JP2008522604A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008522604A5 JP2008522604A5 JP2007544987A JP2007544987A JP2008522604A5 JP 2008522604 A5 JP2008522604 A5 JP 2008522604A5 JP 2007544987 A JP2007544987 A JP 2007544987A JP 2007544987 A JP2007544987 A JP 2007544987A JP 2008522604 A5 JP2008522604 A5 JP 2008522604A5
- Authority
- JP
- Japan
- Prior art keywords
- analysis
- neural network
- sepsis
- inf
- sirs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims description 12
- 238000004458 analytical method Methods 0.000 claims description 10
- 238000000540 analysis of variance Methods 0.000 claims description 4
- 238000000491 multivariate analysis Methods 0.000 claims description 2
- 238000013528 artificial neural network Methods 0.000 claims 7
- 206010040047 Sepsis Diseases 0.000 claims 6
- 238000003757 reverse transcription PCR Methods 0.000 claims 5
- 206010051379 Systemic Inflammatory Response Syndrome Diseases 0.000 claims 4
- 239000000090 biomarker Substances 0.000 claims 4
- 238000007619 statistical method Methods 0.000 claims 3
- 101710155857 C-C motif chemokine 2 Proteins 0.000 claims 2
- 102100021943 C-C motif chemokine 2 Human genes 0.000 claims 2
- 108010039471 Fas Ligand Protein Proteins 0.000 claims 2
- -1 IL-1β Proteins 0.000 claims 2
- 108090000174 Interleukin-10 Proteins 0.000 claims 2
- 108090001005 Interleukin-6 Proteins 0.000 claims 2
- 108090001007 Interleukin-8 Proteins 0.000 claims 2
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 2
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims 2
- 102100031988 Tumor necrosis factor ligand superfamily member 6 Human genes 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 2
- 238000000513 principal component analysis Methods 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 239000011159 matrix material Substances 0.000 description 2
- 238000001134 F-test Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0426982.5A GB0426982D0 (en) | 2004-12-09 | 2004-12-09 | Early detection of sepsis |
| PCT/GB2005/004755 WO2006061644A1 (en) | 2004-12-09 | 2005-12-09 | Early detection of sepsis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008522604A JP2008522604A (ja) | 2008-07-03 |
| JP2008522604A5 true JP2008522604A5 (https=) | 2012-02-23 |
Family
ID=34073429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007544987A Pending JP2008522604A (ja) | 2004-12-09 | 2005-12-09 | 敗血症の早期検出 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20080114576A1 (https=) |
| EP (2) | EP2458517A1 (https=) |
| JP (1) | JP2008522604A (https=) |
| CN (1) | CN101076806B (https=) |
| AU (1) | AU2005313114B2 (https=) |
| CA (1) | CA2587270A1 (https=) |
| GB (1) | GB0426982D0 (https=) |
| WO (1) | WO2006061644A1 (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9053222B2 (en) | 2002-05-17 | 2015-06-09 | Lawrence A. Lynn | Patient safety processor |
| US7191068B2 (en) * | 2003-03-25 | 2007-03-13 | Proteogenix, Inc. | Proteomic analysis of biological fluids |
| US8068990B2 (en) * | 2003-03-25 | 2011-11-29 | Hologic, Inc. | Diagnosis of intra-uterine infection by proteomic analysis of cervical-vaginal fluids |
| CA2605143A1 (en) | 2005-04-15 | 2006-10-26 | Becton, Dickinson And Company | Diagnosis of sepsis |
| US20090297474A1 (en) * | 2005-11-25 | 2009-12-03 | Dermot Kelleher | Method for Detecting or Monitoring Sepsis by Analysing Cytokine mRNA Expression Levels |
| WO2007069450A1 (ja) | 2005-12-14 | 2007-06-21 | Nec Corporation | ディジタル通信システム、屋内装置及び屋外装置 |
