JP2009504153A5 - - Google Patents
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- Publication number
- JP2009504153A5 JP2009504153A5 JP2008525967A JP2008525967A JP2009504153A5 JP 2009504153 A5 JP2009504153 A5 JP 2009504153A5 JP 2008525967 A JP2008525967 A JP 2008525967A JP 2008525967 A JP2008525967 A JP 2008525967A JP 2009504153 A5 JP2009504153 A5 JP 2009504153A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- target nucleic
- oligonucleotide
- probe
- primer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108020004707 nucleic acids Proteins 0.000 claims 71
- 150000007523 nucleic acids Chemical class 0.000 claims 71
- 102000039446 nucleic acids Human genes 0.000 claims 71
- 108091034117 Oligonucleotide Proteins 0.000 claims 45
- 239000000523 sample Substances 0.000 claims 39
- 239000013615 primer Substances 0.000 claims 30
- 238000000034 method Methods 0.000 claims 28
- 230000003321 amplification Effects 0.000 claims 16
- 238000003199 nucleic acid amplification method Methods 0.000 claims 16
- 239000012472 biological sample Substances 0.000 claims 15
- 238000001514 detection method Methods 0.000 claims 15
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims 14
- 108020005187 Oligonucleotide Probes Proteins 0.000 claims 4
- 230000001186 cumulative effect Effects 0.000 claims 4
- 238000005315 distribution function Methods 0.000 claims 4
- 239000002751 oligonucleotide probe Substances 0.000 claims 4
- 238000012360 testing method Methods 0.000 claims 4
- 238000000767 Anderson–Darling test Methods 0.000 claims 3
- 238000000692 Student's t-test Methods 0.000 claims 3
- 238000012353 t test Methods 0.000 claims 3
- 241000700605 Viruses Species 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 2
- 238000004590 computer program Methods 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000003155 DNA primer Substances 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/202,023 US20070042388A1 (en) | 2005-08-12 | 2005-08-12 | Method of probe design and/or of nucleic acids detection |
| PCT/SG2006/000224 WO2007021250A2 (en) | 2005-08-12 | 2006-08-08 | Method and/or apparatus of oligonucleotide design and/or nucleic acid detection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009504153A JP2009504153A (ja) | 2009-02-05 |
| JP2009504153A5 true JP2009504153A5 (https=) | 2009-09-24 |
Family
ID=37757981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008525967A Pending JP2009504153A (ja) | 2005-08-12 | 2006-08-08 | オリゴヌクレオチド設計および／または核酸検出の方法および／または装置 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20070042388A1 (https=) |
| EP (1) | EP1922418A4 (https=) |
| JP (1) | JP2009504153A (https=) |
| KR (1) | KR20080052585A (https=) |
| CN (1) | CN101292044B (https=) |
| AU (1) | AU2006280489B2 (https=) |
| WO (1) | WO2007021250A2 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101138864B1 (ko) * | 2005-03-08 | 2012-05-14 | 삼성전자주식회사 | 프라이머 및 프로브 세트를 설계하는 방법, 그에 의하여 설계된 프라이머 및 프로브 세트, 상기 세트를 포함하는 키트, 상기 방법을 컴퓨터가 수행할 수 있도록 하는 프로그램을기록한 컴퓨터 판독가능한 매체 및 상기 세트를 이용한 표적 서열의 동정 방법 |
| US20070042388A1 (en) * | 2005-08-12 | 2007-02-22 | Wong Christopher W | Method of probe design and/or of nucleic acids detection |
| US20100159533A1 (en) * | 2008-11-24 | 2010-06-24 | Helicos Biosciences Corporation | Simplified sample preparation for rna analysis |
| US20120264637A1 (en) * | 2009-06-26 | 2012-10-18 | The Regents Of The University Of California | Methods and systems for phylogenetic analysis |
| US20110152109A1 (en) * | 2009-12-21 | 2011-06-23 | Gardner Shea N | Biological sample target classification, detection and selection methods, and related arrays and oligonucleotide probes |
| WO2012173636A1 (en) * | 2011-06-16 | 2012-12-20 | University Of Rochester | Hiv incidence assays with high sensitivity and specificity |
| CA2872468C (en) * | 2012-05-08 | 2020-10-27 | Adaptive Biotechnologies Corporation | Compositions and methods for measuring and calibrating amplification bias in multiplexed pcr reactions |
| CN105780129B (zh) * | 2014-12-15 | 2019-06-11 | 天津华大基因科技有限公司 | 目标区域测序文库构建方法 |
| US11319602B2 (en) | 2017-02-07 | 2022-05-03 | Tcm Biotech Internationl Corp. | Probe combination for detection of cancer |
| US10787699B2 (en) * | 2017-02-08 | 2020-09-29 | Microsoft Technology Licensing, Llc | Generating pluralities of primer and payload designs for retrieval of stored nucleotides |
| JP6995604B2 (ja) * | 2017-12-15 | 2022-01-14 | 東洋鋼鈑株式会社 | 一塩基多型検出用プローブの設計方法及びプローブセット |
| CN109097450B (zh) * | 2018-08-30 | 2022-05-13 | 江苏省疾病预防控制中心 | 一种核酸序列非依赖的全rna扩增方法 |
| KR102020614B1 (ko) * | 2018-09-11 | 2019-09-11 | 한국과학기술정보연구원 | 결핵 진단용 프라이머 세트 및 이의 용도 |
| WO2020054906A1 (ko) * | 2018-09-11 | 2020-03-19 | 한국과학기술정보연구원 | 목표 유전자를 검출하기 위한 프라이머의 설계 방법 |
| CN115101128B (zh) * | 2022-06-29 | 2023-09-15 | 纳昂达(南京)生物科技有限公司 | 一种杂交捕获探针脱靶危险性评估的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000194554A (ja) * | 1998-12-25 | 2000-07-14 | Nec Corp | 演算処理装置 |
| US20030096986A1 (en) * | 2001-10-25 | 2003-05-22 | Affymetrix, Incorporated | Methods and computer software products for selecting nucleic acid probes |
| GB2377017A (en) | 2001-06-28 | 2002-12-31 | Animal Health Inst | Detection of foot and mouth disease virus |
| EP1542009B1 (en) * | 2002-08-12 | 2009-11-25 | Hitachi High-Technologies Corporation | Method of detecting nucleic acid by using dna microarrays and nucleic acid detection apparatus |
| US20040259124A1 (en) * | 2003-02-19 | 2004-12-23 | Affymetrix, Inc. | Methods for oligonucleotide probe design |
| US20070042388A1 (en) * | 2005-08-12 | 2007-02-22 | Wong Christopher W | Method of probe design and/or of nucleic acids detection |
-
2005
- 2005-08-12 US US11/202,023 patent/US20070042388A1/en not_active Abandoned
-
2006
- 2006-08-08 US US11/990,290 patent/US8234079B2/en not_active Expired - Fee Related
- 2006-08-08 CN CN2006800369768A patent/CN101292044B/zh not_active Expired - Fee Related
- 2006-08-08 EP EP06769707A patent/EP1922418A4/en not_active Withdrawn
- 2006-08-08 AU AU2006280489A patent/AU2006280489B2/en not_active Ceased
- 2006-08-08 WO PCT/SG2006/000224 patent/WO2007021250A2/en not_active Ceased
- 2006-08-08 KR KR1020087006089A patent/KR20080052585A/ko not_active Ceased
- 2006-08-08 JP JP2008525967A patent/JP2009504153A/ja active Pending
-
2012
- 2012-07-13 US US13/549,032 patent/US20120309643A1/en not_active Abandoned
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