JP2009508476A5 - - Google Patents

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Publication number
JP2009508476A5
JP2009508476A5 JP2008529350A JP2008529350A JP2009508476A5 JP 2009508476 A5 JP2009508476 A5 JP 2009508476A5 JP 2008529350 A JP2008529350 A JP 2008529350A JP 2008529350 A JP2008529350 A JP 2008529350A JP 2009508476 A5 JP2009508476 A5 JP 2009508476A5
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JP
Japan
Prior art keywords
cell line
antibody
polypeptide
produced
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008529350A
Other languages
English (en)
Japanese (ja)
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JP2009508476A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/034382 external-priority patent/WO2007028106A2/en
Publication of JP2009508476A publication Critical patent/JP2009508476A/ja
Publication of JP2009508476A5 publication Critical patent/JP2009508476A5/ja
Pending legal-status Critical Current

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JP2008529350A 2005-08-31 2006-08-31 高められたエフェクター機能をもつ抗体定常領域の製造用の宿主細胞株 Pending JP2009508476A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71305505P 2005-08-31 2005-08-31
US71285805P 2005-08-31 2005-08-31
PCT/US2006/034382 WO2007028106A2 (en) 2005-08-31 2006-08-31 Host cell lines for production of antibody constant region with enhanced effector function

Publications (2)

Publication Number Publication Date
JP2009508476A JP2009508476A (ja) 2009-03-05
JP2009508476A5 true JP2009508476A5 (https=) 2009-09-24

Family

ID=37809622

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008529350A Pending JP2009508476A (ja) 2005-08-31 2006-08-31 高められたエフェクター機能をもつ抗体定常領域の製造用の宿主細胞株

Country Status (9)

Country Link
US (1) US20090214528A1 (https=)
EP (1) EP1937313A4 (https=)
JP (1) JP2009508476A (https=)
KR (1) KR20080048505A (https=)
AU (1) AU2006287224A1 (https=)
BR (1) BRPI0616600A2 (https=)
CA (1) CA2621236A1 (https=)
MX (1) MX2008003054A (https=)
WO (1) WO2007028106A2 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2704600C (en) 1999-04-09 2016-10-25 Kyowa Kirin Co., Ltd. A method for producing antibodies with increased adcc activity
FR2807767B1 (fr) * 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
US6946292B2 (en) 2000-10-06 2005-09-20 Kyowa Hakko Kogyo Co., Ltd. Cells producing antibody compositions with increased antibody dependent cytotoxic activity
SG176088A1 (en) * 2009-05-29 2011-12-29 Glaxosmithkline Llc Methods of administration of thrombopoietin agonist compounds
WO2011073235A1 (en) * 2009-12-18 2011-06-23 Csl Ltd. Method of purifying polypeptides
GB201003701D0 (en) * 2010-03-05 2010-04-21 Cilian Ag System for the expression of a protein
EP2791170A1 (en) 2011-12-16 2014-10-22 Synthon Biopharmaceuticals B.V. Compounds and methods for treating inflammatory diseases
IL292159B1 (en) 2012-12-05 2026-04-01 Alnylam Pharmaceuticals Inc PCSK9 iRNA compositions and methods of using them
US8956830B2 (en) 2013-03-14 2015-02-17 Momenta Pharmaceuticals, Inc. Methods of cell culture
US9677105B2 (en) 2013-03-14 2017-06-13 Momenta Pharmaceuticals, Inc. Methods of cell culture
US9217168B2 (en) 2013-03-14 2015-12-22 Momenta Pharmaceuticals, Inc. Methods of cell culture
JP7093612B2 (ja) * 2014-05-27 2022-06-30 アカデミア シニカ Bacteroides由来のフコシダーゼおよびそれを使用する方法
CN108348541A (zh) * 2015-08-25 2018-07-31 阿尔尼拉姆医药品有限公司 用于治疗前蛋白转化酶枯草杆菌蛋白酶kexin(pcsk9)基因相关障碍的方法和组合物
US10465003B2 (en) * 2016-02-05 2019-11-05 Janssen Biotech, Inc. Anti-TNF antibodies, compositions, methods and use for the treatment or prevention of type 1 diabetes
WO2018140121A1 (en) * 2017-01-30 2018-08-02 Janssen Biotech, Inc. Anti-tnf antibodies, compositions, and methods for the treatment of active psoriatic arthritis
MX2019009377A (es) * 2017-02-07 2019-12-11 Janssen Biotech Inc Anticuerpos anti-tnf, composiciones y metodos para el tratamiento de la espondilitis anquilosante activa.
KR102323342B1 (ko) 2019-04-26 2021-11-08 주식회사 와이바이오로직스 IL-17A 및 TNF-α에 특이적으로 결합하는 이중표적 항체
TWI875757B (zh) * 2019-05-08 2025-03-11 瑞士商諾華公司 T1dm和胰島炎治療中使用之抗cd40抗體
JP7805788B2 (ja) * 2019-05-23 2026-01-26 ヤンセン バイオテツク,インコーポレーテツド Il-23及びtnfアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
IL298389A (en) 2020-05-21 2023-01-01 Janssen Biotech Inc Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1079704A (en) 1912-06-19 1913-11-25 Dallas C Hathaway Combination tire valve-stem and pressure-gage.
EP0043718B1 (en) * 1980-07-07 1984-11-28 National Research Development Corporation Improvements in or relating to cell lines
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4816597A (en) * 1983-10-02 1989-03-28 New Jersey Institute Of Technology Dental restorative materials based upon blocked isocyanates
GB8421551D0 (en) 1984-08-24 1984-09-26 Ici Plc Water-soluble dye
PT833911E (pt) 1995-06-07 2004-09-30 Ortho Mcneil Pharm Inc Anticorpos anti-factor tecidular enxertados com cdr e metodos para a sua utilizacao
JP2001507215A (ja) * 1997-01-16 2001-06-05 サイテル コーポレイション 組換え糖タンパク質のインビトロでの実用的なシアリル化
DK1071700T3 (da) * 1998-04-20 2010-06-07 Glycart Biotechnology Ag Glykosylerings-modifikation af antistoffer til forbedring af antistofafhængig cellulær cytotoksicitet
CA2704600C (en) * 1999-04-09 2016-10-25 Kyowa Kirin Co., Ltd. A method for producing antibodies with increased adcc activity
UA81743C2 (uk) 2000-08-07 2008-02-11 Центокор, Инк. МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
US6946292B2 (en) * 2000-10-06 2005-09-20 Kyowa Hakko Kogyo Co., Ltd. Cells producing antibody compositions with increased antibody dependent cytotoxic activity
EP1360314B1 (en) 2001-02-15 2009-01-14 Centocor, Inc. Chemically defined medium for cultured mammalian cells
CA2481925A1 (en) * 2002-04-09 2003-10-16 Kyowa Hakko Kogyo Co., Ltd. Therapeutic agent for patients having human fc.gamma.riiia
BR0309145A (pt) * 2002-04-09 2005-02-01 Kyowa Hakko Kogyo Kk Células das quais o genoma é modificado
EP1498490A4 (en) * 2002-04-09 2006-11-29 Kyowa Hakko Kogyo Kk PROCESS FOR PREPARING ANTIBODY COMPOSITION
US7605235B2 (en) * 2003-05-30 2009-10-20 Centocor, Inc. Anti-tissue factor antibodies and compositions
US20050031615A1 (en) * 2003-05-30 2005-02-10 Anderson G. Mark Method of inhibiting tumor growth with anti-tissue factor antibodies

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