JP2008506701A - 改変された組織マーキング顔料および組織マーキング顔料を改変するための方法 - Google Patents
改変された組織マーキング顔料および組織マーキング顔料を改変するための方法 Download PDFInfo
- Publication number
- JP2008506701A JP2008506701A JP2007521613A JP2007521613A JP2008506701A JP 2008506701 A JP2008506701 A JP 2008506701A JP 2007521613 A JP2007521613 A JP 2007521613A JP 2007521613 A JP2007521613 A JP 2007521613A JP 2008506701 A JP2008506701 A JP 2008506701A
- Authority
- JP
- Japan
- Prior art keywords
- pigment
- compound
- particles
- particle
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000049 pigment Substances 0.000 title claims abstract description 100
- 238000000034 method Methods 0.000 title claims abstract description 40
- 239000002245 particle Substances 0.000 claims abstract description 127
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 17
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 17
- 238000001179 sorption measurement Methods 0.000 claims abstract description 15
- 210000001519 tissue Anatomy 0.000 claims description 92
- 239000002158 endotoxin Substances 0.000 claims description 27
- 150000001875 compounds Chemical class 0.000 claims description 25
- 229920006008 lipopolysaccharide Polymers 0.000 claims description 21
- 229920001223 polyethylene glycol Polymers 0.000 claims description 21
- 239000002202 Polyethylene glycol Substances 0.000 claims description 20
- 210000004027 cell Anatomy 0.000 claims description 15
- 229920000642 polymer Polymers 0.000 claims description 11
- 239000011148 porous material Substances 0.000 claims description 10
- 102000004127 Cytokines Human genes 0.000 claims description 9
- 108090000695 Cytokines Proteins 0.000 claims description 9
- 238000000576 coating method Methods 0.000 claims description 8
- 230000000899 immune system response Effects 0.000 claims description 8
- 239000011248 coating agent Substances 0.000 claims description 7
- 102000005962 receptors Human genes 0.000 claims description 7
- 108020003175 receptors Proteins 0.000 claims description 7
- 229920003169 water-soluble polymer Polymers 0.000 claims description 7
- 102000006495 integrins Human genes 0.000 claims description 6
- 108010044426 integrins Proteins 0.000 claims description 6
- 150000002617 leukotrienes Chemical class 0.000 claims description 6
- 241000588724 Escherichia coli Species 0.000 claims description 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 4
- 241000605862 Porphyromonas gingivalis Species 0.000 claims description 4
- 238000007373 indentation Methods 0.000 claims description 4
- 229920002338 polyhydroxyethylmethacrylate Polymers 0.000 claims description 4
- MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical group OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 claims description 3
- 229920002732 Polyanhydride Polymers 0.000 claims description 3
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims description 3
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims description 3
- VNYSSYRCGWBHLG-AMOLWHMGSA-N leukotriene B4 Chemical group CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(O)=O VNYSSYRCGWBHLG-AMOLWHMGSA-N 0.000 claims description 3
- 210000003463 organelle Anatomy 0.000 claims description 2
- 239000004475 Arginine Substances 0.000 claims 1
- 230000004913 activation Effects 0.000 abstract 1
- 210000002865 immune cell Anatomy 0.000 abstract 1
- 230000028993 immune response Effects 0.000 description 10
- 206010018691 Granuloma Diseases 0.000 description 7
- 238000010586 diagram Methods 0.000 description 7
- 210000002540 macrophage Anatomy 0.000 description 7
- 239000000463 material Substances 0.000 description 7
- 230000004048 modification Effects 0.000 description 6
- 238000012986 modification Methods 0.000 description 6
- 210000004927 skin cell Anatomy 0.000 description 6
- 230000004044 response Effects 0.000 description 5
- 210000003491 skin Anatomy 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 210000000987 immune system Anatomy 0.000 description 4
