JP2008538183A - B型インフルエンザ菌 - Google Patents

B型インフルエンザ菌 Download PDF

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Publication number
JP2008538183A
JP2008538183A JP2008504533A JP2008504533A JP2008538183A JP 2008538183 A JP2008538183 A JP 2008538183A JP 2008504533 A JP2008504533 A JP 2008504533A JP 2008504533 A JP2008504533 A JP 2008504533A JP 2008538183 A JP2008538183 A JP 2008538183A
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JP
Japan
Prior art keywords
polypeptide
present
nucleic acid
sequence
polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008504533A
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English (en)
Japanese (ja)
Other versions
JP2008538183A5 (OSRAM
Inventor
ベガ マシグナニ,
リノ ラプオーリ,
エルベ テッテリン,
Original Assignee
ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド
ジ インスティチュート フォー ゲノミック リサーチ
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Filing date
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Application filed by ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド, ジ インスティチュート フォー ゲノミック リサーチ filed Critical ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド
Publication of JP2008538183A publication Critical patent/JP2008538183A/ja
Publication of JP2008538183A5 publication Critical patent/JP2008538183A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1242Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Materials For Photolithography (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2008504533A 2005-03-30 2006-03-30 B型インフルエンザ菌 Pending JP2008538183A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66792105P 2005-03-30 2005-03-30
PCT/US2006/012606 WO2006110413A2 (en) 2005-03-30 2006-03-30 Haemophilus influenzae type b

Publications (2)

Publication Number Publication Date
JP2008538183A true JP2008538183A (ja) 2008-10-16
JP2008538183A5 JP2008538183A5 (OSRAM) 2009-05-14

Family

ID=37087506

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008504533A Pending JP2008538183A (ja) 2005-03-30 2006-03-30 B型インフルエンザ菌

Country Status (11)

Country Link
US (4) US20100034822A1 (OSRAM)
EP (1) EP1871888A4 (OSRAM)
JP (1) JP2008538183A (OSRAM)
CN (1) CN101687025A (OSRAM)
AU (1) AU2006235045A1 (OSRAM)
BR (1) BRPI0609460A2 (OSRAM)
CA (1) CA2602665A1 (OSRAM)
MX (1) MX2007012057A (OSRAM)
NZ (2) NZ591415A (OSRAM)
RU (1) RU2007139915A (OSRAM)
WO (1) WO2006110413A2 (OSRAM)

