SI (1) | SI1937669T1 (https=) |
| WO (1) | WO2007027959A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007027780A2 (en) * | 2005-09-01 | 2007-03-08 | Janssen Pharmaceutica N.V. | Benzopyran and pyranopyridine derivatives as potassium channel openers |
| CA2816753A1 (en) | 2010-11-08 | 2012-05-18 | Lycera Corporation | N- sulfonylated tetrahydroquinolines and related bicyclic compounds inhibition of rory activity and the treatment of diseases |
| AU2013259737A1 (en) | 2012-05-08 | 2014-10-02 | Lycera Corporation | Tetrahydronaphthyridine and related bicyclic compounds for inhibition of RORgamma activity and the treatment of disease |
| JP6242868B2 (ja) | 2012-05-08 | 2017-12-06 | リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ | ＲＯＲγのアゴニストとしての使用のためおよび疾患の処置のためのテトラヒドロ［１，８］ナフチリジンスルホンアミドおよび関連化合物 |
| MX363350B (es) | 2012-05-08 | 2019-03-20 | Merck Sharp & Dohme | COMPUESTOS DE SULFONA BICÍCLICA PARA LA INHIBICIÓN DE LA ACTIVIDAD RORgamma Y EL TRATAMIENTO DE ENFERMEDADES. |
| US9663502B2 (en) | 2013-12-20 | 2017-05-30 | Lycera Corporation | 2-Acylamidomethyl and sulfonylamidomethyl benzoxazine carbamates for inhibition of RORgamma activity and the treatment of disease |
| WO2015095795A1 (en) | 2013-12-20 | 2015-06-25 | Merck Sharp & Dohme Corp. | TETRAHYDRONAPHTHYRIDINE, BENZOXAZINE, AZA-BENZOXAZINE, AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF RORgamma ACTIVITY AND THE TREATMENT OF DISEASE |
| US9783511B2 (en) | 2013-12-20 | 2017-10-10 | Lycera Corporation | Carbamate benzoxazine propionic acids and acid derivatives for modulation of RORgamma activity and the treatment of disease |
| JP2017507950A (ja) | 2014-02-27 | 2017-03-23 | リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ | レチノイン酸受容体関連オーファン受容体ガンマのアゴニストを使用する養子細胞療法及び関連治療方法 |
| US9896441B2 (en) | 2014-05-05 | 2018-02-20 | Lycera Corporation | Tetrahydroquinoline sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease |
| JP6523337B2 (ja) | 2014-05-05 | 2019-05-29 | リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ | ＲＯＲγのアゴニストとしての使用及び疾患治療のためのベンゼンスルホンアミド及び関連化合物 |
| EP3256450B1 (en) | 2015-02-11 | 2020-12-02 | Merck Sharp & Dohme Corp. | Substituted pyrazole compounds as ror-gamma-t inhibitors and uses thereof |
| JP2018515491A (ja) | 2015-05-05 | 2018-06-14 | リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ | ＲＯＲγの作動薬及び疾患の療法として使用するジヒドロ−２Ｈ−ベンゾ［ｂ］［１，４］オキサジンスルホンアミド及び関連化合物 |
| KR20180025894A (ko) | 2015-06-11 | 2018-03-09 | 라이세라 코퍼레이션 | Rory의 작용제로서 사용하기 위한 아릴 디히드로-2h-벤조[b][1,4]옥사진 술폰아미드 및 관련 화합물 및 질환의 치료 |
| WO2017075178A1 (en) | 2015-10-27 | 2017-05-04 | Merck Sharp & Dohme Corp. | SUBSTITUTED BICYCLIC PYRAZOLE COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF |
| AU2016344118A1 (en) | 2015-10-27 | 2018-05-10 | Merck Sharp & Dohme Corp. | Heteroaryl substituted benzoic acids as rorgammat inhibitors and uses thereof |
| RU2018117503A (ru) | 2015-10-27 | 2019-11-28 | Мерк Шарп И Доум Корп. | ЗАМЕЩЕННЫЕ ИНДАЗОЛЬНЫЕ СОЕДИНЕНИЯ В КАЧЕСТВЕ ИНГИБИТОРОВ RORγТ И ИХ ПРИМЕНЕНИЕ |
| CN116535379B (zh) * | 2023-06-29 | 2023-09-19 | 希格生科（深圳）有限公司 | 化合物及其医药用途 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH594675A5 (https=) * | 1976-01-30 | 1978-01-13 | Ciba Geigy Ag | |