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 3
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 3
- 210000002744 extracellular matrix Anatomy 0.000 description 3
- 238000002513 implantation Methods 0.000 description 3
- 101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 description 2
- 102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 description 2
- 230000020411 cell activation Effects 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 210000004905 finger nail Anatomy 0.000 description 2
- 239000007943 implant Substances 0.000 description 2
- 210000004324 lymphatic system Anatomy 0.000 description 2
- 210000003712 lysosome Anatomy 0.000 description 2
- 230000001868 lysosomic effect Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 239000011859 microparticle Substances 0.000 description 2
- 239000000178 monomer Substances 0.000 description 2
- 210000001539 phagocyte Anatomy 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000037390 scarring Effects 0.000 description 2
- 230000009919 sequestration Effects 0.000 description 2
- 210000004906 toe nail Anatomy 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 101710132601 Capsid protein Proteins 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 101710094648 Coat protein Proteins 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 102100021181 Golgi phosphoprotein 3 Human genes 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241000502522 Luscinia megarhynchos Species 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- 101710125418 Major capsid protein Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 101710141454 Nucleoprotein Proteins 0.000 description 1
- 101710083689 Probable capsid protein Proteins 0.000 description 1
- 208000031737 Tissue Adhesions Diseases 0.000 description 1
- YLEIFZAVNWDOBM-ZTNXSLBXSA-N ac1l9hc7 Chemical compound C([C@H]12)C[C@@H](C([C@@H](O)CC3)(C)C)[C@@]43C[C@@]14CC[C@@]1(C)[C@@]2(C)C[C@@H]2O[C@]3(O)[C@H](O)C(C)(C)O[C@@H]3[C@@H](C)[C@H]12 YLEIFZAVNWDOBM-ZTNXSLBXSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- SRVFFFJZQVENJC-IHRRRGAJSA-N aloxistatin Chemical compound CCOC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCCC(C)C SRVFFFJZQVENJC-IHRRRGAJSA-N 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 239000003575 carbonaceous material Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000036755 cellular response Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 210000004268 dentin Anatomy 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 210000004709 eyebrow Anatomy 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229910002804 graphite Inorganic materials 0.000 description 1
- 239000010439 graphite Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000002519 immonomodulatory effect Effects 0.000 description 1
- 229960001438 immunostimulant agent Drugs 0.000 description 1
- 239000003022 immunostimulating agent Substances 0.000 description 1
- 230000003308 immunostimulating effect Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 210000000554 iris Anatomy 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000003094 microcapsule Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000002445 nipple Anatomy 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 125000002524 organometallic group Chemical group 0.000 description 1
- 230000000242 pagocytic effect Effects 0.000 description 1
- 210000000680 phagosome Anatomy 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 230000032954 positive regulation of cell adhesion Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000000018 receptor agonist Substances 0.000 description 1
- 229940044601 receptor agonist Drugs 0.000 description 1
- 239000012925 reference material Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 210000003786 sclera Anatomy 0.000 description 1
- 239000002094 self assembled monolayer Substances 0.000 description 1
