JP2008543853A - プラスグレルのための薬剤投与計画 - Google Patents

プラスグレルのための薬剤投与計画 Download PDF

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Publication number
JP2008543853A
JP2008543853A JP2008517022A JP2008517022A JP2008543853A JP 2008543853 A JP2008543853 A JP 2008543853A JP 2008517022 A JP2008517022 A JP 2008517022A JP 2008517022 A JP2008517022 A JP 2008517022A JP 2008543853 A JP2008543853 A JP 2008543853A
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JP
Japan
Prior art keywords
administration
prasugrel
compound
formula
equivalent
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Pending
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JP2008517022A
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English (en)
Japanese (ja)
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JP2008543853A5 (https=
Inventor
ジョン・トーマス・ブラント
ナギー・アルフォンス・ファリッド
ジョゼフ・アンソニー・ジャクボースキー
クリストファー・デイビッド・ペイン
ゴビンダ・ジャヤナト・ウィーラコディ
ケネス・ジョン・ウィンターズ
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イーライ リリー アンド カンパニー
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Publication of JP2008543853A publication Critical patent/JP2008543853A/ja
Publication of JP2008543853A5 publication Critical patent/JP2008543853A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4743—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2008517022A 2005-06-17 2006-06-13 プラスグレルのための薬剤投与計画 Pending JP2008543853A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69174005P 2005-06-17 2005-06-17
PCT/US2006/023006 WO2006138317A2 (en) 2005-06-17 2006-06-13 Dosage regimen for prasugrel

Publications (2)

Publication Number Publication Date
JP2008543853A true JP2008543853A (ja) 2008-12-04
JP2008543853A5 JP2008543853A5 (https=) 2009-07-30

Family

ID=37571073

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008517022A Pending JP2008543853A (ja) 2005-06-17 2006-06-13 プラスグレルのための薬剤投与計画

Country Status (18)

Country Link
US (1) US20090156632A1 (https=)
EP (1) EP1893205A4 (https=)
JP (1) JP2008543853A (https=)
KR (1) KR20080016647A (https=)
CN (1) CN101198329A (https=)
AU (1) AU2006259538A1 (https=)
BR (1) BRPI0612624A2 (https=)
CA (1) CA2612315A1 (https=)
EA (1) EA200800075A1 (https=)
EC (1) ECSP078014A (https=)
GT (1) GT200600263A (https=)
IL (1) IL187486A0 (https=)
MA (1) MA29722B1 (https=)
MX (1) MX2007015430A (https=)
NO (1) NO20080244L (https=)
TN (1) TNSN07474A1 (https=)
WO (1) WO2006138317A2 (https=)
ZA (1) ZA200710769B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5274261B2 (ja) 2006-12-07 2013-08-28 第一三共株式会社 低置換度ヒドロキシプロピルセルロースを含有する医薬組成物
EP2100607A4 (en) * 2006-12-07 2010-01-06 Daiichi Sankyo Co Ltd COATING COMPOSITION WITH IMPROVED DURABILITY
CN101686681B (zh) 2007-04-27 2015-04-01 锡德克斯药物公司 包含氯吡格雷和磺基烷基醚环糊精的制剂和其使用方法
WO2010132711A1 (en) 2009-05-13 2010-11-18 Cydex Pharmaceuticals, Inc. Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same
US10376532B2 (en) * 2009-11-11 2019-08-13 Chiesi Farmaceutici, S.P.A. Methods of treating, reducing the incidence of, and/or preventing ischemic events
EP2409685A3 (en) 2010-07-19 2012-02-01 Sanovel Ilac Sanayi ve Ticaret A.S. Orally-disintegrating formulations of prasugrel
TR201006802A1 (tr) * 2010-08-17 2012-03-21 Sanovel İlaç San. Ve Ti̇c. A.Ş. Prasugrelin oral yolla dağılan formülasyonları.
EP3106151A1 (en) 2015-06-19 2016-12-21 Sanovel Ilac Sanayi ve Ticaret A.S. Pharmaceutical compositions of prasugrel hydrobromide
WO2018167447A1 (en) * 2017-03-14 2018-09-20 University Of Sheffield Low dose aspirin (1-50 mg) together with antiplatelets such as ticagrelor of anticoagulants

