JP2008536487A5 - - Google Patents
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- Publication number
- JP2008536487A5 JP2008536487A5 JP2008501411A JP2008501411A JP2008536487A5 JP 2008536487 A5 JP2008536487 A5 JP 2008536487A5 JP 2008501411 A JP2008501411 A JP 2008501411A JP 2008501411 A JP2008501411 A JP 2008501411A JP 2008536487 A5 JP2008536487 A5 JP 2008536487A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- activated
- tumor cell
- atcp
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000000822 natural killer cell Anatomy 0.000 claims 13
- 238000002360 preparation method Methods 0.000 claims 9
- 238000000034 method Methods 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 8
- 210000004881 tumor cell Anatomy 0.000 claims 8
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 201000011510 cancer Diseases 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 4
- 208000031261 Acute myeloid leukaemia Diseases 0.000 claims 2
- 208000010839 B-cell chronic lymphocytic leukemia Diseases 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 102100025137 Early activation antigen CD69 Human genes 0.000 claims 2
- 101000934374 Homo sapiens Early activation antigen CD69 Proteins 0.000 claims 2
- 206010025323 Lymphomas Diseases 0.000 claims 2
- 230000003213 activating effect Effects 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 230000000735 allogeneic effect Effects 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 230000009089 cytolysis Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 208000025113 myeloid leukemia Diseases 0.000 claims 1
- 230000003827 upregulation Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0505508A GB0505508D0 (en) | 2005-03-17 | 2005-03-17 | Method |
| GB0505508.2 | 2005-03-17 | ||
| GB0514288.0 | 2005-07-12 | ||
| GB0514288A GB0514288D0 (en) | 2005-07-12 | 2005-07-12 | Method |
| PCT/GB2006/000960 WO2006097743A2 (en) | 2005-03-17 | 2006-03-16 | Method for actvating natural killer cells by tumor cell preparation in vitro |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012224042A Division JP5906168B2 (ja) | 2005-03-17 | 2012-10-09 | 腫瘍細胞調製物によってｉｎｖｉｔｒｏでナチュラルキラー細胞を活性化させるための方法 |
| JP2014212302A Division JP2015012876A (ja) | 2005-03-17 | 2014-10-17 | 腫瘍細胞調製物によってｉｎｖｉｔｒｏでナチュラルキラー細胞を活性化させるための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008536487A JP2008536487A (ja) | 2008-09-11 |
| JP2008536487A5 true JP2008536487A5 (OSRAM) | 2009-03-12 |
| JP5663135B2 JP5663135B2 (ja) | 2015-02-04 |
Family
ID=36992099
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008501411A Expired - Fee Related JP5663135B2 (ja) | 2005-03-17 | 2006-03-16 | 腫瘍細胞調製物によってｉｎｖｉｔｒｏでナチュラルキラー細胞を活性化させるための方法 |
| JP2012224042A Active JP5906168B2 (ja) | 2005-03-17 | 2012-10-09 | 腫瘍細胞調製物によってｉｎｖｉｔｒｏでナチュラルキラー細胞を活性化させるための方法 |
| JP2014212302A Withdrawn JP2015012876A (ja) | 2005-03-17 | 2014-10-17 | 腫瘍細胞調製物によってｉｎｖｉｔｒｏでナチュラルキラー細胞を活性化させるための方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012224042A Active JP5906168B2 (ja) | 2005-03-17 | 2012-10-09 | 腫瘍細胞調製物によってｉｎｖｉｔｒｏでナチュラルキラー細胞を活性化させるための方法 |
| JP2014212302A Withdrawn JP2015012876A (ja) | 2005-03-17 | 2014-10-17 | 腫瘍細胞調製物によってｉｎｖｉｔｒｏでナチュラルキラー細胞を活性化させるための方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US8257970B2 (OSRAM) |
| EP (2) | EP2399594B1 (OSRAM) |
| JP (3) | JP5663135B2 (OSRAM) |
| AU (1) | AU2006224313B2 (OSRAM) |
| CA (1) | CA2601197C (OSRAM) |
| DK (1) | DK1863905T3 (OSRAM) |
| ES (1) | ES2566335T3 (OSRAM) |
| PL (1) | PL1863905T3 (OSRAM) |
| WO (1) | WO2006097743A2 (OSRAM) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102230288B1 (ko) | 2006-04-14 | 2021-03-22 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 혈관 콜로니 형성 세포 |
| TWI498561B (zh) * | 2008-05-29 | 2015-09-01 | Transgene Sa | 用於預測癌症病患在免疫療法後是否易產生治療性免疫反應之方法及相關用途 |
| CN102575230A (zh) * | 2009-07-10 | 2012-07-11 | 马克·洛戴尔 | 活化的nk细胞的经保存的组合物及其使用方法 |
| HRP20181515T1 (hr) | 2011-11-30 | 2018-11-16 | Astellas Institute For Regenerative Medicine | Mezenhimne stromalne stanice i upotreba povezana s njima |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| WO2013132256A1 (en) | 2012-03-07 | 2013-09-12 | Ucl Business Plc | Compositions and methods for treating viral-mediated infection and disease in immunocompromised individuals |
