JP2009508960A - ＡＰＯＥ４陰性患者における認識機能の改善のためのＰＰＡＲγアゴニスト - Google Patents
ＡＰＯＥ４陰性患者における認識機能の改善のためのＰＰＡＲγアゴニスト Download PDFInfo
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- JP2009508960A JP2009508960A JP2008532341A JP2008532341A JP2009508960A JP 2009508960 A JP2009508960 A JP 2009508960A JP 2008532341 A JP2008532341 A JP 2008532341A JP 2008532341 A JP2008532341 A JP 2008532341A JP 2009508960 A JP2009508960 A JP 2009508960A
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
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- A—HUMAN NECESSITIES
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- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
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Applications Claiming Priority (3)
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| US71935305P | 2005-09-22 | 2005-09-22 | |
| US72737705P | 2005-10-17 | 2005-10-17 | |
| PCT/US2006/036603 WO2007038115A2 (en) | 2005-09-22 | 2006-09-20 | Ppar-gamma agonists for improvement of cognitive function in apoe4 negative patients |
Publications (2)
| Publication Number | Publication Date |
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| JP2009508960A true JP2009508960A (ja) | 2009-03-05 |
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| JP2008532341A Pending JP2009508960A (ja) | 2005-09-22 | 2006-09-20 | ＡＰＯＥ４陰性患者における認識機能の改善のためのＰＰＡＲγアゴニスト |
| JP2008532338A Pending JP2009508959A (ja) | 2005-09-22 | 2006-09-20 | 認識機能の改善のためのロシグリタゾンおよびドネペジルの組合せ |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019529524A (ja) * | 2016-07-26 | 2019-10-17 | オージオ・ファーマシューティカルズ，リミテッド・ライアビリティ・カンパニー | Ｓ−エコールを用いてアルツハイマー病を診断するおよび治療する方法 |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2066355A2 (en) * | 2006-09-19 | 2009-06-10 | Braincells, Inc. | Combination comprising a peroxisome proliferator activated receptor agent and a second neurogenic agent for treating a nervous system disorder, increasing neurodifferentiation and increasing neurogenesis |
| IL187159A0 (en) | 2007-07-03 | 2009-02-11 | Gur Megiddo | Use of metadoxine in relief of alcohol intoxication |
| WO2009043593A1 (en) * | 2007-10-05 | 2009-04-09 | Merz Pharma Gmbh & Co. Kgaa | Combination therapy using memantine and glitazones |
| EP2085120A1 (en) * | 2008-02-01 | 2009-08-05 | Merz Pharma GmbH & Co. KGaA | The use of substances for the treatment of central or peripheral insulin receptor impairment and insulin resistance |
| KR20160127181A (ko) | 2008-08-12 | 2016-11-02 | 진판델 파마슈티컬스 인코포레이티드 | 질환 위험 인자의 식별 방법 |
| US8846315B2 (en) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
| US20100152249A1 (en) * | 2008-12-11 | 2010-06-17 | Board Of Trustees Of The Leland Stanford Junior University | Compositons and method for treatment of mood and cognitive impairments |
| NZ597319A (en) * | 2009-06-25 | 2014-06-27 | Alcobra Ltd | A method for the treatment, alleviation of symptoms of, relieving, improving and preventing a cognitive disease, disorder or condition |
| US20100178307A1 (en) * | 2010-01-13 | 2010-07-15 | Jianye Wen | Transdermal anti-dementia active agent formulations and methods for using the same |
| WO2012053016A1 (en) * | 2010-10-22 | 2012-04-26 | Cadila Healthcare Limited | Sustained release pharmaceutical compositions of donepezil |
| CN107362165A (zh) | 2011-01-10 | 2017-11-21 | 金帆德尔制药股份有限公司 | 用于治疗阿尔茨海默病的方法和药物产品 |