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0641139A (ja) * 1991-09-09 1994-02-15 Sankyo Co Ltd ヒドロピリジン誘導体
US20020025957A1 (en) * 2000-06-09 2002-02-28 Stein Philip D. Lactam inhibitors of factor Xa and method
JP2002145883A (ja) * 2000-07-06 2002-05-22 Sankyo Co Ltd ヒドロピリジン誘導体酸付加塩
JP2002255814A (ja) * 2000-12-25 2002-09-11 Sankyo Co Ltd アスピリンを含有する医薬組成物
US6509348B1 (en) * 1998-11-03 2003-01-21 Bristol-Myers Squibb Company Combination of an ADP-receptor blocking antiplatelet drug and a thromboxane A2 receptor antagonist and a method for inhibiting thrombus formation employing such combination
WO2004098713A2 (en) * 2003-05-05 2004-11-18 Eli Lilly And Company Treating cardiovascular diseases with a compound of formula (i) (cs 747 - prasugrel; rn 150322-43-4)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE398624T1 (de) * 2000-07-06 2008-07-15 Daiichi Sankyo Co Ltd Säure-additionssalze von hydropyridinderivaten
NZ526540A (en) * 2000-12-25 2004-11-26 Sankyo Co Medicinal compositions containing aspirin and 2-acetoxy-5-(alpha-cyclopropylcarbonyl-2-flurobenzyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine useful in preventing thrombus or embolus diseases

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0641139A (ja) * 1991-09-09 1994-02-15 Sankyo Co Ltd ヒドロピリジン誘導体
US6509348B1 (en) * 1998-11-03 2003-01-21 Bristol-Myers Squibb Company Combination of an ADP-receptor blocking antiplatelet drug and a thromboxane A2 receptor antagonist and a method for inhibiting thrombus formation employing such combination
US20020025957A1 (en) * 2000-06-09 2002-02-28 Stein Philip D. Lactam inhibitors of factor Xa and method
JP2002145883A (ja) * 2000-07-06 2002-05-22 Sankyo Co Ltd ヒドロピリジン誘導体酸付加塩
JP2002255814A (ja) * 2000-12-25 2002-09-11 Sankyo Co Ltd アスピリンを含有する医薬組成物
WO2004098713A2 (en) * 2003-05-05 2004-11-18 Eli Lilly And Company Treating cardiovascular diseases with a compound of formula (i) (cs 747 - prasugrel; rn 150322-43-4)

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN6008019294; ＳＵＧＩＤＡＣＨＩ，　Ａ．　ＥＴ　ＡＬ．: '"Ｔｈｅ　ｉｎ　ｖｉｖｏ　ｐｈａｒｍａｃｏｌｏｇｉｃａｌ　ｐｒｏｆｉｌｅ　ｏｆ　ＣＳ-７４７，　ａ　ｎｏｖｅｌ　ａｎｔｉｐｌａｔｅｌｅｔ　ａｇｅｎｔ　ｗｉｔｈ　ｐｌａｔｅｌｅｔ　ＡＤＰ　ｒｅｃｅｐｔｏ' ＢＲＩＴＩＳＨ　ＪＯＵＲＮＡＬ　ＯＦ　ＰＨＡＲＭＡＣＯＬＯＧＹ Ｖｏｌ．１２９，　Ｎｏ．７, 200004, ｐｐ．１４３９-１４４６ *
JPN6012024565; 「今日の治療指針２００４年版（Ｖｏｌｕｍｅ　４６）」 , 20040101, ２４４-２４５頁, 株式会社医学書院 *
JPN6012024566; 「今日の治療指針２００２年版〔ポケット版〕」 , 20020101, ２２８-２２９頁, 株式会社医学書院 *
JPN6012024567; ＷＩＶＩＯＴＴ，Ｓ．，ＥＴ　ＡＬ．: '"Ｒａｎｄｏｍｉｚｅｄ　ｃｏｍｐａｒｉｓｏｎ　ｏｆ　ｐｒａｓｕｇｒｅｌ　（ＣＳ-７４７，　ＬＹ６４０３１５），　ａ　ｎｏｖｅｌ　ｔｈｉｅｎｏｐｙｒｉｄｉｎｅ　Ｐ２Ｙ１２　ａｎｔａｇｏｎｉｓｔ，　ｗｉｔ' ＣＩＲＣＵＬＡＴＩＯＮ ＶＯＬ．１１１，ＮＯ．２５, 20050628, ＰＰ．３３６６-３３７３ *

Also Published As

Publication number Publication date
AU2006259538A1 (en) 2006-12-28
IL187486A0 (en) 2008-06-05
US20090156632A1 (en) 2009-06-18
CA2612315A1 (en) 2006-12-28
ZA200710769B (en) 2009-09-30
EP1893205A2 (en) 2008-03-05
CN101198329A (zh) 2008-06-11
MA29722B1 (fr) 2008-09-01
TNSN07474A1 (en) 2009-03-17
KR20080016647A (ko) 2008-02-21
ECSP078014A (es) 2008-01-23
MX2007015430A (es) 2008-02-21
WO2006138317A2 (en) 2006-12-28
GT200600263A (es) 2007-02-23
EP1893205A4 (en) 2010-06-30
NO20080244L (no) 2008-01-14
WO2006138317A3 (en) 2007-05-03
BRPI0612624A2 (pt) 2016-11-29
EA200800075A1 (ru) 2008-04-28

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