RU2413529C2 - Применение цитокина из семейства интерлейкина-6 для получения композиции для комбинированного введения с интерфероном-альфа - Google Patents
Применение цитокина из семейства интерлейкина-6 для получения композиции для комбинированного введения с интерфероном-альфа Download PDFInfo
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61P31/20—Antivirals for DNA viruses
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5415—Leukaemia inhibitory factor [LIF]
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5431—IL-11
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- C07—ORGANIC CHEMISTRY
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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| ES200501468A ES2302402B1 (es) | 2005-06-16 | 2005-06-16 | Uso de una citoquina de la familia de interleuquina-6 en la preparacion de una composicion para administracion combinada con interferon-alfa. |
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| UA106591C2 (uk) * | 2008-07-23 | 2014-09-25 | Тамара Алєксандровна Віткалова | Спосіб лікування гепатиту с з використанням інтерферону та інтерлейкіну-1 |
| JP2010059081A (ja) * | 2008-09-02 | 2010-03-18 | Okayama Univ | オンコスタチンmを含有する抗hcv剤およびその利用 |
| ES2342529B1 (es) | 2008-10-07 | 2011-05-11 | Proyecto De Biomedicina Cima, S.L. | Oncostatina m como potenciador de la actividad inmunoestimuladora de celulas epiteliales humanas. |
| WO2011098644A2 (es) | 2010-02-09 | 2011-08-18 | Proyecto De Biomedicina Cima, S.L. | Composiciones para el tratamiento de enfermedades infecciosas y tumorales |
| WO2017197046A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | C3-carbon linked glutarimide degronimers for target protein degradation |
| WO2017197055A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
| EP3454862B1 (en) | 2016-05-10 | 2024-09-11 | C4 Therapeutics, Inc. | Spirocyclic degronimers for target protein degradation |
| EP3455219A4 (en) | 2016-05-10 | 2019-12-18 | C4 Therapeutics, Inc. | AMINE-RELATED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION |
| CN110636854A (zh) | 2017-03-31 | 2019-12-31 | 阿卡尼斯生物技术F&E有限责任两合公司 | 非黑素瘤皮肤癌(nmsc)的预防和治疗 |
| CN110769822A (zh) | 2017-06-20 | 2020-02-07 | C4医药公司 | 用于蛋白降解的n/o-连接的降解决定子和降解决定子体 |
| CN113197910B (zh) * | 2021-05-14 | 2022-09-23 | 苏州大学 | 一种基于阿司匹林及其代谢产物提高干扰素抗病毒活性的抗病毒药盒 |
Citations (3)
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| EP0858343A1 (en) * | 1995-11-02 | 1998-08-19 | Schering Corporation | Continuous low-dose cytokine infusion therapy |
| RU2128056C1 (ru) * | 1992-04-15 | 1999-03-27 | Амген Инк. | Способы и препараты для лечения заболеваний интерфероном, характеризующиеся сниженными побочными эффектами |
| RU2222345C2 (ru) * | 2002-01-21 | 2004-01-27 | Волчек Игорь Анатольевич | Фармацевтическая композиция цитокинового и иммуномодулирующего действия |
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| US6284237B1 (en) | 1986-07-08 | 2001-09-04 | Steven C. Clark | Methods of treatment using IL-6 |
| US6348191B1 (en) | 1986-07-08 | 2002-02-19 | Genetics Institute, Inc. | Production and use of IL-6 |
| IE67035B1 (en) * | 1986-07-08 | 1996-02-21 | Genetics Inst | Production and use of non-glycosylated IL-6 |
| US5766582A (en) | 1994-10-11 | 1998-06-16 | Schering Corporation | Stable, aqueous alfa interferon solution formulations |
| JP2758154B2 (ja) | 1995-04-06 | 1998-05-28 | エフ・ホフマン−ラ ロシユ アーゲー | インターフェロンを含む液体製剤 |
| US5908621A (en) | 1995-11-02 | 1999-06-01 | Schering Corporation | Polyethylene glycol modified interferon therapy |
| GB9609932D0 (en) * | 1996-05-13 | 1996-07-17 | Hoffmann La Roche | Use of IL-12 and IFN alpha for the treatment of infectious diseases |
| WO1998012332A1 (en) * | 1996-09-17 | 1998-03-26 | Chiron Corporation | Compositions and methods for treating intracellular diseases |
| AR013269A1 (es) * | 1997-08-04 | 2000-12-13 | Scras | Producto que contiene por lo menos un rna de doble filamento combinado con por lo menos un agente anti-viral, para la utilizacion terapeutica en eltratamiento de una enfermedad viral, en especial de la hepatitis viral |
| US6685931B1 (en) | 1998-12-22 | 2004-02-03 | Schering Corporation | Treatment of hepatitis C virus infections with interleukin-10 |
| ES2200646B1 (es) * | 2001-09-21 | 2005-05-01 | Fundacion Para La Investigacion Medica Aplicada | Uso de la cardiotrofina en enfermedades hepaticas. |
| TW200408407A (en) * | 2001-11-30 | 2004-06-01 | Dana Farber Cancer Inst Inc | Methods and compositions for modulating the immune system and uses thereof |
| US20050027110A1 (en) * | 2003-07-24 | 2005-02-03 | Michael Russell | Drug delivery in the nervous system |
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2005
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| RU2128056C1 (ru) * | 1992-04-15 | 1999-03-27 | Амген Инк. | Способы и препараты для лечения заболеваний интерфероном, характеризующиеся сниженными побочными эффектами |
| EP0858343A1 (en) * | 1995-11-02 | 1998-08-19 | Schering Corporation | Continuous low-dose cytokine infusion therapy |
| RU2222345C2 (ru) * | 2002-01-21 | 2004-01-27 | Волчек Игорь Анатольевич | Фармацевтическая композиция цитокинового и иммуномодулирующего действия |
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| Patterson ВК, Tjernlund A, Andersson J. «Endogenous inhibitors of HIV: potent anti-HIV activity of leukemia inhibitory factor.», Curr Mol Med. 2002 Dec; 2(8):713-22. * |
| Цитокины и воспаление, том 1, №1, 2002, А.С.Симбирцев, стр.10, 16. * |
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| WO2006134195A8 (es) | 2008-01-31 |
| AU2006258966B8 (en) | 2011-12-08 |
| JP5154412B2 (ja) | 2013-02-27 |
| ES2302402B1 (es) | 2009-05-08 |
| US7829077B2 (en) | 2010-11-09 |
| WO2006134195A2 (es) | 2006-12-21 |
| EP1905447A2 (en) | 2008-04-02 |
| ES2302402A1 (es) | 2008-07-01 |
| CA2612282A1 (en) | 2006-12-21 |
| US20110027224A1 (en) | 2011-02-03 |
| CN101257918A (zh) | 2008-09-03 |
| AU2006258966B2 (en) | 2011-11-17 |
| CA2612282C (en) | 2014-03-25 |
| EP1905447A4 (en) | 2012-04-25 |
| CN101257918B (zh) | 2011-09-21 |
| BRPI0611988A2 (pt) | 2010-10-13 |
| WO2006134195A3 (es) | 2007-04-19 |
| RU2008100307A (ru) | 2009-07-27 |
| US20090130055A1 (en) | 2009-05-21 |
| AU2006258966A1 (en) | 2006-12-21 |
| MX2007016060A (es) | 2008-03-10 |
| JP2008546672A (ja) | 2008-12-25 |
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