JP2008546390A5 - - Google Patents
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- JP2008546390A5 JP2008546390A5 JP2008517126A JP2008517126A JP2008546390A5 JP 2008546390 A5 JP2008546390 A5 JP 2008546390A5 JP 2008517126 A JP2008517126 A JP 2008517126A JP 2008517126 A JP2008517126 A JP 2008517126A JP 2008546390 A5 JP2008546390 A5 JP 2008546390A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nthi
- composition
- polypeptide
- sequence number
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 14
- 229920001184 polypeptide Polymers 0.000 claims 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims 13
- 102000004196 processed proteins & peptides Human genes 0.000 claims 13
- 208000015181 infectious disease Diseases 0.000 claims 7
- 239000012634 fragment Substances 0.000 claims 6
- 239000012472 biological sample Substances 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 210000000959 ear middle Anatomy 0.000 claims 4
- 230000028993 immune response Effects 0.000 claims 4
- 241000894006 Bacteria Species 0.000 claims 3
- 108091033319 polynucleotide Proteins 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 102000040430 polynucleotide Human genes 0.000 claims 3
- 101100431814 Escherichia coli (strain K12) yciB gene Proteins 0.000 claims 2
- 101150008329 LPPB gene Proteins 0.000 claims 2
- 108091034117 Oligonucleotide Proteins 0.000 claims 2
- 101100162215 Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) agmR gene Proteins 0.000 claims 2
- 101100399642 Salmonella paratyphi A (strain ATCC 9150 / SARB42) lpp3 gene Proteins 0.000 claims 2
- 101100007845 Stigmatella aurantiaca (strain DW4/3-1) cspA gene Proteins 0.000 claims 2
- 101100028273 Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) argF gene Proteins 0.000 claims 2
- 239000000074 antisense oligonucleotide Substances 0.000 claims 2
- 238000012230 antisense oligonucleotides Methods 0.000 claims 2
- 101150032882 arcB gene Proteins 0.000 claims 2
- 230000000903 blocking effect Effects 0.000 claims 2
- 101150058203 cspD gene Proteins 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 101150097706 glpR gene Proteins 0.000 claims 2
- 101150107671 hisB gene Proteins 0.000 claims 2
- 101150117117 ihfB gene Proteins 0.000 claims 2
- 101150008361 licC gene Proteins 0.000 claims 2
- 101150005075 lpp2 gene Proteins 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 101150039901 mukF gene Proteins 0.000 claims 2
- 101150048280 ocd gene Proteins 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 101150047781 ptcA gene Proteins 0.000 claims 2
- 101150034471 rbsC gene Proteins 0.000 claims 2
- 230000010076 replication Effects 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 101150055723 sapA gene Proteins 0.000 claims 2
- 150000003384 small molecules Chemical class 0.000 claims 2
- 101150107825 uxuA gene Proteins 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 206010036790 Productive cough Diseases 0.000 claims 1
- 208000022362 bacterial infectious disease Diseases 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 230000003111 delayed effect Effects 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 210000004880 lymph fluid Anatomy 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000003802 sputum Anatomy 0.000 claims 1
- 208000024794 sputum Diseases 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69121405P | 2005-06-16 | 2005-06-16 | |
| PCT/US2006/023428 WO2006138527A2 (en) | 2005-06-16 | 2006-06-15 | Genes of an otitis media isolate of nontypeable haemophilus influenzae |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012062469A Division JP2012120543A (ja) | 2005-06-16 | 2012-03-19 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008546390A JP2008546390A (ja) | 2008-12-25 |
| JP2008546390A5 true JP2008546390A5 (https=) | 2009-07-02 |
Family
ID=37057493
