JP2008517871A5 - - Google Patents
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- Publication number
- JP2008517871A5 JP2008517871A5 JP2007515393A JP2007515393A JP2008517871A5 JP 2008517871 A5 JP2008517871 A5 JP 2008517871A5 JP 2007515393 A JP2007515393 A JP 2007515393A JP 2007515393 A JP2007515393 A JP 2007515393A JP 2008517871 A5 JP2008517871 A5 JP 2008517871A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- balsalazide
- administered
- cancer
- radiation therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 33
- 238000001959 radiotherapy Methods 0.000 claims 26
- IPOKCKJONYRRHP-FMQUCBEESA-N balsalazide Chemical compound C1=CC(C(=O)NCCC(=O)O)=CC=C1\N=N\C1=CC=C(O)C(C(O)=O)=C1 IPOKCKJONYRRHP-FMQUCBEESA-N 0.000 claims 21
- 229960004168 balsalazide Drugs 0.000 claims 21
- 206010028980 Neoplasm Diseases 0.000 claims 11
- 238000001356 surgical procedure Methods 0.000 claims 9
- 201000011510 cancer Diseases 0.000 claims 8
- 238000002512 chemotherapy Methods 0.000 claims 8
- 230000005855 radiation Effects 0.000 claims 7
- 230000036210 malignancy Effects 0.000 claims 6
- 208000004232 Enteritis Diseases 0.000 claims 4
- 206010061424 Anal cancer Diseases 0.000 claims 2
- 208000007860 Anus Neoplasms Diseases 0.000 claims 2
- 206010005003 Bladder cancer Diseases 0.000 claims 2
- 206010008342 Cervix carcinoma Diseases 0.000 claims 2
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 2
- 208000032271 Malignant tumor of penis Diseases 0.000 claims 2
- 206010033128 Ovarian cancer Diseases 0.000 claims 2
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 2
- 208000002471 Penile Neoplasms Diseases 0.000 claims 2
- 206010034299 Penile cancer Diseases 0.000 claims 2
- 206010060862 Prostate cancer Diseases 0.000 claims 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 2
- 208000024313 Testicular Neoplasms Diseases 0.000 claims 2
- 206010057644 Testis cancer Diseases 0.000 claims 2
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 2
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 2
- 201000011165 anus cancer Diseases 0.000 claims 2
- 210000000988 bone and bone Anatomy 0.000 claims 2
- 201000010881 cervical cancer Diseases 0.000 claims 2
- 230000002496 gastric effect Effects 0.000 claims 2
- 230000002163 immunogen Effects 0.000 claims 2
- 201000002314 small intestine cancer Diseases 0.000 claims 2
- 201000003120 testicular cancer Diseases 0.000 claims 2
- 201000005112 urinary bladder cancer Diseases 0.000 claims 2
- 206010014733 Endometrial cancer Diseases 0.000 claims 1
- 206010014759 Endometrial neoplasm Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 230000000112 colonic effect Effects 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 210000004696 endometrium Anatomy 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 210000004877 mucosa Anatomy 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 206010046885 vaginal cancer Diseases 0.000 claims 1
- 208000013139 vaginal neoplasm Diseases 0.000 claims 1
- 210000003905 vulva Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60895104P | 2004-05-28 | 2004-05-28 | |
| US60/608,951 | 2004-10-26 | ||
| PCT/US2005/018757 WO2005117851A1 (en) | 2004-05-28 | 2005-05-27 | Prevention, treatment, and amelioration of radiation induced enteritis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011233631A Division JP2012021031A (ja) | 2004-10-26 | 2011-10-25 | 放射線誘発性腸炎の予防、処置、および回復 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008517871A JP2008517871A (ja) | 2008-05-29 |
| JP2008517871A5 true JP2008517871A5 (enExample) | 2008-07-10 |
| JP5009152B2 JP5009152B2 (ja) | 2012-08-22 |
Family
ID=40096437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007515393A Expired - Fee Related JP5009152B2 (ja) | 2004-05-28 | 2005-05-27 | 放射線誘発性腸炎の予防、処置、および回復 |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US20080306029A1 (enExample) |
