JP2008500373A - ケルベロス（Ｃｅｒｂｅｒｕｓ）／ココ（Ｃｏｃｏ）誘導体およびそれらの使用 - Google Patents
ケルベロス（Ｃｅｒｂｅｒｕｓ）／ココ（Ｃｏｃｏ）誘導体およびそれらの使用 Download PDFInfo
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- C07—ORGANIC CHEMISTRY
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| US57506204P | 2004-05-27 | 2004-05-27 | |
| PCT/US2005/018928 WO2005115439A2 (en) | 2004-05-27 | 2005-05-27 | Cerberus/coco derivatives and uses thereof |
Publications (2)
| Publication Number | Publication Date |
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| JP2008500373A true JP2008500373A (ja) | 2008-01-10 |
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| EP (1) | EP1755648A2 (https=) |
| JP (1) | JP2008500373A (https=) |
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| CA (1) | CA2567810A1 (https=) |
| IL (1) | IL179602A0 (https=) |
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| US9045553B2 (en) * | 2004-05-27 | 2015-06-02 | Acceleron Pharma, Inc. | Cerberus/Coco derivatives and uses thereof |
| WO2007123391A1 (en) | 2006-04-20 | 2007-11-01 | Academisch Ziekenhuis Leiden | Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly expressed gene. |
| SI2049664T1 (sl) | 2006-08-11 | 2012-04-30 | Prosensa Technologies Bv | Enojna veriga oligonukleotidov, komplementarna repetitivnim elementom, za zdravljenje genetskih bolezni, povezanih z nestabilnostjo dnk ponovitev |
| CA2671983A1 (en) | 2006-12-08 | 2009-06-19 | Acceleron Pharma Inc. | Uses of cerberus, coco and derivatives thereof |
| EA018221B1 (ru) * | 2007-02-09 | 2013-06-28 | Акселерон Фарма Инк. | АНТАГОНИСТЫ АКТИВИНА-ActRIIa И ПРИМЕНЕНИЕ ДЛЯ СТИМУЛЯЦИИ РОСТА КОСТИ У БОЛЬНЫХ РАКОМ |
| WO2008106478A1 (en) * | 2007-02-27 | 2008-09-04 | Lanx, Llc | Compositions and methods for modification of target cells and to their uses thereof |
| US20100150881A1 (en) * | 2007-06-01 | 2010-06-17 | Lanx, Inc. | Compositions and Methods for Use of Scar Tissue in Repair of Weight Bearing Surfaces |
| ES2639852T3 (es) | 2007-10-26 | 2017-10-30 | Academisch Ziekenhuis Leiden | Medios y métodos para contrarrestar los trastornos musculares |
| USRE48468E1 (en) | 2007-10-26 | 2021-03-16 | Biomarin Technologies B.V. | Means and methods for counteracting muscle disorders |
| WO2009105606A1 (en) * | 2008-02-21 | 2009-08-27 | Lanx, Llc | Compositions and methods for use of scar tissue in repair of weight bearing surfaces |
| EP2119783A1 (en) | 2008-05-14 | 2009-11-18 | Prosensa Technologies B.V. | Method for efficient exon (44) skipping in Duchenne Muscular Dystrophy and associated means |
| US9149319B2 (en) * | 2008-09-23 | 2015-10-06 | Lanx, Llc | Methods and compositions for stabilization of a vertebra |
| EP2421971B1 (en) | 2009-04-24 | 2016-07-06 | BioMarin Technologies B.V. | Oligonucleotide comprising an inosine for treating dmd |
| KR20120049214A (ko) | 2009-06-08 | 2012-05-16 | 악셀레론 파마 인코포레이티드 | 발열성 지방세포를 증가시키는 방법 |
| AU2010260145B2 (en) * | 2009-06-15 | 2015-08-20 | Valerion Therapeutics, Llc | Methods and compositions for treatment of Myotubular Myopathy using chimeric polypeptides comprising myotubularin 1 (MTM1) polypeptides |
| AU2010315245B2 (en) | 2009-11-03 | 2016-11-03 | Acceleron Pharma Inc. | Methods for treating fatty liver disease |
| DE102010052941A1 (de) * | 2010-11-18 | 2012-05-24 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Therapeutisches Protein |
| NZ627896A (en) | 2012-01-27 | 2016-11-25 | Biomarin Technologies B V | Rna modulating oligonucleotides with improved characteristics for the treatment of duchenne and becker muscular dystrophy |
| RS61778B1 (sr) | 2013-05-06 | 2021-06-30 | Scholar Rock Inc | Kompozicije i postupci za modulaciju faktora rasta |
| EP3741375A1 (en) * | 2014-07-17 | 2020-11-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for treating neuromuscular junction-related diseases |
| EP3215175A4 (en) | 2014-11-06 | 2018-06-27 | Scholar Rock, Inc. | Anti-pro/latent-myostatin antibodies and uses thereof |
| HRP20211081T1 (hr) | 2015-09-15 | 2021-10-15 | Scholar Rock, Inc. | Anti-pro/latentna miostatinska protutijela i njihove uporabe |
| CN115814077A (zh) | 2016-01-08 | 2023-03-21 | 供石公司 | 抗-原肌生长抑制素/潜伏肌生长抑制素抗体及其使用方法 |
| WO2017177013A1 (en) | 2016-04-06 | 2017-10-12 | Acceleron Pharma Inc. | Alk7 antagonists and uses thereof |
| NZ789269A (en) | 2016-06-13 | 2026-01-30 | Scholar Rock Inc | Use of myostatin inhibitors and combination therapies |
