JP2008511541A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008511541A5 JP2008511541A5 JP2007511111A JP2007511111A JP2008511541A5 JP 2008511541 A5 JP2008511541 A5 JP 2008511541A5 JP 2007511111 A JP2007511111 A JP 2007511111A JP 2007511111 A JP2007511111 A JP 2007511111A JP 2008511541 A5 JP2008511541 A5 JP 2008511541A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- aryl
- administered
- halogen
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 claims 55
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 36
- 125000000217 alkyl group Chemical group 0.000 claims 32
- 125000003118 aryl group Chemical group 0.000 claims 24
- 125000005843 halogen group Chemical group 0.000 claims 24
- -1 prostaglandin compound Chemical class 0.000 claims 18
- 125000004104 aryloxy group Chemical group 0.000 claims 16
- 125000000000 cycloalkoxy group Chemical group 0.000 claims 16
- 125000000753 cycloalkyl group Chemical group 0.000 claims 16
- 229910052736 halogen Inorganic materials 0.000 claims 16
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 16
- 125000004043 oxo group Chemical group O=* 0.000 claims 16
- 229920006395 saturated elastomer Polymers 0.000 claims 16
- 208000018522 Gastrointestinal disease Diseases 0.000 claims 10
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 10
- 239000004215 Carbon black (E152) Substances 0.000 claims 8
- 125000004423 acyloxy group Chemical group 0.000 claims 8
- 125000003545 alkoxy group Chemical group 0.000 claims 8
- 150000002367 halogens Chemical group 0.000 claims 8
- 229930195733 hydrocarbon Natural products 0.000 claims 8
- 150000002430 hydrocarbons Chemical class 0.000 claims 8
- 125000001183 hydrocarbyl group Chemical group 0.000 claims 8
- 229910052739 hydrogen Inorganic materials 0.000 claims 8
- 239000001257 hydrogen Substances 0.000 claims 8
- 239000000546 pharmaceutical excipient Substances 0.000 claims 6
- 208000010643 digestive system disease Diseases 0.000 claims 4
- 208000018685 gastrointestinal system disease Diseases 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 239000002904 solvent Substances 0.000 claims 4
- 238000011282 treatment Methods 0.000 claims 4
- 206010010774 Constipation Diseases 0.000 claims 2
- 201000006549 dyspepsia Diseases 0.000 claims 2
- 125000001153 fluoro group Chemical group F* 0.000 claims 2
- 208000002551 irritable bowel syndrome Diseases 0.000 claims 2
- 238000011866 long-term treatment Methods 0.000 claims 2
- 150000004667 medium chain fatty acids Chemical group 0.000 claims 2
- 125000002950 monocyclic group Chemical group 0.000 claims 2
- 0 CC(C(**)C(CC1)C2OC1(*)C(*)(*)*)C2*=C Chemical compound CC(C(**)C(CC1)C2OC1(*)C(*)(*)*)C2*=C 0.000 description 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60652104P | 2004-09-02 | 2004-09-02 | |
| US66631705P | 2005-03-30 | 2005-03-30 | |
| US66659305P | 2005-03-31 | 2005-03-31 | |
| PCT/JP2005/016464 WO2006025599A1 (en) | 2004-09-02 | 2005-09-01 | Prostaglandin derivatives for treating gastrointestinal disorder |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012232180A Division JP2013049688A (ja) | 2004-09-02 | 2012-10-19 | 胃腸障害処置用プロスタグランジン誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008511541A JP2008511541A (ja) | 2008-04-17 |
| JP2008511541A5 true JP2008511541A5 (https=) | 2008-10-16 |
Family
ID=35229739
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007511111A Withdrawn JP2008511541A (ja) | 2004-09-02 | 2005-09-01 | 胃腸障害処置用プロスタグランジン誘導体 |
| JP2012232180A Withdrawn JP2013049688A (ja) | 2004-09-02 | 2012-10-19 | 胃腸障害処置用プロスタグランジン誘導体 |
