JP2008538515A - マイクロ構造表面上における制御可能なナノ構造化 - Google Patents

マイクロ構造表面上における制御可能なナノ構造化 Download PDF

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Publication number
JP2008538515A
JP2008538515A JP2008503099A JP2008503099A JP2008538515A JP 2008538515 A JP2008538515 A JP 2008538515A JP 2008503099 A JP2008503099 A JP 2008503099A JP 2008503099 A JP2008503099 A JP 2008503099A JP 2008538515 A JP2008538515 A JP 2008538515A
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JP
Japan
Prior art keywords
combinations
group
substrate
product
titanium
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Pending
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JP2008503099A
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English (en)
Japanese (ja)
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JP2008538515A5 (enExample
Inventor
隆広 小川
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University of California
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University of California
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Publication of JP2008538515A publication Critical patent/JP2008538515A/ja
Publication of JP2008538515A5 publication Critical patent/JP2008538515A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C23COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23CCOATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C14/00Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
    • C23C14/02Pretreatment of the material to be coated
    • C23C14/021Cleaning or etching treatments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • CCHEMISTRY; METALLURGY
    • C23COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23CCOATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C14/00Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
    • C23C14/02Pretreatment of the material to be coated
    • C23C14/028Physical treatment to alter the texture of the substrate surface, e.g. grinding, polishing
    • CCHEMISTRY; METALLURGY
    • C23COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23CCOATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C14/00Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
    • C23C14/06Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the coating material
    • C23C14/14Metallic material, boron or silicon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0012Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
    • A61C8/0013Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30838Microstructures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/3084Nanostructures
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/24Structurally defined web or sheet [e.g., overall dimension, etc.]
    • Y10T428/24355Continuous and nonuniform or irregular surface on layer or component [e.g., roofing, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Metallurgy (AREA)
  • Organic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Physical Vapour Deposition (AREA)
JP2008503099A 2005-03-21 2006-03-21 マイクロ構造表面上における制御可能なナノ構造化 Pending JP2008538515A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66424305P 2005-03-21 2005-03-21
PCT/US2006/010281 WO2006102347A2 (en) 2005-03-21 2006-03-21 Controllable nanostructuring on micro-structured surfaces

Publications (2)

Publication Number Publication Date
JP2008538515A true JP2008538515A (ja) 2008-10-30
JP2008538515A5 JP2008538515A5 (enExample) 2009-05-07

Family

ID=37024537

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008503099A Pending JP2008538515A (ja) 2005-03-21 2006-03-21 マイクロ構造表面上における制御可能なナノ構造化

Country Status (6)

Country Link
US (1) US20110033661A1 (enExample)
EP (1) EP1874532A4 (enExample)
JP (1) JP2008538515A (enExample)
AU (1) AU2006227170A1 (enExample)
CA (1) CA2600718A1 (enExample)
WO (1) WO2006102347A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011502212A (ja) * 2008-09-22 2011-01-20 韓国科学技術院 金属単結晶ナノプレート及びその製造方法
KR101223977B1 (ko) 2010-05-26 2013-01-18 경상대학교산학협력단 독성을 억제하는 타이타늄 나노 구조 스텐트의 제작방법
JP2015501707A (ja) * 2011-12-16 2015-01-19 ヘルベルト ジェニッセン 構造物化された表面を有する基材及びその製造方法、及びその濡れ性の決定方法
WO2015125799A1 (ja) * 2014-02-21 2015-08-27 有限会社ITDN-Tokyo インプラント体

