CA2610786A1 - High affinity melan-a t cell receptors - Google Patents

High affinity melan-a t cell receptors Download PDF

Info

Publication number
CA2610786A1
CA2610786A1 CA002610786A CA2610786A CA2610786A1 CA 2610786 A1 CA2610786 A1 CA 2610786A1 CA 002610786 A CA002610786 A CA 002610786A CA 2610786 A CA2610786 A CA 2610786A CA 2610786 A1 CA2610786 A1 CA 2610786A1
Authority
CA
Canada
Prior art keywords
tcr
seq
fwdarw
chain variable
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002610786A
Other languages
English (en)
French (fr)
Inventor
Bent Karsten Jakobsen
Nathaniel Ross Liddy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunocore Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2610786A1 publication Critical patent/CA2610786A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
CA002610786A 2005-06-01 2006-05-31 High affinity melan-a t cell receptors Abandoned CA2610786A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0511124.0A GB0511124D0 (en) 2005-06-01 2005-06-01 High affinity melan-a t cell receptors
GB0511124.0 2005-06-01
PCT/GB2006/001980 WO2006129085A2 (en) 2005-06-01 2006-05-31 High affinity melan-a t cell receptors

Publications (1)

Publication Number Publication Date
CA2610786A1 true CA2610786A1 (en) 2006-12-07

Family

ID=34834931

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002610786A Abandoned CA2610786A1 (en) 2005-06-01 2006-05-31 High affinity melan-a t cell receptors

Country Status (12)

Country Link
US (1) US8217144B2 (https=)
EP (1) EP1893642A2 (https=)
JP (1) JP2008545426A (https=)
CN (1) CN101189261B (https=)
AU (1) AU2006253941B2 (https=)
BR (1) BRPI0611326A2 (https=)
CA (1) CA2610786A1 (https=)
EA (1) EA012507B1 (https=)
GB (1) GB0511124D0 (https=)
MX (1) MX2007014919A (https=)
WO (1) WO2006129085A2 (https=)
ZA (1) ZA200710009B (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7994298B2 (en) 2004-09-24 2011-08-09 Trustees Of Dartmouth College Chimeric NK receptor and methods for treating cancer
WO2008039818A2 (en) * 2006-09-26 2008-04-03 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Modified t cell receptors and related materials and methods
WO2008042814A2 (en) * 2006-09-29 2008-04-10 California Institute Of Technology Mart-1 t cell receptors
EP2087000A2 (en) * 2006-09-29 2009-08-12 Immunocore Ltd. T cell therapies
GB0816096D0 (en) * 2008-09-04 2008-10-15 Medigene Ltd Diabetes t cell receptors
GB0911566D0 (en) 2009-07-03 2009-08-12 Immunocore Ltd T cell receptors
US12492376B2 (en) 2009-10-29 2025-12-09 The Trustees Of Dartmouth College T-cell receptor-deficient T cell compositions
WO2011059836A2 (en) 2009-10-29 2011-05-19 Trustees Of Dartmouth College T cell receptor-deficient t cell compositions
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
BR112013022557A2 (pt) * 2011-03-04 2017-08-01 Shire Human Genetic Therapies ligantes de peptídeo composições de polipeptídeo e métodos para uso dos mesmos
US9833476B2 (en) 2011-08-31 2017-12-05 The Trustees Of Dartmouth College NKP30 receptor targeted therapeutics
SG10201609210SA (en) * 2012-05-03 2016-12-29 Hutchinson Fred Cancer Res Enhanced affinity t cell receptors and methods for making the same
ES2719495T5 (en) 2012-05-07 2025-09-10 Dartmouth College Anti-b7-h6 antibody, fusion proteins, and methods of using the same
EP3718556A3 (en) 2012-08-31 2020-12-30 University Of Virginia Patent Foundation Target peptides for immunotherapy and diagnostics
EP4088737A3 (en) 2012-09-05 2023-02-08 University Of Virginia Patent Foundation Target peptides for colorectal cancer therapy and diagnostics
EP3071594A4 (en) * 2013-11-22 2017-05-03 The Board of Trustees of the University of Illionis Engineered high-affinity human t cell receptors
CA2945816A1 (en) 2014-04-15 2015-10-22 University Of Virginia Patent Foundation Isolated t cell receptors and methods of use therefor
EP2944652A1 (en) * 2014-05-13 2015-11-18 Technische Universität München Glypican-3-specific T-cell receptors and their uses for immunotherapy of hepatocellular carcinoma
WO2016014725A1 (en) * 2014-07-22 2016-01-28 The University Of Notre Dame Du Lac Molecular constructs and uses thereof
GB201417803D0 (en) * 2014-10-08 2014-11-19 Adaptimmune Ltd T cell receptors
GB201506642D0 (en) 2015-04-20 2015-06-03 Ucl Business Plc T cell receptor
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
GB201516277D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR libraries
GB201516272D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
WO2017208018A1 (en) 2016-06-02 2017-12-07 Immunocore Limited Dosing regimen for gp100-specific tcr - anti-cd3 scfv fusion protein
GB201617714D0 (en) 2016-10-19 2016-11-30 Ucl Business Plc T Cell receptor
MX2019010972A (es) * 2017-03-15 2019-12-02 Hutchinson Fred Cancer Res Receptores de linfocito t (tcr) específicos del antígeno asociado a melanoma 1 (mage-a1) de alta afinidad y usos de estos.
US11352389B2 (en) * 2017-06-30 2022-06-07 Academisch Ziekenhuis Leiden (H.O.D.N. Leids Universitair Medisch Centrum) Treatment of haematological malignancies
US20200308279A1 (en) 2017-10-06 2020-10-01 Oslo Universitetssykehus Hf Chimeric antigen receptors
CN112646024B (zh) * 2019-10-10 2023-03-24 香雪生命科学技术(广东)有限公司 一种识别kras突变的t细胞受体及其编码序列