| JP2015102184A Expired - Lifetime JP6408426B2 (ja) | 2004-09-02 | 2015-05-19 | 胃腸障害処置用プロスタグランジン誘導体 |
| JP2018102339A Withdrawn JP2018150354A (ja) | 2004-09-02 | 2018-05-29 | 胃腸障害処置用プロスタグランジン誘導体 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012232180A Withdrawn JP2013049688A (ja) | 2004-09-02 | 2012-10-19 | 胃腸障害処置用プロスタグランジン誘導体 |
| JP2015102184A Expired - Lifetime JP6408426B2 (ja) | 2004-09-02 | 2015-05-19 | 胃腸障害処置用プロスタグランジン誘導体 |
| JP2018102339A Withdrawn JP2018150354A (ja) | 2004-09-02 | 2018-05-29 | 胃腸障害処置用プロスタグランジン誘導体 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8748481B2 (https=) |
| EP (1) | EP1791545B1 (https=) |
| JP (4) | JP2008511541A (https=) |
| KR (4) | KR20180033310A (https=) |
| CN (1) | CN102885821A (https=) |
| AR (1) | AR050626A1 (https=) |
| AU (1) | AU2005278323B2 (https=) |
| BR (1) | BRPI0514891A (https=) |
| CA (1) | CA2577284A1 (https=) |
| ES (1) | ES2603381T3 (https=) |
| IL (1) | IL181332A (https=) |
| MX (1) | MX2007002602A (https=) |
| NO (1) | NO340989B1 (https=) |
| NZ (1) | NZ553434A (https=) |
| TW (1) | TWI387454B (https=) |
| WO (1) | WO2006025599A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1562604T3 (da) * | 2002-10-23 | 2012-04-02 | Sucampo Ag | Prostaglandinforbindelser til behandling af fedme |
| ATE489096T1 (de) * | 2003-07-03 | 2010-12-15 | Sucampo Ag | Pharmazeutische magensaftresistent überzogene zusammensetzung enthaltend prostaglandin-analoga als chloridkanalöffner |
| EP1984027B1 (en) * | 2006-01-24 | 2015-12-30 | R-Tech Ueno, Ltd. | Pharmaceutical composition comprising a bi-cyclic compound and method for stabilizing the bi-cyclic compound |
| US20090030072A1 (en) * | 2007-07-03 | 2009-01-29 | Sucampo Ag | Pharmaceutical combination of opioid and prostaglandin compound |
| JP2015514681A (ja) * | 2012-04-23 | 2015-05-21 | スキャンポ・アーゲーＳｕｃａｍｐｏ ＡＧ | 下痢を伴う過敏性腸症候群の処置方法 |
| MY176162A (en) * | 2013-02-04 | 2020-07-24 | Taisho Pharmaceutical Co Ltd | Prophylactic or therapeutic drug for constipation |
| WO2014159679A1 (en) | 2013-03-12 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for using lubiprostone to absorb fluid from the subretinal space |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428062A (en) | 1987-01-28 | 1995-06-27 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti ulcers containing same |
| US5225439A (en) | 1987-01-28 | 1993-07-06 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti ulcers containing same |
| US5166174A (en) | 1987-01-28 | 1992-11-24 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti-ulcers containing same |
| US5317032A (en) * | 1987-10-02 | 1994-05-31 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Prostaglandin cathartic |
| RU2695274C3 (ru) | 1999-10-15 | 2020-11-09 | Сукампо Аг | Новые композиции и способы их стабилизации |
| US6414016B1 (en) | 2000-09-05 | 2002-07-02 | Sucampo, A.G. | Anti-constipation composition |
| TWI302100B (en) * | 2001-05-02 | 2008-10-21 | Sucampo Ag | Composition for treating drug-induced constipation |
| WO2002094274A1 (en) | 2001-05-18 | 2002-11-28 | Sucampo Ag | Cathartic composition |
| EP1420794B1 (en) * | 2001-08-31 | 2017-12-27 | Sucampo AG | Prostaglandin analogs as chloride channel openers |
| AR037524A1 (es) * | 2001-11-14 | 2004-11-17 | Sucampo Ag | Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion |
| TWI263505B (en) | 2001-11-19 | 2006-10-11 | Sucampo Ag | Pharmaceutical composition comprising a C1C-2 channel opener |
| BRPI0317740B8 (pt) * | 2002-12-27 | 2021-05-25 | Sucampo Ag | uso do composto 13,14-diidro-15-ceto-16,16-diflúorprostaglandina e1 |
