JP2008517917A5 - - Google Patents

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Publication number
JP2008517917A5
JP2008517917A5 JP2007538030A JP2007538030A JP2008517917A5 JP 2008517917 A5 JP2008517917 A5 JP 2008517917A5 JP 2007538030 A JP2007538030 A JP 2007538030A JP 2007538030 A JP2007538030 A JP 2007538030A JP 2008517917 A5 JP2008517917 A5 JP 2008517917A5
Authority
JP
Japan
Prior art keywords
igf
receptor
receptor ligand
ligand
therapeutic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007538030A
Other languages
English (en)
Japanese (ja)
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JP2008517917A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/037739 external-priority patent/WO2006047214A2/en
Publication of JP2008517917A publication Critical patent/JP2008517917A/ja
Publication of JP2008517917A5 publication Critical patent/JP2008517917A5/ja
Pending legal-status Critical Current

Links

JP2007538030A 2004-10-21 2005-10-21 癌を治療するための毒素および放射性核種結合ｉｇｆ−１受容体リガンド Pending JP2008517917A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62079404P 2004-10-21 2004-10-21
PCT/US2005/037739 WO2006047214A2 (en) 2004-10-21 2005-10-21 Toxins and radionuclides coupled to igf-1 receptor ligands for treatment of cancer

Publications (2)

Publication Number Publication Date
JP2008517917A JP2008517917A (ja) 2008-05-29
JP2008517917A5 true JP2008517917A5 (https=) 2008-12-11

Family

ID=36228252

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007538030A Pending JP2008517917A (ja) 2004-10-21 2005-10-21 癌を治療するための毒素および放射性核種結合ｉｇｆ−１受容体リガンド

Country Status (5)

Country Link
US (2) US8017102B2 (https=)
EP (1) EP1812082B1 (https=)
JP (1) JP2008517917A (https=)
CA (1) CA2582552A1 (https=)
WO (1) WO2006047214A2 (https=)

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WO2006047214A2 (en) * 2004-10-21 2006-05-04 Igf Oncology, Llc Toxins and radionuclides coupled to igf-1 receptor ligands for treatment of cancer
US7749966B2 (en) * 2006-12-21 2010-07-06 Boston Biomedical Research Institute Immunological modulation of insulin-like growth factor 1 for cancer prevention/treatment and prolonging longevity
CA2930681C (en) 2007-04-09 2019-10-15 The Board Of Trustees Of The University Of Arkansas Fusion protein of collagen-binding domain and parathyroid hormone
JP5264725B2 (ja) 2007-06-29 2013-08-14 第一三共株式会社 ペプチド性薬物の粘膜吸収促進剤を含有する粘膜投与用組成物、及びその投与方法
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EP2376099A4 (en) * 2008-12-19 2012-04-25 Univ Indiana Res & Tech Corp INSULIN AGAIN YL-BASED GROWTH FACTORS WITH HIGH ACTIVITY AT THE INSULIN RECEPTOR
AU2009335715B2 (en) 2008-12-19 2016-09-15 Indiana University Research And Technology Corporation Amide-based insulin prodrugs
EP2571992B1 (en) 2010-05-21 2018-04-25 Merrimack Pharmaceuticals, Inc. Bi-specific fusion proteins
JP5969469B2 (ja) 2010-06-16 2016-08-17 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションＩｎｄｉａｎａ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ インスリン受容体に対して高い活性を示す単鎖インスリンアゴニスト
EP2585102B1 (en) 2010-06-24 2015-05-06 Indiana University Research and Technology Corporation Amide-based insulin prodrugs
US9579273B2 (en) 2011-12-14 2017-02-28 The Kitasato Institute Delivery of therapeutic agents by a collagen binding protein
BR112014015156A2 (pt) 2011-12-20 2020-10-27 Indiana University Research And Technology Corporation análogos de insulina à base de ctp, seus métodos de produção e uso no tratamento de hiperglicemia, bem como sequência de ácido nucleico e célula hospedeira
EP3395358B1 (en) 2012-09-26 2019-11-06 Indiana University Research and Technology Corporation Insulin analog dimers
JP6538645B2 (ja) 2013-03-14 2019-07-03 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションＩｎｄｉａｎａ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ インスリン‐インクレチン複合物
CA2936675C (en) 2014-01-12 2023-06-27 Igf Oncology, Llc Fusion proteins containing insulin-like growth factor-1 and epidermal growth factor and variants thereof and uses thereof
US9737556B2 (en) 2014-06-13 2017-08-22 Trustees Of Tufts College FAP-activated therapeutic agents, and uses related thereto
CN106573073B (zh) 2014-06-13 2021-09-28 塔夫茨大学信托人 Fap激活的治疗剂以及其相关用途
CN108271356A (zh) 2014-09-24 2018-07-10 印第安纳大学研究及科技有限公司 肠降血糖素-胰岛素缀合物
JP6701208B2 (ja) 2014-09-24 2020-05-27 インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション 脂質化アミド系インスリンプロドラッグ
CN108367048B (zh) 2015-10-02 2022-08-12 银溪制药股份有限公司 用于组织修复的双特异性治疗性蛋白质
EP3595699A4 (en) * 2017-03-16 2020-12-23 Blaze Bioscience, Inc. PEPTIDIC CONJUGATES OF CARTILAGE ECOTROPISM AND THEIR METHODS OF USE
CN117442747A (zh) 2017-05-21 2024-01-26 Igf肿瘤公司 胰岛素样生长因子——用于治疗骨髓增生异常综合症的化学治疗缀合物
US12403179B2 (en) 2021-02-18 2025-09-02 The Board Of Trustees Of The University Of Arkansas Release of growth factors at wound healing stages

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WO2006047214A2 (en) * 2004-10-21 2006-05-04 Igf Oncology, Llc Toxins and radionuclides coupled to igf-1 receptor ligands for treatment of cancer

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