JP2009508916A - Ｎｓａｉｄとパラセタモールを含んだ組成物 - Google Patents

Ｎｓａｉｄとパラセタモールを含んだ組成物 Download PDF

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Publication number
JP2009508916A
JP2009508916A JP2008531764A JP2008531764A JP2009508916A JP 2009508916 A JP2009508916 A JP 2009508916A JP 2008531764 A JP2008531764 A JP 2008531764A JP 2008531764 A JP2008531764 A JP 2008531764A JP 2009508916 A JP2009508916 A JP 2009508916A
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JP
Japan
Prior art keywords
paracetamol
nsaid
solidified melt
melt particles
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008531764A
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English (en)
Japanese (ja)
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JP2009508916A5 (enExample
Inventor
ロバート シェリー
Original Assignee
レキット ベンキサー ヘルスケア （ユーケイ） リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35335274&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP2009508916(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by レキット ベンキサー ヘルスケア （ユーケイ） リミテッド filed Critical レキット ベンキサー ヘルスケア （ユーケイ） リミテッド
Publication of JP2009508916A publication Critical patent/JP2009508916A/ja
Publication of JP2009508916A5 publication Critical patent/JP2009508916A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/67—Phosphorus compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2008531764A 2005-09-22 2006-09-07 Ｎｓａｉｄとパラセタモールを含んだ組成物 Pending JP2009508916A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0519350.3A GB0519350D0 (en) 2005-09-22 2005-09-22 Therapeutic agents
PCT/GB2006/003297 WO2007034135A1 (en) 2005-09-22 2006-09-07 Composition comprising a nsaid and paracetamol

Publications (2)

Publication Number Publication Date
JP2009508916A true JP2009508916A (ja) 2009-03-05
JP2009508916A5 JP2009508916A5 (enExample) 2009-10-22

Family

ID=35335274

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008531764A Pending JP2009508916A (ja) 2005-09-22 2006-09-07 Ｎｓａｉｄとパラセタモールを含んだ組成物

Country Status (13)

Country Link
US (1) US20090142392A1 (enExample)
EP (2) EP2851068B1 (enExample)
JP (1) JP2009508916A (enExample)
KR (2) KR20130141728A (enExample)
CN (1) CN101267807B (enExample)
AU (1) AU2006293798B2 (enExample)
CA (1) CA2623281A1 (enExample)
GB (1) GB0519350D0 (enExample)
PL (2) PL1926477T3 (enExample)
RU (1) RU2438656C2 (enExample)
SG (1) SG149080A1 (enExample)
WO (1) WO2007034135A1 (enExample)
ZA (1) ZA200802436B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022540348A (ja) * 2019-06-27 2022-09-15 グラクソスミスクライン・コンシューマー・ヘルスケア・ホールディングス・ユーエス・リミテッド・ライアビリティ・カンパニー 新規なイブプロフェン及びアセトアミノフェン組成物

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080275125A1 (en) 2004-07-07 2008-11-06 Aft Pharmaceuticals Limited Combination Composition
GB2447898B (en) * 2007-03-24 2011-08-17 Reckitt Benckiser Healthcare A tablet having improved stability with at least two actives
KR20100134557A (ko) * 2008-01-11 2010-12-23 씨아이피엘에이 엘티디. 고체 약제학적 투여 제형
WO2009128543A1 (ja) * 2008-04-17 2009-10-22 ニプロ株式会社 シリカを含む錠剤の製造方法、錠剤及び錠剤用複合粒子
AU2009304002B9 (en) * 2008-10-14 2014-06-26 Aft Pharmaceuticals Limited A medicinal product and treatment
ES2365961B1 (es) * 2010-03-30 2013-01-24 Farmasierra Manufacturing S.L. Formulación farmacéutica a base de ibuprofeno y codeína de estabilidad mejorada.
CN105816434B (zh) * 2016-04-19 2019-09-17 山东新华制药股份有限公司 布洛芬颗粒及其制备方法
EP3700509B1 (en) 2017-11-29 2023-11-22 Ilko Ilaç Sanayi Ve Ticaret Anonim Sirketi Color stable fixed dose tablet combination of ibuprofen and paracetamol
US20190350883A1 (en) * 2018-05-20 2019-11-21 Luan Chau Pharmaceutical Composition of Acetaminophen/Ibuprofen
US11197830B2 (en) 2019-02-27 2021-12-14 Aft Pharmaceuticals Limited Pharmaceutical composition containing acetaminophen and ibuprofen
US11779541B2 (en) 2019-03-26 2023-10-10 Johnson & Johnson Consumer Inc. Immediate release dosage form
CN110372713B (zh) * 2019-08-15 2022-05-17 广州市汉普医药有限公司 一种普拉洛芬的精制纯化方法
WO2023281089A2 (en) 2021-07-08 2023-01-12 Krka, D.D., Novo Mesto Pharmaceutical composition comprising naproxen and paracetamol