| JP (1) | JP5009152B2 (enExample) |
| KR (1) | KR20130028807A (enExample) |
| DE (1) | DE602005022175D1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012021031A (ja) * | 2004-10-26 | 2012-02-02 | Salix Pharmaceuticals Inc | 放射線誘発性腸炎の予防、処置、および回復 |
| RU2618452C1 (ru) * | 2015-12-28 | 2017-05-03 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Астраханский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО Астраханский ГМУ Минздрава России) | Способ прогнозирования энтерита |
| CA3259788A1 (en) * | 2022-06-22 | 2023-12-28 | Marjan BOERMA | METHOD FOR ATTENUATING INJURY BY RADIATION USING GERANYL TRANSFERASE INHIBITORS |
| CN115252685A (zh) * | 2022-06-24 | 2022-11-01 | 内蒙古民族大学附属医院 | 一种蒙药巴特日-7在预防和治疗放射性肠道损伤中的应用 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE791889A (fr) * | 1971-11-26 | 1973-05-24 | Pharmacia Ab | Nouveaux derives de la pyridine |
| US4298595A (en) * | 1978-12-20 | 1981-11-03 | Dynapol | Pharmaceutical preparations containing a polymeric agent for releasing 5-aminosalicylic acid or its salts into the gastrointestinal tract |
| US4960765A (en) * | 1980-03-20 | 1990-10-02 | Farmaceutisk Laboratorium Ferring A/S | Pharmaceutical composition and method for the treatment of colitis ulcerosa and Crohn's disease by oral administration |
| WO1981002671A1 (en) * | 1980-03-20 | 1981-10-01 | Ferring Farma Lab | Pharmaceutical composition and method for the treatment of colitis ulcerosa and crohn's disease by oral administration |
| EP0039306B1 (de) * | 1980-03-28 | 1984-01-11 | Ciba-Geigy Ag | Neue Azofarbstoffe, Verfahren zu deren Herstellung und deren Verwendung |
| US4412922A (en) * | 1980-07-02 | 1983-11-01 | Abcor, Inc. | Positive-charged ultrafiltration membrane for the separation of cathodic/electrodeposition-paint compositions |
| US4412992A (en) * | 1980-07-21 | 1983-11-01 | Biorex Laboratories Limited | 2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith |
| ZA825384B (en) * | 1981-07-31 | 1983-05-25 | Tillott J B Ltd | Orally administrable pharmaceutical compositions |
| US4562024A (en) * | 1982-07-06 | 1985-12-31 | Sterling Drug Inc. | Process for preparing granulate containing poorly compressible medicinally active matter |
| SE8405924L (sv) * | 1984-11-23 | 1986-05-24 | Pharmacia Ab | Nya azoforeningar |
| US4781925A (en) * | 1986-03-06 | 1988-11-01 | American Home Products Corporation | Calcium supplement compressed tablets |
| US5374430A (en) * | 1986-09-18 | 1994-12-20 | London School Of Pharmacy | Pharmaceutical formulation |
| EP0439453B1 (en) * | 1987-10-12 | 1994-01-19 | Exomed Australia Pty. Ltd. (ACN 051 976 446) | Improved method for treatment of gastrointestinal disorders |
| US5064637A (en) * | 1989-05-30 | 1991-11-12 | Board Of Regents, The University Of Texas System | Substituted sulfonamide derivatives which inhibit allergic reactions |
| US5095073A (en) * | 1990-03-02 | 1992-03-10 | Exxon Research And Engineering Company | Water soluble rigid rod sulfonated aromatic polyamide |
| US5519014A (en) * | 1990-10-22 | 1996-05-21 | Borody; Thomas J. | Treatment of non-inflammatory and non-infectious bowel disorders |
| ES2111659T3 (es) * | 1992-03-11 | 1998-03-16 | Asta Medica Ag | Comprimidos, granulados y nodulos con alto contenido en sustancias activas para formas de administracion solidas de alta concentracion. |
| US5498608A (en) * | 1994-01-07 | 1996-03-12 | Salix Pharmaceuticals | Use of 2-hydroxy-5-phenylazobenzoic acid derivatives as colon cancer chemopreventative and chemotherapeutic agents |
| US6562629B1 (en) * | 1999-08-11 | 2003-05-13 | Cedars-Sinai Medical Center | Method of diagnosing irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth by detecting the presence of anti-saccharomyces cerivisiae antibodies (asca) in human serum |
