SG11201807719SA - Use of clinical parameters for the prediction of sirs - Google Patents

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1111111011111111101 IIIIIIIIIIIIIIIIIII1011101111IIIIIIIIIIIIIIIIII101111111011011111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2017/165693 A4 28 September 2017 (28.09.2017) W I P0 I P C T (51) International Patent Classification: gi; 45 Willard Road, Weston, MA 02493 (US). TIDOR, GO1N 33/53 (2006.01) C12Q 1/68 (2006.01) Bruce; 6 Stevens Road, Lexington, MA 02421 (US). G01N 33/50 (2006.01) GOOF 19/00 (2011.01) (74) Agent: GORDON, Edward A.; McDermott Will & Emery (21) International Application Number: LLP, 500 North Capitol Street, N.W., Washington, D.C. PCT/US2017/023885 20001 (US). (22) International Filing Date: (81) Designated States (unless otherwise indicated, for every 23 March 2017 (23.03.2017) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, (25) Filing Language: English CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, (26) Publication Language: English DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, (30) Priority Data: KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, 62/312,339 23 March 2016 (23.03.2016) US MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, (71) Applicant: PEACH INTELLIHEALTH, INC. [US/US]; PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, 124 W. 60th Street, #49c, New York, NY 10023 (US). SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (72) Inventors: HONG, L.S, Klaudyne; 124 W. 60th Street, #49c, New York, NY 10023 (US). WOGAN, Gerald; 125 (84) Designated States (unless otherwise indicated, for every Claflin Street, Belmont, MA 02478 (US). VACCA, Lui- kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, = (54) Title: USE OF CLINICAL PARAMETERS FOR THE PREDICTION OF SIRS = FIG. 1 ,-- e 102a--, = = 0 --„, a 1 = = = = = 102c-N,„ = = _ = _ Li ica io ii- System 100 Cr) 01 (57) : A system for disease prediction includes processing circuitry configured to receive a dataset including data of a patient l() population, the data including for each of a plurality of patients of the patient population, values for a plurality of features, and a diagnosis value indicating whether a disease has been diagnosed. The processing circuitry is configured to, based on correlations between the 1-1 ---- values, select from the dataset a plurality of subsets of the features, and, for each of at least one of the subsets, execute a machine learning IN process with the respective subset and the diagnosis values as input parameters, the execution generating a respective prediction model. © The processing circuitry is configured to output the respective prediction model. ei O [Continued on next page] WO 2017/165693 A4 MIDEDIMOMOIDEIROIDEMOMMEMEMINHIMEHMIE UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — with amended claims (Art. 19(1)) Date of publication of the amended claims: 14 December 2017 (14.12.2017)