JP2008546406A5 - - Google Patents
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- JP2008546406A5 JP2008546406A5 JP2008518189A JP2008518189A JP2008546406A5 JP 2008546406 A5 JP2008546406 A5 JP 2008546406A5 JP 2008518189 A JP2008518189 A JP 2008518189A JP 2008518189 A JP2008518189 A JP 2008518189A JP 2008546406 A5 JP2008546406 A5 JP 2008546406A5
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- Prior art keywords
- implantable material
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- cells
- cell population
- Prior art date
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- 239000000463 material Substances 0.000 claims 71
- 210000004027 cell Anatomy 0.000 claims 57
- 239000000203 mixture Substances 0.000 claims 51
- 238000000034 method Methods 0.000 claims 20
- 239000006163 transport media Substances 0.000 claims 20
- 239000011159 matrix material Substances 0.000 claims 14
- 239000000090 biomarker Substances 0.000 claims 10
- 210000002889 endothelial cell Anatomy 0.000 claims 8
- 229920002971 Heparan sulfate Polymers 0.000 claims 7
- 238000004113 cell culture Methods 0.000 claims 7
- 230000003833 cell viability Effects 0.000 claims 7
- 230000002401 inhibitory effect Effects 0.000 claims 7
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 6
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 6
- 102000004887 Transforming Growth Factor beta Human genes 0.000 claims 5
- 108090001012 Transforming Growth Factor beta Proteins 0.000 claims 5
- 239000000758 substrate Substances 0.000 claims 5
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 claims 5
- 239000012595 freezing medium Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 238000005138 cryopreservation Methods 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 239000002245 particle Substances 0.000 claims 3
- 108091003079 Bovine Serum Albumin Proteins 0.000 claims 2
- 229920002307 Dextran Polymers 0.000 claims 2
- 108010010803 Gelatin Proteins 0.000 claims 2
- 230000003698 anagen phase Effects 0.000 claims 2
- 230000008619 cell matrix interaction Effects 0.000 claims 2
- 239000012091 fetal bovine serum Substances 0.000 claims 2
- 230000009969 flowable effect Effects 0.000 claims 2
- 239000008273 gelatin Substances 0.000 claims 2
- 229920000159 gelatin Polymers 0.000 claims 2
- 235000019322 gelatine Nutrition 0.000 claims 2
- 235000011852 gelatine desserts Nutrition 0.000 claims 2
- 150000004676 glycans Chemical class 0.000 claims 2
- 230000007774 longterm Effects 0.000 claims 2
- 210000004962 mammalian cell Anatomy 0.000 claims 2
- 239000013028 medium composition Substances 0.000 claims 2
- 229920001282 polysaccharide Polymers 0.000 claims 2
- 239000005017 polysaccharide Substances 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 210000000130 stem cell Anatomy 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 1
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- 102000009123 Fibrin Human genes 0.000 claims 1
- 108010073385 Fibrin Proteins 0.000 claims 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 1
- 102000003974 Fibroblast growth factor 2 Human genes 0.000 claims 1
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 claims 1
- 229920000954 Polyglycolide Polymers 0.000 claims 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 1
- 102000046299 Transforming Growth Factor beta1 Human genes 0.000 claims 1
- 101800002279 Transforming growth factor beta-1 Proteins 0.000 claims 1