| BR112013017444A2 (pt) * | 2011-01-10 | 2016-09-27 | Zinfandel Pharmaceuticals Inc | método de determinar o risco para o desenvolvimento da doença de alzheimer em um indivíduo, de tratar um indivíduo para a doença de alzheimer e de determinar um risco para desenvolver a doença de alzheimer em um paciente |
| AP2014007645A0 (en) | 2011-10-21 | 2014-05-31 | Takeda Pharmaceutical | Sustained-release preparation |
| CA2853100A1 (en) * | 2011-10-24 | 2013-05-02 | Intellect Neurosciences, Inc. | Compositions and methods for treatment of proteinopathies |
| US20160113913A1 (en) * | 2013-04-19 | 2016-04-28 | Takeda Pharmaceutical Company Limited | Controlled-release drug formulation |
| US20180153859A1 (en) * | 2016-12-02 | 2018-06-07 | T3D Therapeutics, Inc. | Methods of treating or preventing cognitive impairment using indane acetic acid derivatives based on apoe4 genotype |
| KR102142026B1 (ko) * | 2017-05-31 | 2020-08-06 | 주식회사 대웅제약 | 방출제어가 용이한 서방성 약물 미립자의 제조방법 |
| KR102224917B1 (ko) | 2018-03-20 | 2021-03-09 | (주)인벤티지랩 | 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물의 제조 방법 및 이의 제조 방법으로 제조된 인지 장애 관련 질병의 예방 또는 치료용 약학적 조성물 |
| US12303604B1 (en) | 2024-10-16 | 2025-05-20 | Currax Pharmaceuticals Llc | Pharmaceutical formulations comprising naltrexone and/or bupropion |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2142300C (en) * | 1992-10-13 | 2005-08-23 | Allen D. Roses | Methods for detecting alzheimer's disease |
| US6191154B1 (en) * | 1998-11-27 | 2001-02-20 | Case Western Reserve University | Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases |
| ATE476978T1 (de) * | 1998-12-17 | 2010-08-15 | Mindset Biopharmaceuticals Usa | Verbesserung der geistigen fähigkeiten durch die steigerung der insulin-empfindlichkeit des gehirns |
| WO2005074917A1 (en) * | 2004-01-30 | 2005-08-18 | Axonyx, Inc. | Methods for treatment of complications of diabetes |
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2006
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019529524A (ja) * | 2016-07-26 | 2019-10-17 | オージオ・ファーマシューティカルズ，リミテッド・ライアビリティ・カンパニー | Ｓ−エコールを用いてアルツハイマー病を診断するおよび治療する方法 |
Also Published As
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| CR9849A (es) | 2008-05-21 |
| CR9848A (es) | 2008-06-18 |
| MA29872B1 (fr) | 2008-10-03 |
| PE20070618A1 (es) | 2007-07-04 |
| AR056527A1 (es) | 2007-10-10 |
| US20080262047A1 (en) | 2008-10-23 |
| MA29871B1 (fr) | 2008-10-03 |
| IL190224A0 (en) | 2008-11-03 |
| WO2007038115A2 (en) | 2007-04-05 |
| WO2007038112A3 (en) | 2007-12-06 |
| IL190217A0 (en) | 2008-11-03 |
| CA2623204A1 (en) | 2007-04-05 |
| EA200800879A1 (ru) | 2008-10-30 |
| KR20080056731A (ko) | 2008-06-23 |
| KR20080058413A (ko) | 2008-06-25 |
| TW200803896A (en) | 2008-01-16 |
| BRPI0616192A2 (pt) | 2011-06-14 |
| NO20081843L (no) | 2008-06-16 |
| TW200803851A (en) | 2008-01-16 |
| AR055649A1 (es) | 2007-08-29 |
| AU2006295007A1 (en) | 2007-04-05 |
| EP1926488A2 (en) | 2008-06-04 |
| PE20070976A1 (es) | 2007-12-05 |
| EA200800880A1 (ru) | 2009-02-27 |
| AU2006295010A1 (en) | 2007-04-05 |
| BRPI0616100A2 (pt) | 2011-06-07 |
| WO2007038112A2 (en) | 2007-04-05 |
| NO20081847L (no) | 2008-06-18 |
| EP1940403A2 (en) | 2008-07-09 |
| WO2007038115A3 (en) | 2007-12-13 |
| US20080226719A1 (en) | 2008-09-18 |
| JP2009508959A (ja) | 2009-03-05 |
| CA2623210A1 (en) | 2007-04-05 |
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