JP2008504365A5 - - Google Patents

Download PDF

Info

Publication number
JP2008504365A5
JP2008504365A5 JP2007519285A JP2007519285A JP2008504365A5 JP 2008504365 A5 JP2008504365 A5 JP 2008504365A5 JP 2007519285 A JP2007519285 A JP 2007519285A JP 2007519285 A JP2007519285 A JP 2007519285A JP 2008504365 A5 JP2008504365 A5 JP 2008504365A5
Authority
JP
Japan
Prior art keywords
compound according
meta
compound
phenyl ring
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007519285A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008504365A (ja
Filing date
Publication date
Priority claimed from US10/878,138 external-priority patent/US6989443B2/en
Application filed filed Critical
Publication of JP2008504365A publication Critical patent/JP2008504365A/ja
Publication of JP2008504365A5 publication Critical patent/JP2008504365A5/ja
Pending legal-status Critical Current

Links

JP2007519285A 2004-06-28 2005-06-22 カルボラニルポルフィリン及びそれらの使用 Pending JP2008504365A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/878,138 US6989443B2 (en) 2004-06-28 2004-06-28 Carboranylporphyrins and uses thereof
PCT/US2005/022061 WO2006012140A1 (en) 2004-06-28 2005-06-22 Carboranylporphyrins and uses thereof

Publications (2)

Publication Number Publication Date
JP2008504365A JP2008504365A (ja) 2008-02-14
JP2008504365A5 true JP2008504365A5 (cg-RX-API-DMAC7.html) 2008-08-07

Family

ID=35505984

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007519285A Pending JP2008504365A (ja) 2004-06-28 2005-06-22 カルボラニルポルフィリン及びそれらの使用

Country Status (11)

Country Link
US (1) US6989443B2 (cg-RX-API-DMAC7.html)
EP (1) EP1778082A4 (cg-RX-API-DMAC7.html)
JP (1) JP2008504365A (cg-RX-API-DMAC7.html)
KR (1) KR20070033006A (cg-RX-API-DMAC7.html)
CN (1) CN1988848B (cg-RX-API-DMAC7.html)
AU (1) AU2005267390B2 (cg-RX-API-DMAC7.html)
CA (1) CA2572287A1 (cg-RX-API-DMAC7.html)
IL (1) IL180365A (cg-RX-API-DMAC7.html)
NO (1) NO20070509L (cg-RX-API-DMAC7.html)
NZ (1) NZ552877A (cg-RX-API-DMAC7.html)
WO (1) WO2006012140A1 (cg-RX-API-DMAC7.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070093463A1 (en) * 2004-05-20 2007-04-26 Brookhaven Science Associates, Llc Radiation enhancement agent for X-ray radiation therapy and boron neutron-capture therapy
US8287839B2 (en) * 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US8444953B2 (en) * 2007-03-22 2013-05-21 Brookhaven Science Associates, Llc Symmetric and asymmetric halogen-containing metallocarboranylporphyrins and uses thereof
US20080279781A1 (en) * 2007-05-10 2008-11-13 Brookhaven Science Associates, Llc Glycosylated Carboranylporphyrins and Uses Thereof
WO2011034183A1 (ja) * 2009-09-17 2011-03-24 国立大学法人九州大学 ポルフィリン化合物
CN102260269B (zh) * 2010-05-25 2013-11-06 苏州和健医药科技有限公司 一种含有卟啉或二氢卟吩的树状化合物及其应用
GB201212409D0 (en) 2012-07-12 2012-08-22 Morex Dev Partners Llp Cancer treatment
JP6699004B2 (ja) * 2015-08-25 2020-05-27 住友重機械工業株式会社 中性子捕捉療法システム及び中性子捕捉療法システムの制御方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783529A (en) * 1985-12-03 1988-11-08 Research Corporation Technologies Rapid synthesis of radiolabeled porphyrin complexes for medical application
US5162231A (en) * 1989-10-25 1992-11-10 Cole Dean A Method of using 5,10,15,20-tetrakis(carboxyphenyl)porphine for detecting cancers of the lung
US4959356A (en) * 1989-05-26 1990-09-25 The United States Of America As Represented By The United States Department Of Energy Porphyrins for boron neutron capture therapy
FR2656866B1 (fr) * 1990-01-10 1992-05-15 Cis Bio Int Derives de porphyrine et metalloporphyrines eventuellement couples a une molecule biologiquement active, et composition pharmaceutique les contenant.
US5654423A (en) * 1990-11-21 1997-08-05 Regents Of The University Of California Boronated metalloporphyrine and therapeutic methods
US5149801A (en) * 1990-11-21 1992-09-22 The Regents Of The University Of California Boronated porphyrin compounds
US5312896A (en) * 1992-10-09 1994-05-17 Sri International Metal ion porphyrin-containing poly(imide)
DE4305523A1 (de) * 1993-02-17 1994-08-18 Diagnostikforschung Inst Meso-Tetraphenylporphyrin-Komplexverbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
IT232801Y1 (it) * 1994-03-07 2000-01-19 Imbac Spa Fianco di cassonetto con gambo laterale di innesto asportabile e intercambiabile
US5563132A (en) * 1994-06-21 1996-10-08 Bodaness; Richard S. Two-step cancer treatment method
US5877165A (en) * 1995-11-02 1999-03-02 Brookhaven Science Associates Boronated porhyrins and methods for their use
US5955586A (en) 1996-03-22 1999-09-21 Sessler; Jonathan L. Highly boronated derivatives of texaphyrins
WO1998030102A1 (en) * 1997-01-09 1998-07-16 Emory University Non-iron metalloporphyrins and methods of use
US6010805A (en) * 1998-05-26 2000-01-04 United States Of America As Represented By The Secretary Of The Air Force Ion conducting electrolyte material containing a lithium porphyrin complex
US7067653B2 (en) 2000-05-09 2006-06-27 The Regents Of The University Of California Porphyrin Based neuton capture agents for cancer therapy
EP1404319B1 (en) * 2001-06-06 2006-03-22 Brookhaven Science Associates Novel metalloporphyrins and their uses as radiosensitizers for radiation therapy
US6566517B2 (en) * 2001-06-06 2003-05-20 Brookhaven Science Associates, Llc Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy

