JP2008523102A5 - - Google Patents
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- Publication number
- JP2008523102A5 JP2008523102A5 JP2007545718A JP2007545718A JP2008523102A5 JP 2008523102 A5 JP2008523102 A5 JP 2008523102A5 JP 2007545718 A JP2007545718 A JP 2007545718A JP 2007545718 A JP2007545718 A JP 2007545718A JP 2008523102 A5 JP2008523102 A5 JP 2008523102A5
- Authority
- JP
- Japan
- Prior art keywords
- carbon atoms
- pharmaceutical composition
- alkyl
- hydrogen atom
- pde4 modulator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 0 CCN(C(*)*C)C(C)=O Chemical compound CCN(C(*)*C)C(C)=O 0.000 description 3
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63498204P | 2004-12-13 | 2004-12-13 | |
| PCT/US2005/045071 WO2006065814A1 (en) | 2004-12-13 | 2005-12-12 | Compositions comprising pde4 modulators and their use for the treatment or prevention of airway inflammation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008523102A JP2008523102A (ja) | 2008-07-03 |
| JP2008523102A5 true JP2008523102A5 (https=) | 2009-02-12 |
Family
ID=36121316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007545718A Abandoned JP2008523102A (ja) | 2004-12-13 | 2005-12-12 | Ｐｄｅ４モジュレーターを含有する組成物及び気道炎症の治療又は予防のためのそれらの使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20060148882A1 (https=) |
| EP (1) | EP1838294A1 (https=) |
| JP (1) | JP2008523102A (https=) |
| KR (1) | KR20070092276A (https=) |
| CN (1) | CN101111235A (https=) |
| AR (1) | AR052047A1 (https=) |
| AU (1) | AU2005316593A1 (https=) |
| BR (1) | BRPI0519030A2 (https=) |
| CA (1) | CA2590903A1 (https=) |
| IL (1) | IL183858A0 (https=) |
| MX (1) | MX2007006992A (https=) |
| WO (1) | WO2006065814A1 (https=) |
| ZA (1) | ZA200705540B (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050100529A1 (en) * | 2003-11-06 | 2005-05-12 | Zeldis Jerome B. | Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of asbestos-related diseases and disorders |
| US20050239867A1 (en) * | 2004-04-23 | 2005-10-27 | Zeldis Jerome B | Methods of using and compositions comprising PDE4 modulators for the treatment and management of pulmonary hypertension |
| WO2007045980A1 (en) * | 2005-10-19 | 2007-04-26 | Ranbaxy Laboratories Limited | Compositions of phosphodiesterase type iv inhibitors |
| PE20120580A1 (es) * | 2009-02-10 | 2012-05-23 | Celgene Corp | Metodos para utilizar y composiciones que comprenden moduladores pde4 para tratamiento, prevencion y control de tuberculosis |
| BRPI1012770B8 (pt) | 2009-05-14 | 2021-05-25 | Tianjin Hemay Bio Tech Co Ltd | derivados de tiofeno |
| MX341050B (es) * | 2010-04-07 | 2016-08-05 | Celgene Corp * | Metodos para tratar infeccion viral respiratoria. |
| WO2012083017A2 (en) | 2010-12-16 | 2012-06-21 | Celgene Corporation | Controlled release oral dosage forms of poorly soluble drugs and uses thereof |
| WO2012096859A2 (en) * | 2011-01-10 | 2012-07-19 | Celgene Corporation | Oral dosage forms of cyclopropanecarboxylic acid {2-[(1s)-1-(3-ethoxy-4-methoxy-phenyl]-2-methanesulfonyl-ethyl]-3-oxo-2,3-dihydro-1h-isoindol-4-yl}-amide |
| MX347928B (es) | 2011-01-10 | 2017-05-19 | Celgene Corp | Derivados de fenetilsulfona isoindolina y su uso. |
| WO2012121988A2 (en) | 2011-03-07 | 2012-09-13 | Celgene Corporation | Methods for treating diseases using isoindoline compounds |
| CN103635188B (zh) | 2011-04-28 | 2017-03-22 | 细胞基因公司 | 使用pde4抑制剂用于治疗和控制自身免疫性疾病和炎性疾病的方法和组合物 |
| CN105050624A (zh) | 2013-03-14 | 2015-11-11 | 细胞基因公司 | 利用阿普斯特来治疗银屑病关节炎的方法 |