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120303127A1 (en) * 2005-05-06 2012-11-29 Titan Spine, Llc Implants having internal features for graft retention and load transfer between implant and vertebrae
US8758442B2 (en) * 2005-05-06 2014-06-24 Titan Spine, Llc Composite implants having integration surfaces composed of a regular repeating pattern
US8814939B2 (en) * 2005-05-06 2014-08-26 Titan Spine, Llc Implants having three distinct surfaces
AU2006315629B2 (en) 2005-11-14 2012-04-19 Biomet 3I, Llc Deposition of discrete nanoparticles on an implant surface
US8846551B2 (en) 2005-12-21 2014-09-30 University Of Virginia Patent Foundation Systems and methods of laser texturing of material surfaces and their applications
US8753990B2 (en) * 2005-12-21 2014-06-17 University Of Virginia Patent Foundation Systems and methods of laser texturing and crystallization of material surfaces
US20070259427A1 (en) * 2006-03-27 2007-11-08 Storey Daniel M Modified surfaces for attachment of biological materials
WO2008016712A2 (en) * 2006-08-02 2008-02-07 Inframat Corporation Medical devices and methods of making and using
US7972648B2 (en) 2006-10-24 2011-07-05 Biomet 3I, Llc Deposition of discrete nanoparticles on a nanostructured surface of an implant
US20100204777A1 (en) * 2007-05-03 2010-08-12 Chameleon Scientific Corporation Inhibitory cell adhesion surfaces
US7914856B2 (en) 2007-06-29 2011-03-29 General Electric Company Method of preparing wetting-resistant surfaces and articles incorporating the same
EP2022447A1 (en) 2007-07-09 2009-02-11 Astra Tech AB Nanosurface
JP5806466B2 (ja) 2008-01-28 2015-11-10 バイオメット・3アイ・エルエルシー 親水性を向上させたインプラント表面
US8641418B2 (en) 2010-03-29 2014-02-04 Biomet 3I, Llc Titanium nano-scale etching on an implant surface
US10131086B2 (en) 2011-06-30 2018-11-20 University Of Virginia Patent Foundation Micro-structure and nano-structure replication methods and article of manufacture
US8992619B2 (en) * 2011-11-01 2015-03-31 Titan Spine, Llc Microstructured implant surfaces
WO2013142480A1 (en) * 2012-03-20 2013-09-26 Titan Spine, Llc Friction-fit spinal endplate and endplate-preserving method
ES2671740T3 (es) 2012-03-20 2018-06-08 Biomet 3I, Llc Superficie de tratamiento para una superficie de implante
DE102012213787A1 (de) * 2012-08-03 2014-02-06 Robert Bosch Gmbh Oberflächenstrukturierung für zellbiologische und/oder medizinische Anwendungen
US20140277483A1 (en) * 2013-03-14 2014-09-18 Titan Spine, Llc Surface and subsurface chemistry of an integration surface
US20160120625A1 (en) * 2013-06-07 2016-05-05 Straumann Holding Ag Abutment
CN103668390B (zh) * 2014-01-02 2016-10-26 四川大学 具有微米-纳米粗糙结构表面的钛或钛合金材料及制备方法
US10687956B2 (en) 2014-06-17 2020-06-23 Titan Spine, Inc. Corpectomy implants with roughened bioactive lateral surfaces
US20160168688A1 (en) * 2014-12-15 2016-06-16 Cheng-Shang Tsao Method for preparation of composite composition
ES2882580T3 (es) * 2015-08-03 2021-12-02 Zanini Auto Grup Sa Componente de prótesis y procedimiento para su fabricación
TWI726940B (zh) 2015-11-20 2021-05-11 美商泰坦脊柱股份有限公司 積層製造整形外科植入物之方法
WO2017087027A1 (en) 2015-11-22 2017-05-26 Tyber Medical Llc Anti-microbial and osteointegation nanotextured surfaces
JP2019527591A (ja) 2016-08-03 2019-10-03 タイタン スパイン インコーポレイテッドTitan Spine,Inc. 骨誘導を増強するインプラント表面
RU2702670C2 (ru) * 2018-03-19 2019-10-09 федеральное государственное бюджетное образовательное учреждение высшего образования "Рязанский государственный университет имени С.А. Есенина" Способ упрочнения металлических поверхностей
WO2020020887A1 (en) 2018-07-24 2020-01-30 Straumann Holding Ag Dental article with a coating comprising nanostructures made of yttria-stabilized zirconia

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000102601A (ja) * 1998-09-28 2000-04-11 Natl Res Inst For Metals 骨適合性チタン材料
JP2003530972A (ja) * 2000-04-17 2003-10-21 ニュクリスト ファーマシューティカルズ コーポレーション 抗菌生体吸収性材料
JP2005503178A (ja) * 2000-01-25 2005-02-03 ボストン サイエンティフィック リミテッド 蒸着による医療器具の製造

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5726524A (en) * 1996-05-31 1998-03-10 Minnesota Mining And Manufacturing Company Field emission device having nanostructured emitters
US7396593B2 (en) * 2003-05-19 2008-07-08 Kimberly-Clark Worldwide, Inc. Single ply tissue products surface treated with a softening agent
DE10323597A1 (de) * 2003-05-19 2004-12-09 Aesculap Ag & Co. Kg Medizintechnisches Produkt, Verfahren zu seiner Herstellung und Verwendung
EP1502570A1 (de) * 2003-08-01 2005-02-02 Nanosolutions GmbH Röntgenopakes Dentalmaterial mit oberflächenmodifizierten Nanopartikeln

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000102601A (ja) * 1998-09-28 2000-04-11 Natl Res Inst For Metals 骨適合性チタン材料
JP2005503178A (ja) * 2000-01-25 2005-02-03 ボストン サイエンティフィック リミテッド 蒸着による医療器具の製造
JP2003530972A (ja) * 2000-04-17 2003-10-21 ニュクリスト ファーマシューティカルズ コーポレーション 抗菌生体吸収性材料

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6012014560; バイオエンジニアリング講演会講演論文集 Vol.17th, 200501, p295-296 *
JPN6012014561; Journal of Biomedical Materials Research. Part A. Vol.72,No.3, 20050301, p296-305 *
JPN6012014562; Process Mineralogy XIII , 1995, p181-187 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011502212A (ja) * 2008-09-22 2011-01-20 韓国科学技術院 金属単結晶ナノプレート及びその製造方法
KR101223977B1 (ko) 2010-05-26 2013-01-18 경상대학교산학협력단 독성을 억제하는 타이타늄 나노 구조 스텐트의 제작방법
JP2015501707A (ja) * 2011-12-16 2015-01-19 ヘルベルト ジェニッセン 構造物化された表面を有する基材及びその製造方法、及びその濡れ性の決定方法
WO2015125799A1 (ja) * 2014-02-21 2015-08-27 有限会社ITDN-Tokyo インプラント体
US10251730B2 (en) 2014-02-21 2019-04-09 Implant And Tissue Engineering Dental Network-Tokyo, Limited Co Implant body

Also Published As

Publication number Publication date
WO2006102347A3 (en) 2007-03-15
EP1874532A2 (en) 2008-01-09
WO2006102347A2 (en) 2006-09-28
US20110033661A1 (en) 2011-02-10
AU2006227170A1 (en) 2006-09-28
EP1874532A4 (en) 2008-08-06
CA2600718A1 (en) 2006-09-28

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