| GB0610078D0 (en) * | 2006-05-20 | 2006-06-28 | Secr Defence | Sepsis detection microarray |
| EP1950310A1 (en) * | 2007-01-23 | 2008-07-30 | Charite-Universitätsmedizin Berlin | Method for risk prediction of a postoperative sepsis in a human |
| GB0722582D0 (en) * | 2007-11-16 | 2007-12-27 | Secr Defence | Early detection of sepsis |
| US8669113B2 (en) | 2008-04-03 | 2014-03-11 | Becton, Dickinson And Company | Advanced detection of sepsis |
| EP2283443A1 (en) | 2008-05-07 | 2011-02-16 | Lynn, Lawrence A. | Medical failure pattern search engine |
| US11728041B2 (en) * | 2008-05-07 | 2023-08-15 | Lawrence A. Lynn | Real-time time series matrix pathophysiologic pattern processor and quality assessment method |
| EP2166358A1 (en) * | 2008-09-17 | 2010-03-24 | Fundacio Institut de Recerca de l'Hospital Universitari Vall d'Hebron | Differential diagnostic biomarkers of stroke mimicking conditions and methods of use thereof |
| WO2010088610A2 (en) * | 2009-01-31 | 2010-08-05 | Mayo Foundation For Medical Education And Research | Presentation of critical patient data |
| JP5667353B2 (ja) * | 2009-09-25 | 2015-02-12 | シスメックス株式会社 | 血球計数装置、診断支援装置、診断支援方法及びコンピュータプログラム |
| WO2011116872A1 (en) | 2010-03-02 | 2011-09-29 | Roche Diagnostics Gmbh | Il-6 detection based early diagnosis and prediction of systemic inflammatory response syndrome and sepsis in asymptomatic patients |
| US9719842B2 (en) * | 2010-07-06 | 2017-08-01 | Norman A. Paradis | Method for the discovery, validation and clinical application of multiplex biomarker algorithms based on optical, physical and/or electromagnetic patterns |
| US20140037649A1 (en) * | 2010-11-26 | 2014-02-06 | Immunexpress Pty Ltd | Diagnostic and/or screening agents and uses therefor |
| US20140120174A1 (en) * | 2012-10-30 | 2014-05-01 | Lascco, Sa | Methods of prognosis and diagnosis of sepsis |
| US10354429B2 (en) | 2012-11-14 | 2019-07-16 | Lawrence A. Lynn | Patient storm tracker and visualization processor |
| US9953453B2 (en) | 2012-11-14 | 2018-04-24 | Lawrence A. Lynn | System for converting biologic particle density data into dynamic images |
| US20150362509A1 (en) * | 2013-01-28 | 2015-12-17 | Vanderbilt University | Method for Differentiating Sepsis and Systemic Inflammatory Response Syndrome (SIRS) |
| WO2014134522A1 (en) | 2013-02-28 | 2014-09-04 | Lynn Lawrence A | System and method for generating quaternary images of biologic force propagation and recovery |
| KR101595784B1 (ko) * | 2013-05-31 | 2016-02-26 | 가톨릭대학교 산학협력단 | 패혈증 고위험군 예측 방법 및 시스템 |
| US20160244834A1 (en) * | 2013-06-28 | 2016-08-25 | Acumen Research Laboratories Pte. Ltd. | Sepsis biomarkers and uses thereof |
| US10260111B1 (en) | 2014-01-20 | 2019-04-16 | Brett Eric Etchebarne | Method of detecting sepsis-related microorganisms and detecting antibiotic-resistant sepsis-related microorganisms in a fluid sample |
| GB201402293D0 (en) | 2014-02-11 | 2014-03-26 | Secr Defence | Biomarker signatures for the prediction of onset of sepsis |
| AU2015323511B2 (en) * | 2014-09-26 | 2019-10-03 | Sofradim Production | System and method for early detection of post-surgery infection |
| US10761093B2 (en) | 2014-10-09 | 2020-09-01 | Texas Tech University System | Microdevice for cell separation utilizing activation phenotype |
| EP3371747B1 (en) | 2015-12-10 | 2023-07-19 | Deepmind Technologies Limited | Augmenting neural networks with external memory |
| US11114205B2 (en) * | 2016-01-28 | 2021-09-07 | Beckman Coulter, Inc. | Infection detection and differentiation systems and methods |
