JP2008503582A5 - - Google Patents
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- Publication number
- JP2008503582A5 JP2008503582A5 JP2007518185A JP2007518185A JP2008503582A5 JP 2008503582 A5 JP2008503582 A5 JP 2008503582A5 JP 2007518185 A JP2007518185 A JP 2007518185A JP 2007518185 A JP2007518185 A JP 2007518185A JP 2008503582 A5 JP2008503582 A5 JP 2008503582A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- excipient
- pharmaceutically acceptable
- pharmaceutical composition
- acceptable carrier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 19
- 239000003937 drug carrier Substances 0.000 claims 9
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 239000000546 pharmaceutical excipient Substances 0.000 claims 9
- 125000000524 functional group Chemical group 0.000 claims 6
- 125000000896 monocarboxylic acid group Chemical group 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 125000003118 aryl group Chemical group 0.000 claims 3
- 125000000753 cycloalkyl group Chemical group 0.000 claims 3
- 230000002378 acidificating effect Effects 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical group NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 150000003512 tertiary amines Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58141204P | 2004-06-21 | 2004-06-21 | |
| US60/581,412 | 2004-06-21 | ||
| PCT/US2005/021826 WO2006002105A1 (en) | 2004-06-21 | 2005-06-21 | Anticancer and antiprotozoal dihydroartemisinene and dihydroartemisitene dimers with desirable chemical functionalities |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008503582A JP2008503582A (ja) | 2008-02-07 |
| JP2008503582A5 true JP2008503582A5 (enExample) | 2008-08-14 |
| JP5140416B2 JP5140416B2 (ja) | 2013-02-06 |
Family
ID=35782123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007518185A Expired - Fee Related JP5140416B2 (ja) | 2004-06-21 | 2005-06-21 | 望ましい化学的官能基を有する抗がん及び抗原虫ジヒドロアーテミシニン及びジヒドロアーテミシテンダイマー |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7842720B2 (enExample) |
| EP (1) | EP1753419B1 (enExample) |
| JP (1) | JP5140416B2 (enExample) |
| AU (1) | AU2005258005B2 (enExample) |
| CA (1) | CA2570961C (enExample) |
| MX (1) | MXPA06015060A (enExample) |
| WO (1) | WO2006002105A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2899586B1 (fr) * | 2006-04-11 | 2008-06-20 | Sanofi Aventis Sa | Dimeres de derives d'artemisinine, leur preparation et leur application en therapeutique |
| US20100292472A1 (en) * | 2008-01-23 | 2010-11-18 | Tomoko Toyama | Prophylactic and therapeutic medicine for malaria |
| US9422306B2 (en) | 2012-12-21 | 2016-08-23 | University Of Washington Through Its Center For Commercialization | Artemisinin compounds and synthesis and use thereof |
| MX2021007437A (es) * | 2018-12-21 | 2021-09-08 | Terran Biosciences Inc | Formas deuteradas y derivados de volinanserina. |
| CA3124627A1 (en) * | 2018-12-24 | 2020-07-02 | Upl Ltd | Process for preparation of anthranilamides |
| CA3131244A1 (en) * | 2019-02-26 | 2020-09-03 | Mahmoud A. Eisohly | Selected artemisinin dimers for the treatment of lashmaniasis |
| KR102338609B1 (ko) * | 2019-05-20 | 2021-12-14 | 보령제약 주식회사 | 피리도-피리미딘 화합물 및 이를 유효성분으로 포함하는 pi3k 관련 질환의 예방 또는 치료용 약학적 조성물 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5840925A (en) * | 1995-06-29 | 1998-11-24 | Hauser, Inc. | Trioxane dimer compounds having antiproliferative and antitumor activities |
| US5677468A (en) * | 1995-06-29 | 1997-10-14 | Hauser, Inc. | Artemisinin dimer compounds having anticancer activity |
| CN1084333C (zh) | 1998-06-17 | 2002-05-08 | 中国科学院上海药物研究所 | 新的青蒿素化合物,其制备方法以及含有它们的药物组合物 |
| US6878751B1 (en) * | 2000-10-19 | 2005-04-12 | Imperial College Of Science Technology And Medicine | Administration of resveratrol to treat inflammatory respiratory disorders |
| FR2831538B1 (fr) | 2001-10-26 | 2004-01-16 | Centre Nat Rech Scient | Nouveaux derives de l'artemisinine, et leurs utilisations dans le traitement du paludisme |
| US7417156B2 (en) | 2002-09-27 | 2008-08-26 | Johns Hopkins University | Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers |
| US6790863B2 (en) * | 2002-10-15 | 2004-09-14 | University Of Mississippi | Dihydroartemisinin and dihydroartemisitene dimers as anti-cancer and anti-infective agents |
-
2005
- 2005-06-21 JP JP2007518185A patent/JP5140416B2/ja not_active Expired - Fee Related
- 2005-06-21 MX MXPA06015060A patent/MXPA06015060A/es active IP Right Grant
- 2005-06-21 EP EP05762351.4A patent/EP1753419B1/en not_active Expired - Lifetime
- 2005-06-21 AU AU2005258005A patent/AU2005258005B2/en not_active Ceased
- 2005-06-21 US US11/570,652 patent/US7842720B2/en not_active Expired - Fee Related
- 2005-06-21 CA CA2570961A patent/CA2570961C/en not_active Expired - Fee Related
- 2005-06-21 WO PCT/US2005/021826 patent/WO2006002105A1/en not_active Ceased