- 229940072056 alginate Drugs 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 229960002086 dextran Drugs 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 239000006260 foam Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 210000005260 human cell Anatomy 0.000 claims 1
- 239000003094 microcapsule Substances 0.000 claims 1
- -1 microcarrier Substances 0.000 claims 1
- 229920000747 poly(lactic acid) Polymers 0.000 claims 1
- 229920001467 poly(styrenesulfonates) Polymers 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 229940006186 sodium polystyrene sulfonate Drugs 0.000 claims 1
- 229940099456 transforming growth factor beta 1 Drugs 0.000 claims 1
- 230000023750 transforming growth factor beta production Effects 0.000 claims 1
- 230000007704 transition Effects 0.000 claims 1
- 210000003556 vascular endothelial cell Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69270805P | 2005-06-21 | 2005-06-21 | |
| US60/692,708 | 2005-06-21 | ||
| USPCT/US2005/043967 | 2005-12-06 | ||
| PCT/US2005/043967 WO2006062909A2 (en) | 2004-12-08 | 2005-12-06 | Methods and compositions for enhancing vascular access |
| PCT/US2006/021755 WO2007001744A2 (en) | 2005-06-21 | 2006-06-05 | Methods and compositions for enhancing vascular access |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012133043A Division JP2012166084A (ja) | 2005-06-21 | 2012-06-12 | 脈管アクセスを改善するための方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008546406A JP2008546406A (ja) | 2008-12-25 |
| JP2008546406A5 true JP2008546406A5 (https=) | 2009-07-16 |
| JP5632580B2 JP5632580B2 (ja) | 2014-11-26 |
Family
ID=39892157
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008518189A Expired - Fee Related JP5632580B2 (ja) | 2005-06-21 | 2006-06-05 | 脈管アクセスを改善するための方法および組成物 |
| JP2012133043A Withdrawn JP2012166084A (ja) | 2005-06-21 | 2012-06-12 | 脈管アクセスを改善するための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012133043A Withdrawn JP2012166084A (ja) | 2005-06-21 | 2012-06-12 | 脈管アクセスを改善するための方法および組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20090035346A1 (https=) |
| EP (2) | EP1901680B1 (https=) |
| JP (2) | JP5632580B2 (https=) |
| CN (3) | CN102743792B (https=) |
| AU (1) | AU2006262682B2 (https=) |
| CA (2) | CA2818182C (https=) |
| ES (1) | ES2541684T3 (https=) |
| IL (2) | IL188263A (https=) |
| SG (2) | SG161258A1 (https=) |
| WO (1) | WO2007001744A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2926510B2 (ja) | 1990-08-09 | 1999-07-28 | 京都電子工業株式会社 | アンモニア濃度測定装置 |
| DE602006014814D1 (de) | 2005-04-21 | 2010-07-22 | Massachusetts Inst Technology | Materialien und verfahren zur änderung einer immunreaktion auf exogene und endogene immunogene, einschliesslich genidentischer und nicht-genidentischer zellen, gewebe oder organe |
| EP1901680B1 (en) | 2005-06-21 | 2015-04-15 | Shire Regenerative Medicine, Inc. | Crypreservation of biocompatible material |
| WO2008057580A2 (en) * | 2006-11-07 | 2008-05-15 | Pervasis Therapeutics, Inc. | Materials and methods for treating and managing angiogenesis-mediated diseases |
| WO2008057590A2 (en) * | 2006-11-07 | 2008-05-15 | Pervasis Therapeutics, Inc. | Methods and compositions for modulating tissue modeling |
| EP2240116B1 (en) | 2008-01-28 | 2015-07-01 | Biomet 3I, LLC | Implant surface with increased hydrophilicity |
| JP6038123B2 (ja) | 2011-04-28 | 2016-12-07 | アブラクシス バイオサイエンス， エルエルシー | ナノ粒子組成物の脈管内送達およびそれらの使用 |
