JP2009505980A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009505980A5 JP2009505980A5 JP2008526231A JP2008526231A JP2009505980A5 JP 2009505980 A5 JP2009505980 A5 JP 2009505980A5 JP 2008526231 A JP2008526231 A JP 2008526231A JP 2008526231 A JP2008526231 A JP 2008526231A JP 2009505980 A5 JP2009505980 A5 JP 2009505980A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- compound according
- heteroaryl
- nrr
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70742305P | 2005-08-11 | 2005-08-11 | |
| US60/707,423 | 2005-08-11 | ||
| PCT/US2006/031382 WO2007021937A2 (en) | 2005-08-11 | 2006-08-11 | Unsaturated heterocyclic derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009505980A JP2009505980A (ja) | 2009-02-12 |
| JP2009505980A5 true JP2009505980A5 (https=) | 2009-09-24 |
| JP5321061B2 JP5321061B2 (ja) | 2013-10-23 |
Family
ID=37758204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008526231A Active JP5321061B2 (ja) | 2005-08-11 | 2006-08-11 | 不飽和複素環誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8071609B2 (https=) |
| EP (1) | EP1940843A4 (https=) |
| JP (1) | JP5321061B2 (https=) |
| CA (1) | CA2618513A1 (https=) |
| WO (1) | WO2007021937A2 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20070011458A (ko) | 2004-04-08 | 2007-01-24 | 탈자진 인코포레이티드 | 키나제의 벤조트리아진 억제제 |
| PL382308A1 (pl) | 2004-08-25 | 2007-08-20 | Targegen, Inc. | Związki heterocykliczne i sposoby stosowania |
| CA2618513A1 (en) | 2005-08-11 | 2007-02-22 | Ariad Pharmaceuticals, Inc. | Unsaturated heterocyclic derivatives |
| SI2495016T1 (sl) | 2005-12-23 | 2020-04-30 | Ariad Pharmaceuticals, Inc. | Biciklične heteroarilne spojine |
| BRPI0709963A2 (pt) | 2006-04-14 | 2011-08-02 | Abbott Lab | processo para a preparação de indazolil uréias que inibem receptores de subtipo 1 de vanilóide (vr1) |
| AU2007249924B2 (en) | 2006-05-08 | 2013-07-04 | Ariad Pharmaceuticals, Inc. | Acetylenic heteroaryl compounds |
| AU2013203928B2 (en) * | 2006-05-08 | 2015-07-16 | Ariad Pharmaceuticals, Inc. | Monocyclic heteroaryl compounds |
| BRPI0710331A2 (pt) * | 2006-05-08 | 2012-03-20 | Ariad Pharmaceuticals, Inc | Compostos heteroarila monocíclicos para tratamento de câncer e composição |
| CN101490053B (zh) * | 2006-05-08 | 2013-09-11 | 阿里亚德医药股份有限公司 | 单环杂芳基化合物 |
| BRPI0817503B8 (pt) | 2007-10-05 | 2021-05-25 | Sstarbio Pte Ltd | derivados de purina substituídos por pirimidina, composição farmacêutica compreendendo ditos compostos e uso dos mesmos para a prevenção ou tratamento de uma condição proliferativa |
| PT2300013T (pt) * | 2008-05-21 | 2017-10-31 | Ariad Pharma Inc | Derivados de fósforo como inibidores de cinases |
| US9273077B2 (en) | 2008-05-21 | 2016-03-01 | Ariad Pharmaceuticals, Inc. | Phosphorus derivatives as kinase inhibitors |
| EP2365809B8 (en) | 2008-11-12 | 2018-10-10 | Ariad Pharmaceuticals, Inc. | Pyrazinopyrazines and derivatives as kinase inhibitors |
| ES2500643T3 (es) | 2009-04-03 | 2014-09-30 | Verastem, Inc. | Compuestos de purina sustituidos con pirimidina como inhibidores de las cinasas |
| TW201100441A (en) | 2009-06-01 | 2011-01-01 | Osi Pharm Inc | Amino pyrimidine anticancer compounds |
| US9133224B2 (en) | 2010-11-29 | 2015-09-15 | OSI Pharmaceuticals, LLC | Macrocyclic kinase inhibitors |
| US9834518B2 (en) | 2011-05-04 | 2017-12-05 | Ariad Pharmaceuticals, Inc. | Compounds for inhibiting cell proliferation in EGFR-driven cancers |