| ATE489096T1 (de) | 2003-07-03 | 2010-12-15 | Sucampo Ag | Pharmazeutische magensaftresistent überzogene zusammensetzung enthaltend prostaglandin-analoga als chloridkanalöffner |
-
2005
- 2005-08-31 TW TW094129818A patent/TWI387454B/zh not_active IP Right Cessation
- 2005-09-01 KR KR1020187008381A patent/KR20180033310A/ko not_active Ceased
- 2005-09-01 KR KR1020167036382A patent/KR20170003712A/ko not_active Ceased
- 2005-09-01 WO PCT/JP2005/016464 patent/WO2006025599A1/en not_active Ceased
- 2005-09-01 CA CA002577284A patent/CA2577284A1/en not_active Withdrawn
- 2005-09-01 JP JP2007511111A patent/JP2008511541A/ja not_active Withdrawn
- 2005-09-01 MX MX2007002602A patent/MX2007002602A/es active IP Right Grant
- 2005-09-01 ES ES05782157.1T patent/ES2603381T3/es not_active Expired - Lifetime
- 2005-09-01 AU AU2005278323A patent/AU2005278323B2/en not_active Expired
- 2005-09-01 BR BRPI0514891-0A patent/BRPI0514891A/pt not_active Application Discontinuation
- 2005-09-01 CN CN2012103704021A patent/CN102885821A/zh active Pending
- 2005-09-01 KR KR1020077004900A patent/KR20070048221A/ko not_active Ceased
- 2005-09-01 US US11/216,012 patent/US8748481B2/en not_active Expired - Lifetime
- 2005-09-01 KR KR1020137034994A patent/KR20140019006A/ko not_active Ceased
- 2005-09-01 EP EP05782157.1A patent/EP1791545B1/en not_active Expired - Lifetime
- 2005-09-01 NZ NZ553434A patent/NZ553434A/en not_active IP Right Cessation
- 2005-09-02 AR ARP050103687A patent/AR050626A1/es not_active Application Discontinuation
-
2007
- 2007-02-14 IL IL181332A patent/IL181332A/en not_active IP Right Cessation
- 2007-03-30 NO NO20071704A patent/NO340989B1/no not_active IP Right Cessation
-
2012
- 2012-10-19 JP JP2012232180A patent/JP2013049688A/ja not_active Withdrawn
-
2014
- 2014-04-30 US US14/265,801 patent/US20140315994A1/en not_active Abandoned
-
2015
- 2015-05-19 JP JP2015102184A patent/JP6408426B2/ja not_active Expired - Lifetime
-
2018
- 2018-05-29 JP JP2018102339A patent/JP2018150354A/ja not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TWI316942B (en) | Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents | |
| TWI852999B (zh) | 治療脂肪性肝病及/或脂肪性肝炎的方法 | |
| RU2003109622A (ru) | Композиция слабительного средства | |
| JP7624924B2 (ja) | ニトロキソリンプロドラッグ及びその使用 | |
| CN1242991C (zh) | 阿朴啡酯类及其治疗用途 | |
| CA2419741A1 (en) | Anti-constipation and cathartic composition comprising bi-cyclic 15-keto prostaglandin derivatives | |
| JP2012507522A5 (https=) | ||
| JPH0219805B2 (https=) | ||
| WO1998034916A1 (fr) | Derives de 11,15-o-dialkylprostaglandine e, leur procede de production, et medicaments renfermant ceux-ci comme principe actif | |
| JP2011502174A5 (https=) | ||
| JP2010505865A5 (https=) | ||
| KR20110051286A (ko) | 신규의 프로스타글란딘 ｉ2 유도체 | |
| WO2014129495A1 (ja) | 眼疾患処置薬 | |
| JP2008511541A5 (https=) | ||
| JP2006513232A5 (https=) | ||
| JP2004529960A5 (https=) | ||
| US9447020B2 (en) | Polyunsaturated fatty acid monoglycerides, derivatives, and uses thereof | |
| RU2011119533A (ru) | Композиции и способы для лечения нарушений деятельности, связанных с ренин-ангиотензин-альдостероновой системой (раас) | |
| JP2010502568A5 (https=) | ||
| JP2010502568A (ja) | 消化管の重炭酸分泌を促進するための方法および組成物 | |
| RU2440338C2 (ru) | Способ и композиция для лечения заболеваний центральной нервной системы | |
| EP0357403A2 (en) | Substituted beta-diketones | |
| JP2010533707A5 (https=) | ||
| JP2006506381A5 (https=) | ||
| WO2021256547A1 (ja) | ＳＡＲＳ－ＣｏＶ－２感染症の治療、予防または緩和用組成物 |