JP2008508188A5 - - Google Patents

Download PDF

Info

Publication number
JP2008508188A5
JP2008508188A5 JP2007504792A JP2007504792A JP2008508188A5 JP 2008508188 A5 JP2008508188 A5 JP 2008508188A5 JP 2007504792 A JP2007504792 A JP 2007504792A JP 2007504792 A JP2007504792 A JP 2007504792A JP 2008508188 A5 JP2008508188 A5 JP 2008508188A5
Authority
JP
Japan
Prior art keywords
thiazol
ethyl
phenyl
amino
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007504792A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008508188A (ja
JP4978464B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2005/014136 external-priority patent/WO2006011631A2/en
Publication of JP2008508188A publication Critical patent/JP2008508188A/ja
Publication of JP2008508188A5 publication Critical patent/JP2008508188A5/ja
Application granted granted Critical
Publication of JP4978464B2 publication Critical patent/JP4978464B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2007504792A 2004-07-27 2005-07-27 Ｖａｐ−１阻害剤活性を有するチアゾール誘導体 Expired - Fee Related JP4978464B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2004904196 2004-07-27
AU2004904196A AU2004904196A0 (en) 2004-07-27 Thiazole Derivatives Having VAP-1 Inhibitory Activity
PCT/JP2005/014136 WO2006011631A2 (en) 2004-07-27 2005-07-27 Thiazole derivatives having vap-1 inhibitory activity

Publications (3)

Publication Number Publication Date
JP2008508188A JP2008508188A (ja) 2008-03-21
JP2008508188A5 true JP2008508188A5 (https=) 2008-08-14
JP4978464B2 JP4978464B2 (ja) 2012-07-18

Family

ID=35734947

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007504792A Expired - Fee Related JP4978464B2 (ja) 2004-07-27 2005-07-27 Ｖａｐ−１阻害剤活性を有するチアゾール誘導体

Country Status (10)

Country Link
US (1) US20070254931A1 (https=)
EP (1) EP1786792B1 (https=)
JP (1) JP4978464B2 (https=)
KR (1) KR20070050932A (https=)
CN (1) CN101031555A (https=)
AT (1) ATE427941T1 (https=)
CA (1) CA2575411A1 (https=)
DE (1) DE602005013793D1 (https=)
ES (1) ES2324922T3 (https=)
WO (1) WO2006011631A2 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8748627B2 (en) 2006-02-15 2014-06-10 Abbvie Inc. Acetyl-CoA carboxylase (ACC) inhibitors and their use in diabetes, obesity and metabolic syndrome
CN101384568B (zh) * 2006-02-15 2012-12-12 雅培制药有限公司 乙酰辅酶a羧化酶(acc)抑制剂及其在糖尿病、肥胖症和代谢综合征中的应用
EP2599498A1 (en) 2007-06-25 2013-06-05 R-Tech Ueno, Ltd. Composition for ophthalmic disease associated with hypoxia or ischemia
US20100210697A1 (en) * 2007-10-19 2010-08-19 R-Tech Ueno, Ltd. Pharmaceutical composition for treatment of cataract
WO2009061830A1 (en) * 2007-11-06 2009-05-14 Massachusetts Eye & Ear Infirmary Methods and compositions for treating conditions associated with angiogenesis using a vascular adhesion protein-1 (vap-1) inhibitor
JP5480819B2 (ja) * 2008-01-18 2014-04-23 アラーガン インコーポレイテッド 選択的サブタイプアルファ２アドレナリンアゴニスト及びその使用方法
TWI437986B (zh) 2008-01-31 2014-05-21 R Tech Ueno Ltd 噻唑衍生物及使用該衍生物作為ｖａｐ－１抑制劑之用途
TWI490214B (zh) 2008-05-30 2015-07-01 艾德克 上野股份有限公司 苯或噻吩衍生物及該等作為ｖａｐ－１抑制劑之用途
NZ592603A (en) * 2008-10-21 2013-02-22 Metabolex Inc Aryl gpr120 receptor agonists and uses thereof
UA112154C2 (uk) 2009-09-08 2016-08-10 Біоті Терапіс Корп. Застосування повністю людського анти-vap-1-антитіла для лікування фіброзних станів
FI20115234A0 (fi) 2011-03-08 2011-03-08 Biotie Therapies Corp Uusia pyridatsinoni- ja pyridoniyhdisteitä
SG193307A1 (en) 2011-03-15 2013-10-30 Astellas Pharma Inc Guanidine compound
US8921576B2 (en) 2011-10-19 2014-12-30 Kowa Company, Ltd. Spiroindoline compound, and medicinal agent comprising same
WO2014199171A1 (en) 2013-06-12 2014-12-18 Proximagen Limited New therapeutic uses of enzyme inhibitors
EP3131539B1 (en) 2014-04-15 2018-12-05 Pécsi Tudományegyetem Semicarbazide-sensitive amine oxidase inhibitors for use as analgesics in traumatic neuropathy and neurogenic inflammation
WO2015189534A1 (en) 2014-06-12 2015-12-17 Proximagen Limited Vap-1 inhibitors for treating muscular dystrophy
CN104478828B (zh) * 2014-12-10 2016-07-06 漳州片仔癀药业股份有限公司 2-氨基-7-取代苯并噻唑类化合物及其制备方法与用途
JO3546B1 (ar) * 2015-01-09 2020-07-05 Kyowa Kirin Co Ltd طريقة لإنتاج مشتق ثيازول
JP2018076236A (ja) 2015-06-05 2018-05-17 株式会社アールテック・ウエノ がんを処置するための医薬組成物
US10759781B2 (en) 2015-08-06 2020-09-01 Ube Industries, Ltd. Substituted guanidine derivatives
HK1256174A1 (zh) 2015-12-07 2019-09-13 Benevolentai Cambridge Limited 用於治疗疼痛的 vap-1 抑制剂
ES2844926T3 (es) * 2016-05-12 2021-07-23 Boehringer Ingelheim Int Derivados de piridinilo, composiciones farmacéuticas y usos de los mismos como inhibidores de AOC3
CN110114350B (zh) 2016-12-28 2022-03-04 宇部兴产株式会社 取代胍化合物
US10213306B2 (en) 2017-03-31 2019-02-26 Neochord, Inc. Minimally invasive heart valve repair in a beating heart

