JP2008538508A5 - - Google Patents

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Publication number
JP2008538508A5
JP2008538508A5 JP2008507984A JP2008507984A JP2008538508A5 JP 2008538508 A5 JP2008538508 A5 JP 2008538508A5 JP 2008507984 A JP2008507984 A JP 2008507984A JP 2008507984 A JP2008507984 A JP 2008507984A JP 2008538508 A5 JP2008538508 A5 JP 2008538508A5
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JP
Japan
Prior art keywords
seq
antibody
ccx
ckr2
test agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008507984A
Other languages
English (en)
Japanese (ja)
Other versions
JP4963701B2 (ja
JP2008538508A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2006/015492 external-priority patent/WO2006116319A2/en
Publication of JP2008538508A publication Critical patent/JP2008538508A/ja
Publication of JP2008538508A5 publication Critical patent/JP2008538508A5/ja
Application granted granted Critical
Publication of JP4963701B2 publication Critical patent/JP4963701B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2008507984A 2005-04-21 2006-04-19 Ｃｃｘ−ｃｋｒ２を結合する試薬 Active JP4963701B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67414005P 2005-04-21 2005-04-21
US60/674,140 2005-04-21
PCT/US2006/015492 WO2006116319A2 (en) 2005-04-21 2006-04-19 Reagents that bind ccx-ckr2

Publications (3)

Publication Number Publication Date
JP2008538508A JP2008538508A (ja) 2008-10-30
JP2008538508A5 true JP2008538508A5 (enExample) 2009-05-21
JP4963701B2 JP4963701B2 (ja) 2012-06-27

Family

ID=37215373

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008507984A Active JP4963701B2 (ja) 2005-04-21 2006-04-19 Ｃｃｘ−ｃｋｒ２を結合する試薬

Country Status (14)

Country Link
US (2) US7678891B2 (enExample)
EP (1) EP1871804B1 (enExample)
JP (1) JP4963701B2 (enExample)
KR (1) KR101289567B1 (enExample)
CN (1) CN101163718B (enExample)
AU (1) AU2006238855B2 (enExample)
CA (1) CA2606222C (enExample)
DK (1) DK1871804T3 (enExample)
ES (1) ES2434852T3 (enExample)
IL (1) IL186509A (enExample)
MX (1) MX2007013108A (enExample)
PL (1) PL1871804T3 (enExample)
PT (1) PT1871804E (enExample)
WO (1) WO2006116319A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8088895B2 (en) * 2006-10-18 2012-01-03 Chemocentryx, Inc. Antibodies that bind CXCR7 epitopes
US9512236B2 (en) 2006-12-19 2016-12-06 Ablynx N.V. Amino acid sequences directed against GPCRS and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
WO2012130874A1 (en) 2011-03-28 2012-10-04 Ablynx Nv Bispecific anti-cxcr7 immunoglobulin single variable domains
JP6034023B2 (ja) 2008-05-16 2016-11-30 アブリンクス エン．ヴェー． Ｃｘｃｒ４及び他のｇｐｃｒに指向性を有するアミノ酸配列及びそれを含む化合物
EP2399934B1 (en) * 2009-02-20 2017-09-06 The University of Tokyo Novel monoclonal antibody, and use thereof
WO2011117423A1 (en) 2010-03-26 2011-09-29 Ablynx N.V. Immunoglobulin single variable domains directed against cxcr7
US12448373B2 (en) 2021-04-19 2025-10-21 Amgen Inc. Azetidinyl-acetamides as CXCR7 inhibitors

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US4256108A (en) * 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) * 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US4927838A (en) * 1987-07-10 1990-05-22 Hoffman-La Roche Inc. Pyridine compounds which are useful in treating a disease state characterized by an excess of platelet activating factors
US6537764B1 (en) 1995-01-19 2003-03-25 Children's Medical Center Corporation Method of identifying inhibitors of C—C chemokine receptor 3
SE9600820D0 (sv) * 1996-03-01 1996-03-01 Pharmacia Ab Antibodies and their use
GB9712818D0 (en) * 1996-07-08 1997-08-20 Cambridge Antibody Tech Labelling and selection of specific binding molecules
DE69737656T2 (de) 1996-09-10 2008-01-03 Theodor Kocher Institut Cxcr3 chemokine rezeptor, antikoerper, nukleinsaeure und deren verfahren zur anwendung
US6140064A (en) * 1996-09-10 2000-10-31 Theodor-Kocher Institute Method of detecting or identifying ligands, inhibitors or promoters of CXC chemokine receptor 3
US5876946A (en) * 1997-06-03 1999-03-02 Pharmacopeia, Inc. High-throughput assay
EP0897980A3 (en) 1997-08-20 2002-04-17 Smithkline Beecham Corporation CXCR4B: A human splice variant of CXCR4 chemokine receptor
CA2242308A1 (en) * 1997-12-08 1999-06-08 Smithkline Beecham Laboratoires Pharmaceutiques Novel compounds
US6306653B1 (en) * 1998-01-20 2001-10-23 Codon Diagnostics, Llc Detection and treatment of breast disease
CA2320144A1 (en) 1998-02-10 1999-08-12 Millennium Pharmaceuticals, Inc. Neokine protein and nucleic acid molecules and uses therefor
NZ507161A (en) 1998-03-30 2003-12-19 Northwest Biotherapeutics Inc Theraupeutic and diagonistic applications based on the role of the CXCR-4 gene in tumorigenesis
US6287765B1 (en) * 1998-05-20 2001-09-11 Molecular Machines, Inc. Methods for detecting and identifying single molecules
US6329510B1 (en) * 1999-01-29 2001-12-11 Millennium Pharmaceuticals, Inc. Anti-CCR1 antibodies and methods of use therefor
US6329159B1 (en) * 1999-03-11 2001-12-11 Millennium Pharmaceuticals, Inc. Anti-GPR-9-6 antibodies and methods of identifying agents which modulate GPR-9-6 function
US6365356B1 (en) * 1999-03-17 2002-04-02 Cornell Research Foundation, Inc. Receptors that regulate cell signaling relating to chemokines
CA2367173A1 (en) * 1999-04-08 2000-10-12 The General Hospital Corporation Purposeful movement of human migratory cells away from an agent source
US20020061599A1 (en) * 1999-12-30 2002-05-23 Elling Christian E. Method of identifying ligands of biological target molecules
CA2399593A1 (en) * 2000-02-09 2001-08-16 Human Genome Sciences, Inc. Antibodies to ccr5
US20020064770A1 (en) * 2000-03-21 2002-05-30 Nestor John J. Binding compounds and methods for identifying binding compounds
AU2001271502A1 (en) * 2000-06-26 2002-01-08 Gpc Biotech Ag Methods and compositions for isolating biologically active antibodies
US7871619B2 (en) * 2001-11-30 2011-01-18 Chemocentryx, Inc. Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
US7253007B2 (en) * 2001-11-30 2007-08-07 Chemocentryx, Inc. Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
CA2511242C (en) * 2002-12-20 2010-01-12 Anita Melikian Inhibitors of human tumor-expressed ccxckr2
WO2004099781A2 (en) * 2003-05-05 2004-11-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein-coupled receptor rdc1 (rdc1)

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