| CN102763642B (zh) * | 2012-08-14 | 2014-04-02 | 郑州赛英科干细胞技术有限公司 | 一种冷冻保护液以及冷冻保存人胎盘羊膜和绒毛膜的方法 |
| WO2015181245A1 (en) * | 2014-05-27 | 2015-12-03 | Novahep Ab | Bioengineered allogeneic valve |
| EP3267951A4 (en) * | 2015-03-10 | 2018-12-19 | Stent Tek Limited | Surgical system, device and methods of use thereof for the percutaneous creation of an arteriovenous fistula (avf) |
| US11389622B1 (en) * | 2017-11-13 | 2022-07-19 | Simon B. Rayhanabad | Patch for providing dialysis |
| US12017032B1 (en) | 2017-11-13 | 2024-06-25 | Sbr Innovations, Llc | Arteriovenous graft and method of using thereof |
| WO2019152799A1 (en) | 2018-02-02 | 2019-08-08 | University Of Louisville Research Foundation, Inc. | Sutureless graft anastomotic quick connect system |
| EP3843798A1 (en) * | 2018-08-31 | 2021-07-07 | Wisconsin Alumni Research Foundation | Generating arterial endothelial cell-seeded vascular grafts |
| US12310836B2 (en) | 2020-03-03 | 2025-05-27 | Akeo Hagiwara | Vein cover |
| CN115376392B (zh) * | 2022-08-18 | 2024-04-26 | 昆明理工大学 | 主动脉老化对血管生物力学影响的模拟装置及方法 |
| EP4439070B1 (de) * | 2023-03-27 | 2025-12-03 | Siemens Healthcare Diagnostics Products GmbH | Automatisches analysesystem |
| CN120227529B (zh) * | 2025-05-29 | 2025-08-12 | 鼎科医疗技术（苏州）有限公司 | 一种血管外支架 |
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| GB0509845D0 (en) | 2005-05-13 | 2005-06-22 | Btg Int Ltd | Preparation of therapeutic foam |
| EP1901680B1 (en) | 2005-06-21 | 2015-04-15 | Shire Regenerative Medicine, Inc. | Crypreservation of biocompatible material |
| WO2007047425A1 (en) | 2005-10-12 | 2007-04-26 | Cellular Bioengineering, Inc. | Resorbable cornea button |
| US7882863B2 (en) * | 2005-10-19 | 2011-02-08 | Cd Solutions, Llc | Apparatus and method for mixing and transferring medications |
| EP1951344B1 (en) * | 2005-11-07 | 2014-05-28 | Industrie Borla SpA | Vented safe handling vial adapter |
-
2006
- 2006-06-05 EP EP20060772165 patent/EP1901680B1/en not_active Not-in-force
- 2006-06-05 SG SG201002482-6A patent/SG161258A1/en unknown
- 2006-06-05 WO PCT/US2006/021755 patent/WO2007001744A2/en not_active Ceased
- 2006-06-05 AU AU2006262682A patent/AU2006262682B2/en not_active Ceased
- 2006-06-05 US US11/922,729 patent/US20090035346A1/en not_active Abandoned
- 2006-06-05 CA CA 2818182 patent/CA2818182C/en not_active Expired - Fee Related
- 2006-06-05 EP EP20110001333 patent/EP2361591A3/en not_active Withdrawn
- 2006-06-05 CN CN201210246619.1A patent/CN102743792B/zh not_active Expired - Fee Related
- 2006-06-05 CN CN2006800279776A patent/CN101257861B/zh not_active Expired - Fee Related
- 2006-06-05 CN CN2010102362140A patent/CN101878757A/zh active Pending
- 2006-06-05 SG SG2013075387A patent/SG195537A1/en unknown
- 2006-06-05 JP JP2008518189A patent/JP5632580B2/ja not_active Expired - Fee Related
- 2006-06-05 ES ES06772165.4T patent/ES2541684T3/es active Active
- 2006-06-05 CA CA 2612751 patent/CA2612751A1/en not_active Abandoned
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2007
- 2007-12-19 IL IL188263A patent/IL188263A/en not_active IP Right Cessation
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2012
- 2012-06-12 JP JP2012133043A patent/JP2012166084A/ja not_active Withdrawn
- 2012-07-05 IL IL220806A patent/IL220806A/en not_active IP Right Cessation
- 2012-11-02 US US13/667,227 patent/US9023377B2/en not_active Expired - Fee Related
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