JP2008545753A5 - - Google Patents
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- Publication number
- JP2008545753A5 JP2008545753A5 JP2008514858A JP2008514858A JP2008545753A5 JP 2008545753 A5 JP2008545753 A5 JP 2008545753A5 JP 2008514858 A JP2008514858 A JP 2008514858A JP 2008514858 A JP2008514858 A JP 2008514858A JP 2008545753 A5 JP2008545753 A5 JP 2008545753A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- growth factor
- composition according
- monoclonal antibody
- nrg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68711805P | 2005-06-02 | 2005-06-02 | |
| US75109205P | 2005-12-15 | 2005-12-15 | |
| PCT/US2006/021293 WO2006130773A2 (en) | 2005-06-02 | 2006-06-01 | Methods of treating brain tumors with antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013002317A Division JP2013136580A (ja) | 2005-06-02 | 2013-01-10 | 抗体で脳腫瘍を処置する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008545753A JP2008545753A (ja) | 2008-12-18 |
| JP2008545753A5 true JP2008545753A5 (https=) | 2009-05-07 |
Family
ID=37482322
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008514858A Pending JP2008545753A (ja) | 2005-06-02 | 2006-06-01 | 抗体で脳腫瘍を処置する方法 |
| JP2013002317A Pending JP2013136580A (ja) | 2005-06-02 | 2013-01-10 | 抗体で脳腫瘍を処置する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013002317A Pending JP2013136580A (ja) | 2005-06-02 | 2013-01-10 | 抗体で脳腫瘍を処置する方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20070036797A1 (https=) |
| EP (1) | EP1885400A4 (https=) |
| JP (2) | JP2008545753A (https=) |
| KR (1) | KR20080026562A (https=) |
| AU (1) | AU2006252419B2 (https=) |
| BR (1) | BRPI0611009A2 (https=) |
| CA (1) | CA2607699A1 (https=) |
| CR (1) | CR9512A (https=) |
| IL (1) | IL187318A0 (https=) |
| MA (1) | MA29570B1 (https=) |
| MX (1) | MX2007015056A (https=) |
| NO (1) | NO20080012L (https=) |
| RU (1) | RU2007146986A (https=) |
| WO (1) | WO2006130773A2 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040208876A1 (en) * | 2003-04-18 | 2004-10-21 | Kim Kyung Jin | Monoclonal antibodies to hepatocyte growth factor |
| CA2623236A1 (en) | 2005-09-26 | 2007-04-05 | Medarex, Inc. | Human monoclonal antibodies to cd70 |
| AR059922A1 (es) | 2006-04-01 | 2008-05-07 | Galaxy Biotech Llc | Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos |
| AR061171A1 (es) | 2006-06-02 | 2008-08-06 | Aveo Pharmaceuticals Inc | Proteinas de union al factor de crecimiento de hepatocitos (fch) |
| AR061170A1 (es) | 2006-06-02 | 2008-08-06 | Aveo Pharmaceuticals Inc | Proteinas que se unen con el factor de crecimiento de hepatocitos (hgf) |
| EA018260B1 (ru) | 2006-09-29 | 2013-06-28 | Онкомед Фармасьютикалз, Инк. | Антитела к дельта-подобному лиганду 4 человека и их применение |
| KR20090088946A (ko) * | 2006-12-14 | 2009-08-20 | 메다렉스, 인코포레이티드 | 씨디70에 결합하는 인간 항체 및 이의 용도 |
| WO2009027332A1 (en) * | 2007-08-24 | 2009-03-05 | Novartis Ag | A modulator of nrg1 for treatment of respiratory disorders |
| TW200948380A (en) * | 2008-04-11 | 2009-12-01 | Galaxy Biotech Llc | Combination of HGF inhibitor and PTEN agonist to treat cancer |
| US20110217294A1 (en) * | 2008-04-11 | 2011-09-08 | Daniel Fults | Combination of hgf inhibitor and hedgehog inhibitor to treat cancer |
| JP5972573B2 (ja) * | 2008-05-29 | 2016-08-17 | ギャラクシー バイオテック， エルエルシー | 塩基性線維芽細胞成長因子に対するモノクローナル抗体 |
| US20120052064A1 (en) | 2009-04-17 | 2012-03-01 | Yuuki Ito | Anti-hgf antibody combinational cancer therapies |
| ES2700450T3 (es) | 2009-10-16 | 2019-02-15 | Oncomed Pharm Inc | Combinación terapéutica y uso de anticuerpos antagonistas de DLL4 y agentes antihipertensores |
| DK2536748T3 (da) * | 2010-02-18 | 2014-10-13 | Genentech Inc | Neuregulin-antagonister og anvendelse deraf ved behandling af kræft |
| RU2439160C1 (ru) * | 2010-06-25 | 2012-01-10 | Государственное общеобразовательное учреждение высшего профессионального образования "Российский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО РГМУ Росздрава) | Способ получения моноклональных антител к аблюминальному мембранному антигену церебральных эндотелиоцитов |
| US20130315895A1 (en) * | 2010-07-01 | 2013-11-28 | Takeda Pharmaceutical Company Limited | COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET |
| US8551479B2 (en) | 2010-09-10 | 2013-10-08 | Oncomed Pharmaceuticals, Inc. | Methods for treating melanoma |
| JP6190723B2 (ja) | 2010-12-01 | 2017-08-30 | アルダーバイオ ホールディングス エルエルシー | 抗ｎｇｆ組成物およびその使用 |
| US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
| US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
| US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