| US20230187067A1 (en) * | 2016-03-23 | 2023-06-15 | Peach Intellihealth, Inc. | Use of clinical parameters for the prediction of sirs |
| CN111989032B (zh) * | 2018-06-15 | 2024-07-19 | 拜克门寇尔特公司 | 存在母细胞标志时确定败血症的方法 |
| CN111374639A (zh) * | 2018-12-28 | 2020-07-07 | 陈柏龄 | 败血症的菌种预测系统与方法 |
| KR102287968B1 (ko) * | 2019-03-29 | 2021-08-09 | 연세대학교 산학협력단 | 균혈증 발병 위험도 예측 방법 및 이를 이용한 균혈증 발병 위험도 예측용 디바이스 |
| WO2020257358A1 (en) * | 2019-06-17 | 2020-12-24 | The Broad Institute, Inc. | Immune cell signature for bacterial sepsis |
| CN114127861A (zh) * | 2019-07-12 | 2022-03-01 | 贝克曼库尔特有限公司 | 使用包括收缩压、血液学参数及其组合的生命体征检测败血症的方法 |
| WO2021026123A1 (en) * | 2019-08-06 | 2021-02-11 | Beckman Coulter, Inc. | Detecting and reporting subpopulations of neutrophils |
| US20210059597A1 (en) * | 2019-08-30 | 2021-03-04 | Hill-Rom Services, Inc. | Sepsis monitoring system |
| WO2021102776A1 (zh) * | 2019-11-28 | 2021-06-03 | 北京肿瘤医院(北京大学肿瘤医院) | 一种用于早期体腔内感染性并发症诊断的标记物及方法 |
| AU2020411504B2 (en) * | 2019-12-27 | 2024-04-18 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Predicting and addressing severe disease in individuals with sepsis |
| JP2023509786A (ja) * | 2020-01-10 | 2023-03-09 | プレノシス，インコーポレイテッド | 適合率診断において関連する特徴を選択するためのツール |
| US20230040185A1 (en) * | 2020-01-10 | 2023-02-09 | Prenosis, Inc. | A time-sensitive trigger for a streaming data environment |
| CN114167062B (zh) * | 2020-09-10 | 2024-02-02 | 北京肿瘤医院(北京大学肿瘤医院) | 一种用于早期腹腔内感染性并发症诊断的标记物及方法 |
| TWI803893B (zh) * | 2021-06-28 | 2023-06-01 | 中國醫藥大學 | 敗血症之人工智慧輔助醫療診斷方法及其系統 |
| DE102022114248A1 (de) | 2022-06-07 | 2023-12-07 | TCC GmbH | Verfahren sowie Vorhersagesystem zur Ermittlung der Eintrittswahrscheinlichkeit einer Sepsis eines Patienten |
| CN120526862A (zh) * | 2025-07-24 | 2025-08-22 | 中国疾病预防控制中心传染病预防控制所 | 一种基于5种标记物的感染病原体类型检测系统 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6190872B1 (en) * | 1994-05-06 | 2001-02-20 | Gus J. Slotman | Method for identifying and monitoring patients at risk for systemic inflammatory conditions and apparatus for use in this method |
| US6804551B2 (en) | 1998-03-17 | 2004-10-12 | University Of Virginia Patent Foundation | Method and apparatus for the early diagnosis of subacute, potentially catastrophic illness |
| WO2000010455A1 (en) * | 1998-08-24 | 2000-03-02 | Emory University | Method and apparatus for predicting the onset of seizures based on features derived from signals indicative of brain activity |
| AU3862200A (en) * | 1999-03-01 | 2000-09-21 | Board Of Trustees Of The Leland Stanford Junior University | Rapid assay for infection in small children |
| DE10155600B4 (de) * | 2001-11-09 | 2009-08-27 | Oligene Gmbh | Nukleinsäure-Array |
| US20040038201A1 (en) * | 2002-01-22 | 2004-02-26 | Whitehead Institute For Biomedical Research | Diagnostic and therapeutic applications for biomarkers of infection |
| US7774143B2 (en) * | 2002-04-25 | 2010-08-10 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Methods for analyzing high dimensional data for classifying, diagnosing, prognosticating, and/or predicting diseases and other biological states |
| WO2004044555A2 (en) * | 2002-11-12 | 2004-05-27 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
| WO2004044556A2 (en) * | 2002-11-12 | 2004-05-27 | Becton, Dickinson And Company | Diagnosis of sepsis or sirs using biomarker profiles |
| US20040096917A1 (en) * | 2002-11-12 | 2004-05-20 | Becton, Dickinson And Company | Diagnosis of sepsis or SIRS using biomarker profiles |
