JP2009501177A - １，４−ベンゾチアゼピン１，１−ジオキシド誘導体、その製造方法、該化合物を含有する医薬、及び脂質低下薬としてのその使用 - Google Patents

１，４−ベンゾチアゼピン１，１−ジオキシド誘導体、その製造方法、該化合物を含有する医薬、及び脂質低下薬としてのその使用 Download PDF

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Publication number
JP2009501177A
JP2009501177A JP2008520794A JP2008520794A JP2009501177A JP 2009501177 A JP2009501177 A JP 2009501177A JP 2008520794 A JP2008520794 A JP 2008520794A JP 2008520794 A JP2008520794 A JP 2008520794A JP 2009501177 A JP2009501177 A JP 2009501177A
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compound
agonist
medicament
agonists
inhibitor
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Japanese (ja)
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JP2009501177A5 (enExample
Inventor
ヴェンデリン・フリック
ハイナー・グロムビク
フーベルト・ホイアー
ハンス−ルートヴィヒ・シェーファー
シュテファン・テイス
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サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング
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Publication of JP2009501177A publication Critical patent/JP2009501177A/ja
Publication of JP2009501177A5 publication Critical patent/JP2009501177A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
JP2008520794A 2005-07-15 2006-07-13 １，４−ベンゾチアゼピン１，１−ジオキシド誘導体、その製造方法、該化合物を含有する医薬、及び脂質低下薬としてのその使用 Abandoned JP2009501177A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005033099A DE102005033099A1 (de) 2005-07-15 2005-07-15 Neues 1,4-Benzothiazepin-1,1-Dioxidderivat mit verbesserten Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindung enthaltende Arzneimittel und dessen Verwendung
PCT/EP2006/006848 WO2007009655A1 (de) 2005-07-15 2006-07-13 1,4-BENZOTHIAZEPIN-l, 1-DIOXIDDERIVAT, VERFAHREN ZU DESSEN HERSTELLUNG, DIESE VERBINDUNG ENTHALTENDE ARZNEIMITTEL UND DESSEN VERWENDUNG ALS HYPOLIPIDÄMIKUM

Publications (2)

Publication Number Publication Date
JP2009501177A true JP2009501177A (ja) 2009-01-15
JP2009501177A5 JP2009501177A5 (enExample) 2009-09-03

Family

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Family Applications (1)

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JP2008520794A Abandoned JP2009501177A (ja) 2005-07-15 2006-07-13 １，４−ベンゾチアゼピン１，１−ジオキシド誘導体、その製造方法、該化合物を含有する医薬、及び脂質低下薬としてのその使用

Country Status (18)

Country Link
US (1) US7615536B2 (enExample)
EP (1) EP1912960A1 (enExample)
JP (1) JP2009501177A (enExample)
KR (1) KR20080031738A (enExample)
CN (1) CN101223151A (enExample)
AU (1) AU2006272042A1 (enExample)
BR (1) BRPI0613462A2 (enExample)
CA (1) CA2614524A1 (enExample)
DE (1) DE102005033099A1 (enExample)
IL (1) IL188608A0 (enExample)
MA (1) MA29619B1 (enExample)
MX (1) MX2008000426A (enExample)
NO (1) NO20080789L (enExample)
NZ (1) NZ565292A (enExample)
RU (1) RU2008105756A (enExample)
TW (1) TW200745069A (enExample)
UY (1) UY29675A1 (enExample)
WO (1) WO2007009655A1 (enExample)

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EP2061767B1 (de) 2006-08-08 2014-12-17 Sanofi Arylaminoaryl-alkyl-substituierte Imidazolidin-2,4-dione, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Arzneimittel und ihre Verwendung
DE102006053635B4 (de) 2006-11-14 2011-06-30 Sanofi-Aventis Deutschland GmbH, 65929 Neue mit Benzylresten substituierte 1,4-Benzothiepin-1,1-Dioxidderivate, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
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DE102006053637B4 (de) 2006-11-14 2011-06-30 Sanofi-Aventis Deutschland GmbH, 65929 Neue mit Fluor substituierte 1,4-Benzothiepin-1,1-Dioxidderivate, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
DE102006053636B4 (de) 2006-11-14 2008-09-18 Sanofi-Aventis Deutschland Gmbh Neue mit Cyclohexylresten substituierte 1,4-Benzothiepin-1,1-Dioxidderivate und deren Verwendung
DE102007005045B4 (de) 2007-01-26 2008-12-18 Sanofi-Aventis Phenothiazin Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE102007054497B3 (de) 2007-11-13 2009-07-23 Sanofi-Aventis Deutschland Gmbh Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
US8470841B2 (en) 2008-07-09 2013-06-25 Sanofi Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
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WO2012120053A1 (de) 2011-03-08 2012-09-13 Sanofi Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
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Also Published As

Publication number Publication date
IL188608A0 (en) 2008-04-13
AU2006272042A1 (en) 2007-01-25
US7615536B2 (en) 2009-11-10
MX2008000426A (es) 2008-03-10
DE102005033099A1 (de) 2007-01-18
NZ565292A (en) 2010-01-29
KR20080031738A (ko) 2008-04-10
TW200745069A (en) 2007-12-16
WO2007009655A1 (de) 2007-01-25
NO20080789L (no) 2008-02-13
CA2614524A1 (en) 2007-01-25
CN101223151A (zh) 2008-07-16
UY29675A1 (es) 2007-02-28
MA29619B1 (fr) 2008-07-01
US20080207534A1 (en) 2008-08-28
RU2008105756A (ru) 2009-08-20
EP1912960A1 (de) 2008-04-23
BRPI0613462A2 (pt) 2011-01-11

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