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008517126A Pending JP2008546390A (ja) | 2005-06-16 | 2006-06-15 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2012062469A Pending JP2012120543A (ja) | 2005-06-16 | 2012-03-19 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2014095656A Pending JP2014147397A (ja) | 2005-06-16 | 2014-05-07 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2015224493A Pending JP2016054739A (ja) | 2005-06-16 | 2015-11-17 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2017000108A Pending JP2017074071A (ja) | 2005-06-16 | 2017-01-04 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012062469A Pending JP2012120543A (ja) | 2005-06-16 | 2012-03-19 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2014095656A Pending JP2014147397A (ja) | 2005-06-16 | 2014-05-07 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2015224493A Pending JP2016054739A (ja) | 2005-06-16 | 2015-11-17 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| JP2017000108A Pending JP2017074071A (ja) | 2005-06-16 | 2017-01-04 | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
Country Status (5)
| Country | Link |
|---|---|
| US (5) | US8283114B2 (https=) |
| EP (3) | EP1899366A2 (https=) |
| JP (5) | JP2008546390A (https=) |
| CA (2) | CA2871088A1 (https=) |
| WO (1) | WO2006138527A2 (https=) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| EP1871888A4 (en) * | 2005-03-30 | 2013-08-21 | Novartis Vaccines & Diagnostic | HAEMOPHILUS INFLUENZAE OF TYPE B |
| US8785130B2 (en) * | 2005-07-07 | 2014-07-22 | Bio-Id Diagnostic Inc. | Use of markers including nucleotide sequence based codes to monitor methods of detection and identification of genetic material |
| US9132183B2 (en) * | 2007-03-09 | 2015-09-15 | Newport Laboratories | Modified live (JMSO strain) Haemophilus parasuis vaccine |
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| EP2405938A2 (en) * | 2009-02-13 | 2012-01-18 | Intercell AG | Nontypable haemophilus influenzae antigens |
| KR101334981B1 (ko) * | 2010-06-10 | 2013-12-02 | 한국과학기술원 | 탄화수소 생성능을 가지는 변이 미생물 및 이를 이용한 탄화수소의 제조방법 |
| EP3567121B1 (en) | 2011-01-17 | 2023-08-30 | Life Technologies Corporation | Workflow for detection of ligands using nucleic acids |
| ES2645953T3 (es) | 2011-01-17 | 2017-12-11 | Life Technologies Corporation | Ligamiento enzimático de ácidos nucleicos |
| US20120276145A1 (en) * | 2011-03-28 | 2012-11-01 | House Research Institute | Extracellular matrix proteins from haemophilus influenzae biofilms: targets for therapeutic or diagnostic use |
| SG194886A1 (en) * | 2011-05-11 | 2013-12-30 | Riesbeck Healthcare Sweden Ab | Protein f - a novel haemophilus influenzae adhesin with laminin and vitronectin binding properties |
| RU2727476C2 (ru) * | 2012-04-26 | 2020-07-21 | Новартис Аг | Антигены и антигенные композиции |
| WO2014138748A1 (en) | 2013-03-08 | 2014-09-12 | Research Institute At Nationwide Children's Hospital | Transcutaneous dosage formulation |
| US9052314B2 (en) | 2013-03-14 | 2015-06-09 | Silver Lake Research Corporation | Biomarkers for detecting the presence of bacteria |
| US11274144B2 (en) | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
| US11248040B2 (en) | 2013-09-26 | 2022-02-15 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| US9580758B2 (en) | 2013-11-12 | 2017-02-28 | Luc Montagnier | System and method for the detection and treatment of infection by a microbial agent associated with HIV infection |
| JP6754694B2 (ja) * | 2014-03-06 | 2020-09-16 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | プロバイオティクス製剤および使用のための方法 |
| US10624934B2 (en) | 2014-03-06 | 2020-04-21 | Research Institute At Nationwide Children's Hospital | Prebiotic formulations |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| EP3307307A4 (en) * | 2015-06-09 | 2019-05-01 | The Board of Regents of the University of Oklahoma | COMPOSITIONS AND TREATMENTS FOR HAEMOPHILUS INFLUENZAE |
| WO2017023863A1 (en) | 2015-07-31 | 2017-02-09 | Research Institute At Nationwide Children's Hospital | Peptides and antibodies for the removal of biofilms |
| CN106567949A (zh) * | 2015-10-12 | 2017-04-19 | 海南广天恒科技发展有限公司 | 燃气阀专用限流装置 |
| EP3365027B1 (en) | 2015-10-14 | 2022-03-30 | Research Institute at Nationwide Children's Hospital | Hu specific antibodies and their use in inhibiting biofilm |
| JP2019522675A (ja) * | 2016-04-27 | 2019-08-15 | ▲拝▼西欧斯（北京）生物技▲術▼有限公司 | 興奮製神経毒性に関連した損傷の治療方法 |
| US11299751B2 (en) | 2016-04-29 | 2022-04-12 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| EP3448874A4 (en) | 2016-04-29 | 2020-04-22 | Voyager Therapeutics, Inc. | COMPOSITIONS FOR TREATING A DISEASE |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11564982B2 (en) | 2017-01-04 | 2023-01-31 | Research Institute At Nationwide Children's Hospital | DNABII vaccines and antibodies with enhanced activity |