| JP2007518062A (ja) * | 2003-09-29 | 2007-07-05 | バイオサイト インコーポレイテッド | 敗血症を診断する方法および診断するための組成物 |
| TW200519384A (en) * | 2003-12-12 | 2005-06-16 | We Gene Technologies Inc | Sepsis detection chip and fabricating method thereof and method of detecting sepsis |
| US20050196817A1 (en) * | 2004-01-20 | 2005-09-08 | Molecular Staging Inc. | Biomarkers for sepsis |
| GB0610078D0 (en) * | 2006-05-20 | 2006-06-28 | Secr Defence | Sepsis detection microarray |
-
2004
- 2004-12-09 GB GBGB0426982.5A patent/GB0426982D0/en not_active Ceased
-
2005
- 2005-12-09 AU AU2005313114A patent/AU2005313114B2/en not_active Ceased
- 2005-12-09 US US11/792,724 patent/US20080114576A1/en not_active Abandoned
- 2005-12-09 WO PCT/GB2005/004755 patent/WO2006061644A1/en not_active Ceased
- 2005-12-09 EP EP11008209A patent/EP2458517A1/en not_active Withdrawn
- 2005-12-09 JP JP2007544987A patent/JP2008522604A/ja active Pending
- 2005-12-09 EP EP05825137A patent/EP1839218A1/en not_active Withdrawn
- 2005-12-09 CN CN2005800424703A patent/CN101076806B/zh not_active Expired - Fee Related
- 2005-12-09 CA CA002587270A patent/CA2587270A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008522604A5 (https=) | ||
| Cope et al. | A benchmark for Affymetrix GeneChip expression measures | |
| JP4610196B2 (ja) | リアルタイムｐｃｒのための自動閾値設定およびベースライン決定 | |
| US9607128B2 (en) | Detection and correction of jumps in real-time PCR signals | |
| WO2010139812A4 (en) | miRNA FINGERPRINT IN THE DIAGNOSIS OF DISEASES | |
| KR101828052B1 (ko) | 유전자의 복제수 변이(cnv)를 분석하는 방법 및 장치 | |
| JP2011504723A (ja) | ゲノム同定システム | |
| HK1257433A1 (zh) | 免疫組庫正常性評估方法及其應用 | |
| EP3353697B1 (en) | Multiple dataset analysis for determining the presence or absence of target analyte | |
| WO2014065155A1 (ja) | ネットワークエントロピーに基づく生体の状態遷移の予兆の検出を支援する検出装置、検出方法及び検出プログラム | |
| Bybjerg-Grauholm et al. | RNA sequencing of archived neonatal dried blood spots | |
| KR101771402B1 (ko) | 핵산 정량 방법 | |
| US20180196924A1 (en) | Computer-implemented method and system for diagnosis of biological conditions of a patient | |
| Osman et al. | Consistency in rates of diagnosis of embryonic mosaicism, segmental abnormalities, and “no call” results among experienced embryologists performing preimplantation genetic testing for aneuploidy | |
| Sadler et al. | Application of a new highly multiplexed amplicon sequencing tool to evaluate Plasmodium falciparum antimalarial resistance and relatedness in individual and pooled samples from Dschang, Cameroon | |
| CN115747315A (zh) | 基于聚合酶链式反应的检测控制方法、装置和计算机设备 | |
| Aimone et al. | Unbiased characterization of high-density oligonucleotide microarrays using probe-level statistics | |
| US20240076751A1 (en) | Variant classification through high-confidence mutation detection from fluorescence signals measured with a multiple mutation assay | |
| CN114566224A (zh) | 一种用于鉴别或区分不同海拔人群的模型及其应用 | |
| Lindig et al. | Age-independent co-expression of antimicrobial gene clusters in the blood of septic patients | |
| Kuśmirek et al. | Clustering-based optimization method of reference set selection for improved CNV callers performance | |
| CN118813782B (zh) | 一种高血压预警模型、产品、计算机可读存储介质及其应用 | |
| US20240344130A1 (en) | Isothermal amplification-based diagnosis and treatment of acute infection | |
| Lydon et al. | Generation and Analysis of Host Transcriptomics and Development of Host‐Response Based Signatures | |
| HK40084342A (en) | Immunorepertoire normality assessment method and its use |