- 239000013545 self-assembled monolayer Substances 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/04—Preparations for care of the skin for chemically tanning the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/11—Encapsulated compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
- A61Q1/025—Semi-permanent tattoos, stencils, e.g. "permanent make-up"
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3937—Visible markers
- A61B2090/395—Visible markers with marking agent for marking skin or other tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Pigments, Carbon Blacks, Or Wood Stains (AREA)
- Medicinal Preparation (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
- Cosmetics (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
- Coloring (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58786404P | 2004-07-15 | 2004-07-15 | |
| PCT/US2005/024865 WO2006019823A2 (en) | 2004-07-15 | 2005-07-14 | Modified tissue marking pigment and method for modifying tissue marking pigment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008506701A true JP2008506701A (ja) | 2008-03-06 |
| JP2008506701A5 JP2008506701A5 (enExample) | 2008-09-11 |
Family
ID=35907879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007521613A Pending JP2008506701A (ja) | 2004-07-15 | 2005-07-14 | 改変された組織マーキング顔料および組織マーキング顔料を改変するための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20080028990A1 (enExample) |
| EP (1) | EP1786331A2 (enExample) |
| JP (1) | JP2008506701A (enExample) |
| AU (1) | AU2005275173A1 (enExample) |
| BR (1) | BRPI0513279A (enExample) |
| RU (1) | RU2007105589A (enExample) |
| WO (1) | WO2006019823A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2024518242A (ja) * | 2021-03-31 | 2024-05-01 | ザ リージェンツ オブ ザ ユニバーシティー オブ コロラド，ア ボディー コーポレート | 皮内使用のための多安定性フォトクロミック顔料 |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007115291A2 (en) * | 2006-04-04 | 2007-10-11 | Freedom-2, Inc. | Tissue markings with discrete absorption particles |
| US9295417B2 (en) | 2011-04-29 | 2016-03-29 | Seventh Sense Biosystems, Inc. | Systems and methods for collecting fluid from a subject |
| US9033898B2 (en) | 2010-06-23 | 2015-05-19 | Seventh Sense Biosystems, Inc. | Sampling devices and methods involving relatively little pain |
| US9041541B2 (en) | 2010-01-28 | 2015-05-26 | Seventh Sense Biosystems, Inc. | Monitoring or feedback systems and methods |
| CN104434136A (zh) | 2009-03-02 | 2015-03-25 | 第七感生物系统有限公司 | 用于抽出血液的装置 |
| WO2012018486A2 (en) | 2010-07-26 | 2012-02-09 | Seventh Sense Biosystems, Inc. | Rapid delivery and/or receiving of fluids |
| EP2593014B1 (en) | 2010-07-16 | 2015-11-04 | Seventh Sense Biosystems, Inc. | Low-pressure environment for fluid transfer devices |
| WO2012021801A2 (en) | 2010-08-13 | 2012-02-16 | Seventh Sense Biosystems, Inc. | Systems and techniques for monitoring subjects |
| WO2012064802A1 (en) | 2010-11-09 | 2012-05-18 | Seventh Sense Biosystems, Inc. | Systems and interfaces for blood sampling |
| US20130158468A1 (en) | 2011-12-19 | 2013-06-20 | Seventh Sense Biosystems, Inc. | Delivering and/or receiving material with respect to a subject surface |
| KR102013466B1 (ko) | 2011-04-29 | 2019-08-22 | 세븐쓰 센스 바이오시스템즈, 인크. | 유체들의 전달 및/또는 수용 |
| JP2014516644A (ja) | 2011-04-29 | 2014-07-17 | セブンス センス バイオシステムズ，インコーポレーテッド | 血斑または他の体液の収集および／または操作のためのデバイスおよび方法 |
| WO2013021357A1 (en) * | 2011-08-08 | 2013-02-14 | Ecole Polytechnique Federale De Lausanne (Epfl) | In-vivo condition monitoring of metallic implants by electrochemical techniques |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6013122A (en) * | 1998-08-18 | 2000-01-11 | Option Technologies, Inc. | Tattoo inks |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4159659A (en) * | 1978-05-16 | 1979-07-03 | Carol Nightingale | Electrical marking device |
| US4973468A (en) * | 1989-03-22 | 1990-11-27 | Cygnus Research Corporation | Skin permeation enhancer compositions |
