JP2008505163A5 - - Google Patents
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- Publication number
- JP2008505163A5 JP2008505163A5 JP2007519787A JP2007519787A JP2008505163A5 JP 2008505163 A5 JP2008505163 A5 JP 2008505163A5 JP 2007519787 A JP2007519787 A JP 2007519787A JP 2007519787 A JP2007519787 A JP 2007519787A JP 2008505163 A5 JP2008505163 A5 JP 2008505163A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- alkoxy
- methyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 150000001875 compounds Chemical class 0.000 claims 14
- -1 phosphino group Chemical group 0.000 claims 10
- 229910052740 iodine Inorganic materials 0.000 claims 9
- 239000003446 ligand Substances 0.000 claims 8
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 8
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 8
- 229910052739 hydrogen Inorganic materials 0.000 claims 7
- 239000001257 hydrogen Substances 0.000 claims 7
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 7
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 6
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 5
- 239000002253 acid Substances 0.000 claims 4
- 150000004696 coordination complex Chemical class 0.000 claims 4
- 229910052751 metal Inorganic materials 0.000 claims 4
- 239000002184 metal Substances 0.000 claims 4
- 150000002894 organic compounds Chemical class 0.000 claims 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 3
- 125000000129 anionic group Chemical group 0.000 claims 3
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 3
- 125000001183 hydrocarbyl group Chemical group 0.000 claims 3
- 125000001424 substituent group Chemical group 0.000 claims 3
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 2
- 150000001450 anions Chemical class 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- CREMABGTGYGIQB-UHFFFAOYSA-N carbon carbon Chemical compound C.C CREMABGTGYGIQB-UHFFFAOYSA-N 0.000 claims 2
- 239000011203 carbon fibre reinforced carbon Substances 0.000 claims 2
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 2
- 125000000058 cyclopentadienyl group Chemical group C1(=CC=CC1)* 0.000 claims 2
- 150000002431 hydrogen Chemical group 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 229910052741 iridium Inorganic materials 0.000 claims 2
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 2
- 230000003647 oxidation Effects 0.000 claims 2
- 238000007254 oxidation reaction Methods 0.000 claims 2
- 229910052703 rhodium Inorganic materials 0.000 claims 2
- 229910052707 ruthenium Inorganic materials 0.000 claims 2
- 239000007983 Tris buffer Substances 0.000 claims 1
- 125000002015 acyclic group Chemical group 0.000 claims 1
- 125000002252 acyl group Chemical group 0.000 claims 1
- 238000007259 addition reaction Methods 0.000 claims 1
- 125000002723 alicyclic group Chemical group 0.000 claims 1
- 125000001931 aliphatic group Chemical group 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 150000001721 carbon Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 239000003054 catalyst Substances 0.000 claims 1
- 230000003197 catalytic effect Effects 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 229910052802 copper Inorganic materials 0.000 claims 1
- 125000004122 cyclic group Chemical group 0.000 claims 1
- 125000005745 ethoxymethyl group Chemical group [H]C([H])([H])C([H])([H])OC([H])([H])* 0.000 claims 1
- 229910052737 gold Inorganic materials 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 239000002815 homogeneous catalyst Substances 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 150000004715 keto acids Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 150000002739 metals Chemical class 0.000 claims 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229910052759 nickel Inorganic materials 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 125000002868 norbornyl group Chemical group C12(CCC(CC1)C2)* 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 229910052763 palladium Inorganic materials 0.000 claims 1
- FVZVCSNXTFCBQU-UHFFFAOYSA-N phosphanyl Chemical group [PH2] FVZVCSNXTFCBQU-UHFFFAOYSA-N 0.000 claims 1
- 229910052697 platinum Inorganic materials 0.000 claims 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 229910052709 silver Inorganic materials 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 125000004434 sulfur atom Chemical group 0.000 claims 1
- GBXQPDCOMJJCMJ-UHFFFAOYSA-M trimethyl-[6-(trimethylazaniumyl)hexyl]azanium;bromide Chemical compound [Br-].C[N+](C)(C)CCCCCC[N+](C)(C)C GBXQPDCOMJJCMJ-UHFFFAOYSA-M 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH11262004 | 2004-07-05 | ||
