JP2008546672A5 - - Google Patents
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- Publication number
- JP2008546672A5 JP2008546672A5 JP2008516350A JP2008516350A JP2008546672A5 JP 2008546672 A5 JP2008546672 A5 JP 2008546672A5 JP 2008516350 A JP2008516350 A JP 2008516350A JP 2008516350 A JP2008516350 A JP 2008516350A JP 2008546672 A5 JP2008546672 A5 JP 2008546672A5
- Authority
- JP
- Japan
- Prior art keywords
- ifn
- pharmaceutical composition
- sequence encoding
- family cytokine
- pegylated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000006992 Interferon-alpha Human genes 0.000 claims description 25
- 108010047761 Interferon-alpha Proteins 0.000 claims description 25
- OHDXDNUPVVYWOV-UHFFFAOYSA-N n-methyl-1-(2-naphthalen-1-ylsulfanylphenyl)methanamine Chemical compound CNCC1=CC=CC=C1SC1=CC=CC2=CC=CC=C12 OHDXDNUPVVYWOV-UHFFFAOYSA-N 0.000 claims description 25
- 102000004127 Cytokines Human genes 0.000 claims description 17
- 108090000695 Cytokines Proteins 0.000 claims description 17
- 108090001005 Interleukin-6 Proteins 0.000 claims description 16
- 239000008194 pharmaceutical composition Substances 0.000 claims description 13
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 11
- 102100039948 Interferon alpha-5 Human genes 0.000 claims 6
- 101710127457 Interferon alpha-5 Proteins 0.000 claims 6
- 239000000546 pharmaceutical excipient Substances 0.000 claims 4
- 102100028892 Cardiotrophin-1 Human genes 0.000 claims 3
- 208000005176 Hepatitis C Diseases 0.000 claims 3
- 102000014150 Interferons Human genes 0.000 claims 3
- 108010050904 Interferons Proteins 0.000 claims 3
- 108090000630 Oncostatin M Proteins 0.000 claims 3
- 102000004140 Oncostatin M Human genes 0.000 claims 3
- 108010041776 cardiotrophin 1 Proteins 0.000 claims 3
- 229940079322 interferon Drugs 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 239000012876 carrier material Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000000969 carrier Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200501468A ES2302402B1 (es) | 2005-06-16 | 2005-06-16 | Uso de una citoquina de la familia de interleuquina-6 en la preparacion de una composicion para administracion combinada con interferon-alfa. |
| ESP200501468 | 2005-06-16 | ||
| PCT/ES2006/000353 WO2006134195A2 (es) | 2005-06-16 | 2006-06-16 | Uso de una citoquina de la familia de interleuquina-6 en la preparación de una composición para administración combinada con interperón-alfa |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008546672A JP2008546672A (ja) | 2008-12-25 |
| JP2008546672A5 true JP2008546672A5 (enExample) | 2012-11-29 |
| JP5154412B2 JP5154412B2 (ja) | 2013-02-27 |
Family
ID=37532659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008516350A Expired - Fee Related JP5154412B2 (ja) | 2005-06-16 | 2006-06-16 | インターフェロンアルファとの組み合わせ投与のための組成物の調製における、インターロイキン6ファミリーサイトカインの使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7829077B2 (enExample) |
| EP (1) | EP1905447A4 (enExample) |
| JP (1) | JP5154412B2 (enExample) |
| CN (1) | CN101257918B (enExample) |
| AU (1) | AU2006258966B8 (enExample) |
| BR (1) | BRPI0611988A2 (enExample) |
| CA (1) | CA2612282C (enExample) |
| ES (1) | ES2302402B1 (enExample) |
| MX (1) | MX2007016060A (enExample) |
| RU (1) | RU2413529C2 (enExample) |
| WO (1) | WO2006134195A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA106591C2 (uk) * | 2008-07-23 | 2014-09-25 | Тамара Алєксандровна Віткалова | Спосіб лікування гепатиту с з використанням інтерферону та інтерлейкіну-1 |
| JP2010059081A (ja) * | 2008-09-02 | 2010-03-18 | Okayama Univ | オンコスタチンmを含有する抗hcv剤およびその利用 |
| ES2342529B1 (es) * | 2008-10-07 | 2011-05-11 | Proyecto De Biomedicina Cima, S.L. | Oncostatina m como potenciador de la actividad inmunoestimuladora de celulas epiteliales humanas. |
| US20120308517A1 (en) * | 2010-02-09 | 2012-12-06 | Digna Biotech, S.L. | Compositions for the treatment of infectious and tumoural diseases |
| WO2017197036A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Spirocyclic degronimers for target protein degradation |
