JP2008527027A - 炎症の治療に有用なインドール類 - Google Patents

炎症の治療に有用なインドール類 Download PDF

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JP2008527027A
JP2008527027A JP2007551725A JP2007551725A JP2008527027A JP 2008527027 A JP2008527027 A JP 2008527027A JP 2007551725 A JP2007551725 A JP 2007551725A JP 2007551725 A JP2007551725 A JP 2007551725A JP 2008527027 A JP2008527027 A JP 2008527027A
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JP2008527027A5 (https=
Inventor
ベンジャミン ペルクマン，
クリストファー オロフッソン，
マーティンス カツケヴィックス，
ヴィータ オゾラ，
エドガース スナ，
イバース カルヴィンス，
ピーテリス トラペンシーリス，
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Biolipox AB
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Biolipox AB
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    • C—CHEMISTRY; METALLURGY
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Biotechnology (AREA)
JP2007551725A 2005-01-19 2005-12-22 炎症の治療に有用なインドール類 Withdrawn JP2008527027A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64455405P 2005-01-19 2005-01-19
US64455305P 2005-01-19 2005-01-19
PCT/GB2005/004978 WO2006077364A1 (en) 2005-01-19 2005-12-22 Indoles useful in the treatment of inflammation

Publications (2)

Publication Number Publication Date
JP2008527027A true JP2008527027A (ja) 2008-07-24
JP2008527027A5 JP2008527027A5 (https=) 2009-02-19

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ID=36001052

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Application Number Title Priority Date Filing Date
JP2007551725A Withdrawn JP2008527027A (ja) 2005-01-19 2005-12-22 炎症の治療に有用なインドール類

Country Status (7)

Country Link
US (1) US20080249091A1 (https=)
EP (1) EP1844013A1 (https=)
JP (1) JP2008527027A (https=)
AR (1) AR053993A1 (https=)
CA (1) CA2594878A1 (https=)
TW (1) TW200637820A (https=)
WO (1) WO2006077364A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011019060A1 (ja) * 2009-08-12 2011-02-17 協和発酵キリン株式会社 ヘッジホッグシグナル阻害剤
CN109665985A (zh) * 2018-11-30 2019-04-23 中国科学院广州生物医药与健康研究院 多取代吲哚类化合物及其应用

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA06014535A (es) * 2004-06-18 2007-06-05 Biolipox Ab Indoles utiles en el tratamiento de la inflamacion.
DE602005014233D1 (de) * 2004-06-18 2009-06-10 Biolipox Ab Zur behandlung von entzündungen geeignete indole
RU2007101703A (ru) * 2004-06-18 2008-07-27 Биолипокс Аб (Se) Индолы, полезные при лечении воспаления
BRPI0519774A2 (pt) * 2005-01-19 2009-02-10 Biolipox Ab composto ou um sal farmaceuticamente aceitÁvel do mesmo, formulaÇço farmacÊutica, uso de um composto ou um sal farmaceuticamente aceitÁvel do mesmo, mÉtodo de tratamento de uma doenÇa em que inibiÇço da atividade de um membro da famÍlia mapeg É desejada e/ou necessÁria, produto combinado, e, processo para a preparaÇço de um composto
JP2008527030A (ja) * 2005-01-19 2008-07-24 バイオリポックス エービー 炎症の治療に有用なインドール類
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
WO2008009924A2 (en) * 2006-07-18 2008-01-24 Biolipox Ab Indoles useful in the treatment of inflammation
CN101157688B (zh) * 2006-10-16 2010-09-08 复旦大学 6-苄氧基吲哚-2-甲酸糠醇酯衍生物及其制备方法和用途
CN101679248A (zh) 2007-03-29 2010-03-24 阿斯比奥制药株式会社 具有cPLA2抑制活性的吲哚衍生物及其用途以及制备方法
TW200920369A (en) 2007-10-26 2009-05-16 Amira Pharmaceuticals Inc 5-lipoxygenase activating protein (flap) inhibitor
JP5791500B2 (ja) 2008-05-23 2015-10-07 パンミラ ファーマシューティカルズ，エルエルシー． ５−リポキシゲナーゼ活性化タンパク質阻害剤
US8546431B2 (en) 2008-10-01 2013-10-01 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
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