JP2008521488A5 - - Google Patents
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- Publication number
- JP2008521488A5 JP2008521488A5 JP2007543080A JP2007543080A JP2008521488A5 JP 2008521488 A5 JP2008521488 A5 JP 2008521488A5 JP 2007543080 A JP2007543080 A JP 2007543080A JP 2007543080 A JP2007543080 A JP 2007543080A JP 2008521488 A5 JP2008521488 A5 JP 2008521488A5
- Authority
- JP
- Japan
- Prior art keywords
- spray
- nasal
- olopatadine
- formulation
- span
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007921 spray Substances 0.000 claims 12
- JBIMVDZLSHOPLA-LSCVHKIXSA-N Olopatadine Chemical compound C1OC2=CC=C(CC(O)=O)C=C2C(=C/CCN(C)C)\C2=CC=CC=C21 JBIMVDZLSHOPLA-LSCVHKIXSA-N 0.000 claims 9
- 238000009472 formulation Methods 0.000 claims 9
- 239000000203 mixture Substances 0.000 claims 9
- 229960004114 olopatadine Drugs 0.000 claims 9
- 229940097496 Nasal Spray Drugs 0.000 claims 3
- 239000007922 nasal spray Substances 0.000 claims 3
- 238000002347 injection Methods 0.000 claims 2
- 239000007924 injection Substances 0.000 claims 2
- 206010020751 Hypersensitivity Diseases 0.000 claims 1
- 206010028741 Nasal inflammation Diseases 0.000 claims 1
- 201000005794 allergic hypersensitivity disease Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000005507 spraying Methods 0.000 claims 1
Claims (12)
- オロパタジン(olopatadine)を含む配合物を収容するボトルを有する鼻用噴霧器であって、
２０−４５ｍｍの最長軸、１４−２０ｍｍの最短軸、および１−１８の長円率を有する噴霧パターン、ならびに／または
１５−３０μｍのＤ１０、３０−６０μｍのＤ５０、５０−１５０μｍのＤ９０、３よりも大きくないスパン（ＳＰＡＮ）を有し、かつ容量％＜１０μｍが４％未満である小滴寸法分布、
の少なくとも一方を含む噴霧特性を有する前記配合物の噴霧を噴射できる構成の鼻用噴霧器。 - 前記最長軸が２３．５ｍｍである噴霧特性を有する、請求項１の鼻用噴霧器。
- 前記最短軸は１７．５ｍｍである噴霧特性を有する、請求項１の鼻用噴霧器。
- 前記長円率は１−１４である噴霧特性を有する、請求項１の鼻用噴霧器。
- 前記配合物は０．３８−０．６２％オロパタジンを含む、請求項１の鼻用噴霧器。
- 前記配合物は０．６％オロパタジンを含む、請求項５の鼻用噴霧器。
- 前記噴霧特性は９０−１１０ｍｇの射出重量を更に含む、請求項１の鼻用噴霧器。
- Ｄ１０が１８−２５μｍ、Ｄ５０が３９−５３μｍ、Ｄ９０が８３−１２８μｍ、スパンが１．６−２．１、および容量％＜１０μｍが０．８−２．４％である小滴寸法分布を有する、請求項１の鼻用噴霧器。
- Ｄ１０が１８−２５μｍであり、Ｄ５０が３９−５３μｍであり、Ｄ９０が８３−１２８μｍであり、スパンが１．６−２．１であり、容量％＜１０μｍが０．８−２．４％である小滴寸法分布を有し、前記配合物が０．６％オロパタジンを含み、かつ前記噴霧特性が９０−１１０ｍｇの射出重量を更に含む、請求項１の鼻用噴霧器。
- 鼻のアレルギーまたは鼻炎症状の治療に利用される鼻用噴霧器の製造においてオロパタジンを使用する方法であって、
オロパタジン配合物を収容するボトルを鼻用噴霧器に連結し、かつ
２０−４５ｍｍの最長軸、１４−２０ｍｍの最短軸、および１−１８の長円率を有する噴霧パターン、ならびに／または
１５−３０μｍのＤ１０、３０−６０μｍのＤ５０、５０−１５０μｍのＤ９０、３よりも大きくないスパン（ＳＰＡＮ）を有し、かつ容量％＜１０μｍが４％未満である小滴寸法分布、
の少なくとも一方を含む噴霧特性を有する前記配合物の噴霧を噴射するように前記鼻用噴霧器を構成することを含む、使用法。 - ０．３８−０．６２％オロパタジンを含む配合物としてオロパタジンを提供する、請求項１０の使用法。
- 前記配合物が０．６％オロパタジンを含む、請求項１１の使用法。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63088604P | 2004-11-24 | 2004-11-24 | |
| US60/630,886 | 2004-11-24 | ||
| PCT/US2005/039268 WO2006057769A2 (en) | 2004-11-24 | 2005-10-31 | Method of delivering nasal spray |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008521488A JP2008521488A (ja) | 2008-06-26 |
| JP2008521488A5 true JP2008521488A5 (ja) | 2008-11-13 |
| JP5068172B2 JP5068172B2 (ja) | 2012-11-07 |
Family
ID=36498400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007543080A Active JP5068172B2 (ja) | 2004-11-24 | 2005-10-31 | 鼻に噴霧を噴射する方法 |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US20060110328A1 (ja) |
| EP (1) | EP1814538B1 (ja) |
| JP (1) | JP5068172B2 (ja) |
| KR (1) | KR101158603B1 (ja) |
| CN (2) | CN101065122A (ja) |
