JP2008545426A - 高親和性メラン−at細胞レセプター - Google Patents

高親和性メラン−at細胞レセプター Download PDF

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Publication number
JP2008545426A
JP2008545426A JP2008514187A JP2008514187A JP2008545426A JP 2008545426 A JP2008545426 A JP 2008545426A JP 2008514187 A JP2008514187 A JP 2008514187A JP 2008514187 A JP2008514187 A JP 2008514187A JP 2008545426 A JP2008545426 A JP 2008545426A
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JP
Japan
Prior art keywords
tcr
seq
chain
chain variable
variable region
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Pending
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JP2008514187A
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English (en)
Japanese (ja)
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JP2008545426A5 (https=
Inventor
ヤコブセン,ベント,カルステン
リッディ,ナサニエル,ロス
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Medigene Ltd
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Medigene Ltd
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Publication date
Application filed by Medigene Ltd filed Critical Medigene Ltd
Publication of JP2008545426A publication Critical patent/JP2008545426A/ja
Publication of JP2008545426A5 publication Critical patent/JP2008545426A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
JP2008514187A 2005-06-01 2006-05-31 高親和性メラン−at細胞レセプター Pending JP2008545426A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0511124.0A GB0511124D0 (en) 2005-06-01 2005-06-01 High affinity melan-a t cell receptors
PCT/GB2006/001980 WO2006129085A2 (en) 2005-06-01 2006-05-31 High affinity melan-a t cell receptors

Publications (2)

Publication Number Publication Date
JP2008545426A true JP2008545426A (ja) 2008-12-18
JP2008545426A5 JP2008545426A5 (https=) 2009-07-09

Family

ID=34834931

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008514187A Pending JP2008545426A (ja) 2005-06-01 2006-05-31 高親和性メラン−at細胞レセプター

Country Status (12)

Country Link
US (1) US8217144B2 (https=)
EP (1) EP1893642A2 (https=)
JP (1) JP2008545426A (https=)
CN (1) CN101189261B (https=)
AU (1) AU2006253941B2 (https=)
BR (1) BRPI0611326A2 (https=)
CA (1) CA2610786A1 (https=)
EA (1) EA012507B1 (https=)
GB (1) GB0511124D0 (https=)
MX (1) MX2007014919A (https=)
WO (1) WO2006129085A2 (https=)
ZA (1) ZA200710009B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018527954A (ja) * 2015-09-15 2018-09-27 アダプティミューネ リミテッドAdaptimmune Limited Tcrライブラリ

