JP2009500620A5 - - Google Patents
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- Publication number
- JP2009500620A5 JP2009500620A5 JP2008520024A JP2008520024A JP2009500620A5 JP 2009500620 A5 JP2009500620 A5 JP 2009500620A5 JP 2008520024 A JP2008520024 A JP 2008520024A JP 2008520024 A JP2008520024 A JP 2008520024A JP 2009500620 A5 JP2009500620 A5 JP 2009500620A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- aspergillus
- dppv
- rnu
- serum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 claims 43
- 102000036639 antigens Human genes 0.000 claims 43
- 108091007433 antigens Proteins 0.000 claims 43
- 238000000034 method Methods 0.000 claims 25
- 241000228212 Aspergillus Species 0.000 claims 23
- 102000016938 Catalase Human genes 0.000 claims 9
- 108010053835 Catalase Proteins 0.000 claims 9
- 101710087092 Dipeptidyl-peptidase 5 Proteins 0.000 claims 9
- 101710168595 Probable dipeptidyl-peptidase 5 Proteins 0.000 claims 9
- 102000006382 Ribonucleases Human genes 0.000 claims 9
- 108010083644 Ribonucleases Proteins 0.000 claims 9
- 238000009007 Diagnostic Kit Methods 0.000 claims 8
- 238000002965 ELISA Methods 0.000 claims 8
- 210000002966 serum Anatomy 0.000 claims 8
- 201000002909 Aspergillosis Diseases 0.000 claims 6
- 208000036641 Aspergillus infections Diseases 0.000 claims 6
- 239000007787 solid Substances 0.000 claims 5
- OMDQUFIYNPYJFM-XKDAHURESA-N (2r,3r,4s,5r,6s)-2-(hydroxymethyl)-6-[[(2r,3s,4r,5s,6r)-4,5,6-trihydroxy-3-[(2s,3s,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)O)[C@H](O)[C@H](O)[C@H](O)O1 OMDQUFIYNPYJFM-XKDAHURESA-N 0.000 claims 4
- 102000004190 Enzymes Human genes 0.000 claims 4
- 108090000790 Enzymes Proteins 0.000 claims 4
- 229920000926 Galactomannan Polymers 0.000 claims 4
- 206010006474 Bronchopulmonary aspergillosis allergic Diseases 0.000 claims 3
- 208000006778 allergic bronchopulmonary aspergillosis Diseases 0.000 claims 3
- 239000002299 complementary DNA Substances 0.000 claims 3
- 201000003883 Cystic fibrosis Diseases 0.000 claims 2
- 238000002835 absorbance Methods 0.000 claims 2
- 230000003321 amplification Effects 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 2
- 239000003550 marker Substances 0.000 claims 2
- 238000003199 nucleic acid amplification method Methods 0.000 claims 2
- 239000000243 solution Substances 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 206010003487 Aspergilloma Diseases 0.000 claims 1
- 241001225321 Aspergillus fumigatus Species 0.000 claims 1
- 206010062016 Immunosuppression Diseases 0.000 claims 1
- 229940091771 aspergillus fumigatus Drugs 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000010367 cloning Methods 0.000 claims 1
- 230000007812 deficiency Effects 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 230000001506 immunosuppresive effect Effects 0.000 claims 1
- 201000009085 invasive aspergillosis Diseases 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
- 239000011534 wash buffer Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05291428.0 | 2005-07-01 | ||
| EP05291428A EP1739428A1 (en) | 2005-07-01 | 2005-07-01 | In vitro diagnostic method and kit for an aspergillus infection |
| PCT/IB2006/003039 WO2007015177A2 (en) | 2005-07-01 | 2006-06-30 | In vitro diagnostic method and kit for an aspergillus infection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009500620A JP2009500620A (ja) | 2009-01-08 |
| JP2009500620A5 true JP2009500620A5 (enExample) | 2009-07-30 |
| JP4959697B2 JP4959697B2 (ja) | 2012-06-27 |
Family
ID=35385774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008520024A Active JP4959697B2 (ja) | 2005-07-01 | 2006-06-30 | アスペルギルス感染のためのin vitro診断法およびキット |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7888041B2 (enExample) |
| EP (2) | EP1739428A1 (enExample) |
| JP (1) | JP4959697B2 (enExample) |
| AT (1) | ATE415629T1 (enExample) |
| CA (1) | CA2613727C (enExample) |
| DE (1) | DE602006003903D1 (enExample) |
| ES (1) | ES2318799T3 (enExample) |
| WO (1) | WO2007015177A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10288611B2 (en) | 2009-11-23 | 2019-05-14 | The Johns Hopkins University | Lateral flow device for diagnosing microbial infections |
| US10585098B2 (en) | 2009-11-23 | 2020-03-10 | The Johns Hopkins University | Optimizing diagnostics for galactofuranose containing antigens |
| CN102174485B (zh) * | 2011-02-18 | 2013-07-17 | 中国人民解放军南京军区南京总医院 | 一种曲霉免疫优势抗原及用途 |
| US20140178884A1 (en) * | 2011-05-23 | 2014-06-26 | Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The Univ. Of Nevada, Reno | Method of diagnosing and treating an aspergillus species-associated condition |
| WO2015095195A1 (en) | 2013-12-16 | 2015-06-25 | The Johns Hopkins University | Interferon-gamma release assays for diagnosis of invasive fungal infections |
| CN110954696A (zh) * | 2019-11-27 | 2020-04-03 | 深圳华瑞达生物科技有限公司 | 一种曲霉半乳甘露聚糖聚糖检测试剂盒及其应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8919671D0 (en) * | 1989-08-31 | 1989-10-11 | Bush Boake Allen Ltd | Biotransformation of fatty substrates |
| SE9604815D0 (sv) * | 1996-12-20 | 1996-12-20 | Pharmacia & Upjohn Ab | A metod of diagnosis |
| DK1141371T3 (da) * | 1998-12-23 | 2009-02-02 | Novozymes As | Fremgangsmåder til fremstilling af polypeptider i Aspergillus-mutantceller |
| EP1104768B1 (en) * | 1999-12-02 | 2006-11-29 | Council of Scientific and Industrial Research | Peptide sequences from aspergillus fumigatus for the diagnosis of aspergillosis |
| JP2002223772A (ja) * | 2001-02-01 | 2002-08-13 | Gekkeikan Sake Co Ltd | カタラーゼa遺伝子 |
-
2005
- 2005-07-01 EP EP05291428A patent/EP1739428A1/en not_active Withdrawn
-
2006
- 2006-06-30 US US11/988,038 patent/US7888041B2/en active Active
- 2006-06-30 WO PCT/IB2006/003039 patent/WO2007015177A2/en not_active Ceased
- 2006-06-30 ES ES06809138T patent/ES2318799T3/es active Active
- 2006-06-30 DE DE602006003903T patent/DE602006003903D1/de active Active
- 2006-06-30 CA CA2613727A patent/CA2613727C/en active Active
- 2006-06-30 JP JP2008520024A patent/JP4959697B2/ja active Active
- 2006-06-30 EP EP06809138A patent/EP1907853B1/en active Active
- 2006-06-30 AT AT06809138T patent/ATE415629T1/de active
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