| EP4218817A3 (en) * | 2017-01-06 | 2023-09-06 | Scholar Rock, Inc. | Methods for treating metabolic diseases by inhibiting myostatin activation |
| CN109758616B (zh) * | 2019-03-05 | 2021-11-19 | 中国医学科学院北京协和医院 | 一种新型促进骨再生材料及其制备方法 |
| EP4638496A1 (en) | 2022-12-22 | 2025-10-29 | Scholar Rock, Inc. | Selective and potent inhibitory antibodies of myostatin activation |
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| WO2003072714A2 (en) * | 2002-02-21 | 2003-09-04 | Wyeth | Follistatin domain containing proteins |
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| US6133232A (en) * | 1996-06-20 | 2000-10-17 | The Regents Of The University Of California | Endoderm, cardiac and neural inducing factors |
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| US5935852A (en) | 1997-07-03 | 1999-08-10 | Genetics Institute, Inc. | DNA molecules encoding mammalian cerberus-like proteins |
| US6656475B1 (en) | 1997-08-01 | 2003-12-02 | The Johns Hopkins University School Of Medicine | Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same |
| CA2319703C (en) | 1998-02-05 | 2005-09-20 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-8 |
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| WO2002078516A2 (en) | 2001-03-30 | 2002-10-10 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of cancer |
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| US6513196B2 (en) | 2001-06-22 | 2003-02-04 | Maytag Corporation | Top cover hinge and method for using same |
| CN1161875C (zh) | 2001-07-01 | 2004-08-11 | 周符明 | 开关稳功率电源 |
| GB0118223D0 (en) | 2001-07-26 | 2001-09-19 | Univ Sheffield | Stem loop RNA |
| KR100996226B1 (ko) | 2001-10-31 | 2010-11-24 | 유니버시티 오브 노스 텍사스 헬스 사이언스 센터 | 뼈 형태발생 단백질(ｂｍｐ), ｂｍｐ 수용체 및 ｂｍｐ결합 단백질 및 녹내장 진단 및 치료에서 그의 용도 |
| GB0130738D0 (en) | 2001-12-21 | 2002-02-06 | Serono Internat S A | Protein |
| US20030134790A1 (en) | 2002-01-11 | 2003-07-17 | University Of Medicine And Dentistry Of New Jersey | Bone Morphogenetic Protein-2 And Bone Morphogenetic Protein-4 In The Treatment And Diagnosis Of Cancer |
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| BR0317538A (pt) * | 2002-12-20 | 2005-11-29 | Amgen Inc | Agente ligante, sequência de polinucleotìdeo, vetor de expressão, célula hospedeira, composição farmacêutica, e, métodos de inibir a atividade de miostatina, de aumentar a massa muscular magra e a razão de massa muscular magra para gordura, de tratar uma doença de emaciação muscular e um distúrbio metabólico relacionado com miostatina em um indivìduo, de detectar e medir miostatina em uma amostra, e, de diagnosticar um distúrbio relacionado com miostatina em um indivìduo |
| WO2004074460A2 (en) | 2003-02-19 | 2004-09-02 | The Rockefeller University | Nucleotide and protein sequences of coc genes and methods based thereon |
-
2005
- 2005-05-27 JP JP2007515450A patent/JP2008500373A/ja active Pending
- 2005-05-27 US US11/140,024 patent/US7316998B2/en not_active Expired - Lifetime
- 2005-05-27 US US11/597,182 patent/US20100183695A1/en not_active Abandoned
- 2005-05-27 KR KR1020067027257A patent/KR20070026650A/ko not_active Withdrawn
- 2005-05-27 EP EP05780089A patent/EP1755648A2/en not_active Withdrawn
- 2005-05-27 AU AU2005247508A patent/AU2005247508A1/en not_active Abandoned
- 2005-05-27 WO PCT/US2005/018928 patent/WO2005115439A2/en not_active Ceased
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2006
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2007
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2012
- 2012-06-26 US US13/533,733 patent/US20130029908A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001526535A (ja) * | 1997-04-29 | 2001-12-18 | リジェネロン ファーマシューティカルズ，インコーポレイテッド | ヒトケルベロスタンパク質 |
| WO2003072714A2 (en) * | 2002-02-21 | 2003-09-04 | Wyeth | Follistatin domain containing proteins |
Also Published As
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| KR20070026650A (ko) | 2007-03-08 |
| US20090192080A1 (en) | 2009-07-30 |
| WO2005115439A2 (en) | 2005-12-08 |
| IL179602A0 (en) | 2007-05-15 |
| CA2567810A1 (en) | 2005-12-08 |
| US20130029908A1 (en) | 2013-01-31 |
| US20060025340A1 (en) | 2006-02-02 |
| US7981857B2 (en) | 2011-07-19 |
| EP1755648A2 (en) | 2007-02-28 |
| WO2005115439A9 (en) | 2006-02-02 |
| AU2005247508A1 (en) | 2005-12-08 |
| US20100183695A1 (en) | 2010-07-22 |
| WO2005115439A3 (en) | 2007-09-13 |
| US7316998B2 (en) | 2008-01-08 |
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