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002321581C1 (en) 2001-08-31 2008-09-18 Adaptimmune Limited Soluble T cell receptor
US7751825B2 (en) 2002-06-27 2010-07-06 Qualcomm Incorporated Controlling geographic location information of devices operating in wireless communication systems
AU2003271904B2 (en) 2002-10-09 2009-03-05 Adaptimmune Limited Single chain recombinant T cell receptors
DE60327795D1 (de) * 2002-11-09 2009-07-09 Immunocore Ltd T zell rezeptor "display"
JP2006523437A (ja) * 2002-12-03 2006-10-19 アヴィデックス リミテッド レセプター複合体
DK1765860T3 (da) * 2004-05-19 2009-03-09 Immunocore Ltd Ny-ESO-T.cellereceptor med höj affinitet
NZ550815A (en) * 2004-05-19 2009-04-30 Immunocore Ltd Method of improving T cell receptors

Also Published As

Publication number Publication date
WO2006129085A2 (en) 2006-12-07
CN101189261B (zh) 2012-12-05
JP2008545426A (ja) 2008-12-18
EA200702677A1 (ru) 2008-06-30
AU2006253941A1 (en) 2006-12-07
MX2007014919A (es) 2009-02-16
WO2006129085A3 (en) 2007-02-01
US8217144B2 (en) 2012-07-10
ZA200710009B (en) 2008-09-25
GB0511124D0 (en) 2005-07-06
CN101189261A (zh) 2008-05-28
US20080292549A1 (en) 2008-11-27
AU2006253941B2 (en) 2012-04-12
EP1893642A2 (en) 2008-03-05
AU2006253941A2 (en) 2008-03-06
BRPI0611326A2 (pt) 2010-08-31
EA012507B1 (ru) 2009-10-30

Similar Documents

Publication Publication Date Title
US8217144B2 (en) High affinity Melan-A T cell receptors
US20210061878A1 (en) High affinity ny-eso t cell receptors
EP1885754B1 (en) T cell receptors which specifically bind to vygfvracl-hla-a24
CA2602463C (en) High affinity hiv t cell receptors
US8017730B2 (en) T cell receptors which specifically bind to VYGFVRACL-HLA-A24
JP5186209B2 (ja) テロメラーゼ高親和性t細胞受容体

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20140822