JP2008539215A5 - - Google Patents
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- Publication number
- JP2008539215A5 JP2008539215A5 JP2008508290A JP2008508290A JP2008539215A5 JP 2008539215 A5 JP2008539215 A5 JP 2008539215A5 JP 2008508290 A JP2008508290 A JP 2008508290A JP 2008508290 A JP2008508290 A JP 2008508290A JP 2008539215 A5 JP2008539215 A5 JP 2008539215A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- aryl
- heteroaryl
- optionally substituted
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0508471.0A GB0508471D0 (en) | 2005-04-26 | 2005-04-26 | Therapeutic agents |
| GB0508471.0 | 2005-04-26 | ||
| PCT/GB2006/001505 WO2006114606A1 (en) | 2005-04-26 | 2006-04-25 | Fused thiazole derivatives as kinase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008539215A JP2008539215A (ja) | 2008-11-13 |
| JP2008539215A5 true JP2008539215A5 (https=) | 2012-08-30 |
| JP5243953B2 JP5243953B2 (ja) | 2013-07-24 |
Family
ID=34640185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008508290A Expired - Fee Related JP5243953B2 (ja) | 2005-04-26 | 2006-04-25 | キナーゼ阻害剤としての縮合チアゾール誘導体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7888344B2 (https=) |
| EP (1) | EP1881827B1 (https=) |
| JP (1) | JP5243953B2 (https=) |
| AT (1) | ATE526021T1 (https=) |
| AU (1) | AU2006239018B2 (https=) |
| CA (1) | CA2607426C (https=) |
| ES (1) | ES2373680T3 (https=) |
| GB (1) | GB0508471D0 (https=) |
| WO (1) | WO2006114606A1 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2365258T3 (es) * | 2006-06-26 | 2011-09-27 | Ucb Pharma S.A. | Derivados de tiazol condensados como inhibidores de quinasa. |
| GB0620059D0 (en) | 2006-10-10 | 2006-11-22 | Ucb Sa | Therapeutic agents |
| GB0620818D0 (en) | 2006-10-19 | 2006-11-29 | Ucb Sa | Therapeutic agents |
| ES2372320T3 (es) | 2006-11-15 | 2012-01-18 | Vertex Pharmceuticals Incorporated | Compuestos útiles como inhibidores de proteínas quinasas. |
| US9370508B2 (en) | 2007-02-20 | 2016-06-21 | Novartis Ag | Imidazoquinolines as dual lipid kinase and mTOR inhibitors |
| US7893060B2 (en) | 2007-06-12 | 2011-02-22 | F. Hoffmann-La Roche Ag | Thiazolopyrimidines and their use as inhibitors of phosphatidylinositol-3 kinase |
| NZ581919A (en) * | 2007-06-26 | 2011-08-26 | Ucb Pharma Sa | Fused thiazole derivatives as kinase inhibitors |
| WO2009036768A2 (en) * | 2007-09-19 | 2009-03-26 | H. Lundbeck A/S | Diagnosing potential weight gain in a subject |
| WO2009042607A1 (en) | 2007-09-24 | 2009-04-02 | Genentech, Inc. | Thiazolopyrimidine p13k inhibitor compounds and methods of use |
| US8354528B2 (en) | 2007-10-25 | 2013-01-15 | Genentech, Inc. | Process for making thienopyrimidine compounds |
| WO2009071890A1 (en) * | 2007-12-04 | 2009-06-11 | Ucb Pharma S.A. | Tricyclic kinase inhibitors |
| GB0723747D0 (en) * | 2007-12-04 | 2008-12-31 | Ucb Pharma Sa | Therapeutic agents |
| WO2009071895A1 (en) * | 2007-12-04 | 2009-06-11 | Ucb Pharma S.A. | Fused thiazole and thiophene derivatives as kinase inhibitors |
