JP2008508188A5 - - Google Patents

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Publication number
JP2008508188A5
JP2008508188A5 JP2007504792A JP2007504792A JP2008508188A5 JP 2008508188 A5 JP2008508188 A5 JP 2008508188A5 JP 2007504792 A JP2007504792 A JP 2007504792A JP 2007504792 A JP2007504792 A JP 2007504792A JP 2008508188 A5 JP2008508188 A5 JP 2008508188A5
Authority
JP
Japan
Prior art keywords
thiazol
ethyl
phenyl
amino
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007504792A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008508188A (ja
JP4978464B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2005/014136 external-priority patent/WO2006011631A2/en
Publication of JP2008508188A publication Critical patent/JP2008508188A/ja
Publication of JP2008508188A5 publication Critical patent/JP2008508188A5/ja
Application granted granted Critical
Publication of JP4978464B2 publication Critical patent/JP4978464B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2007504792A 2004-07-27 2005-07-27 Ｖａｐ−１阻害剤活性を有するチアゾール誘導体 Expired - Fee Related JP4978464B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2004904196A AU2004904196A0 (en) 2004-07-27 Thiazole Derivatives Having VAP-1 Inhibitory Activity
AU2004904196 2004-07-27
PCT/JP2005/014136 WO2006011631A2 (en) 2004-07-27 2005-07-27 Thiazole derivatives having vap-1 inhibitory activity

Publications (3)

Publication Number Publication Date
JP2008508188A JP2008508188A (ja) 2008-03-21
JP2008508188A5 true JP2008508188A5 (https=) 2008-08-14
JP4978464B2 JP4978464B2 (ja) 2012-07-18

Family

ID=35734947

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007504792A Expired - Fee Related JP4978464B2 (ja) 2004-07-27 2005-07-27 Ｖａｐ−１阻害剤活性を有するチアゾール誘導体

Country Status (10)

Country Link
US (1) US20070254931A1 (https=)
EP (1) EP1786792B1 (https=)
JP (1) JP4978464B2 (https=)
KR (1) KR20070050932A (https=)
CN (1) CN101031555A (https=)
AT (1) ATE427941T1 (https=)
CA (1) CA2575411A1 (https=)
DE (1) DE602005013793D1 (https=)
ES (1) ES2324922T3 (https=)
WO (1) WO2006011631A2 (https=)

Families Citing this family (24)

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JP2009526868A (ja) * 2006-02-15 2009-07-23 アボット・ラボラトリーズ 新規なアセチル−ＣｏＡカルボキシラーゼ（ＡＣＣ）阻害薬およびこれらの糖尿病、肥満および代謝症候群における使用
CN101484433A (zh) 2006-02-15 2009-07-15 艾博特公司 新的乙酰辅酶a羧化酶(acc)抑制剂及其在糖尿病、肥胖症和代谢综合征中的应用
US20100190834A1 (en) * 2007-06-25 2010-07-29 R-Tech Ueno, Ltd. Composition for ophtalmic disease associated with hypoxia or ischemia
US20100210697A1 (en) * 2007-10-19 2010-08-19 R-Tech Ueno, Ltd. Pharmaceutical composition for treatment of cataract
US20090170770A1 (en) * 2007-11-06 2009-07-02 Ali Hafezi-Moghadam Methods and compositions for treating conditions associated with angiogenesis using a vascular adhesion protein-1 (vap 1) inhibitor
ES2442298T3 (es) * 2008-01-18 2014-02-11 Allergan, Inc. Agentes alfa 2 adrenérgicos selectivos de subtipo y métodos para usarlos
TWI437986B (zh) 2008-01-31 2014-05-21 R Tech Ueno Ltd 噻唑衍生物及使用該衍生物作為ｖａｐ－１抑制劑之用途
TWI490214B (zh) * 2008-05-30 2015-07-01 艾德克 上野股份有限公司 苯或噻吩衍生物及該等作為ｖａｐ－１抑制劑之用途
EA022417B1 (ru) * 2008-10-21 2015-12-30 Саймабэй Терапевтикс, Инк. Арильные агонисты рецептора gpr120 и их применение
UA112154C2 (uk) 2009-09-08 2016-08-10 Біоті Терапіс Корп. Застосування повністю людського анти-vap-1-антитіла для лікування фіброзних станів
FI20115234A0 (fi) 2011-03-08 2011-03-08 Biotie Therapies Corp Uusia pyridatsinoni- ja pyridoniyhdisteitä
LT3002278T (lt) * 2011-03-15 2017-06-26 Astellas Pharma Inc. Guanidino junginys
EP2781521A4 (en) 2011-10-19 2015-03-04 Kowa Co NEW SPIROINDOLIN COMPOUND AND MEDICAL AGENT THEREFOR
US20160113893A1 (en) 2013-06-12 2016-04-28 Proximagen Limited New therapeutic uses of enzyme inhibitors
EP3131539B1 (en) 2014-04-15 2018-12-05 Pécsi Tudományegyetem Semicarbazide-sensitive amine oxidase inhibitors for use as analgesics in traumatic neuropathy and neurogenic inflammation
WO2015189534A1 (en) 2014-06-12 2015-12-17 Proximagen Limited Vap-1 inhibitors for treating muscular dystrophy
CN104478828B (zh) * 2014-12-10 2016-07-06 漳州片仔癀药业股份有限公司 2-氨基-7-取代苯并噻唑类化合物及其制备方法与用途
JO3546B1 (ar) * 2015-01-09 2020-07-05 Kyowa Kirin Co Ltd طريقة لإنتاج مشتق ثيازول
JP2018076236A (ja) 2015-06-05 2018-05-17 株式会社アールテック・ウエノ がんを処置するための医薬組成物
AU2016301745B2 (en) 2015-08-06 2020-07-16 Ube Industries, Ltd. Substituted guanidine derivative
WO2017098236A1 (en) 2015-12-07 2017-06-15 Proximagen Limited Vap-1 inhibitors for treating pain
EP3455216B1 (en) * 2016-05-12 2020-11-04 Boehringer Ingelheim International GmbH Pyridinyl derivatives, pharmaceutical compositions and uses thereof as aoc3 inhibitors
LT3564230T (lt) 2016-12-28 2022-04-11 Ube Industries, Ltd. Pakeistas guanidino junginys
US10213306B2 (en) 2017-03-31 2019-02-26 Neochord, Inc. Minimally invasive heart valve repair in a beating heart