| EP0172352B1 (en) | 1984-06-22 | 1990-08-29 | Beecham Group Plc | Active benzopyran compounds |
| DE3682331D1 (de) | 1985-06-08 | 1991-12-12 | Beecham Group Plc | Pyrano(3,2-c)pyridinderivate, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen. |
| DE3669317D1 (de) | 1985-09-11 | 1990-04-12 | Beecham Group Plc | Chromanderivate und aehnliche verbindungen mit blutdrucksenkender wirkung. |
| DE3726261A1 (de) | 1986-12-23 | 1988-07-07 | Merck Patent Gmbh | Chromanderivate |
| US5387587A (en) | 1986-12-23 | 1995-02-07 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Chroman derivatives |
| US5284838A (en) * | 1987-06-23 | 1994-02-08 | Elf Sanofi | Use of 2,2-dimethylchroman-3-ol derivatives in the treatment of asthma |
| US4971982A (en) | 1987-07-06 | 1990-11-20 | Hoffmann-La Roche Inc. | Benzopyran derivatives |
| DE3732146A1 (de) | 1987-09-24 | 1989-04-06 | Merck Patent Gmbh | Azachromanderivate |
| US5254557A (en) * | 1988-05-09 | 1993-10-19 | Beecham Group P.L.C. | Compound and treatment |
| DE3823533A1 (de) * | 1988-07-12 | 1990-02-08 | Beiersdorf Ag | Substituierte 4-heterocyclyl-2h-benzo(b)pyrane, verfahren und 4-hydroxy-3-brom-, 3,4-oxiranyl-3,4-dehydro-2h-benzo(b)pyrane als zwischenprodukte zu ihrer herstellung, sowie sie enthaltende pharmazeutsche praeparate |
| EP0376524B1 (en) * | 1988-12-13 | 1995-03-29 | Beecham Group Plc | Benzopyran and related compounds |
| US5104890A (en) * | 1989-03-28 | 1992-04-14 | Fujisawa Pharmaceutical Company, Ltd. | Benzopyran derivatives and processes for preparation thereof |
| DE3922392A1 (de) * | 1989-07-07 | 1991-01-17 | Merck Patent Gmbh | Chromanderivate |
| GB8916683D0 (en) | 1989-07-21 | 1989-09-06 | Beecham Group Plc | Novel compounds |
| US4983612A (en) * | 1989-10-05 | 1991-01-08 | American Home Products Corporation | Antihypertensive benzopyran derivatives |
| US5254555A (en) * | 1989-10-30 | 1993-10-19 | Beecham Group P.L.C. | Amino pyrimidin-7-yl substituted benzopyrans for treatment of hypertension |
| US5171857A (en) * | 1990-03-29 | 1992-12-15 | American Home Products Corporation | Antihypertensive benzopyran derivatives |
| GB2242628A (en) | 1990-04-06 | 1991-10-09 | Sandoz Ltd | Asthma prophylactic use of K+ channel activators |
| US5254578A (en) * | 1990-10-24 | 1993-10-19 | Sankyo Company, Limited | Benzopyran derivatives having anti-hypertensive and vasodilatory activity and their therapeutic use |
| US5310932A (en) * | 1991-04-15 | 1994-05-10 | E. R. Squibb & Sons, Inc. | Chromanyl substituted indole potassium channel openers |
| US5225566A (en) | 1992-05-08 | 1993-07-06 | American Home Products Corporation | Indazolanonyl derivative of benzopyran |
| US5206252A (en) * | 1992-05-08 | 1993-04-27 | American Home Products Corporation | Thiadiazolyl-amino derivatives of benzopyrans and indanes |
| US5236935A (en) * | 1992-05-21 | 1993-08-17 | Korea Research Institute Of Chemical Technology | Benzopyran derivatives and processes for the preparation thereof |