| JP5581219B2 (ja) | 2008-01-25 | 2014-08-27 | ミレニアム ファーマシューティカルズ， インコーポレイテッド | チオフェンおよびホスファチジルイノシトール３−キナーゼ（ｐｉ３ｋ）阻害薬としてのその使用 |
| WO2009120826A1 (en) * | 2008-03-27 | 2009-10-01 | Wyeth | 2-aryl- and 2-heteroarylthiazolyl compounds, methods for their preparation and use thereof |
| GB0805818D0 (en) * | 2008-03-31 | 2008-04-30 | Ucb Pharma Sa | Therapeutic agents |
| US8796314B2 (en) | 2009-01-30 | 2014-08-05 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| WO2010090716A1 (en) | 2009-01-30 | 2010-08-12 | Millennium Pharmaceuticals, Inc. | Heteroaryls and their use as pi3k inhibitors |
| US9090601B2 (en) | 2009-01-30 | 2015-07-28 | Millennium Pharmaceuticals, Inc. | Thiazole derivatives |
| US8410095B2 (en) | 2009-05-20 | 2013-04-02 | Glaxosmithkline Llc | Thiazolopyrimidinone derivatives as PI3 kinase inhibitors |
| CN102459272B (zh) | 2009-05-27 | 2014-08-06 | 健泰科生物技术公司 | 对P110δ具有选择性的为PI3K抑制剂的二环嘧啶化合物和使用方法 |
| CA2772371A1 (en) | 2009-05-27 | 2010-12-02 | F. Hoffmann-La Roche Ag | Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use |
| US8859768B2 (en) | 2010-08-11 | 2014-10-14 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| WO2012021611A1 (en) | 2010-08-11 | 2012-02-16 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| MX2013001660A (es) | 2010-08-11 | 2013-06-03 | Millenium Pharmaceuticals Inc | Heteroarilos y usos de los mismos. |
| TW201307309A (zh) | 2010-10-13 | 2013-02-16 | Millennium Pharm Inc | 雜芳基化合物及其用途 |
| US9382216B2 (en) | 2011-03-10 | 2016-07-05 | Lupin Limited | Substituted morpholines as modulators for the calcium sensing receptor |
| PH12019502378A1 (en) | 2013-05-01 | 2022-05-11 | Hoffmann La Roche | Biheteroaryl compounds and uses thereof |
| US10722484B2 (en) | 2016-03-09 | 2020-07-28 | K-Gen, Inc. | Methods of cancer treatment |
| CN107556199A (zh) * | 2017-09-24 | 2018-01-09 | 杨子辉 | 一种3,4‑二氯‑2‑氨基‑5‑氟联苯的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003521543A (ja) * | 2000-02-07 | 2003-07-15 | アボット ゲーエムベーハー ウント カンパニー カーゲー | ２−ベンゾチアゾリル尿素誘導体およびそのプロテインキナーゼ阻害剤としての使用 |
| CN1186324C (zh) * | 2000-04-27 | 2005-01-26 | 山之内制药株式会社 | 稠合杂芳基衍生物 |
| US7176214B2 (en) * | 2003-05-21 | 2007-02-13 | Bristol-Myers Squibb Company | Imidazo-fused oxazolo[4,5-β]pyridine and imidazo-fused thiazolo[4,5-β]pyridine based tricyclic compounds and pharmaceutical compositions comprising same |
-
2005
- 2005-04-26 GB GBGB0508471.0A patent/GB0508471D0/en not_active Ceased
-
2006
- 2006-04-25 CA CA2607426A patent/CA2607426C/en not_active Expired - Lifetime
- 2006-04-25 ES ES06726894T patent/ES2373680T3/es not_active Expired - Lifetime
- 2006-04-25 EP EP06726894A patent/EP1881827B1/en not_active Expired - Lifetime
- 2006-04-25 WO PCT/GB2006/001505 patent/WO2006114606A1/en not_active Ceased
- 2006-04-25 US US11/912,801 patent/US7888344B2/en active Active
- 2006-04-25 JP JP2008508290A patent/JP5243953B2/ja not_active Expired - Fee Related
- 2006-04-25 AT AT06726894T patent/ATE526021T1/de not_active IP Right Cessation
- 2006-04-25 AU AU2006239018A patent/AU2006239018B2/en not_active Ceased
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