| WO2015112568A1 (en) * | 2014-01-24 | 2015-07-30 | Celgene Corporation | Methods for the treatment of obesity using apremilast |
| US10092541B2 (en) | 2014-08-15 | 2018-10-09 | Celgene Corporation | Methods for the treatment of diseases ameliorated by PDE4 inhibition using dosage titration of apremilast |
| WO2017030892A1 (en) | 2015-08-14 | 2017-02-23 | Reaction Biology Corp. | Histone deacetylase inhibitors and methods for use thereof |
| RU2743126C9 (ru) * | 2016-08-22 | 2021-04-27 | Шицзячжуан Сагесити Нью Драг Дивелопмент Ко., Лтд. | Ингибитор pde4 |
| KR102318401B1 (ko) * | 2017-02-28 | 2021-10-29 | 강푸 바이오파마슈티칼즈 리미티드 | 신규한 이소인돌린 유도체, 이의 약학 조성물 및 용도 |
| AU2018234059A1 (en) * | 2017-03-16 | 2019-10-31 | Takeda Gmbh | Treatment of idiopathic pulmonary fibrosis |
| GB202306663D0 (en) | 2023-05-05 | 2023-06-21 | Union Therapeutics As | Combination therapy |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6020358A (en) * | 1998-10-30 | 2000-02-01 | Celgene Corporation | Substituted phenethylsulfones and method of reducing TNFα levels |
| US6667316B1 (en) * | 1999-11-12 | 2003-12-23 | Celgene Corporation | Pharmaceutically active isoindoline derivatives |
| US6699899B1 (en) * | 1999-12-21 | 2004-03-02 | Celgene Corporation | Substituted acylhydroxamic acids and method of reducing TNFα levels |
| US6962940B2 (en) * | 2002-03-20 | 2005-11-08 | Celgene Corporation | (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof |
| US7276529B2 (en) * | 2002-03-20 | 2007-10-02 | Celgene Corporation | Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione |
| EP1567154A4 (en) * | 2002-11-06 | 2006-05-31 | Celgene Corp | METHODS AND COMPOSITIONS USING CYTOKINE SELECTIVE INHIBITION DRUGS FOR TREATING AND CONTROLLING CANCERS AND OTHER DISEASES |
| JP2006510617A (ja) * | 2002-11-18 | 2006-03-30 | セルジーン・コーポレーション | （＋）−３−（３，４−ジメトキシ−フェニル）−３−（１−オキソ−１，３−ジヒドロ−イソインドール−２−イル）−プロピオンアミドの使用方法およびそれを含む組成物 |
| DE60330187D1 (de) * | 2002-12-30 | 2009-12-31 | Celgene Corp | Fluoralkoxy-substituierte 1, 3-dihydro-isoindolyl-verbindungen und ihre pharmazeutischen verwendungen |
| US20050239867A1 (en) * | 2004-04-23 | 2005-10-27 | Zeldis Jerome B | Methods of using and compositions comprising PDE4 modulators for the treatment and management of pulmonary hypertension |
| AU2004319815A1 (en) * | 2004-05-05 | 2005-12-01 | Celgene Corporation | Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases |
| US7244759B2 (en) * | 2004-07-28 | 2007-07-17 | Celgene Corporation | Isoindoline compounds and methods of making and using the same |
-
2005
- 2005-12-12 CA CA002590903A patent/CA2590903A1/en not_active Abandoned
- 2005-12-12 MX MX2007006992A patent/MX2007006992A/es unknown
- 2005-12-12 AU AU2005316593A patent/AU2005316593A1/en not_active Abandoned
- 2005-12-12 WO PCT/US2005/045071 patent/WO2006065814A1/en not_active Ceased
- 2005-12-12 EP EP05853888A patent/EP1838294A1/en not_active Withdrawn
- 2005-12-12 JP JP2007545718A patent/JP2008523102A/ja not_active Abandoned
- 2005-12-12 KR KR1020077015958A patent/KR20070092276A/ko not_active Withdrawn
- 2005-12-12 BR BRPI0519030-4A patent/BRPI0519030A2/pt not_active IP Right Cessation
- 2005-12-12 ZA ZA200705540A patent/ZA200705540B/xx unknown
- 2005-12-12 CN CNA2005800476591A patent/CN101111235A/zh active Pending
- 2005-12-13 US US11/299,702 patent/US20060148882A1/en not_active Abandoned
- 2005-12-13 AR ARP050105222A patent/AR052047A1/es not_active Application Discontinuation
-
2007
- 2007-06-12 IL IL183858A patent/IL183858A0/en unknown
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