JP2008545659A - オリゴヌクレオチドを標識する化合物及び方法 - Google Patents
オリゴヌクレオチドを標識する化合物及び方法 Download PDFInfo
- Publication number
- JP2008545659A JP2008545659A JP2008512555A JP2008512555A JP2008545659A JP 2008545659 A JP2008545659 A JP 2008545659A JP 2008512555 A JP2008512555 A JP 2008512555A JP 2008512555 A JP2008512555 A JP 2008512555A JP 2008545659 A JP2008545659 A JP 2008545659A
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- Japan
- Prior art keywords
- group
- composition
- compound
- oligonucleotide
- pair
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 *c(c(*)c12)c(*)c(*)c1c([N+]([O-])=O)c(*)c(*)c2N Chemical compound *c(c(*)c12)c(*)c(*)c1c([N+]([O-])=O)c(*)c(*)c2N 0.000 description 3
- IMTFIITVIYDUHW-UHFFFAOYSA-N Cc(cc(c1c2cccc1)N)c2[N+]([O-])=O Chemical compound Cc(cc(c1c2cccc1)N)c2[N+]([O-])=O IMTFIITVIYDUHW-UHFFFAOYSA-N 0.000 description 1
- BVPJPRYNQHAOPQ-UHFFFAOYSA-N Nc(c1ccccc11)ccc1[N+]([O-])=O Chemical compound Nc(c1ccccc11)ccc1[N+]([O-])=O BVPJPRYNQHAOPQ-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
- C07C245/02—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides
- C07C245/06—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings
- C07C245/10—Azo compounds, i.e. compounds having the free valencies of —N=N— groups attached to different atoms, e.g. diazohydroxides with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings with nitrogen atoms of azo groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68327805P | 2005-05-20 | 2005-05-20 | |
PCT/US2006/019552 WO2006127507A2 (en) | 2005-05-20 | 2006-05-22 | Compounds and methods for labeling oligonucleotides |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2008545659A true JP2008545659A (ja) | 2008-12-18 |
Family
ID=37452651
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008512555A Pending JP2008545659A (ja) | 2005-05-20 | 2006-05-22 | オリゴヌクレオチドを標識する化合物及び方法 |
Country Status (6)
Families Citing this family (33)
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EP2085434A1 (en) * | 2008-01-11 | 2009-08-05 | Universita' Degli Studi di Firenze | Disperse dyes soluble in water |
PT2757091T (pt) * | 2008-04-01 | 2017-07-24 | Biosearch Tech Inc | Sondas de fluoróforo e supressor de fluorescência de ácido nucleico estabilizadas |
US9155471B2 (en) * | 2009-05-27 | 2015-10-13 | Lumicell, Inc'. | Methods and systems for spatially identifying abnormal cells |
KR101851117B1 (ko) | 2010-01-29 | 2018-04-23 | 마이크로닉스 인코포레이티드. | 샘플-투-앤서 마이크로유체 카트리지 |
US20120108799A1 (en) | 2010-09-07 | 2012-05-03 | Integrated Dna Technologies, Inc. | Modifications for Antisense Compounds |
US9506057B2 (en) | 2010-03-26 | 2016-11-29 | Integrated Dna Technologies, Inc. | Modifications for antisense compounds |
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US9314304B2 (en) | 2010-12-08 | 2016-04-19 | Lumicell, Inc. | Methods and system for image guided cell ablation with microscopic resolution |
WO2013033436A1 (en) * | 2011-09-01 | 2013-03-07 | University Of Iowa Research Foundation | Oligonucleotide-based probes for detection of bacterial nucleases |
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WO2014030066A2 (en) | 2012-08-22 | 2014-02-27 | Bernitz Mats Nilsson | Methods for identifying nucleic acid sequences |
JP2016509206A (ja) | 2012-12-21 | 2016-03-24 | マイクロニクス, インコーポレイテッド | 携帯型蛍光検出システムおよびマイクロアッセイカートリッジ |
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JP6498125B2 (ja) | 2012-12-21 | 2019-04-10 | マイクロニクス, インコーポレイテッド | 流体回路および関連する製造方法 |
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KR20160037834A (ko) | 2013-03-14 | 2016-04-06 | 루미셀, 아이엔씨. | 의료 이미징 장치 및 사용 방법 |
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EP2994543B1 (en) | 2013-05-07 | 2018-08-15 | Micronics, Inc. | Device for preparation and analysis of nucleic acids |
WO2014182831A1 (en) | 2013-05-07 | 2014-11-13 | Micronics, Inc. | Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions |
WO2015120406A1 (en) | 2014-02-07 | 2015-08-13 | University Of Iowa Research Foundation | Oligonucleotide-based probes and methods for detection of microbes |
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CN116096884A (zh) | 2020-04-22 | 2023-05-09 | 哈佛大学校长及研究员协会 | 用于检测核酸的恒温方法、组合物、试剂盒和系统 |
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-
2006
- 2006-05-22 CA CA002601554A patent/CA2601554A1/en not_active Abandoned
- 2006-05-22 US US11/438,606 patent/US7476735B2/en active Active
- 2006-05-22 WO PCT/US2006/019552 patent/WO2006127507A2/en active Application Filing
- 2006-05-22 EP EP06770717A patent/EP1907560B1/en not_active Not-in-force
- 2006-05-22 JP JP2008512555A patent/JP2008545659A/ja active Pending
- 2006-05-22 AU AU2006251637A patent/AU2006251637B2/en not_active Ceased
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2009
- 2009-01-12 US US12/352,125 patent/US7605243B2/en not_active Expired - Fee Related
- 2009-08-04 US US12/535,220 patent/US7645872B2/en not_active Expired - Fee Related
- 2009-11-23 US US12/623,811 patent/US7803936B2/en active Active
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2010
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2011
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US7476735B2 (en) | 2009-01-13 |
AU2006251637A1 (en) | 2006-11-30 |
CA2601554A1 (en) | 2006-11-30 |
EP1907560A4 (en) | 2011-04-13 |
WO2006127507A3 (en) | 2007-04-05 |
US8258276B2 (en) | 2012-09-04 |
US8030460B2 (en) | 2011-10-04 |
WO2006127507A2 (en) | 2006-11-30 |
US20060263816A1 (en) | 2006-11-23 |
US20090118482A1 (en) | 2009-05-07 |
US7605243B2 (en) | 2009-10-20 |
US20110319606A1 (en) | 2011-12-29 |
EP1907560A2 (en) | 2008-04-09 |
EP1907560B1 (en) | 2013-01-23 |
US20100076181A1 (en) | 2010-03-25 |
AU2006251637B2 (en) | 2012-06-14 |
US20090299041A1 (en) | 2009-12-03 |
US7803936B2 (en) | 2010-09-28 |
US20100298554A1 (en) | 2010-11-25 |
US7645872B2 (en) | 2010-01-12 |
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