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US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
PL3243526T3 (pl) 2010-07-06 2020-05-18 Glaxosmithkline Biologicals S.A. Dostarczanie rna w celu wyzwolenia wielu szlaków immunologicznych
PL2591114T3 (pl) 2010-07-06 2017-08-31 Glaxosmithkline Biologicals Sa Immunizacja dużych ssaków małymi dawkami rna
ES2557382T3 (es) 2010-07-06 2016-01-25 Glaxosmithkline Biologicals Sa Liposomas con lípidos que tienen un valor de pKa ventajoso para el suministro de ARN
US9770463B2 (en) 2010-07-06 2017-09-26 Glaxosmithkline Biologicals Sa Delivery of RNA to different cell types
FI4005592T3 (fi) 2010-07-06 2023-01-13 Virionin kaltaisia kuljetuspartikkeleita itsereplikoituville rna-molekyyleille
EP3542789A3 (en) 2010-08-31 2020-01-01 GlaxoSmithKline Biologicals SA Lipids suitable for liposomal delivery of protein-coding rna
HUE061068T2 (hu) 2010-08-31 2023-05-28 Glaxosmithkline Biologicals Sa Pegilált liposzómák immunogént kódoló RNS szállítására
EP4098324A1 (en) 2010-10-11 2022-12-07 GlaxoSmithKline Biologicals S.A. Antigen delivery platforms
JP2014516028A (ja) * 2011-05-11 2014-07-07 リースベック ヘルスケア スウェーデン アクティエボラーグ ラミニン及びビトロネクチン結合特性を有するタンパク質f−新規インフルエンザ菌付着因子
CA2840989A1 (en) 2011-07-06 2013-01-10 Novartis Ag Immunogenic combination compositions and uses thereof
EP4115875A1 (en) 2011-07-06 2023-01-11 GlaxoSmithKline Biologicals S.A. Liposomes having useful n:p ratio for delivery of rna molecules
EP2750707B1 (en) 2011-08-31 2018-10-24 GlaxoSmithKline Biologicals SA Pegylated liposomes for delivery of immunogen-encoding rna
CA2882382A1 (en) 2012-09-18 2014-03-27 Novartis Ag Outer membrane vesicles
WO2014136086A1 (en) 2013-03-08 2014-09-12 Novartis Ag Lipids and lipid compositions for the delivery of active agents
AR090303A1 (es) * 2013-03-11 2014-11-05 Consejo Nac Invest Cient Tec Polipeptido mutado, cepa de bacterias que lo comprende y metodos para detectar diferentes cationes metalicos simultaneamente
RU2015155601A (ru) 2013-06-10 2017-07-14 Мерк Шарп И Доум Корп. Нейтрализующие цитомегаловирус (цмв) антигенсвязывающие белки
US10426737B2 (en) 2013-12-19 2019-10-01 Novartis Ag Lipids and lipid compositions for the delivery of active agents
EP3083556B1 (en) 2013-12-19 2019-12-25 Novartis AG Lipids and lipid compositions for the delivery of active agents
US10342761B2 (en) 2014-07-16 2019-07-09 Novartis Ag Method of encapsulating a nucleic acid in a lipid nanoparticle host
US10125092B2 (en) 2014-09-05 2018-11-13 Novartis Ag Lipids and lipid compositions for the delivery of active agents
EP3061826A1 (en) 2015-02-27 2016-08-31 Novartis AG Flavivirus replicons
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
GB201508860D0 (en) 2015-05-22 2015-07-01 Nat Univ Ireland Diagnostic method
US11401520B2 (en) 2016-10-21 2022-08-02 The Research Foundation For The State University Of New York Compositions and methods comprising permuted protein tags for facilitating overexpression, solubility, and purification of target proteins
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US20220143168A1 (en) * 2019-02-27 2022-05-12 Evaxion Biotech A/S Vaccines targeting H. influenzae
CN114126715A (zh) * 2019-05-31 2022-03-01 罗根生物技术有限公司 组合物以及解除细菌内毒素毒性的方法
US11357845B2 (en) * 2019-07-08 2022-06-14 The Trustees Of The University Of Pennsylvania Protein antigens for vaccinating against nontypeable Haemophilus influenzae
WO2022081750A1 (en) 2020-10-14 2022-04-21 George Mason Research Foundation, Inc. Ionizable lipids and methods of manufacture and use thereof
CA3191332A1 (en) * 2020-10-30 2022-05-05 Gen-Probe Incorporated Compositions and methods for detecting influenza a, influenza b, and sars-cov-2
WO2023021427A1 (en) 2021-08-16 2023-02-23 Glaxosmithkline Biologicals Sa Freeze-drying of lipid nanoparticles (lnps) encapsulating rna and formulations thereof
WO2023021421A1 (en) 2021-08-16 2023-02-23 Glaxosmithkline Biologicals Sa Low-dose lyophilized rna vaccines and methods for preparing and using the same
GB202303019D0 (en) 2023-03-01 2023-04-12 Glaxosmithkline Biologicals Sa Method of lyophilisation
GB202311382D0 (en) 2023-07-25 2023-09-06 Glaxosmithkline Biologicals Sa Lyophilised compostion

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JP2004516805A (ja) * 2000-03-21 2004-06-10 エリトラ ファーマシューティカルズ,インコーポレイテッド 原核生物における必須遺伝子の同定
WO2004113371A2 (en) * 2003-06-26 2004-12-29 Chiron Srl Virulence-associated adhesins

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Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
JP2004516805A (ja) * 2000-03-21 2004-06-10 エリトラ ファーマシューティカルズ,インコーポレイテッド 原核生物における必須遺伝子の同定
WO2004113371A2 (en) * 2003-06-26 2004-12-29 Chiron Srl Virulence-associated adhesins

Also Published As

Publication number Publication date
CN101687025A (zh) 2010-03-31
US20120093868A1 (en) 2012-04-19
EP1871888A4 (en) 2013-08-21
WO2006110413A2 (en) 2006-10-19
US20100034822A1 (en) 2010-02-11
NZ562381A (en) 2011-06-30
AU2006235045A1 (en) 2006-10-19
BRPI0609460A2 (pt) 2010-04-13
EP1871888A2 (en) 2008-01-02
CA2602665A1 (en) 2006-10-19
US20160024157A1 (en) 2016-01-28
RU2007139915A (ru) 2009-05-10
NZ591415A (en) 2012-10-26
MX2007012057A (es) 2007-11-23
US20140302078A1 (en) 2014-10-09
WO2006110413A9 (en) 2010-01-14

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