JP2009504748A - Ｒ（＋）プラミペキソールを用いた神経回復 - Google Patents
Ｒ（＋）プラミペキソールを用いた神経回復 Download PDFInfo
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- JP2009504748A JP2009504748A JP2008527061A JP2008527061A JP2009504748A JP 2009504748 A JP2009504748 A JP 2009504748A JP 2008527061 A JP2008527061 A JP 2008527061A JP 2008527061 A JP2008527061 A JP 2008527061A JP 2009504748 A JP2009504748 A JP 2009504748A
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- pramipexole
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- tetrahydrobenzathiazole
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
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| US70821305P | 2005-08-15 | 2005-08-15 | |
| PCT/US2006/031831 WO2007022182A1 (en) | 2005-08-15 | 2006-08-15 | Neurorestoration with r(+) pramipexole |
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| JP2012233610A Division JP2013014629A (ja) | 2005-08-15 | 2012-10-23 | Ｒ（＋）プラミペキソールを用いた神経回復 |
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| JP2009504748A true JP2009504748A (ja) | 2009-02-05 |
| JP2009504748A5 JP2009504748A5 (https=) | 2009-10-01 |
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| JP2012233610A Pending JP2013014629A (ja) | 2005-08-15 | 2012-10-23 | Ｒ（＋）プラミペキソールを用いた神経回復 |
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| JP2012233610A Pending JP2013014629A (ja) | 2005-08-15 | 2012-10-23 | Ｒ（＋）プラミペキソールを用いた神経回復 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20080234338A1 (https=) |
| EP (1) | EP1917014B1 (https=) |
| JP (2) | JP2009504748A (https=) |
| AT (1) | ATE444750T1 (https=) |
| AU (1) | AU2006279643B2 (https=) |
| CA (1) | CA2619217A1 (https=) |
| DE (1) | DE602006009670D1 (https=) |
| ES (1) | ES2334061T3 (https=) |
| IL (1) | IL189512A (https=) |
| WO (1) | WO2007022182A1 (https=) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8017598B2 (en) | 2006-05-16 | 2011-09-13 | Knopp Neurosciences, Inc. | Compositions of R(+) and S(−) pramipexole and methods of using the same |
| JP2012530723A (ja) * | 2009-06-19 | 2012-12-06 | ノップ ニューロサイエンシーズ、インク． | 筋萎縮性側索硬化症を治療するための組成物及び方法 |
| US8518926B2 (en) | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
| US8524695B2 (en) | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
| JP2016523981A (ja) * | 2013-07-12 | 2016-08-12 | ノップ バイオサイエンシーズ エルエルシー | 高好酸球値および／または高好塩基球値の治療 |
| US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
| US9642840B2 (en) | 2013-08-13 | 2017-05-09 | Knopp Biosciences, Llc | Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders |
| US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| US9763918B2 (en) | 2013-08-13 | 2017-09-19 | Knopp Biosciences Llc | Compositions and methods for treating chronic urticaria |
| US10179774B2 (en) | 2007-03-14 | 2019-01-15 | Knopp Biosciences Llc | Synthesis of chirally purified substituted benzothiazole diamines |
| US10208003B2 (en) | 2011-12-22 | 2019-02-19 | Knopp Biosciences Llc | Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
| JP2020512390A (ja) * | 2017-03-27 | 2020-04-23 | チェイス セラピューティクス コーポレイション | シヌクレイノパチーを処置するための組成物および方法 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060281797A1 (en) * | 2001-12-11 | 2006-12-14 | University Of Virginia Patent Foundation | Neurorestoration with R(+) Pramipexole |
| ES2432527T3 (es) * | 2001-12-11 | 2013-12-04 | University Of Virginia Patent Foundation | Uso de pramipexol para tratar la esclerosis lateral amiotrófica |
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| US8518926B2 (en) | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
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| US8524695B2 (en) | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
| US10179774B2 (en) | 2007-03-14 | 2019-01-15 | Knopp Biosciences Llc | Synthesis of chirally purified substituted benzothiazole diamines |
| JP2012530723A (ja) * | 2009-06-19 | 2012-12-06 | ノップ ニューロサイエンシーズ、インク． | 筋萎縮性側索硬化症を治療するための組成物及び方法 |
| US10208003B2 (en) | 2011-12-22 | 2019-02-19 | Knopp Biosciences Llc | Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2007022182A1 (en) | 2007-02-22 |
| IL189512A (en) | 2013-03-24 |
| ES2334061T3 (es) | 2010-03-04 |
| EP1917014B1 (en) | 2009-10-07 |
| AU2006279643B2 (en) | 2010-06-17 |
| AU2006279643A1 (en) | 2007-02-22 |
| IL189512A0 (en) | 2011-08-01 |
| ATE444750T1 (de) | 2009-10-15 |
| US20110218222A1 (en) | 2011-09-08 |
| EP1917014A1 (en) | 2008-05-07 |
| DE602006009670D1 (de) | 2009-11-19 |
| US20080234338A1 (en) | 2008-09-25 |
| US20130116292A1 (en) | 2013-05-09 |
| CA2619217A1 (en) | 2007-02-22 |
| JP2013014629A (ja) | 2013-01-24 |
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