JP2008500363A - 新規化合物、該化合物を含む医薬組成物、および該化合物の使用方法 - Google Patents

新規化合物、該化合物を含む医薬組成物、および該化合物の使用方法 Download PDF

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Publication number
JP2008500363A
JP2008500363A JP2007515318A JP2007515318A JP2008500363A JP 2008500363 A JP2008500363 A JP 2008500363A JP 2007515318 A JP2007515318 A JP 2007515318A JP 2007515318 A JP2007515318 A JP 2007515318A JP 2008500363 A JP2008500363 A JP 2008500363A
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JP
Japan
Prior art keywords
compound
pharmaceutical composition
alkyl
fas
cells
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Pending
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JP2007515318A
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English (en)
Japanese (ja)
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JP2008500363A5 (enExample
Inventor
ジル・エム・スターディバント
クレイグ・エイ・タウンゼント
スーザン・エム・メドゴールチ
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Fasgen LLC
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Fasgen LLC
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Publication date
Application filed by Fasgen LLC filed Critical Fasgen LLC
Publication of JP2008500363A publication Critical patent/JP2008500363A/ja
Publication of JP2008500363A5 publication Critical patent/JP2008500363A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/32—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2007515318A 2004-05-26 2005-05-25 新規化合物、該化合物を含む医薬組成物、および該化合物の使用方法 Pending JP2008500363A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57463904P 2004-05-26 2004-05-26
PCT/US2005/018443 WO2005117590A2 (en) 2004-05-26 2005-05-25 Novel compounds, pharmaceutical compositions containing same, and methods of use for same

Publications (2)

Publication Number Publication Date
JP2008500363A true JP2008500363A (ja) 2008-01-10
JP2008500363A5 JP2008500363A5 (enExample) 2008-07-17

Family

ID=35463277

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007515318A Pending JP2008500363A (ja) 2004-05-26 2005-05-25 新規化合物、該化合物を含む医薬組成物、および該化合物の使用方法

Country Status (13)

Country Link
US (1) US20090005435A1 (enExample)
EP (1) EP1758577A4 (enExample)
JP (1) JP2008500363A (enExample)
KR (1) KR20070095754A (enExample)
CN (1) CN101022792A (enExample)
AU (1) AU2005249437A1 (enExample)
BR (1) BRPI0510397A (enExample)
CA (1) CA2568639A1 (enExample)
IL (1) IL179530A0 (enExample)
MX (1) MXPA06013687A (enExample)
RU (1) RU2006146051A (enExample)
WO (1) WO2005117590A2 (enExample)
ZA (1) ZA200700024B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100168218A1 (en) * 2005-07-26 2010-07-01 Kuhajda Francis P Method of reducing food intake
EP2083831B1 (en) * 2006-09-22 2013-12-25 Merck Sharp & Dohme Corp. Method of treatment using fatty acid synthesis inhibitors
CA2701649C (en) * 2007-10-05 2016-05-24 Genzyme Corporation Method of treating polycystic kidney diseases with ceramide derivatives
WO2010118324A2 (en) 2009-04-09 2010-10-14 Nuclea Biotechnologies, LLC Antibodies against fatty acid synthase
CA2884355C (en) * 2012-09-07 2022-05-17 Janssen Pharmaceutica Nv Imidazolin-5-one derivative useful as fasn inhobitors for the treatment of cancer
US11202795B2 (en) 2014-11-20 2021-12-21 Vib Vzw Means and methods for treatment of early-onset Parkinson's disease
MX2022009078A (es) 2020-01-23 2022-08-15 Basf Se Formulaciones de ppo que contienen sulfatos de eter.
KR20230097101A (ko) 2020-10-27 2023-06-30 바스프 에스이 살충제 마이크로에멀젼 조성물
WO2022167577A1 (en) 2021-02-05 2022-08-11 Basf Se Liquid herbicidal compositions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004005277A1 (en) * 2002-07-09 2004-01-15 Fasgen, Inc. Novel compunds, pharmaceutical compositions containing same, and methods of use for same
JP2005523270A (ja) * 2002-02-08 2005-08-04 ジョーンズ・ホプキンス・ユニバーシティ・スクール・オブ・メディシン 体重を減少させる方法としてのｃｐｔ−１の促進

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3427847A1 (de) * 1983-12-09 1985-06-13 Bayer Ag, 5090 Leverkusen Thiolan-2,4-dion-3-carboxamide
US5759837A (en) * 1989-01-17 1998-06-02 John Hopkins University Chemotherapy for cancer by inhibiting the fatty acid biosynthetic pathway
US5614551A (en) * 1994-01-24 1997-03-25 The Johns Hopkins University Inhibitors of fatty acid synthesis as antimicrobial agents
US5981575A (en) * 1996-11-15 1999-11-09 Johns Hopkins University, The Inhibition of fatty acid synthase as a means to reduce adipocyte mass

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005523270A (ja) * 2002-02-08 2005-08-04 ジョーンズ・ホプキンス・ユニバーシティ・スクール・オブ・メディシン 体重を減少させる方法としてのｃｐｔ−１の促進
WO2004005277A1 (en) * 2002-07-09 2004-01-15 Fasgen, Inc. Novel compunds, pharmaceutical compositions containing same, and methods of use for same

Also Published As

Publication number Publication date
CN101022792A (zh) 2007-08-22
RU2006146051A (ru) 2008-07-10
EP1758577A4 (en) 2010-05-05
ZA200700024B (en) 2008-06-25
KR20070095754A (ko) 2007-10-01
EP1758577A2 (en) 2007-03-07
IL179530A0 (en) 2007-05-15
WO2005117590A3 (en) 2006-07-27
WO2005117590A2 (en) 2005-12-15
US20090005435A1 (en) 2009-01-01
MXPA06013687A (es) 2007-10-18
AU2005249437A1 (en) 2005-12-15
CA2568639A1 (en) 2005-12-15
BRPI0510397A (pt) 2007-11-13

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