JP2008537673A5 - - Google Patents
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- Publication number
- JP2008537673A5 JP2008537673A5 JP2007553371A JP2007553371A JP2008537673A5 JP 2008537673 A5 JP2008537673 A5 JP 2008537673A5 JP 2007553371 A JP2007553371 A JP 2007553371A JP 2007553371 A JP2007553371 A JP 2007553371A JP 2008537673 A5 JP2008537673 A5 JP 2008537673A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- ephb2
- seq
- hvr
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64854105P | 2005-01-31 | 2005-01-31 | |
| US75684406P | 2006-01-05 | 2006-01-05 | |
| PCT/US2006/003502 WO2006083936A2 (en) | 2005-01-31 | 2006-01-31 | Anti-ephb2 antibodies and methods using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008537673A JP2008537673A (ja) | 2008-09-25 |
| JP2008537673A5 true JP2008537673A5 (https=) | 2009-02-26 |
Family
ID=36341431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007553371A Pending JP2008537673A (ja) | 2005-01-31 | 2006-01-31 | 抗ｅｐｈｂ２抗体とその使用方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7767205B2 (https=) |
| EP (1) | EP1844076A2 (https=) |
| JP (1) | JP2008537673A (https=) |
| AU (1) | AU2006210837B2 (https=) |
| CA (1) | CA2594636A1 (https=) |
| NZ (1) | NZ556317A (https=) |
| WO (1) | WO2006083936A2 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1545613T3 (da) | 2002-07-31 | 2011-11-14 | Seattle Genetics Inc | Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom |
| EP2478912B1 (en) | 2003-11-06 | 2016-08-31 | Seattle Genetics, Inc. | Auristatin conjugates with anti-HER2 or anti-CD22 antibodies and their use in therapy |
| US8288352B2 (en) | 2004-11-12 | 2012-10-16 | Seattle Genetics, Inc. | Auristatins having an aminobenzoic acid unit at the N terminus |
| CA2593325A1 (en) * | 2005-01-06 | 2006-07-13 | Genentech, Inc. | Cancer prognostic, diagnostic and treatment methods |
| WO2007008848A2 (en) | 2005-07-07 | 2007-01-18 | Seattle Genetics, Inc. | Monomethylvaline compounds having phenylalanine carboxy modifications at the c-terminus |
| ES2708763T3 (es) | 2005-07-07 | 2019-04-11 | Seattle Genetics Inc | Compuestos de monometilvalina que tienen modificaciones de la cadena lateral de fenilalanina en el extremo C |
| US7750116B1 (en) | 2006-02-18 | 2010-07-06 | Seattle Genetics, Inc. | Antibody drug conjugate metabolites |
| DK2061510T3 (en) * | 2006-08-31 | 2016-09-05 | A C N 135 493 391 Pty Ltd As Trustee For Conca Unit Trust | Treatment and / or prevention of Barrett's esophagus using anti-EphB4 antibody-containing compositions |
| PE20090943A1 (es) | 2007-07-16 | 2009-08-05 | Genentech Inc | Anticuerpos anti-cd79b e inmunoconjugados |
| EP2176295B1 (en) | 2007-07-16 | 2014-11-19 | Genentech, Inc. | Humanized anti-cd79b antibodies and immunoconjugates and methods of use |
| US20090309617A1 (en) * | 2007-08-24 | 2009-12-17 | Ye Fang | Biosensor antibody functional mapping |
| KR101607346B1 (ko) | 2008-01-31 | 2016-03-29 | 제넨테크, 인크. | 항-ｃｄ７９ｂ 항체 및 면역접합체 및 사용 방법 |
| EP2496942B1 (en) | 2009-11-07 | 2017-03-22 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN104640572B (zh) * | 2012-05-15 | 2018-04-27 | 索伦托医疗有限公司 | 药物偶联物，偶联方法，及其用途 |
| AU2014337317A1 (en) | 2013-10-15 | 2016-09-15 | Sorrento Therapeutics Inc. | Drug-conjugates with a targeting molecule and two different drugs |