| WO2017197051A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Amine-linked c3-glutarimide degronimers for target protein degradation |
| EP3454856B1 (en) | 2016-05-10 | 2024-09-11 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
| EP3455218A4 (en) | 2016-05-10 | 2019-12-18 | C4 Therapeutics, Inc. | C3 CARBON-BASED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION |
| JP7264867B2 (ja) | 2017-03-31 | 2023-04-25 | アッカニス・バイオテック・エフ・アンド・イー・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング・ウント・コムパニー・コマンディットゲゼルシャフト | 非メラノーマ皮膚癌(nmsc)の予防および治療 |
| CN110769822A (zh) | 2017-06-20 | 2020-02-07 | C4医药公司 | 用于蛋白降解的n/o-连接的降解决定子和降解决定子体 |
| CN113197910B (zh) * | 2021-05-14 | 2022-09-23 | 苏州大学 | 一种基于阿司匹林及其代谢产物提高干扰素抗病毒活性的抗病毒药盒 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE67035B1 (en) * | 1986-07-08 | 1996-02-21 | Genetics Inst | Production and use of non-glycosylated IL-6 |
| US6284237B1 (en) | 1986-07-08 | 2001-09-04 | Steven C. Clark | Methods of treatment using IL-6 |
| US6348191B1 (en) | 1986-07-08 | 2002-02-19 | Genetics Institute, Inc. | Production and use of IL-6 |
| US5372808A (en) * | 1990-10-17 | 1994-12-13 | Amgen Inc. | Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect |
| US5766582A (en) | 1994-10-11 | 1998-06-16 | Schering Corporation | Stable, aqueous alfa interferon solution formulations |
| JP2758154B2 (ja) | 1995-04-06 | 1998-05-28 | エフ・ホフマン−ラ ロシユ アーゲー | インターフェロンを含む液体製剤 |
| US5908621A (en) | 1995-11-02 | 1999-06-01 | Schering Corporation | Polyethylene glycol modified interferon therapy |
| CA2329474C (en) * | 1995-11-02 | 2002-02-26 | Schering Corporation | Continuous low-dose cytokine infusion therapy |
| GB9609932D0 (en) * | 1996-05-13 | 1996-07-17 | Hoffmann La Roche | Use of IL-12 and IFN alpha for the treatment of infectious diseases |
| EP1860192A1 (en) * | 1996-09-17 | 2007-11-28 | Novartis Vaccines and Diagnostics, Inc. | Compositions and methods for treating intracellular diseases |
| AR013269A1 (es) * | 1997-08-04 | 2000-12-13 | Scras | Producto que contiene por lo menos un rna de doble filamento combinado con por lo menos un agente anti-viral, para la utilizacion terapeutica en eltratamiento de una enfermedad viral, en especial de la hepatitis viral |
| AU2158000A (en) | 1998-12-22 | 2000-07-12 | Schering Corporation | Treatment of hepatitis c virus infections with interleukin-10 |
| ES2200646B1 (es) * | 2001-09-21 | 2005-05-01 | Fundacion Para La Investigacion Medica Aplicada | Uso de la cardiotrofina en enfermedades hepaticas. |
| TW200408407A (en) * | 2001-11-30 | 2004-06-01 | Dana Farber Cancer Inst Inc | Methods and compositions for modulating the immune system and uses thereof |
| RU2222345C2 (ru) * | 2002-01-21 | 2004-01-27 | Волчек Игорь Анатольевич | Фармацевтическая композиция цитокинового и иммуномодулирующего действия |
| US20050027110A1 (en) * | 2003-07-24 | 2005-02-03 | Michael Russell | Drug delivery in the nervous system |
-
2005
- 2005-06-16 ES ES200501468A patent/ES2302402B1/es not_active Expired - Fee Related
-
2006
- 2006-06-16 US US11/922,221 patent/US7829077B2/en not_active Expired - Fee Related
- 2006-06-16 CN CN2006800299002A patent/CN101257918B/zh not_active Expired - Fee Related
- 2006-06-16 WO PCT/ES2006/000353 patent/WO2006134195A2/es not_active Ceased
- 2006-06-16 JP JP2008516350A patent/JP5154412B2/ja not_active Expired - Fee Related
- 2006-06-16 BR BRPI0611988-3A patent/BRPI0611988A2/pt not_active IP Right Cessation
- 2006-06-16 MX MX2007016060A patent/MX2007016060A/es active IP Right Grant
- 2006-06-16 AU AU2006258966A patent/AU2006258966B8/en not_active Ceased
- 2006-06-16 RU RU2008100307/15A patent/RU2413529C2/ru not_active IP Right Cessation
- 2006-06-16 EP EP06794028A patent/EP1905447A4/en not_active Withdrawn
- 2006-06-16 CA CA2612282A patent/CA2612282C/en not_active Expired - Fee Related
-
2010
- 2010-09-22 US US12/887,843 patent/US20110027224A1/en not_active Abandoned
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