| US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
| US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
| LT3485903T (lt) | 2011-09-23 | 2023-02-27 | Mereo Biopharma 5, Inc. | Vegf/ dll4 surišantys agentai ir jų panaudojimas |
| US9599620B2 (en) | 2012-10-31 | 2017-03-21 | Oncomed Pharmaceuticals, Inc. | Methods and monitoring of treatment with a DLL4 antagonist |
| WO2016070051A2 (en) | 2014-10-31 | 2016-05-06 | Oncomed Pharmaceuticals, Inc. | Combination therapy for treatment of disease |
| EP3353204B1 (en) | 2015-09-23 | 2023-10-18 | Mereo BioPharma 5, Inc. | Bi-specific anti-vegf/dll4 antibody for use in treating platinum-resistant ovarian cancer |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2564486B2 (ja) * | 1986-07-14 | 1996-12-18 | 修治 橋本 | 肝細胞増殖因子 |
| US6498144B1 (en) * | 1993-10-18 | 2002-12-24 | North Shore - Long Island Jewish Research Institute | Use of scatter factor to enhance angiogenesis |
| US5837676A (en) * | 1993-10-18 | 1998-11-17 | Long Island Jewish Medical Center | Use of scatter factor to enhance angiogenesis |
| US5707624A (en) * | 1994-06-03 | 1998-01-13 | The Regents Of The University Of Michigan | Treatment of Kaposi's sarcoma by inhibition of scatter factor |
| US6214344B1 (en) * | 1995-06-02 | 2001-04-10 | Genetech, Inc. | Hepatocyte growth factor receptor antagonists and uses thereof |
| US5686292A (en) * | 1995-06-02 | 1997-11-11 | Genentech, Inc. | Hepatocyte growth factor receptor antagonist antibodies and uses thereof |
| US5646036A (en) * | 1995-06-02 | 1997-07-08 | Genentech, Inc. | Nucleic acids encoding hepatocyte growth factor receptor antagonist antibodies |
| IL127558A0 (en) * | 1996-07-03 | 1999-10-28 | Genentech Inc | Hepatocyte growth factor receptor agonists and uses thereof |
| AU2003270118A1 (en) * | 2002-08-30 | 2004-03-19 | F. Hoffmann-La Roche Ag | Scatter factor/hepatocyte growth factor antagonist nk4 for the treatment of glioma |
| US7220410B2 (en) * | 2003-04-18 | 2007-05-22 | Galaxy Biotech, Llc | Monoclonal antibodies to hepatocyte growth factor |
| US20040208876A1 (en) * | 2003-04-18 | 2004-10-21 | Kim Kyung Jin | Monoclonal antibodies to hepatocyte growth factor |
| KR101254371B1 (ko) * | 2003-07-18 | 2013-05-02 | 암젠 프레몬트 인코포레이티드 | 간세포 성장인자에 결합하는 분리된 항체 |
| PT2213661E (pt) * | 2003-09-26 | 2011-12-15 | Exelixis Inc | Moduladores de c-met e métodos de uso |
| CA2572331A1 (en) * | 2004-07-02 | 2006-02-09 | Exelixis, Inc. | C-met modulators and method of use |
| WO2007056523A2 (en) * | 2005-11-08 | 2007-05-18 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Methods for diagnosing and monitoring the progression of cancer |
| AR059922A1 (es) * | 2006-04-01 | 2008-05-07 | Galaxy Biotech Llc | Anticuerpos monoclonales humanizados para el factor de crecimiento de hepatocitos |
| CL2009000843A1 (es) * | 2008-04-11 | 2009-07-24 | Galaxy Biotech Llc | Metodo para tratar cancer en un paciente que comprende la administracion de un primer agente que es inhibidor de factor de crecimiento de hepatocito (hgf) en combinacion con un segundo agente que es inhibidor de una ruta de senalizacion celular diferente de la ruta hgf/cmet. |
| US20110217294A1 (en) * | 2008-04-11 | 2011-09-08 | Daniel Fults | Combination of hgf inhibitor and hedgehog inhibitor to treat cancer |
-
2006
- 2006-06-01 EP EP06771847A patent/EP1885400A4/en not_active Withdrawn
- 2006-06-01 MX MX2007015056A patent/MX2007015056A/es not_active Application Discontinuation
- 2006-06-01 CA CA002607699A patent/CA2607699A1/en not_active Abandoned
- 2006-06-01 US US11/446,045 patent/US20070036797A1/en not_active Abandoned
- 2006-06-01 BR BRPI0611009-6A patent/BRPI0611009A2/pt not_active IP Right Cessation
- 2006-06-01 KR KR1020077030521A patent/KR20080026562A/ko not_active Withdrawn
- 2006-06-01 WO PCT/US2006/021293 patent/WO2006130773A2/en not_active Ceased
- 2006-06-01 AU AU2006252419A patent/AU2006252419B2/en not_active Ceased
- 2006-06-01 JP JP2008514858A patent/JP2008545753A/ja active Pending
- 2006-06-01 RU RU2007146986/14A patent/RU2007146986A/ru not_active Application Discontinuation
-
2007
- 2007-11-12 IL IL187318A patent/IL187318A0/en unknown
- 2007-11-12 CR CR9512A patent/CR9512A/es not_active Application Discontinuation
- 2007-12-27 MA MA30523A patent/MA29570B1/fr unknown
-
2008
- 2008-01-02 NO NO20080012A patent/NO20080012L/no not_active Application Discontinuation
-
2010
- 2010-01-19 US US12/690,045 patent/US20100221250A1/en not_active Abandoned
-
2013
- 2013-01-10 JP JP2013002317A patent/JP2013136580A/ja active Pending
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