| AT (1) | ATE443516T1 (ja) |
| AU (1) | AU2005309951B2 (ja) |
| BR (1) | BRPI0518283A2 (ja) |
| CA (1) | CA2586553C (ja) |
| CY (1) | CY1110528T1 (ja) |
| DE (1) | DE602005016833D1 (ja) |
| DK (1) | DK1814538T3 (ja) |
| ES (1) | ES2331619T3 (ja) |
| MX (1) | MX2007005845A (ja) |
| PL (1) | PL1814538T3 (ja) |
| PT (1) | PT1814538E (ja) |
| SI (1) | SI1814538T1 (ja) |
| WO (1) | WO2006057769A2 (ja) |
| ZA (1) | ZA200704139B (ja) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6788460B2 (en) | 1998-04-15 | 2004-09-07 | Duke University | Projection screen apparatus |
| US6829087B2 (en) | 1998-04-15 | 2004-12-07 | Bright View Technologies, Inc. | Micro-lens array based light transmitting screen with tunable gain |
| US6816306B2 (en) | 1998-04-15 | 2004-11-09 | Bright View Technologies Inc. | Micro-lens array based light transmitting screen with high resolution and low imaging artifacts |
| US7977376B2 (en) * | 2001-06-27 | 2011-07-12 | Novartis Ag | Olopatadine formulations for topical nasal administration |
| ES2781090T3 (es) | 2007-02-07 | 2020-08-28 | Novartis Ag | Formulaciones de olopatadina para administración nasal tópica |
| US20110011392A1 (en) * | 2009-07-17 | 2011-01-20 | Wall G Michael | Olopatadine nasal spray regimen for children |
| WO2011027322A1 (en) | 2009-09-03 | 2011-03-10 | Ranbaxy Laboratories Limited | Extended release dosage form containing olopatadine for oral administration |
| GB2485604A (en) * | 2010-11-22 | 2012-05-23 | Martin Chard | Device for marking a surface |
| US9370483B2 (en) | 2013-09-13 | 2016-06-21 | Glenmark Specialty S.A. | Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine |
| EP3718533A1 (en) | 2013-09-13 | 2020-10-07 | Glenmark Specialty S.A. | Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine |
| US9937189B2 (en) * | 2013-09-13 | 2018-04-10 | Glenmark Specialty S.A. | Stable fixed dose pharmaceutical composition comprising mometasone and olopatadine |
| EP4272839A3 (en) | 2013-10-04 | 2024-01-03 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10016443B2 (en) | 2013-10-04 | 2018-07-10 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10548907B2 (en) | 2013-10-04 | 2020-02-04 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10653661B2 (en) | 2013-10-04 | 2020-05-19 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| US10758550B2 (en) | 2013-10-04 | 2020-09-01 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| CN104063850B (zh) * | 2014-06-24 | 2017-02-01 | 广东互维科技有限公司 | 红眼修复方法 |
| US11679210B2 (en) | 2014-10-03 | 2023-06-20 | Glenmark Specialty S.A. | Dispensing device and pharmaceutical composition for the treatment of rhinitis |
| CN107569454B (zh) * | 2017-09-29 | 2018-05-04 | 深圳大佛药业股份有限公司 | 一种盐酸奥洛他定鼻喷雾剂及其制备方法 |
| US11890409B1 (en) * | 2019-11-19 | 2024-02-06 | Saeed Rezakhany | Methods of curing early stages of, and preventing, upper respiratory infections and applicators therefor |
| USD969992S1 (en) * | 2020-12-23 | 2022-11-15 | Aptar France Sas | Device for nasal spray |
| WO2023167909A2 (en) * | 2022-03-02 | 2023-09-07 | Vijay Duggal | A hydrogen peroxide-based therapeutic spray for protection and treatment of mucosa |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE555319A (ja) * | 1956-03-21 | 1900-01-01 | ||
