CA2610786A1 - High affinity melan-a t cell receptors - Google Patents

High affinity melan-a t cell receptors Download PDF

Info

Publication number
CA2610786A1
CA2610786A1 CA002610786A CA2610786A CA2610786A1 CA 2610786 A1 CA2610786 A1 CA 2610786A1 CA 002610786 A CA002610786 A CA 002610786A CA 2610786 A CA2610786 A CA 2610786A CA 2610786 A1 CA2610786 A1 CA 2610786A1
Authority
CA
Canada
Prior art keywords
tcr
seq
fwdarw
chain variable
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002610786A
Other languages
English (en)
French (fr)
Inventor
Bent Karsten Jakobsen
Nathaniel Ross Liddy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunocore Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2610786A1 publication Critical patent/CA2610786A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
CA002610786A 2005-06-01 2006-05-31 High affinity melan-a t cell receptors Abandoned CA2610786A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0511124.0A GB0511124D0 (en) 2005-06-01 2005-06-01 High affinity melan-a t cell receptors
GB0511124.0 2005-06-01
PCT/GB2006/001980 WO2006129085A2 (en) 2005-06-01 2006-05-31 High affinity melan-a t cell receptors

Publications (1)

Publication Number Publication Date
CA2610786A1 true CA2610786A1 (en) 2006-12-07

Family

ID=34834931

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002610786A Abandoned CA2610786A1 (en) 2005-06-01 2006-05-31 High affinity melan-a t cell receptors

Country Status (12)

Country Link
US (1) US8217144B2 (https=)
EP (1) EP1893642A2 (https=)
JP (1) JP2008545426A (https=)
CN (1) CN101189261B (https=)
AU (1) AU2006253941B2 (https=)
BR (1) BRPI0611326A2 (https=)
CA (1) CA2610786A1 (https=)
EA (1) EA012507B1 (https=)
GB (1) GB0511124D0 (https=)
MX (1) MX2007014919A (https=)
WO (1) WO2006129085A2 (https=)
ZA (1) ZA200710009B (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7994298B2 (en) 2004-09-24 2011-08-09 Trustees Of Dartmouth College Chimeric NK receptor and methods for treating cancer
US8088379B2 (en) * 2006-09-26 2012-01-03 The United States Of America As Represented By The Department Of Health And Human Services Modified T cell receptors and related materials and methods
EP2087000A2 (en) * 2006-09-29 2009-08-12 Immunocore Ltd. T cell therapies
US8119772B2 (en) 2006-09-29 2012-02-21 California Institute Of Technology MART-1 T cell receptors
GB0816096D0 (en) * 2008-09-04 2008-10-15 Medigene Ltd Diabetes t cell receptors
GB0911566D0 (en) 2009-07-03 2009-08-12 Immunocore Ltd T cell receptors
WO2011059836A2 (en) 2009-10-29 2011-05-19 Trustees Of Dartmouth College T cell receptor-deficient t cell compositions
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
US12492376B2 (en) 2009-10-29 2025-12-09 The Trustees Of Dartmouth College T-cell receptor-deficient T cell compositions
CA3080181A1 (en) * 2011-03-04 2012-09-13 Shire Human Genetic Therapies, Inc. Peptide linkers for polypeptide compositions and methods for using same
WO2013033626A2 (en) 2011-08-31 2013-03-07 Trustees Of Dartmouth College Nkp30 receptor targeted therapeutics
EP2844743B1 (en) 2012-05-03 2021-01-13 Fred Hutchinson Cancer Research Center Enhanced affinity t cell receptors and methods for making the same
WO2013169691A1 (en) 2012-05-07 2013-11-14 Trustees Of Dartmouth College Anti-b7-h6 antibody, fusion proteins, and methods of using the same
US9561266B2 (en) 2012-08-31 2017-02-07 University Of Virginia Patent Foundation Target peptides for immunotherapy and diagnostics
WO2014039675A2 (en) 2012-09-05 2014-03-13 University Of Virginia Patent Foundation Target peptides for colorectal cancer therapy and diagnostics
KR102415259B1 (ko) * 2013-11-22 2022-06-30 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 조작된 고-친화도의 인간 t 세포 수용체
EP3137100B1 (en) 2014-04-15 2023-12-20 University Of Virginia Patent Foundation Isolated t cell receptors and methods of use therefor
EP2944652A1 (en) * 2014-05-13 2015-11-18 Technische Universität München Glypican-3-specific T-cell receptors and their uses for immunotherapy of hepatocellular carcinoma
US10526391B2 (en) 2014-07-22 2020-01-07 The University Of Notre Dame Du Lac Molecular constructs and uses thereof
GB201417803D0 (en) * 2014-10-08 2014-11-19 Adaptimmune Ltd T cell receptors
GB201506642D0 (en) 2015-04-20 2015-06-03 Ucl Business Plc T cell receptor
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
GB201516272D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
GB201516277D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR libraries
US11827688B2 (en) 2016-06-02 2023-11-28 Immunocore Limited Dosing regimen for GP100-specific TCR—anti-CD3 SCFV fusion protein
GB201617714D0 (en) 2016-10-19 2016-11-30 Ucl Business Plc T Cell receptor
JP7037577B2 (ja) * 2017-03-15 2022-03-16 フレッド ハッチンソン キャンサー リサーチ センター 高親和性mage-a1特異的tcr及びその使用
WO2019004831A1 (en) * 2017-06-30 2019-01-03 Academisch Ziekenhuis Leiden (H.O.D.N. Leids Universitair Medisch Centrum) TREATMENT OF HEMATOLOGICAL MALIGNANCIES
WO2019069125A1 (en) 2017-10-06 2019-04-11 Oslo Universitetssykehus Hf CHIMERIC ANTIGEN RECEPTORS
CN112646024B (zh) * 2019-10-10 2023-03-24 香雪生命科学技术(广东)有限公司 一种识别kras突变的t细胞受体及其编码序列

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL160359A0 (en) 2001-08-31 2004-07-25 Avidex Ltd Soluble t cell receptor
US7751825B2 (en) 2002-06-27 2010-07-06 Qualcomm Incorporated Controlling geographic location information of devices operating in wireless communication systems
CA2501870C (en) 2002-10-09 2013-07-02 Avidex Limited Single chain recombinant t cell receptors
PT1558643E (pt) * 2002-11-09 2009-08-24 Immunocore Ltd Apresentação de um receptor das células t
EP1567553A2 (en) * 2002-12-03 2005-08-31 Avidex Ltd. Complexes of receptors
ATE417065T1 (de) * 2004-05-19 2008-12-15 Medigene Ltd Hochaffiner ny-eso-t-zellen-rezeptor
AU2005246073B2 (en) 2004-05-19 2010-10-28 Adaptimmune Limited Method of improving T cell receptors

Also Published As

Publication number Publication date
WO2006129085A2 (en) 2006-12-07
US8217144B2 (en) 2012-07-10
EP1893642A2 (en) 2008-03-05
BRPI0611326A2 (pt) 2010-08-31
US20080292549A1 (en) 2008-11-27
JP2008545426A (ja) 2008-12-18
CN101189261B (zh) 2012-12-05
WO2006129085A3 (en) 2007-02-01
EA200702677A1 (ru) 2008-06-30
GB0511124D0 (en) 2005-07-06
EA012507B1 (ru) 2009-10-30
AU2006253941A2 (en) 2008-03-06
MX2007014919A (es) 2009-02-16
AU2006253941B2 (en) 2012-04-12
AU2006253941A1 (en) 2006-12-07
CN101189261A (zh) 2008-05-28
ZA200710009B (en) 2008-09-25

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20140822