| JP7661008B2 (ja) | 2017-01-04 | 2025-04-14 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | バイオフィルム関連障害の処置のための抗体断片 |
| CN111315287A (zh) * | 2017-05-18 | 2020-06-19 | 纽若蒂埃克斯有限公司 | 前庭声学信号处理 |
| CN107478627B (zh) * | 2017-08-30 | 2019-09-10 | 温州大学激光与光电智能制造研究院 | 基于荧光纤维丝示踪的壁湍流时空演化过程检测方法 |
| AU2019354829B2 (en) | 2018-10-05 | 2025-04-17 | Research Institute At Nationwide Children's Hospital | Hmgb1 protein derivatives for the removal of biofilms |
| EP3870154A4 (en) | 2018-10-22 | 2022-07-27 | Research Institute at Nationwide Children's Hospital | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF ANTIBIOTIC-INDUCED PATHOLOGIES USING PROBIOTICS IN BIOFILM STATE |
| WO2020174044A1 (en) * | 2019-02-27 | 2020-09-03 | Evaxion Biotech Aps | Vaccines targeting h. influenzae |
| CN111693691B (zh) * | 2019-03-14 | 2023-09-05 | 天津华科泰生物技术有限公司 | 一种基于卟啉结构的聚合物标签 |
| EP3979830B1 (en) | 2019-06-03 | 2025-11-26 | Research Institute at Nationwide Children's Hospital | Formulations for the treatment of neurodevelopmental deficiencies induced by necrotizing enterocolitis |
| CN112575041B (zh) * | 2019-09-30 | 2022-12-13 | 江南大学 | 一种混合碳源高效发酵生产phb的工程菌及其应用 |
| US11624734B2 (en) * | 2020-06-29 | 2023-04-11 | Waters Technologies Corporation | Chromatographic dimension selection in multidimensional liquid chromatography |
| CN112808285B (zh) * | 2021-01-14 | 2023-08-04 | 武汉科技大学 | 一种非均相类芬顿催化剂及其制备方法和应用 |
| CN114574456B (zh) * | 2022-03-18 | 2022-08-12 | 华南理工大学 | 一种亚硝酸盐还原酶突变体及其编码基因和应用 |
| CN120775878A (zh) * | 2025-07-04 | 2025-10-14 | 华中农业大学 | 一种副猪革拉瑟氏菌高效转座突变系统及其构建方法与应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996033276A1 (en) * | 1995-04-21 | 1996-10-24 | Human Genome Sciences, Inc. | NUCLEOTIDE SEQUENCE OF THE HAEMOPHILUS INFLUENZAE Rd GENOME, FRAGMENTS THEREOF, AND USES THEREOF |
| DE19728833A1 (de) | 1997-07-05 | 1999-01-07 | Bayer Ag | Verfahren zur Beseitigung von Oberflächengewässer verschmutzenden organischen Flüssigkeiten |
| CA2671261A1 (en) | 1997-11-06 | 1999-05-20 | Novartis Vaccines And Diagnostics S.R.L. | Neisserial antigens |
| EP1149164A2 (en) | 1999-01-22 | 2001-10-31 | SmithKline Beecham Biologics SA | Neisseria meningitidis polypeptides |
| US6605709B1 (en) * | 1999-04-09 | 2003-08-12 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Proteus mirabilis for diagnostics and therapeutics |
| GB0026002D0 (en) | 2000-10-24 | 2000-12-13 | Smithkline Beecham Biolog | Novel compounds |
| CA2796381A1 (en) * | 2003-03-06 | 2004-09-16 | Children's Hospital, Inc. | Genes of an otitis media isolate of nontypeable haemophilus influenzae |
| WO2004087749A2 (en) * | 2003-03-27 | 2004-10-14 | Children's Hospital, Inc. | Nontypeable haemophilus influenzae virulence factors |
| GB0410866D0 (en) * | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
-
2006
- 2006-06-15 CA CA2871088A patent/CA2871088A1/en not_active Abandoned
- 2006-06-15 EP EP06773314A patent/EP1899366A2/en not_active Withdrawn
- 2006-06-15 WO PCT/US2006/023428 patent/WO2006138527A2/en not_active Ceased
- 2006-06-15 US US11/917,368 patent/US8283114B2/en not_active Expired - Fee Related
- 2006-06-15 EP EP10176053A patent/EP2343312A1/en not_active Withdrawn
- 2006-06-15 JP JP2008517126A patent/JP2008546390A/ja active Pending
- 2006-06-15 EP EP08022435A patent/EP2070945A1/en not_active Withdrawn
- 2006-06-15 CA CA002612240A patent/CA2612240A1/en not_active Abandoned
-
2012
- 2012-03-19 JP JP2012062469A patent/JP2012120543A/ja active Pending
- 2012-09-12 US US13/612,176 patent/US8652773B2/en not_active Expired - Fee Related
-
2014
- 2014-01-09 US US14/151,227 patent/US9034642B2/en not_active Expired - Fee Related
- 2014-05-07 JP JP2014095656A patent/JP2014147397A/ja active Pending
-
2015
- 2015-04-15 US US14/687,548 patent/US20150218231A1/en not_active Abandoned
- 2015-11-17 JP JP2015224493A patent/JP2016054739A/ja active Pending
-
2016
- 2016-06-09 US US15/177,584 patent/US20160289278A1/en not_active Abandoned
-
2017
- 2017-01-04 JP JP2017000108A patent/JP2017074071A/ja active Pending
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