JP2008530050A5 - - Google Patents
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- Publication number
- JP2008530050A5 JP2008530050A5 JP2007554541A JP2007554541A JP2008530050A5 JP 2008530050 A5 JP2008530050 A5 JP 2008530050A5 JP 2007554541 A JP2007554541 A JP 2007554541A JP 2007554541 A JP2007554541 A JP 2007554541A JP 2008530050 A5 JP2008530050 A5 JP 2008530050A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- group
- butanol
- composition according
- chlorophenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05100942.1 | 2005-02-10 | ||
| EP05100942A EP1690858B1 (en) | 2005-02-10 | 2005-02-10 | Monohydrochloride salt of 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine |
| PCT/EP2006/050703 WO2006084833A1 (en) | 2005-02-10 | 2006-02-06 | Monohydrochloride salt of 1- [3- [3- (4-chlorophenyl) propoxy] propyl] -piperidine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008530050A JP2008530050A (ja) | 2008-08-07 |
| JP2008530050A5 true JP2008530050A5 (https=) | 2009-04-02 |
| JP5072604B2 JP5072604B2 (ja) | 2012-11-14 |
Family
ID=34938687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007554541A Expired - Lifetime JP5072604B2 (ja) | 2005-02-10 | 2006-02-06 | １−［３−［３−（４−クロロフェニル）プロポキシ］プロピル］−ピペリジン一塩酸塩 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US8207197B2 (https=) |
| EP (2) | EP1690858B1 (https=) |
| JP (1) | JP5072604B2 (https=) |
| KR (1) | KR101344271B1 (https=) |
| CN (1) | CN101155793B (https=) |
| AR (1) | AR054734A1 (https=) |
| AT (2) | ATE391716T1 (https=) |
| CA (1) | CA2597016C (https=) |
| CY (1) | CY1108428T1 (https=) |
| DE (2) | DE602005005941D1 (https=) |
| DK (1) | DK1846384T3 (https=) |
| ES (1) | ES2309948T3 (https=) |
| HR (1) | HRP20080446T3 (https=) |
| ME (1) | ME01103B (https=) |
| MX (1) | MX2007009574A (https=) |
| PL (1) | PL1846384T3 (https=) |
| PT (1) | PT1846384E (https=) |
| RS (1) | RS50624B (https=) |
| SI (1) | SI1846384T1 (https=) |
| TW (1) | TWI393711B (https=) |
| UY (1) | UY29369A1 (https=) |
| WO (1) | WO2006084833A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2167096A4 (en) * | 2007-06-13 | 2010-07-14 | Cypress Bioscience Inc | IMPROVING TOLERANCE TO MIRTAZAPINE AND A SECOND ACTIVE INGREDIENT BY THE COMBINED USE OF THEM |
| BRPI1008020A2 (pt) | 2009-02-11 | 2016-03-15 | Sunovion Pharmaceuticals Inc | antagonistas e agonistas inversos h3 da histamina e métodos de uso dos mesmos |
| SG176735A1 (en) | 2009-06-10 | 2012-01-30 | Sunovion Pharmaceuticals Inc | Histamine h3 inverse agonists and antagonists and methods of use thereof |
| MX2012002898A (es) | 2009-09-11 | 2012-04-02 | Sunovion Pharmaceuticals Inc | Agonistas y antagonistas inversos de histamina h3 y metodos de uso para los mismos. |
| WO2014199935A1 (ja) * | 2013-06-10 | 2014-12-18 | 株式会社エム・エス・エス | 小胞体ストレスシグナルを抑制することによる，薬剤の副作用としての体重増加や肥満を防止するために用いられる肥満防止剤 |
| CN103435575A (zh) * | 2013-08-06 | 2013-12-11 | 中国人民解放军军事医学科学院毒物药物研究所 | 1-（ 3-（ 3-（ 4-氯苯基）丙氧基）丙基）哌啶盐酸盐的制备方法 |
| CN104447620B (zh) * | 2014-11-28 | 2016-05-04 | 瑞阳制药有限公司 | 1-[3-[3-(4-氯苯基)丙氧基]丙基]-哌啶盐酸盐的制备方法 |
| EP3239138A1 (en) | 2016-04-25 | 2017-11-01 | Sandoz Ag | Hydrogen fumarate salt of 1-[3-[3-(4-chlorophenyl)propoxy]propyl]piperidine |
| WO2020092604A1 (en) * | 2018-10-30 | 2020-05-07 | Concert Pharmaceuticals, Inc. | Deuterated pitolisant |
| IT201900013941A1 (it) | 2019-08-05 | 2021-02-05 | Procos Spa | PROCESSO PER LA SINTESI DI PITOLISANT HCl |
| CN110804026B (zh) * | 2019-11-18 | 2022-04-01 | 苏州永健生物医药有限公司 | 1- (3- (3-（4-氯苯基）丙氧基)丙基)哌啶盐酸盐的合成方法 |
| US11945788B2 (en) | 2021-06-07 | 2024-04-02 | Nuray Chemicals Private Limited | Process for preparing pitolisant hydrochloride and solid-state forms thereof |