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7994298B2 (en) 2004-09-24 2011-08-09 Trustees Of Dartmouth College Chimeric NK receptor and methods for treating cancer
US8088379B2 (en) * 2006-09-26 2012-01-03 The United States Of America As Represented By The Department Of Health And Human Services Modified T cell receptors and related materials and methods
EP2087000A2 (en) * 2006-09-29 2009-08-12 Immunocore Ltd. T cell therapies
US8119772B2 (en) 2006-09-29 2012-02-21 California Institute Of Technology MART-1 T cell receptors
GB0816096D0 (en) * 2008-09-04 2008-10-15 Medigene Ltd Diabetes t cell receptors
GB0911566D0 (en) 2009-07-03 2009-08-12 Immunocore Ltd T cell receptors
WO2011059836A2 (en) 2009-10-29 2011-05-19 Trustees Of Dartmouth College T cell receptor-deficient t cell compositions
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
US12492376B2 (en) 2009-10-29 2025-12-09 The Trustees Of Dartmouth College T-cell receptor-deficient T cell compositions
CA3080181A1 (en) * 2011-03-04 2012-09-13 Shire Human Genetic Therapies, Inc. Peptide linkers for polypeptide compositions and methods for using same
WO2013033626A2 (en) 2011-08-31 2013-03-07 Trustees Of Dartmouth College Nkp30 receptor targeted therapeutics
EP2844743B1 (en) 2012-05-03 2021-01-13 Fred Hutchinson Cancer Research Center Enhanced affinity t cell receptors and methods for making the same
WO2013169691A1 (en) 2012-05-07 2013-11-14 Trustees Of Dartmouth College Anti-b7-h6 antibody, fusion proteins, and methods of using the same
US9561266B2 (en) 2012-08-31 2017-02-07 University Of Virginia Patent Foundation Target peptides for immunotherapy and diagnostics
WO2014039675A2 (en) 2012-09-05 2014-03-13 University Of Virginia Patent Foundation Target peptides for colorectal cancer therapy and diagnostics
KR102415259B1 (ko) * 2013-11-22 2022-06-30 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 조작된 고-친화도의 인간 t 세포 수용체
EP3137100B1 (en) 2014-04-15 2023-12-20 University Of Virginia Patent Foundation Isolated t cell receptors and methods of use therefor
EP2944652A1 (en) * 2014-05-13 2015-11-18 Technische Universität München Glypican-3-specific T-cell receptors and their uses for immunotherapy of hepatocellular carcinoma
US10526391B2 (en) 2014-07-22 2020-01-07 The University Of Notre Dame Du Lac Molecular constructs and uses thereof
GB201417803D0 (en) * 2014-10-08 2014-11-19 Adaptimmune Ltd T cell receptors
GB201506642D0 (en) 2015-04-20 2015-06-03 Ucl Business Plc T cell receptor
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
GB201516277D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR libraries
US11827688B2 (en) 2016-06-02 2023-11-28 Immunocore Limited Dosing regimen for GP100-specific TCR—anti-CD3 SCFV fusion protein
GB201617714D0 (en) 2016-10-19 2016-11-30 Ucl Business Plc T Cell receptor
JP7037577B2 (ja) * 2017-03-15 2022-03-16 フレッド ハッチンソン キャンサー リサーチ センター 高親和性mage-a1特異的tcr及びその使用
WO2019004831A1 (en) * 2017-06-30 2019-01-03 Academisch Ziekenhuis Leiden (H.O.D.N. Leids Universitair Medisch Centrum) TREATMENT OF HEMATOLOGICAL MALIGNANCIES
WO2019069125A1 (en) 2017-10-06 2019-04-11 Oslo Universitetssykehus Hf CHIMERIC ANTIGEN RECEPTORS
CN112646024B (zh) * 2019-10-10 2023-03-24 香雪生命科学技术(广东)有限公司 一种识别kras突变的t细胞受体及其编码序列

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004044004A2 (en) * 2002-11-09 2004-05-27 Avidex Limited T cell receptor display

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL160359A0 (en) 2001-08-31 2004-07-25 Avidex Ltd Soluble t cell receptor
US7751825B2 (en) 2002-06-27 2010-07-06 Qualcomm Incorporated Controlling geographic location information of devices operating in wireless communication systems
CA2501870C (en) 2002-10-09 2013-07-02 Avidex Limited Single chain recombinant t cell receptors
EP1567553A2 (en) * 2002-12-03 2005-08-31 Avidex Ltd. Complexes of receptors
ATE417065T1 (de) * 2004-05-19 2008-12-15 Medigene Ltd Hochaffiner ny-eso-t-zellen-rezeptor
AU2005246073B2 (en) 2004-05-19 2010-10-28 Adaptimmune Limited Method of improving T cell receptors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004044004A2 (en) * 2002-11-09 2004-05-27 Avidex Limited T cell receptor display

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6011052937; Nat. Biotechnol. 23(3), 200503, 349-54 *
JPN6011052939; J. Immunol. 161, 1998, 6956-62 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018527954A (ja) * 2015-09-15 2018-09-27 アダプティミューネ リミテッドAdaptimmune Limited Tcrライブラリ

Also Published As

Publication number Publication date
WO2006129085A2 (en) 2006-12-07
US8217144B2 (en) 2012-07-10
EP1893642A2 (en) 2008-03-05
BRPI0611326A2 (pt) 2010-08-31
US20080292549A1 (en) 2008-11-27
CN101189261B (zh) 2012-12-05
WO2006129085A3 (en) 2007-02-01
EA200702677A1 (ru) 2008-06-30
GB0511124D0 (en) 2005-07-06
CA2610786A1 (en) 2006-12-07
EA012507B1 (ru) 2009-10-30
AU2006253941A2 (en) 2008-03-06
MX2007014919A (es) 2009-02-16
AU2006253941B2 (en) 2012-04-12
AU2006253941A1 (en) 2006-12-07
CN101189261A (zh) 2008-05-28
ZA200710009B (en) 2008-09-25

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