Similar Documents

Publication Publication Date Title
JP2010511704A5 (cg-RX-API-DMAC7.html)
RU2009121323A (ru) Карборанилпорферины и их применение
Barth et al. Evaluation of sodium borocaptate (BSH) and boronophenylalanine (BPA) as boron delivery agents for neutron capture therapy (NCT) of cancer: an update and a guide for the future clinical evaluation of new boron delivery agents for NCT
Futamura et al. Evaluation of a novel sodium borocaptate-containing unnatural amino acid as a boron delivery agent for neutron capture therapy of the F98 rat glioma
JP2008505983A5 (cg-RX-API-DMAC7.html)
JP4954417B2 (ja) 放射性白金で標識した化学療法薬の合成法および用途
Oshiro et al. High-dose concurrent chemo–proton therapy for Stage III NSCLC: preliminary results of a Phase II study
CN1279907C (zh) 新的金属卟啉化合物及其在放射疗法中用作放射增敏剂的用途
Kuroiwaª et al. Boron neutron capture therapy of malignant gliomas
Louw et al. Evaluation of samarium-153 and holmium-166-EDTMP in the normal baboon model
Fukuda et al. Boron neutron capture therapy (BNCT) for malignant melanoma with special reference to absorbed doses to the normal skin and tumor
Masunaga et al. The dependency of compound biological effectiveness factors on the type and the concentration of administered neutron capture agents in boron neutron capture therapy
Heber et al. Boron delivery with liposomes for boron neutron capture therapy (BNCT): biodistribution studies in an experimental model of oral cancer demonstrating therapeutic potential
Futamura et al. A case of radiation-induced osteosarcoma treated effectively by boron neutron capture therapy
JP2008504365A5 (cg-RX-API-DMAC7.html)
Lee et al. In vivo evaluation of the effects of combined boron and gadolinium neutron capture therapy in mouse models
Garabalino et al. Boron neutron capture therapy (BNCT) for the treatment of liver metastases: biodistribution studies of boron compounds in an experimental model
Fuwa et al. Treatment results of boron neutron capture therapy using intra-arterial administration of boron compounds for recurrent head and neck cancer
JP6170147B2 (ja) 癌治療
Zhang et al. Pharmacokinetic, biodistribution, safety and efficacy studies of borophenylalanine (BPA) in BNCT in hepatocellular carcinoma cells and tumor-bearing mouse model
CA2572287A1 (en) Carboranylporphyrins and uses thereof
Fujibayashi et al. Imaging and therapy against hypoxic tumors with 64Cu-ATSM
Quah Boron neutron capture therapy in the treatment of lung cancer
Brandão et al. Intracavitary moderator balloon combined with 252Cf brachytherapy and boron neutron capture therapy, improving dosimetry in brain tumour and infiltrations
MacDonald et al. PET/CT aids the staging of and radiotherapy planning for early-stage extranodal natural killer/T-cell lymphoma, nasal type: a case series