| US4923892A (en) * | 1985-08-17 | 1990-05-08 | Burroughs Wellcome Co. | Tricyclic aromatic compounds |
| GB8520662D0 (en) * | 1985-08-17 | 1985-09-25 | Wellcome Found | Tricyclic aromatic compounds |
| JPS6310784A (ja) * | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | 抗アレルギー剤 |
| GB2208646B (en) * | 1987-08-13 | 1991-06-26 | Glaxo Group Ltd | Indole derivatives |
| JPH0323237U (ja) * | 1989-07-19 | 1991-03-11 | ||
| US5641805A (en) * | 1995-06-06 | 1997-06-24 | Alcon Laboratories, Inc. | Topical ophthalmic formulations for treating allergic eye diseases |
| US5976573A (en) * | 1996-07-03 | 1999-11-02 | Rorer Pharmaceutical Products Inc. | Aqueous-based pharmaceutical composition |
| FR2803612B1 (fr) * | 2000-01-12 | 2002-12-06 | Michel Jean Louis Mar Doustaly | Point d'eau sanitaire adaptable a une cuvette de wc |
| GB0014892D0 (en) * | 2000-06-16 | 2000-08-09 | Glaxo Group Ltd | Novel pharmaceutical formulation |
| IT1317998B1 (it) * | 2000-06-26 | 2003-07-21 | Medical Internat Licensing N V | Valvola erogatrice per spray nasale. |
| TWI231759B (en) * | 2001-06-27 | 2005-05-01 | Alcon Inc | Olopatadine formulations for topical administration |
| JPWO2003024484A1 (ja) * | 2001-09-14 | 2004-12-24 | 小野薬品工業株式会社 | 掻痒症治療剤 |
| KR20050074577A (ko) * | 2002-11-12 | 2005-07-18 | 알콘, 인코퍼레이티드 | 알레르기성 비염을 치료하기 위한 항알레르기제 및스테로이드의 용도 |
| WO2004084859A2 (en) * | 2003-03-21 | 2004-10-07 | Nastech Pharmaceutical Company Inc. | Nasal calcitonin formulations containing chlorobutanol |
-
2005
- 2005-10-31 PL PL05820776T patent/PL1814538T3/pl unknown
- 2005-10-31 US US11/263,240 patent/US20060110328A1/en not_active Abandoned
- 2005-10-31 KR KR1020077014446A patent/KR101158603B1/ko active IP Right Grant
- 2005-10-31 EP EP05820776A patent/EP1814538B1/en active Active
- 2005-10-31 ES ES05820776T patent/ES2331619T3/es active Active
- 2005-10-31 CN CNA2005800402263A patent/CN101065122A/zh active Pending
- 2005-10-31 CA CA2586553A patent/CA2586553C/en active Active
- 2005-10-31 BR BRPI0518283-2A patent/BRPI0518283A2/pt not_active Application Discontinuation
- 2005-10-31 DK DK05820776T patent/DK1814538T3/da active
- 2005-10-31 ZA ZA200704139A patent/ZA200704139B/xx unknown
- 2005-10-31 MX MX2007005845A patent/MX2007005845A/es active IP Right Grant
- 2005-10-31 PT PT05820776T patent/PT1814538E/pt unknown
- 2005-10-31 DE DE602005016833T patent/DE602005016833D1/de active Active
- 2005-10-31 JP JP2007543080A patent/JP5068172B2/ja active Active
- 2005-10-31 CN CN201410053676.7A patent/CN103860540A/zh active Pending
- 2005-10-31 WO PCT/US2005/039268 patent/WO2006057769A2/en active Application Filing
- 2005-10-31 AT AT05820776T patent/ATE443516T1/de active
- 2005-10-31 SI SI200530855T patent/SI1814538T1/sl unknown
- 2005-10-31 AU AU2005309951A patent/AU2005309951B2/en active Active
-
2009
- 2009-11-03 CY CY20091101136T patent/CY1110528T1/el unknown
-
2013
- 2013-11-14 US US14/079,730 patent/US20140227326A1/en not_active Abandoned
-
2017
- 2017-03-03 US US15/448,834 patent/US20170172974A1/en not_active Abandoned
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