| US5115805A (en) * | 1990-02-23 | 1992-05-26 | Cygnus Therapeutic Systems | Ultrasound-enhanced delivery of materials into and through the skin |
| US5543158A (en) * | 1993-07-23 | 1996-08-06 | Massachusetts Institute Of Technology | Biodegradable injectable nanoparticles |
| US5472449A (en) * | 1993-07-26 | 1995-12-05 | Chou; Kuei C. | Permanent pigment applicator having a detachable needle coupler |
| US5445611A (en) * | 1993-12-08 | 1995-08-29 | Non-Invasive Monitoring Company (Nimco) | Enhancement of transdermal delivery with ultrasound and chemical enhancers |
| US5814599A (en) * | 1995-08-04 | 1998-09-29 | Massachusetts Insitiute Of Technology | Transdermal delivery of encapsulated drugs |
| EP1131038A1 (en) * | 1998-11-20 | 2001-09-12 | The General Hospital Corporation | Permanent, removable tissue markings |
| US6254852B1 (en) * | 1999-07-16 | 2001-07-03 | Dupont Pharmaceuticals Company | Porous inorganic targeted ultrasound contrast agents |
-
2005
- 2005-07-14 JP JP2007521613A patent/JP2008506701A/ja active Pending
- 2005-07-14 EP EP05770972A patent/EP1786331A2/en not_active Withdrawn
- 2005-07-14 BR BRPI0513279-7A patent/BRPI0513279A/pt not_active IP Right Cessation
- 2005-07-14 WO PCT/US2005/024865 patent/WO2006019823A2/en not_active Ceased
- 2005-07-14 AU AU2005275173A patent/AU2005275173A1/en not_active Abandoned
- 2005-07-14 US US11/571,962 patent/US20080028990A1/en not_active Abandoned
- 2005-07-14 RU RU2007105589/04A patent/RU2007105589A/ru not_active Application Discontinuation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6013122A (en) * | 1998-08-18 | 2000-01-11 | Option Technologies, Inc. | Tattoo inks |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2024518242A (ja) * | 2021-03-31 | 2024-05-01 | ザ リージェンツ オブ ザ ユニバーシティー オブ コロラド，ア ボディー コーポレート | 皮内使用のための多安定性フォトクロミック顔料 |
| JP7705473B2 (ja) | 2021-03-31 | 2025-07-09 | ザ リージェンツ オブ ザ ユニバーシティー オブ コロラド，ア ボディー コーポレート | 皮内使用のための多安定性フォトクロミック顔料 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006019823A2 (en) | 2006-02-23 |
| WO2006019823A3 (en) | 2007-03-22 |
| EP1786331A2 (en) | 2007-05-23 |
| AU2005275173A1 (en) | 2006-02-23 |
| US20080028990A1 (en) | 2008-02-07 |
| BRPI0513279A (pt) | 2008-05-06 |
| RU2007105589A (ru) | 2008-08-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2020256382B2 (en) | Microarray for delivery of therapeutic agent and methods of use | |
| ES2851234T3 (es) | Dispositivos de suministro y métodos para aumento cutáneo | |
| JP2008506701A (ja) | 改変された組織マーキング顔料および組織マーキング顔料を改変するための方法 | |
| JP5563984B2 (ja) | 注射用アロプラスト皮膚充填材およびその使用方法 | |
| EP2450079B1 (en) | Needle-like material | |
| JP2002502413A (ja) | 創傷治療のための部材及び方法 | |
| JP2016506780A (ja) | マイクロニードル及びその製造用モールドならびにその製造方法 | |
| CA2644561A1 (en) | Fluidic tissue augmentation compositions and methods | |
| JP2021509344A (ja) | 皮膚増強のための高装填マイクロニードル及び組成物 | |
| WO2017177184A1 (en) | Removable tattoo ink and method of producing same | |
| Bernik | Silicon based materials for drug delivery devices and implants | |
| KR20160143611A (ko) | 경피전달용 미세돌기 구조체 | |
| KR102334072B1 (ko) | 경피 전달용 색소 마이크로구조체 | |
| CN119700713B (zh) | 一种双层嵌套结构微针及其应用 | |
| Yellepeddi et al. | Nanotechnology-based applications for transdermal delivery of therapeutics | |
| GB2639767A (en) | Microneedle devices for delivery of agents into the skin | |
| KR20200062097A (ko) | 마이크로 스피큘, 이의 제조용 몰드 및 이의 제조 방법 | |
| KR20210029884A (ko) | 안전성이 향상된 조직확장기의 표면 코팅방법 | |
| HK1210728B (zh) | 用於皮肤改善的递送装置和方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A712 Effective date: 20071210 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20080711 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20080728 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20110315 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20110510 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20110804 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20110811 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20120124 |