| AU2013250726B2 (en) * | 2012-04-20 | 2017-01-05 | Advinus Therapeutics Limited | Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof |
| US20150166591A1 (en) | 2012-05-05 | 2015-06-18 | Ariad Pharmaceuticals, Inc. | Methods and compositions for raf kinase mediated diseases |
| CA3022250A1 (en) | 2012-12-12 | 2014-06-12 | Ariad Pharmaceuticals, Inc. | Crystalline forms of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide mono hydrochloride |
| US9611283B1 (en) | 2013-04-10 | 2017-04-04 | Ariad Pharmaceuticals, Inc. | Methods for inhibiting cell proliferation in ALK-driven cancers |
| ES2896882T3 (es) | 2014-02-03 | 2022-02-28 | Quadriga Biosciences Inc | Beta-aminoácidos beta sustituidos y análogos como agentes quimioterapéuticos |
| WO2015117146A1 (en) | 2014-02-03 | 2015-08-06 | Quadriga Biosciences, Inc. | Beta-substituted gamma-amino acids and analogs as chemotherapeutic agents |
| CN108026026B (zh) | 2015-08-03 | 2021-02-09 | 夸德里加生物科学公司 | 作为化疗剂的β-取代的β-氨基酸和类似物及其应用 |
| WO2018224455A1 (en) | 2017-06-07 | 2018-12-13 | Basf Se | Substituted cyclopropyl derivatives |
| JP7598875B2 (ja) | 2019-04-12 | 2024-12-12 | リボサイエンス リミティド ライアビリティ カンパニー | エクトヌクレオチドピロホスファターゼホスホジエステラーゼ１阻害剤としての二環式ヘテロアリール誘導体 |
| CN114292269B (zh) * | 2021-12-21 | 2024-03-29 | 南昌大学 | 一种邻氨基嘌呤苯甲酰胺类衍生物及其制备方法和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5866702A (en) | 1996-08-02 | 1999-02-02 | Cv Therapeutics, Incorporation | Purine inhibitors of cyclin dependent kinase 2 |
| GB9903762D0 (en) | 1999-02-18 | 1999-04-14 | Novartis Ag | Organic compounds |
| DE60028253T2 (de) * | 1999-12-17 | 2007-03-08 | Ariad Pharmaceuticals, Inc., Cambridge | Neue purine |
| DE60209227T2 (de) | 2001-05-30 | 2006-08-17 | Novartis Ag | 2-((n-(2-amino-3-(heteroaryl- oder -aryl)propionyl)aminoacyl)amino)-alkylboronsäurederivate |
| US6770652B2 (en) * | 2001-10-18 | 2004-08-03 | Duquesne University Of The Holy Ghost | Multiple acting anti-angiogenic and cytotoxic compounds and methods for using the same |
| WO2003087087A2 (en) * | 2002-04-09 | 2003-10-23 | Astex Technology Limited | Heterocyclic compounds and their use as modulators of p38 map kinase |
| AU2003265636A1 (en) * | 2002-09-06 | 2004-03-29 | Smithkline Beecham Corporation | Pyrrolo(2, 3-d)pyrimidine-4-yl and purin-6-yl urea compounds |
| US20050054614A1 (en) | 2003-08-14 | 2005-03-10 | Diacovo Thomas G. | Methods of inhibiting leukocyte accumulation |
| CA2618513A1 (en) | 2005-08-11 | 2007-02-22 | Ariad Pharmaceuticals, Inc. | Unsaturated heterocyclic derivatives |
| SI2495016T1 (sl) | 2005-12-23 | 2020-04-30 | Ariad Pharmaceuticals, Inc. | Biciklične heteroarilne spojine |
| BRPI0710331A2 (pt) | 2006-05-08 | 2012-03-20 | Ariad Pharmaceuticals, Inc | Compostos heteroarila monocíclicos para tratamento de câncer e composição |
| EP2107054A1 (en) | 2008-04-01 | 2009-10-07 | Università Degli Studi Di Milano - Bicocca | Antiproliferative compounds and therapeutic uses thereof |
-
2006
- 2006-08-11 CA CA002618513A patent/CA2618513A1/en not_active Abandoned
- 2006-08-11 JP JP2008526231A patent/JP5321061B2/ja active Active
- 2006-08-11 US US11/990,299 patent/US8071609B2/en active Active
- 2006-08-11 EP EP20060813381 patent/EP1940843A4/en not_active Withdrawn
- 2006-08-11 WO PCT/US2006/031382 patent/WO2007021937A2/en not_active Ceased
-
2011
- 2011-12-05 US US13/311,106 patent/US8586566B2/en active Active