| CN104321425B (zh) * | 2012-05-07 | 2018-08-10 | 株式会社Nkmax | 用于诱导和扩增源自外周血单个核细胞的自然杀伤细胞的方法 |
| WO2013168978A1 (ko) * | 2012-05-07 | 2013-11-14 | 고려대학교 산학협력단 | 말초혈액단핵구 유래 자연 살해세포의 유도 및 증식 방법 |
| WO2014011407A2 (en) | 2012-07-12 | 2014-01-16 | Imstem Biotechnology, Inc. | Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof |
| CN114558032B (zh) | 2012-12-21 | 2025-07-29 | 安斯泰来再生医药协会 | 由多能干细胞制备血小板的方法及其组合物 |
| EP3189132B1 (en) * | 2014-09-04 | 2020-06-24 | Stemcell Technologies Inc. | Soluble antibody complexes for t cell or nk cell activation and expansion |
| US10758567B2 (en) | 2015-09-16 | 2020-09-01 | Immune Ventures LLC | In vivo priming of natural killer cells |
| WO2018170309A1 (en) * | 2017-03-15 | 2018-09-20 | Immune Ventures, Llc | In vivo priming of natural killer cells |
| ES2871100T3 (es) * | 2015-12-07 | 2021-10-28 | Immune Ventures LLC | Cebado in vivo de linfocitos citolíticos naturales |
| NZ766453A (en) | 2018-02-01 | 2022-02-25 | Nkmax Co Ltd | Method of producing natural killer cells and composition for treating cancer |
| KR20250160211A (ko) | 2018-08-30 | 2025-11-11 | 이뮤니티바이오, 인크. | 다중-사슬 키메라 폴리펩타이드 및 이의 용도 |
| JP7474769B2 (ja) * | 2018-08-30 | 2024-04-25 | エイチシーダブリュー バイオロジックス インコーポレイテッド | 一本鎖および多鎖キメラポリペプチドならびにその使用方法 |
| CN113365663B (zh) | 2018-08-30 | 2025-11-21 | 免疫生物公司 | 单链嵌合多肽和其用途 |
| JP6838750B2 (ja) * | 2019-01-21 | 2021-03-03 | 株式会社ガイアバイオメディシン | Ｎｋ細胞を含む細胞集団の製造方法 |
| US11738052B2 (en) | 2019-06-21 | 2023-08-29 | HCW Biologics, Inc. | Multi-chain chimeric polypeptides and uses thereof |
| WO2021163298A1 (en) | 2020-02-11 | 2021-08-19 | HCW Biologics, Inc. | Methods of activating regulatory t cells |
| CA3169231A1 (en) | 2020-02-11 | 2021-08-19 | HCW Biologics, Inc. | Methods of treating age-related and inflammatory diseases |
| KR20220140535A (ko) | 2020-02-11 | 2022-10-18 | 에이치씨더블유 바이올로직스, 인크. | 크로마토그래피 수지 및 이의 용도 |
| JP7734693B2 (ja) | 2020-04-29 | 2025-09-05 | イミュニティーバイオ インコーポレイテッド | 抗ｃｄ２６タンパク質及びそれらの使用法 |
| US12024545B2 (en) | 2020-06-01 | 2024-07-02 | HCW Biologics, Inc. | Methods of treating aging-related disorders |
| KR20250118299A (ko) * | 2024-01-29 | 2025-08-06 | 인하대학교 산학협력단 | 전기자극 시스템을 활용한 자연살해세포의 암세포 살상 능력 증진 방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2263205T3 (es) * | 1997-04-30 | 2006-12-01 | Hans Klingemann | Estirpes celulares citoliticas naturales y metodos de uso. |
| US6849452B1 (en) * | 1998-03-03 | 2005-02-01 | Institut Gustave Roussy | Methods for activating natural killer (NK) cells and means for carrying out said methods |
| DK1594542T3 (da) | 2003-02-20 | 2010-10-11 | Seattle Genetics Inc | Anti-CD70 antistof-lægemiddelkonjugater og deres anvendelse ved behandling af cancer |
| US7435596B2 (en) * | 2004-11-04 | 2008-10-14 | St. Jude Children's Research Hospital, Inc. | Modified cell line and method for expansion of NK cell |
-
2006
- 2006-03-16 AU AU2006224313A patent/AU2006224313B2/en not_active Ceased
- 2006-03-16 CA CA2601197A patent/CA2601197C/en not_active Expired - Fee Related
- 2006-03-16 JP JP2008501411A patent/JP5663135B2/ja not_active Expired - Fee Related
- 2006-03-16 WO PCT/GB2006/000960 patent/WO2006097743A2/en not_active Ceased
- 2006-03-16 EP EP11002652.3A patent/EP2399594B1/en active Active
- 2006-03-16 EP EP06726410.1A patent/EP1863905B1/en not_active Not-in-force
- 2006-03-16 ES ES06726410.1T patent/ES2566335T3/es active Active
- 2006-03-16 DK DK06726410.1T patent/DK1863905T3/en active
- 2006-03-16 PL PL06726410T patent/PL1863905T3/pl unknown
-
2007
- 2007-09-17 US US11/856,466 patent/US8257970B2/en not_active Expired - Fee Related
-
2012
- 2012-08-31 US US13/601,153 patent/US8637308B2/en not_active Expired - Fee Related
- 2012-10-09 JP JP2012224042A patent/JP5906168B2/ja active Active
-
2013
- 2013-11-21 US US14/086,768 patent/US9655925B2/en not_active Expired - Fee Related
-
2014
- 2014-10-17 JP JP2014212302A patent/JP2015012876A/ja not_active Withdrawn
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