Family Cites Families (16)

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Publication number Priority date Publication date Assignee Title
EP0068033B1 (en) * 1981-01-08 1985-07-10 Mitsui Toatsu Kagaku Kabushiki Kaisha N-(4-phenyl-2-thiazolyl)carbamate derivatives, process for their preparation, and medicinal composition containing same
US4699928A (en) * 1984-07-13 1987-10-13 Merrell Dow Pharmaceuticals Inc. Fluoroallylamine derivatives
IT1181871B (it) * 1985-04-01 1987-09-30 Consiglio Nazionale Ricerche Inibitori selettivi delle benzilamminossidasi rispetto ad altre amminossidasi
US4916151A (en) * 1985-12-05 1990-04-10 Merrell Dow Pharmaceuticals Inc. Method of treating parkinson's syndrome
US4650907A (en) * 1985-12-05 1987-03-17 Merrell Dow Pharmaceuticals Inc. Nonaromatic fluoroallylamine MAO inhibitors
US4965288A (en) * 1988-02-25 1990-10-23 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5021456A (en) * 1988-02-25 1991-06-04 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US4943593A (en) * 1988-02-25 1990-07-24 Merrell Dow Pharmaceuticals Inc. Inhibitors of lysyl oxidase
US5059814A (en) * 1988-11-30 1991-10-22 The California Institute Of Technology Winner-take-all circuits for neural computing systems
JPH0848664A (ja) * 1994-08-05 1996-02-20 Hisamitsu Pharmaceut Co Inc 新規なグアニジノ安息香酸エステル誘導体
GB9506188D0 (en) * 1995-03-27 1995-05-17 Fujisawa Pharmaceutical Co Amidine derivatives
JP2004502682A (ja) * 2000-07-05 2004-01-29 バイオティ　セラピーズ　コーポレイション 銅含有アミン・オキシダーゼの阻害剤
AU2002214505A1 (en) * 2000-11-09 2002-05-21 Biovitrum Ab New use of 4, 5, 6, 7-tetrahydroimidazo-(4,5-c)pyridine derivatives
AR042941A1 (es) * 2003-01-27 2005-07-06 Fujisawa Pharmaceutical Co Derivados de tiazol, su preparacion, composiciones farmaceuticas que los contienen y su uso en la fabricacion de medicamentos inhibidores de la proteina-1 de adhesion vascular (vap-1)
US20060229346A1 (en) * 2003-03-31 2006-10-12 Sucampo Ag Method for treating vascular hyperpermeable disease
WO2005089755A1 (en) * 2004-03-18 2005-09-29 R-Tech Ueno, Ltd. Aqueous composition comprising thiazole derivative

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