| US6231888B1 (en) * | 1996-01-18 | 2001-05-15 | Perio Products Ltd. | Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps |
| SE9700934D0 (sv) * | 1997-03-14 | 1997-03-14 | Astra Ab | New formulation |
| DE69839261T2 (de) * | 1997-04-01 | 2009-03-26 | Borody, Thomas Julius, Five Dock | Verfahren und zusammensetzungen zur behandlung entzündlicher darmerkrankungen |
| US6551632B2 (en) * | 1997-04-01 | 2003-04-22 | Thomas Julius Borody | Methods and compositions for treating inflammatory bowel disease |
| US20030078205A1 (en) * | 2001-07-31 | 2003-04-24 | Podolsky Daniel K. | Methods and compositions for treating and preventing distal bowel lesions |
| AUPO665397A0 (en) * | 1997-05-07 | 1997-05-29 | Borody, Thomas Julius | Novel therapy for constipation |
| US6144381A (en) * | 1997-05-14 | 2000-11-07 | International Business Machines Corporation | Systems, methods and computer program products for compass navigation of avatars in three dimensional worlds |
| DE19732903A1 (de) * | 1997-07-30 | 1999-02-04 | Falk Pharma Gmbh | Pellet-Formulierung zur Behandlung des Intestinaltraktes |
| US5927500A (en) * | 1998-06-09 | 1999-07-27 | Milliken & Company | Pharmaceutical containment package |
| AUPP437698A0 (en) * | 1998-06-30 | 1998-07-23 | Baumgart, Karl | Methods for treatment of coronary, carotid and other vascular disease |
| US6517871B1 (en) * | 1998-07-20 | 2003-02-11 | Smithkline Beecham Corporation | Bioenhanced formulations comprising eprosartan in oral solid dosage form |
| US6326364B1 (en) * | 1999-02-08 | 2001-12-04 | Cedars-Sinai Medical Center | Use of 5-aminosalicylates as antimicrobial agents |
| US20030138399A1 (en) * | 1999-05-14 | 2003-07-24 | Anton Peter A. | Anti-inflammatory therapy for inflammatory mediated infection |
| DE60115465T2 (de) * | 2000-08-29 | 2006-08-03 | Nobex Corp. | Immunoregulierende verbindungen, deren derivate und ihre verwendung |
| EP1313699B1 (en) * | 2000-08-29 | 2010-03-10 | Biocon Limited | 5-asa derivatives having anti-inflammatory and antibiotic activity and methods of treating diseases therewith |
| US6562871B1 (en) * | 2000-11-06 | 2003-05-13 | Boehringer Ingelheim Pharmaceuticals, Inc. | Dry granulation of pharmaceutical formulation comprising mexiletine |
| CA2359812C (en) * | 2000-11-20 | 2004-02-10 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures |
| US6407128B1 (en) * | 2001-12-03 | 2002-06-18 | Elan Pharmaceuticals, Inc. | Method for increasing the bioavailability of metaxalone |
| AU2003226752A1 (en) * | 2002-03-28 | 2003-10-13 | Synthon B.V. | Venlafaxine base |
| JPWO2004082715A1 (ja) * | 2003-03-20 | 2006-06-22 | エーザイ株式会社 | 炎症性腸疾患治療剤としての併用医薬 |
| US7825106B2 (en) * | 2003-09-03 | 2010-11-02 | Agi Therapeutics Ltd. | Modified release formulations and methods of treating inflammatory bowel disease |
| US7737133B2 (en) * | 2003-09-03 | 2010-06-15 | Agi Therapeutics Ltd. | Formulations and methods of treating inflammatory bowel disease |
| US7452872B2 (en) * | 2005-08-24 | 2008-11-18 | Salix Pharmaceuticals, Inc. | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives |
| EP2529729A1 (en) * | 2005-08-24 | 2012-12-05 | Salix Pharmaceuticals, Inc. | Balsalazide formulations and manufacture thereof |
| US20100048519A1 (en) * | 2006-09-13 | 2010-02-25 | Chyon-Hwa Yeh | Methods of treatment for ulcerative colitis using aminosalicylate |
-
2005
- 2005-05-27 KR KR1020137005518A patent/KR20130028807A/ko not_active Ceased
- 2005-05-27 DE DE602005022175T patent/DE602005022175D1/de not_active Expired - Lifetime
- 2005-05-27 US US10/588,254 patent/US20080306029A1/en not_active Abandoned
- 2005-05-27 JP JP2007515393A patent/JP5009152B2/ja not_active Expired - Fee Related
-
2015
- 2015-06-05 US US14/731,692 patent/US20160120886A1/en not_active Abandoned
-
2017
- 2017-08-10 US US15/673,578 patent/US20170333458A1/en not_active Abandoned
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