ATE499378T1 - Anthracyclinderivate - Google Patents

Anthracyclinderivate

Info

Publication number
ATE499378T1
ATE499378T1 AT05733719T AT05733719T ATE499378T1 AT E499378 T1 ATE499378 T1 AT E499378T1 AT 05733719 T AT05733719 T AT 05733719T AT 05733719 T AT05733719 T AT 05733719T AT E499378 T1 ATE499378 T1 AT E499378T1
Authority
AT
Austria
Prior art keywords
diagnosis
anthracycline derivatives
radiolabelled
derivatives
delivery system
Prior art date
Application number
AT05733719T
Other languages
English (en)
Inventor
Katarin Edwards
Stefan Sjoeberg
Joergen Carlsson
Lars Gedda
Original Assignee
Nuclisome Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuclisome Ab filed Critical Nuclisome Ab
Application granted granted Critical
Publication of ATE499378T1 publication Critical patent/ATE499378T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT05733719T 2004-04-22 2005-04-22 Anthracyclinderivate ATE499378T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0401066A SE0401066D0 (sv) 2004-04-22 2004-04-22 Chemical Derivatives
PCT/SE2005/000596 WO2005103065A1 (en) 2004-04-22 2005-04-22 Anthracycline derivatives

Publications (1)

Publication Number Publication Date
ATE499378T1 true ATE499378T1 (de) 2011-03-15

Family

ID=32322666

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05733719T ATE499378T1 (de) 2004-04-22 2005-04-22 Anthracyclinderivate

Country Status (10)

Country Link
US (2) US20070258890A1 (de)
EP (1) EP1740599B1 (de)
JP (1) JP5156372B2 (de)
CN (1) CN1956992A (de)
AT (1) ATE499378T1 (de)
BR (1) BRPI0510062A (de)
DE (1) DE602005026510D1 (de)
ES (1) ES2360708T3 (de)
SE (1) SE0401066D0 (de)
WO (1) WO2005103065A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013523726A (ja) * 2010-04-01 2013-06-17 オンコレナ エービー 腎細胞癌の改良された治療
CN102086219A (zh) * 2010-11-24 2011-06-08 河南师范大学 具有抗癌活性的蒽环类抗生素简单结构类似物及制备方法
CN102146107B (zh) * 2011-01-14 2014-12-31 河南师范大学 (s)-2-羟烷基-1,4-二羟基-9,10-蒽醌与糖基缀合物的合成及抗肿瘤活性
CN113750047A (zh) * 2020-05-28 2021-12-07 浙江大学 多功能纳米脂质体、制备方法及应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS539756A (en) * 1976-07-14 1978-01-28 Microbial Chem Res Found Antitumers
US4250303A (en) * 1977-10-17 1981-02-10 Sri International N-Benzyl anthracyclines
GB2007645B (en) * 1977-10-17 1982-05-12 Stanford Res Inst Int Benzyl anthracyclines and pharmaceutical compositions containing them
US4177264A (en) * 1977-10-17 1979-12-04 Sri International N-benzyl anthracyclines
CA1248944A (en) * 1982-09-28 1989-01-17 Gareth J. Thomas Anthracycline glycosides
US4610977A (en) * 1985-04-08 1986-09-09 The University Of Tennessee Research Corporation N-alkyl and N-benzyl adriamycin derivatives
DE3641833A1 (de) * 1986-12-08 1988-06-09 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
EP0308977B1 (de) * 1987-09-25 1993-12-08 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Anthracyclin-Derivate mit Inhibitorwirkung gegen die reverse Transkriptase des menschlichen Immundefizienzvirus
EP0971716A1 (de) * 1996-03-22 2000-01-19 Waldemar Priebe Bis-anthracycline mit hoher wirksamkeit gegen doxorubicin resistente tumore
AU778910B2 (en) * 1999-03-19 2004-12-23 Houston Pharmaceuticals, Inc. Methods and compositions for the manufacture of C-3' and C-4' anthracycline antibiotics
AU2002358298A1 (en) * 2001-12-27 2003-07-24 Albany Molecular Research, Inc. Methods for preparing doxorubicin derivatives

Also Published As

Publication number Publication date
BRPI0510062A (pt) 2007-10-16
CN1956992A (zh) 2007-05-02
ES2360708T3 (es) 2011-06-08
JP2007533736A (ja) 2007-11-22
US8609135B2 (en) 2013-12-17
SE0401066D0 (sv) 2004-04-22
WO2005103065A1 (en) 2005-11-03
US20100092388A1 (en) 2010-04-15
EP1740599A1 (de) 2007-01-10
DE602005026510D1 (en) 2011-04-07
EP1740599B1 (de) 2011-02-23
JP5156372B2 (ja) 2013-03-06
US20070258890A1 (en) 2007-11-08

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Legal Events

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