JP2008543853A5 - - Google Patents

Info

Publication number

JP2008543853A5

JP2008543853A5 JP2008517022A JP2008517022A JP2008543853A5 JP 2008543853 A5 JP2008543853 A5 JP 2008543853A5 JP 2008517022 A JP2008517022 A JP 2008517022A JP 2008517022 A JP2008517022 A JP 2008517022A JP 2008543853 A5 JP2008543853 A5 JP 2008543853A5

Authority

JP

Japan

Prior art keywords

compound

formula

administration

daily

corresponds

Prior art date

2006-06-13

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 150000001875 compounds Chemical class 0.000 claims 14
• 238000000034 method Methods 0.000 claims 14
• 238000012423 maintenance Methods 0.000 claims 9
• JALHGCPDPSNJNY-UHFFFAOYSA-N [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4h-thieno[3,2-c]pyridin-2-yl] acetate;hydron;chloride Chemical compound Cl.C1CC=2SC(OC(=O)C)=CC=2CN1C(C=1C(=CC=CC=1)F)C(=O)C1CC1 JALHGCPDPSNJNY-UHFFFAOYSA-N 0.000 claims 5
• 229960004947 prasugrel hydrochloride Drugs 0.000 claims 5
• 239000003814 drug Substances 0.000 claims 4
• DTGLZDAWLRGWQN-UHFFFAOYSA-N prasugrel Chemical compound C1CC=2SC(OC(=O)C)=CC=2CN1C(C=1C(=CC=CC=1)F)C(=O)C1CC1 DTGLZDAWLRGWQN-UHFFFAOYSA-N 0.000 claims 4
• 150000003839 salts Chemical class 0.000 claims 4
• 238000004519 manufacturing process Methods 0.000 claims 3
• QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 claims 2
• 208000004476 Acute Coronary Syndrome Diseases 0.000 claims 2
• BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 claims 2
• 239000005465 B01AC22 - Prasugrel Substances 0.000 claims 2
• 208000005189 Embolism Diseases 0.000 claims 2
• VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 2
• 208000001435 Thromboembolism Diseases 0.000 claims 2
• 208000007536 Thrombosis Diseases 0.000 claims 2
• 229960001138 acetylsalicylic acid Drugs 0.000 claims 2
• 201000010099 disease Diseases 0.000 claims 2
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
• 229960004197 prasugrel Drugs 0.000 claims 2
• 230000002265 prevention Effects 0.000 claims 2
• 208000019553 vascular disease Diseases 0.000 claims 2
• 238000013146 percutaneous coronary intervention Methods 0.000 claims 1