JP2008538280A - 脂質二分子膜の製造方法 - Google Patents

脂質二分子膜の製造方法 Download PDF

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Publication number
JP2008538280A
JP2008538280A JP2008504448A JP2008504448A JP2008538280A JP 2008538280 A JP2008538280 A JP 2008538280A JP 2008504448 A JP2008504448 A JP 2008504448A JP 2008504448 A JP2008504448 A JP 2008504448A JP 2008538280 A JP2008538280 A JP 2008538280A
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lipid
planar
lipid bilayer
vesicles
peptide
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JP2008504448A
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English (en)
Japanese (ja)
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JP2008538280A5 (enExample
Inventor
チョー、ナムジュン
カーチス、フランク・ダブリュー
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Leland Stanford Junior University
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Leland Stanford Junior University
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31678—Of metal

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
JP2008504448A 2005-03-29 2006-03-29 脂質二分子膜の製造方法 Pending JP2008538280A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66664705P 2005-03-29 2005-03-29
PCT/US2006/012085 WO2006110350A2 (en) 2005-03-29 2006-03-29 Method of fabricating lipid bilayer membranes on solid supports

Publications (2)

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JP2008538280A true JP2008538280A (ja) 2008-10-23
JP2008538280A5 JP2008538280A5 (enExample) 2009-04-23

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JP2008504448A Pending JP2008538280A (ja) 2005-03-29 2006-03-29 脂質二分子膜の製造方法

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US (1) US8211712B2 (enExample)
JP (1) JP2008538280A (enExample)
WO (1) WO2006110350A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8728793B2 (en) 2007-07-19 2014-05-20 The Board Of Trustees Of The Leland Stanford Junior University Amphipathic alpha-helical peptide compositions as antiviral agents
GB0716264D0 (en) 2007-08-21 2007-09-26 Isis Innovation Bilayers
MX2010011680A (es) * 2008-04-25 2011-05-03 Univ Northwestern Nanoestructuras adecuadas para secuestrar colesterol y otras moleculas.
US20130034599A1 (en) 2010-01-19 2013-02-07 Northwestern University Synthetic nanostructures including nucleic acids and/or other entities
EP2444808A1 (en) 2010-10-21 2012-04-25 Fredrik Höök Method for fusion of lipid bilayers
WO2015013673A1 (en) 2013-07-25 2015-01-29 Aurasense Therapeutics, Llc Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
US10568898B2 (en) 2013-08-13 2020-02-25 Northwestern University Lipophilic nanoparticles for drug delivery
US10427124B2 (en) * 2013-09-19 2019-10-01 Nanyang Technological University Methods for controlling assembly of lipids on a solid support
EP2886663A1 (en) 2013-12-19 2015-06-24 Centre National de la Recherche Scientifique (CNRS) Nanopore sequencing using replicative polymerases and helicases
US10434064B2 (en) 2014-06-04 2019-10-08 Exicure, Inc. Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications
JP6741673B2 (ja) 2014-10-06 2020-08-19 イグジキュア, インコーポレーテッドExicure, Inc. 抗ｔｎｆ化合物
FR3027679B1 (fr) 2014-10-28 2016-12-09 Univ Claude Bernard Lyon Ensemble support / peptide / bicouche lipidique, procedes de preparation et procedes de detection associes
US10078092B2 (en) 2015-03-18 2018-09-18 Northwestern University Assays for measuring binding kinetics and binding capacity of acceptors for lipophilic or amphiphilic molecules
KR102617833B1 (ko) 2016-05-06 2023-12-27 엑시큐어 오퍼레이팅 컴퍼니 인터류킨 17 수용체 mRNA의 특이적 녹다운을 위한 안티센스 올리고뉴클레오티드 (ASO)를 제시하는 리포좀성 구형 핵산 (SNA) 구축물
KR102477244B1 (ko) * 2017-02-15 2022-12-15 난양 테크놀러지컬 유니버시티 고체-지지된 인지질 이중층의 제조방법
US11696954B2 (en) 2017-04-28 2023-07-11 Exicure Operating Company Synthesis of spherical nucleic acids using lipophilic moieties
WO2020041480A1 (en) 2018-08-21 2020-02-27 The Regents Of The University Of California High-throughput system and method for the temporary permeabilization of cells using lipid bilayers
CN113599861B (zh) * 2021-08-13 2023-06-27 广东石油化工学院 一种利用修饰基底分离磷脂膜中胆固醇的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09236571A (ja) * 1996-02-27 1997-09-09 Bayer Ag 固体支持膜バイオセンサー

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US5364851A (en) * 1991-06-14 1994-11-15 International Synthecon, Llc Conformationally restricted biologically active peptides, methods for their production and uses thereof
US6306598B1 (en) * 1992-11-13 2001-10-23 Regents Of The University Of California Nucleic acid-coupled colorimetric analyte detectors
US5502022A (en) * 1994-05-16 1996-03-26 Biosepra, Inc. Chromatography adsorbents utilizing mercapto heterocyclic ligands
US5521702A (en) * 1994-06-14 1996-05-28 Salamon; Zdzislaw Reusable biocompatible interface for immobilization of materials on a solid support
US5997861A (en) * 1994-10-31 1999-12-07 Burstein Laboratories, Inc. Antiviral supramolecules containing target-binding molecules and therapeutic molecules bound to spectrin
US6344436B1 (en) * 1996-01-08 2002-02-05 Baylor College Of Medicine Lipophilic peptides for macromolecule delivery
US5864814A (en) * 1996-12-04 1999-01-26 Justsystem Corp. Voice-generating method and apparatus using discrete voice data for velocity and/or pitch
ATE293135T1 (de) * 1998-12-22 2005-04-15 Ciba Sc Pfersee Gmbh Wässrige dispersionen für die textilveredlung
US6541071B1 (en) * 2000-03-23 2003-04-01 Corning Incorporated Method for fabricating supported bilayer-lipid membranes
US7326536B2 (en) * 2001-05-03 2008-02-05 Eli Lilly And Company Agents for treatment of HCV and methods of use
WO2005084369A2 (en) * 2004-03-03 2005-09-15 The Regents Of The University Of California Arrays of colloidal crystals
US20060068503A1 (en) * 2004-09-10 2006-03-30 John Cuppoletti Solid support membranes for ion channel arrays and sensors: application ro rapid screening of pharmacological compounds
JP4263154B2 (ja) * 2004-09-30 2009-05-13 日立ソフトウエアエンジニアリング株式会社 機能性微粒子アレイ及びその使用方法
SE0403139D0 (sv) * 2004-12-23 2004-12-23 Nanoxis Ab Device and use thereof
JP2007040974A (ja) * 2005-06-30 2007-02-15 Omron Corp 生体分子固定化基板、バイオチップ及びバイオセンサ
US20070224637A1 (en) * 2006-03-24 2007-09-27 Mcauliffe Joseph C Oxidative protection of lipid layer biosensors
KR20080012605A (ko) * 2006-08-04 2008-02-12 삼성에스디아이 주식회사 탄성 에너지 장벽을 이용한 생체막 소자

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09236571A (ja) * 1996-02-27 1997-09-09 Bayer Ag 固体支持膜バイオセンサー

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US8211712B2 (en) 2012-07-03
WO2006110350A2 (en) 2006-10-19
US20090263670A1 (en) 2009-10-22
WO2006110350A3 (en) 2007-03-15

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