JP2008531647A5 - - Google Patents

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Publication number
JP2008531647A5
JP2008531647A5 JP2007557486A JP2007557486A JP2008531647A5 JP 2008531647 A5 JP2008531647 A5 JP 2008531647A5 JP 2007557486 A JP2007557486 A JP 2007557486A JP 2007557486 A JP2007557486 A JP 2007557486A JP 2008531647 A5 JP2008531647 A5 JP 2008531647A5
Authority
JP
Japan
Prior art keywords
preparation
preparation according
oligodeoxyribonucleotide
formulation
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007557486A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008531647A (ja
Filing date
Publication date
Priority claimed from IT000336A external-priority patent/ITMI20050336A1/it
Application filed filed Critical
Priority claimed from PCT/EP2006/060306 external-priority patent/WO2006094917A2/en
Publication of JP2008531647A publication Critical patent/JP2008531647A/ja
Publication of JP2008531647A5 publication Critical patent/JP2008531647A5/ja
Pending legal-status Critical Current

Links

JP2007557486A 2005-03-03 2006-02-27 抗腫瘍作用を有する製剤 Pending JP2008531647A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT000336A ITMI20050336A1 (it) 2005-03-03 2005-03-03 Formulazione ad attivita' anti-tumorale
US73140405P 2005-10-28 2005-10-28
PCT/EP2006/060306 WO2006094917A2 (en) 2005-03-03 2006-02-27 Oligodeoxyribonucleotides of 4000-10000 dalton for treating tumors

Publications (2)

Publication Number Publication Date
JP2008531647A JP2008531647A (ja) 2008-08-14
JP2008531647A5 true JP2008531647A5 (https=) 2009-04-02

Family

ID=36572331

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007557485A Expired - Fee Related JP5714203B2 (ja) 2005-03-03 2006-02-27 血管新生依存性腫瘍を治療するためのデフィブロチドおよび/またはオリゴデオキシリボヌクレオチド
JP2007557486A Pending JP2008531647A (ja) 2005-03-03 2006-02-27 抗腫瘍作用を有する製剤

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2007557485A Expired - Fee Related JP5714203B2 (ja) 2005-03-03 2006-02-27 血管新生依存性腫瘍を治療するためのデフィブロチドおよび/またはオリゴデオキシリボヌクレオチド

Country Status (9)

Country Link
US (2) US20080194506A1 (https=)
EP (2) EP1855697A2 (https=)
JP (2) JP5714203B2 (https=)
KR (3) KR20070120953A (https=)
AU (2) AU2006222045B2 (https=)
CA (2) CA2598613A1 (https=)
IL (3) IL185182A0 (https=)
MX (2) MX2007010754A (https=)
WO (2) WO2006094917A2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20031714A1 (it) 2003-09-05 2005-03-06 Gentium Spa Formazioni ad azione antitumorale.
EP1982722A1 (en) * 2007-04-16 2008-10-22 Gentium S.p.A. Use of oligotide for the treatment of renal diseases
EP2103689A1 (en) 2008-03-19 2009-09-23 Gentium S.p.A. Synthetic phosphodiester oligonucleotides and therapeutical uses thereof
US8187897B2 (en) 2008-08-19 2012-05-29 International Business Machines Corporation Fabricating product chips and die with a feature pattern that contains information relating to the product chip
EP2637672B1 (en) 2010-11-12 2018-08-22 Gentium S.r.l. Defibrotide for use in prophylaxis and/or treatment of graft versus host disease (gvhd).
ES2660969T5 (es) 2012-06-22 2021-09-03 Gentium S R L Método basado en euglobulina para determinar la actividad biológica de defibrotida
EP3026122A1 (en) 2014-11-27 2016-06-01 Gentium S.p.A. Cellular-based method for determining the potency of defibrotide
TW201909904A (zh) 2017-08-03 2019-03-16 愛爾蘭商爵士製藥愛爾蘭有限責任公司 高濃度調配物
CN112236149A (zh) 2018-04-12 2021-01-15 贾兹制药公司 用于预防和治疗细胞因子释放综合征和与免疫耗竭相关的神经毒性的去纤苷
US20220023533A1 (en) 2018-12-07 2022-01-27 Jazz Phrmaceticals Ireland Limited Subcutaneous delivery of high concentration formulations
EP4110287A1 (en) 2020-02-28 2023-01-04 Jazz Pharmaceuticals Ireland Limited Delivery of low viscosity formulations
TW202308659A (zh) 2021-05-06 2023-03-01 愛爾蘭商爵士製藥愛爾蘭有限責任公司 用於急性呼吸窘迫症候群之治療及預防的去纖維蛋白多核苷酸

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899481A (en) * 1970-11-03 1975-08-12 Crinos Industria Farmaco Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs
IT1043823B (it) * 1970-11-03 1980-02-29 Prephar Procedimento per l estrazione di acidi nucleici da organi animali
DE2154279A1 (de) * 1970-11-03 1972-05-25 Crinos Industria Farmaco Medikamente für das fibrinolytische System
IT1170214B (it) * 1983-09-12 1987-06-03 Crinos Industria Farmaco Composizione farmaceutica per la cura delle arteriopatie periferiche
IT1206341B (it) * 1984-02-16 1989-04-14 Crinos Industria Farmaco Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.
US4694134A (en) * 1985-05-28 1987-09-15 Ajax Magnethermic Corporation Apparatus for overheating edges of skelp for the production of compression welded pipe
US5223609A (en) * 1986-04-17 1993-06-29 Crinos Industria Farmacobiologica S.P.A. Process for obtaining chemically defined and reproducible polydeoxyribonucleotides
IT1190313B (it) * 1986-04-17 1988-02-16 Crinos Industria Farmaco Procedimento per l'ottenimento di polidesossiribonucleotidi chimicamente definiti e riproducibili e prodotto farmacologicamente attivo risultante
US5977083A (en) * 1991-08-21 1999-11-02 Burcoglu; Arsinur Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
US6699985B2 (en) * 1991-08-21 2004-03-02 Arsinur Burcoglu Method of treating HIV infection and related secondary infections thereof
IT1252174B (it) * 1991-12-09 1995-06-05 Crinos Industria Farmaco Oligodesossimibonucleotidi ad attivita' antiischemica e procedimenti per il loro ottenimento
US5578716A (en) * 1993-12-01 1996-11-26 Mcgill University DNA methyltransferase antisense oligonucleotides
AU754242B2 (en) * 1997-04-28 2002-11-07 Arsinur Burcoglu Method of treating HIV infection and related secondary infections thereof
WO1998054313A2 (en) * 1997-05-30 1998-12-03 Mcgill University Dna methyltransferase genomic sequences and antisense oligonucleotides
DE19740384A1 (de) * 1997-09-08 1999-03-11 Max Delbrueck Centrum Antisense Oligodesoxynukleotide (ODN) gegen Proteinkinase C (PKC)-Isoformen, ihre Verwendung und pharmazeutische Zubereitungen dieser ODN
WO2003027313A2 (en) * 2001-09-24 2003-04-03 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services SUPPRESSORS OF CpG OLIGONUCLEOTIDES AND METHODS OF USE
ITMI20031714A1 (it) * 2003-09-05 2005-03-06 Gentium Spa Formazioni ad azione antitumorale.

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