JP2008520589A - シロイノシトール誘導体を含む組成物およびタンパク質凝集障害を治療するための方法 - Google Patents

シロイノシトール誘導体を含む組成物およびタンパク質凝集障害を治療するための方法 Download PDF

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JP2008520589A
JP2008520589A JP2007541601A JP2007541601A JP2008520589A JP 2008520589 A JP2008520589 A JP 2008520589A JP 2007541601 A JP2007541601 A JP 2007541601A JP 2007541601 A JP2007541601 A JP 2007541601A JP 2008520589 A JP2008520589 A JP 2008520589A
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disease
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amyloid
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ジョアン マクローリン,
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
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  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2007541601A 2004-11-17 2005-11-17 シロイノシトール誘導体を含む組成物およびタンパク質凝集障害を治療するための方法 Pending JP2008520589A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62884004P 2004-11-17 2004-11-17
PCT/CA2005/001744 WO2006053428A1 (en) 2004-11-17 2005-11-17 Compositions comprising scyllo-inositol derivatives and methods to treat disorders of protein aggregation

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JP2012178707A Division JP2012214516A (ja) 2004-11-17 2012-08-10 シロイノシトール誘導体を含む組成物およびタンパク質凝集障害を治療するための方法

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JP2008520589A true JP2008520589A (ja) 2008-06-19
JP2008520589A5 JP2008520589A5 (https=) 2008-12-25

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JP2007541601A Pending JP2008520589A (ja) 2004-11-17 2005-11-17 シロイノシトール誘導体を含む組成物およびタンパク質凝集障害を治療するための方法
JP2012178707A Pending JP2012214516A (ja) 2004-11-17 2012-08-10 シロイノシトール誘導体を含む組成物およびタンパク質凝集障害を治療するための方法

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US (4) US20060189582A1 (https=)
EP (2) EP2186518A1 (https=)
JP (2) JP2008520589A (https=)
CN (2) CN103301094A (https=)
AU (1) AU2005306531B2 (https=)
BR (1) BRPI0517733A (https=)
CA (1) CA2588423A1 (https=)
MX (1) MX2007005870A (https=)
WO (1) WO2006053428A1 (https=)
ZA (1) ZA200704872B (https=)

Cited By (1)

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JP2012505162A (ja) * 2008-10-09 2012-03-01 ワラタ ファーマシューティカルズ, インコーポレイテッド 黄斑変性症関連障害を処置するためのscyllo−イノシトールの使用

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RU2432362C2 (ru) 2005-11-30 2011-10-27 Эбботт Лэборетриз Моноклональные антитела и их применения
EP1993523A4 (en) * 2006-02-17 2009-06-10 Joanne Mclaurin COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROTEIN AGGREGATION DISORDERS
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US20100173960A1 (en) * 2006-09-21 2010-07-08 Antonio Cruz The Combination of a Cyclohexanehexol and a NSAID for the Treatment of Neurodegenerative Diseases
US20100292157A1 (en) * 2006-11-24 2010-11-18 Antonio Cruz Combination Treatments for Alzheimer's Disease and Similar Diseases
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
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US20110105626A1 (en) * 2007-04-12 2011-05-05 Mclaurin Joanne Use of cyclohexanehexol derivatives for the treatment of polyglutamine diseases
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US9006283B2 (en) * 2007-07-12 2015-04-14 Acumen Pharmaceuticals, Inc. Methods of modifying amyloid β oligomers using non-peptidic compounds
US8962677B2 (en) * 2007-07-12 2015-02-24 Acumen Pharmaceuticals, Inc. Methods of restoring cognitive ability using non-peptidic compounds
JP2010538611A (ja) * 2007-09-07 2010-12-16 ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク タウタンパク質スクリーニングアッセイ
AT506535B1 (de) 2008-02-22 2010-04-15 Affiris Forschungs & Entwicklungs Gmbh Vaccine enthaltend alpha-synuclein-mimotope auf basis von peptiden
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JP2012505162A (ja) * 2008-10-09 2012-03-01 ワラタ ファーマシューティカルズ, インコーポレイテッド 黄斑変性症関連障害を処置するためのscyllo−イノシトールの使用

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AU2005306531A1 (en) 2006-05-26
ZA200704872B (en) 2008-12-31
US20110201694A1 (en) 2011-08-18
EP1824496A1 (en) 2007-08-29
WO2006053428A1 (en) 2006-05-26
US20090062403A1 (en) 2009-03-05
CA2588423A1 (en) 2006-05-26
EP1824496A4 (en) 2008-07-16
CN101102779A (zh) 2008-01-09
AU2005306531B2 (en) 2012-02-23
BRPI0517733A (pt) 2008-10-21
US20080306166A1 (en) 2008-12-11
EP2186518A1 (en) 2010-05-19
MX2007005870A (es) 2007-10-10
JP2012214516A (ja) 2012-11-08
CN103301094A (zh) 2013-09-18
US20060189582A1 (en) 2006-08-24

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