| CH17732004 | 2004-10-26 | ||
| CH18532004 | 2004-11-10 | ||
| PCT/EP2005/053171 WO2006003196A1 (de) | 2004-07-05 | 2005-07-04 | 1,1'diphosphinoferrocene mit 2,2'-gebundenen achiralen oder chiralen resten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008505163A JP2008505163A (ja) | 2008-02-21 |
| JP2008505163A5 true JP2008505163A5 (enExample) | 2008-08-21 |
Family
ID=34971657
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007519787A Withdrawn JP2008505163A (ja) | 2004-07-05 | 2005-07-04 | 2,2’位結合のアキラルまたはキラル基を有する1,1−ジホスフィノフェロセン |
| JP2007519786A Withdrawn JP2008505162A (ja) | 2004-07-05 | 2005-07-04 | 四座フェロセン配位子およびそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007519786A Withdrawn JP2008505162A (ja) | 2004-07-05 | 2005-07-04 | 四座フェロセン配位子およびそれらの使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20080026933A1 (enExample) |
| EP (2) | EP1765840A1 (enExample) |
| JP (2) | JP2008505163A (enExample) |
| AT (1) | ATE375356T1 (enExample) |
| CA (2) | CA2572650A1 (enExample) |
| DE (1) | DE502005001692D1 (enExample) |
| ES (1) | ES2293596T3 (enExample) |
| IL (2) | IL180429A0 (enExample) |
| WO (2) | WO2006003196A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0400720D0 (en) * | 2004-01-14 | 2004-02-18 | Stylacats Ltd | Novel ferrocene-based phosphorus chiral phosphines |
| WO2007020221A2 (en) * | 2005-08-12 | 2007-02-22 | Solvias Ag | Amino-phosphinoalkyl-ferrocenes and their use as ligands in catalysts for asymmetric reactions |
| JP5320283B2 (ja) * | 2006-04-12 | 2013-10-23 | ソルヴィーアス アクチェンゲゼルシャフト | フェロセンジホスフィン |
| WO2007135179A1 (en) * | 2006-05-23 | 2007-11-29 | Solvias Ag | Chiral ligands used in transition metal catalysts for asymmetric addition reactions especially hydrogenation |
| EP1903027A1 (en) * | 2006-09-13 | 2008-03-26 | Novartis AG | Process for preparing biaryl substituted 4-amino-butyric acid or derivatives thereof and their use in the production of NEP inhibitors |
| WO2008034809A1 (en) * | 2006-09-19 | 2008-03-27 | Solvias Ag | Diphosphines and metal complexes |
| DE102007028238A1 (de) * | 2007-06-20 | 2008-12-24 | Osram Opto Semiconductors Gmbh | Verwendung eines Metallkomplexes als p-Dotand für ein organisches halbleitendes Matrixmaterial, organisches Halbleitermaterial und organische Leuchtdiode |
| US8680278B2 (en) * | 2007-10-30 | 2014-03-25 | Janssen Pharmaceutica Nv | Enantioselective process for preparing a substituted alkanoic acid |
| CN101565366B (zh) * | 2008-04-25 | 2013-04-17 | 浙江九洲药业股份有限公司 | 铱络合物在不饱和羧酸不对称催化氢化中的应用 |
| WO2014164801A1 (en) * | 2013-03-11 | 2014-10-09 | Rutgers, The State University Of New Jersey | Metallorganocatalysis for asymmetric transformations |
| CN112480179B (zh) * | 2020-11-24 | 2025-11-14 | 苏州鹏旭医药科技有限公司 | 一种取代二茂铁基二膦均相催化剂配体 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE223925T1 (de) * | 1996-04-25 | 2002-09-15 | Hoechst Ag | 2,2'-disubstituierte 1,1'-diphosphino-ferrocene und 1',2-disubstituierte 1-phosphino-ferrocene, verfahren zu ihrer herstellung, ihre verwendung sowie sie enthaltende übergangsmetallkomplexe |
| DE19921924A1 (de) * | 1998-06-19 | 1999-12-23 | Degussa | Verwendung von Ferrocenylliganden zur katalytischen enantioselektiven Hydrierung |
| ATE394941T1 (de) * | 1999-07-28 | 2008-05-15 | Swiss Caps Rechte & Lizenzen | Präparat zur verwendung als medikament und/oder nahrungsmittelergänzung |
| US6590115B2 (en) * | 2000-09-29 | 2003-07-08 | Eastman Chemical Company | Phosphino-aminophosphines |
-
2005
- 2005-07-04 CA CA002572650A patent/CA2572650A1/en not_active Abandoned
- 2005-07-04 AT AT05773938T patent/ATE375356T1/de not_active IP Right Cessation
- 2005-07-04 JP JP2007519787A patent/JP2008505163A/ja not_active Withdrawn
- 2005-07-04 EP EP05758688A patent/EP1765840A1/en not_active Withdrawn
- 2005-07-04 US US11/631,608 patent/US20080026933A1/en not_active Abandoned
- 2005-07-04 WO PCT/EP2005/053171 patent/WO2006003196A1/de not_active Ceased
- 2005-07-04 CA CA002572653A patent/CA2572653A1/en not_active Abandoned
- 2005-07-04 JP JP2007519786A patent/JP2008505162A/ja not_active Withdrawn
- 2005-07-04 ES ES05773938T patent/ES2293596T3/es not_active Expired - Lifetime
- 2005-07-04 WO PCT/EP2005/053170 patent/WO2006003195A1/en not_active Ceased
- 2005-07-04 DE DE502005001692T patent/DE502005001692D1/de not_active Expired - Fee Related
- 2005-07-04 US US11/631,687 patent/US20080076937A1/en not_active Abandoned
- 2005-07-04 EP EP05773938A patent/EP1763532B1/de not_active Expired - Lifetime
-
2006
- 2006-12-28 IL IL180429A patent/IL180429A0/en unknown
- 2006-12-28 IL IL180421A patent/IL180421A0/en unknown
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