| US11623920B2 (en) | 2021-06-07 | 2023-04-11 | Nuray Chemicals Private Limited | Process for preparing pitolisant hydrochloride and solid-state forms thereof |
| EP4457219A4 (en) * | 2021-12-29 | 2025-12-10 | Biophore India Pharmaceuticals Pvt Ltd | SOLID FORMS OF 1-3-[3-(4-CHLOROPHENYL)PROPOXY]PROPYL PIPERIDINE HYDROCHLORIDE AND THEIR PREPARATION PROCESS |
| US20250281475A1 (en) * | 2022-05-04 | 2025-09-11 | Msn Laboratories Private Limited, R & D Center | A pharmaceutical composition of pitolisant hydrochloride and their process for the preparation |
| WO2024084379A1 (en) * | 2022-10-17 | 2024-04-25 | Biophore India Pharmaceuticals Pvt. Ltd | A NOVEL PROCESS FOR THE PREPARATION OF AMORPHOUS SOLID DISPERSION OF 1-{3-[3-(4-CHLOROPHENYL) PROPOXY] PROPYL} PIPERIDINE, HYDROCHLORIDE WITH HYDROXYPROPYL BETA-CYCLODEXTRIN (HPβCD) |
| EP4374854A1 (en) * | 2022-11-28 | 2024-05-29 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Pharmaceutical mixture comprising amorphous pitolisant |
| EP4688166A1 (en) | 2023-03-31 | 2026-02-11 | BIOPROJET Pharma | Polymorph form of pitolisant hydrochloride |
| WO2025082974A1 (en) | 2023-10-16 | 2025-04-24 | Bioprojet Pharma | New formulations of pitolisant and methods of use |
| EP4681704A1 (en) | 2024-07-18 | 2026-01-21 | BIOPROJET Pharma | New formulations of pitolisant |
| EP4732903A1 (en) * | 2024-10-28 | 2026-04-29 | BIOPROJET Pharma | Co-crystals of pitolisant hydrochloride |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0982300A3 (en) * | 1998-07-29 | 2000-03-08 | Societe Civile Bioprojet | Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications |
-
2005
- 2005-02-10 DE DE602005005941T patent/DE602005005941D1/de not_active Expired - Lifetime
- 2005-02-10 EP EP05100942A patent/EP1690858B1/en not_active Expired - Lifetime
- 2005-02-10 AT AT05100942T patent/ATE391716T1/de not_active IP Right Cessation
-
2006
- 2006-02-06 EP EP06708050A patent/EP1846384B1/en not_active Expired - Lifetime
- 2006-02-06 AT AT06708050T patent/ATE402154T1/de active
- 2006-02-06 MX MX2007009574A patent/MX2007009574A/es active IP Right Grant
- 2006-02-06 DE DE602006001938T patent/DE602006001938D1/de not_active Expired - Lifetime
- 2006-02-06 CN CN200680008857.1A patent/CN101155793B/zh not_active Expired - Lifetime
- 2006-02-06 ES ES06708050T patent/ES2309948T3/es not_active Expired - Lifetime
- 2006-02-06 CA CA2597016A patent/CA2597016C/en not_active Expired - Lifetime
- 2006-02-06 US US11/815,736 patent/US8207197B2/en active Active
- 2006-02-06 RS RSP-2008/0482A patent/RS50624B/sr unknown
- 2006-02-06 PL PL06708050T patent/PL1846384T3/pl unknown
- 2006-02-06 HR HR20080446T patent/HRP20080446T3/xx unknown
- 2006-02-06 PT PT06708050T patent/PT1846384E/pt unknown
- 2006-02-06 DK DK06708050T patent/DK1846384T3/da active
- 2006-02-06 ME MEP-2008-394A patent/ME01103B/me unknown
- 2006-02-06 SI SI200630073T patent/SI1846384T1/sl unknown
- 2006-02-06 JP JP2007554541A patent/JP5072604B2/ja not_active Expired - Lifetime
- 2006-02-06 WO PCT/EP2006/050703 patent/WO2006084833A1/en not_active Ceased
- 2006-02-08 AR ARP060100448A patent/AR054734A1/es not_active Application Discontinuation
- 2006-02-08 TW TW095104184A patent/TWI393711B/zh not_active IP Right Cessation
- 2006-02-09 UY UY29369A patent/UY29369A1/es not_active Application Discontinuation
-
2007
- 2007-09-06 KR KR1020077020422A patent/KR101344271B1/ko not_active Expired - Lifetime
-
2008
- 2008-10-21 CY CY20081101174T patent/CY1108428T1/el unknown
-
2012
- 2012-06-07 US US13/491,229 patent/US8354430B2/en not_active Expired - Lifetime
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