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3264595D1 (en) * 1981-01-08 1985-08-14 Mitsui Toatsu Chemicals N-(4-phenyl-2-thiazolyl)carbamate derivatives, process for their preparation, and medicinal composition containing same
US4699928A (en) * 1984-07-13 1987-10-13 Merrell Dow Pharmaceuticals Inc. Fluoroallylamine derivatives
IT1181871B (it) * 1985-04-01 1987-09-30 Consiglio Nazionale Ricerche Inibitori selettivi delle benzilamminossidasi rispetto ad altre amminossidasi
US4916151A (en) * 1985-12-05 1990-04-10 Merrell Dow Pharmaceuticals Inc. Method of treating parkinson's syndrome
US4650907A (en) * 1985-12-05 1987-03-17 Merrell Dow Pharmaceuticals Inc. Nonaromatic fluoroallylamine MAO inhibitors
US5021456A (en) * 1988-02-25 1991-06-04 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US4943593A (en) * 1988-02-25 1990-07-24 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US4965288A (en) * 1988-02-25 1990-10-23 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5059814A (en) * 1988-11-30 1991-10-22 The California Institute Of Technology Winner-take-all circuits for neural computing systems
JPH0848664A (ja) * 1994-08-05 1996-02-20 Hisamitsu Pharmaceut Co Inc 新規なグアニジノ安息香酸エステル誘導体
GB9506188D0 (en) * 1995-03-27 1995-05-17 Fujisawa Pharmaceutical Co Amidine derivatives
JP2004502682A (ja) * 2000-07-05 2004-01-29 バイオティ　セラピーズ　コーポレイション 銅含有アミン・オキシダーゼの阻害剤
WO2002038153A1 (en) * 2000-11-09 2002-05-16 Biovitrum Ab New use of 4, 5, 6, 7-tetrahydroimidazo-[4,5-c]pyridine derivatives
EP1587800A1 (en) * 2003-01-27 2005-10-26 Astellas Pharma Inc. Thiazole derivatives and their use as vap-1 inhibitors
JP4758337B2 (ja) * 2003-03-31 2011-08-24 株式会社アールテック・ウエノ 血管透過性亢進疾患を治療する方法
WO2005089755A1 (en) * 2004-03-18 2005-09-29 R-Tech Ueno, Ltd. Aqueous composition comprising thiazole derivative

Similar Documents

Publication Publication Date Title
JP4978464B2 (ja) Ｖａｐ−１阻害剤活性を有するチアゾール誘導体
JP2008508188A5 (https=)
JP4650412B2 (ja) チアゾール誘導体およびｖａｐ−１阻害剤としてのその使用
AU2009209885B2 (en) Thiazole derivative and use thereof as VAP-1 inhibitor
JP4758337B2 (ja) 血管透過性亢進疾患を治療する方法
US20080015202A1 (en) Thiazole Derivatives Having Vap-1 Inhibitory Activity
JP2008512346A5 (https=)
US20110269953A1 (en) Nitrogen and Sulfur-Containing Heterocycle Derivatives