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05148139A (ja) * 1991-11-29 1993-06-15 Lion Corp イブプロフエン含有解熱鎮痛剤
JPH11158066A (ja) * 1997-11-28 1999-06-15 Grelan Pharmaceut Co Ltd イブプロフェン含有医薬製剤
JP2003516341A (ja) * 1999-12-09 2003-05-13 ザ ブーツ カンパニー ピーエルシー 治療薬
US6787157B1 (en) * 1998-03-10 2004-09-07 Abbott Laboratories Multiphase active ingredient-containing formulations
JP2005503355A (ja) * 2001-06-07 2005-02-03 ザ ブーツ カンパニー ピーエルシー 治療薬

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5271811A (en) * 1988-01-29 1993-12-21 Hoechst Celanese Corporation Process for purifying 2-(4-isobutylphenyl)-propionic acid by vacuum distillation
DE3802619C1 (enExample) 1988-01-29 1989-09-07 Hoechst Ag, 6230 Frankfurt, De
DE3833448A1 (de) 1988-10-01 1990-04-12 Hoechst Ag Verfahren zur gewinnung von ibuprofen fuer die direkttablettierung
US5409709A (en) * 1991-11-29 1995-04-25 Lion Corporation Antipyretic analgesic preparation containing ibuprofen
DE4418837A1 (de) * 1994-05-30 1995-12-07 Bayer Ag Thermisches Granulierverfahren
DE4446468A1 (de) * 1994-12-23 1996-06-27 Basf Ag Verfahren zur Herstellung von umhüllten Tabletten
RU2192248C2 (ru) * 1998-07-13 2002-11-10 Товарищество с ограниченной ответственностью фирма "Эйкос" Препарат "антигриппин"
RU2237470C1 (ru) * 2003-01-27 2004-10-10 Купсин Евгений Вениаминович Комбинированный препарат для устранения симптомов простудных заболеваний и гриппа (варианты)
US20040265378A1 (en) * 2003-06-25 2004-12-30 Yingxu Peng Method and compositions for producing granules containing high concentrations of biologically active substances
JP2008509206A (ja) * 2004-08-12 2008-03-27 レキット ベンキーザー ヘルスケア （ユーケイ） リミテッド 溶融押出しにより作製するｎｓａｉｄ及び糖アルコールを含む顆粒
GB0423103D0 (en) * 2004-10-19 2004-11-17 Boots Healthcare Int Ltd Therapeutic agents

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05148139A (ja) * 1991-11-29 1993-06-15 Lion Corp イブプロフエン含有解熱鎮痛剤
JPH11158066A (ja) * 1997-11-28 1999-06-15 Grelan Pharmaceut Co Ltd イブプロフェン含有医薬製剤
US6787157B1 (en) * 1998-03-10 2004-09-07 Abbott Laboratories Multiphase active ingredient-containing formulations
JP2003516341A (ja) * 1999-12-09 2003-05-13 ザ ブーツ カンパニー ピーエルシー 治療薬
JP2005503355A (ja) * 2001-06-07 2005-02-03 ザ ブーツ カンパニー ピーエルシー 治療薬

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022540348A (ja) * 2019-06-27 2022-09-15 グラクソスミスクライン・コンシューマー・ヘルスケア・ホールディングス・ユーエス・リミテッド・ライアビリティ・カンパニー 新規なイブプロフェン及びアセトアミノフェン組成物
JP7703220B2 (ja) 2019-06-27 2025-07-07 ヘイリオン ユーエス ホールディングス エルエルシー 新規なイブプロフェン及びアセトアミノフェン組成物

Also Published As

Publication number Publication date
PL2851068T3 (pl) 2020-04-30
KR20080047437A (ko) 2008-05-28
AU2006293798B2 (en) 2012-08-16
EP2851068A3 (en) 2015-05-27
EP2851068B1 (en) 2019-10-23
EP1926477B1 (en) 2017-04-19
EP2851068A2 (en) 2015-03-25
RU2008115507A (ru) 2009-10-27
RU2438656C2 (ru) 2012-01-10
SG149080A1 (en) 2009-01-29
KR20130141728A (ko) 2013-12-26
WO2007034135A1 (en) 2007-03-29
US20090142392A1 (en) 2009-06-04
KR101434906B1 (ko) 2014-08-27
ZA200802436B (en) 2009-07-29
CN101267807B (zh) 2013-04-10
CN101267807A (zh) 2008-09-17
EP1926477A1 (en) 2008-06-04
AU2006293798A1 (en) 2007-03-29
CA2623281A1 (en) 2007-03-29
GB0519350D0 (en) 2005-11-02
PL1926477T3 (pl) 2017-09-29

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