| US5837702A (en) * | 1993-10-07 | 1998-11-17 | Bristol-Myers Squibb Co. | 4-arylamino-benzopyran and related compounds |
| US6253627B1 (en) * | 2000-06-12 | 2001-07-03 | The United States Of America As Represented By The Secretary Of The Navy | Thin-line towed-array force measurement apparatus and method |
| CN101921279A (zh) | 2003-10-01 | 2010-12-22 | 阿得罗公司 | 螺环杂环衍生物及其应用方法 |
| WO2007027780A2 (en) * | 2005-09-01 | 2007-03-08 | Janssen Pharmaceutica N.V. | Benzopyran and pyranopyridine derivatives as potassium channel openers |
-
2006
- 2006-08-30 JP JP2008529292A patent/JP2009509928A/ja active Pending
- 2006-08-30 AU AU2006284675A patent/AU2006284675A1/en not_active Abandoned
- 2006-08-30 ES ES06802751T patent/ES2379098T3/es active Active
- 2006-08-30 SI SI200631308T patent/SI1937669T1/sl unknown
- 2006-08-30 PT PT06802751T patent/PT1937669E/pt unknown
- 2006-08-30 CN CNA2006800402874A patent/CN101296925A/zh active Pending
- 2006-08-30 US US11/468,325 patent/US7838553B2/en not_active Expired - Fee Related
- 2006-08-30 DK DK06802751.5T patent/DK1937669T3/da active
- 2006-08-30 EP EP06802751A patent/EP1937669B9/en active Active
- 2006-08-30 PL PL06802751T patent/PL1937669T3/pl unknown
- 2006-08-30 WO PCT/US2006/034128 patent/WO2007027959A1/en not_active Ceased
- 2006-08-30 AT AT06802751T patent/ATE543813T1/de active
- 2006-08-30 CA CA002620894A patent/CA2620894A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009509928A5 (https=) | ||
| WO2004074270A3 (en) | Inhibitors of hepatitis c virus rna-dependent rna polymerase, and compositions and treatments using the same | |
| JP2016506960A5 (https=) | ||
| JP2009538897A5 (https=) | ||
| RU2007119562A (ru) | Тетрациклические производные индолов в качестве противовирусных агентов | |
| RU2011116227A (ru) | Пиразолопиридиновые производные как ингибиторы надфн-оксидазы | |
| JP2008526999A5 (https=) | ||
| CA2492723A1 (en) | Novel 2,5-disubstituted pyrimidine derivatives | |
| RU2016108987A (ru) | Замещенные бензоазепины в качестве модуляторов toll-подобного рецептора | |
| JP2011509309A5 (https=) | ||
| CA2628131A1 (en) | Hydroxy and alkoxy substituted 1h-imidazoquinolines and methods | |
| ES2437346T3 (es) | Procedimiento para la producción de derivado de diamina | |
| WO2008147557A3 (en) | Heteroaryl substituted thiazoles and their use as antiviral agents | |
| RU2014121205A (ru) | Производные азолов | |
| CA2564629A1 (en) | Substituted phenylaminopyrimidines | |
| JP2006502119A5 (https=) | ||
| JP2013508382A5 (https=) | ||
| RU2009123525A (ru) | ПРОИЗВОДНЫЕ 5-СУЛЬФАНИЛМЕТИЛ[1,2,4}ТРИАЗОЛ[1,5-а]ПИРИМИДИН-7-ОЛА В КАЧЕСТВЕ АНТАГОНИСТОВ CXCR2 | |
| CA2728098A1 (en) | Pyrazole-containing tricyclic compounds as_antagonits of an ep1 receptor | |
| JP2015535834A5 (https=) | ||
| JP2006511446A5 (https=) | ||
| JP2005538111A5 (https=) | ||
| RU2435760C2 (ru) | 1н-хиназолин-2,4-дионы | |
| RU2011112684A (ru) | АГЕНТ, СПОСОБСТВУЮЩИЙ РОСТУ ВОЛОС, СОДЕРЖАЩИЙ В КАЧЕСТВЕ АКТИВНОГО ИНГРЕДИЕНТА ПРОИЗВОДНОЕ 15,15-ДИФТОРПРОСТАГЛАНДИНА F2α | |
| WO2007120726B1 (en) | Compositions and methods related to rad51 inactivation in the treatment of neoplastic diseases, and especially cml |