| NZ758049A (en) | 2013-10-15 | 2024-03-22 | Seagen Inc | Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics |
| WO2015117711A1 (en) * | 2014-02-06 | 2015-08-13 | Arsanis Biosciences Gmbh | E. coli specific antibody sequences |
| HUE049175T2 (hu) | 2014-09-23 | 2020-09-28 | Hoffmann La Roche | Eljárás anti-CD79b immunkonjugátumok alkalmazására |
| EP3250238B1 (en) | 2015-01-28 | 2022-06-01 | Sorrento Therapeutics, Inc. | Antibody drug conjugates |
| WO2017089606A1 (en) * | 2015-11-26 | 2017-06-01 | Kotter Mark Reinhard | Therapy to increase remyelination |
| US11793880B2 (en) | 2015-12-04 | 2023-10-24 | Seagen Inc. | Conjugates of quaternized tubulysin compounds |
| KR20180090290A (ko) | 2015-12-04 | 2018-08-10 | 시애틀 지네틱스, 인크. | 사차화 튜불리신 화합물들의 컨쥬게이트들 |
| CN109843919A (zh) | 2016-03-25 | 2019-06-04 | 西雅图基因公司 | 用于制备聚乙二醇化的药物-接头及其中间体的方法 |
| EP3436480A4 (en) | 2016-03-30 | 2019-11-27 | Musc Foundation for Research Development | METHOD FOR THE TREATMENT AND DIAGNOSIS OF CANCER BY TARGETING GLYCOPROTEIN A REPETITION PREDOMINANT (GARP) AND FOR EFFECTIVE IMMUNOTHERAPY ALONE OR IN COMBINATION |
| KR102648564B1 (ko) | 2017-03-24 | 2024-03-19 | 씨젠 인크. | 글루쿠로니드 약물-링커의 제조 공정 및 그 중간물 |
| US20230312732A1 (en) * | 2020-06-17 | 2023-10-05 | 4C Biomed Services Ltd. | Ephb2 antibody and use thereof in combination therapy |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5622701A (en) * | 1994-06-14 | 1997-04-22 | Protein Design Labs, Inc. | Cross-reacting monoclonal antibodies specific for E- and P-selectin |
| IL156009A0 (en) * | 2000-11-20 | 2003-12-23 | California Inst Of Techn | Artery smooth muscle and vein smooth muscle specific proteins and uses therefor |
| PT2000545E (pt) * | 2001-06-20 | 2011-12-21 | Genentech Inc | Composições e métodos para o diagnóstico e tratamento do tumor pulmonar |
| AU2003244817B2 (en) * | 2002-06-28 | 2010-08-26 | Domantis Limited | Antigen-binding immunoglobulin single variable domains and dual-specific constructs |
| AU2003291736A1 (en) * | 2002-11-05 | 2004-06-03 | Cell Signaling Technology, Inc. | Methods and materials for examining pathways associated with glioblastoma progression |
| EP2478912B1 (en) * | 2003-11-06 | 2016-08-31 | Seattle Genetics, Inc. | Auristatin conjugates with anti-HER2 or anti-CD22 antibodies and their use in therapy |
| WO2005101017A1 (en) * | 2004-04-07 | 2005-10-27 | Genentech, Inc. | Mass spectrometry of antibody conjugates |
| CA2593325A1 (en) * | 2005-01-06 | 2006-07-13 | Genentech, Inc. | Cancer prognostic, diagnostic and treatment methods |
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2006
- 2006-01-31 JP JP2007553371A patent/JP2008537673A/ja active Pending
- 2006-01-31 AU AU2006210837A patent/AU2006210837B2/en not_active Ceased
- 2006-01-31 EP EP06720045A patent/EP1844076A2/en not_active Ceased
- 2006-01-31 WO PCT/US2006/003502 patent/WO2006083936A2/en not_active Ceased
- 2006-01-31 CA CA002594636A patent/CA2594636A1/en not_active Abandoned
- 2006-01-31 NZ NZ556317A patent/NZ556317A/en not_active IP Right Cessation
-
2007
- 2007-07-31 US US11/831,787 patent/US7767205B2/en not_active Expired - Fee Related
-
2010
- 2010-06-08 US US12/796,496 patent/US20100278842A1/en not_active Abandoned